Search results for "Bauman"
showing 10 items of 50 documents
Rapid, cost-effective, sensitive and quantitative detection of Acinetobacter baumannii from pneumonia patients
2011
Background and Objectives: Pneumonia with Acinetobacter baumannii has a major therapeutic problem in health care settings. Decision to initiate correct antibiotic therapy requires rapid identification and quantification of organism. The aim of this study was to develop a rapid and sensitive method for direct detection of A. baumannii from respiratory specimens. Materials and Methods: A Taqman real time PCR based on the sequence of blaoxa-51 was designed and used for direct detection of A. baumannii from 361 respiratory specimens of patients with pneumonia. All specimens were checked by conventional bacteriology in parallel. Results: The new real time PCR could detect less than 200 cfu per m…
Drug resistance patterns of bacteria isolated from patients with nosocomial pneumonia at Tehran hospitals during 2009-2011
2013
Introduction: Nosocomial pneumonia remains an important cause of mortality and morbidity worldwide. Surveillance programs play an important role in the identification of common etiologic agents and local patterns of antimicrobial resistance. Methodology: In this study we determined the frequency and antimicrobial susceptibility of pathogens isolated from patients with nosocomial pneumonia during 2009 to 2011. Results: A total of 642 bacteria were isolated from 516 suspected samples. Acinetobacter baumannii (21.1%, n = 136), was the commonest isolated pathogen followed by Pseudomonas aeruginosa (17.4%, n = 112) , Staphylococcus aureus (15.8%, n = 102) and enterococci (8.4% n = 54). The most …
Cladosins L-O, new hybrid polyketides from the endophytic fungus Cladosporium sphaerospermum WBS017
2019
Abstract The endophytic fungus Cladosporium sphaerospermum WBS017 was obtained from healthy bulbs of Fritillaria unibracteata var. wabuensis. Fermentation of C. sphaerospermum on solid rice medium yielded three new hybrid polyketides, cladosins L−N (1–3), and a known derivative cladodionen (4). Further cultivation of this fungus on white bean medium afforded an additional new hybrid polyketide, cladosin O (5) along with three known analogues (6–8). The structures of the new compounds were elucidated using a combination of NMR and HRESIMS data. The absolute configurations of compounds 2 and 3 were determined by Mosher’s method and TDDFT-ECD calculations. All isolated compounds were evaluated…
High susceptibility of MDR and XDR Gram-negative pathogens to biphenyl-diacetylene-based difluoromethyl-allo-threonyl-hydroxamate LpxC inhibitors
2016
International audience; Inhibitors of uridine diphosphate-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase (LpxC, which catalyses the first, irreversible step in lipid A biosynthesis) are a promising new class of antibiotics against Gram-negative bacteria. The objectives of the present study were to: (i) compare the antibiotic activities of three LpxC inhibitors (LPC-058, LPC-011 and LPC-087) and the reference inhibitor CHIR-090 against Gram-negative bacilli (including MDR and XDR isolates); and (ii) investigate the effect of combining these inhibitors with conventional antibiotics.MethodsMICs were determined for 369 clinical isolates (234 Enterobacteriaceae and 135 non-fermentati…
Pseudomonas aeruginosa un Acinetobacter baumanii jutība pret antibakteriālajiem līdzekļiem
2018
Pseudomonas aeruginosa un Acinetobacter baumannii ir galvenie ar veselības aprūpes saistīto infekciju (VASI) izraisītāji. Šo patogēnu rezistence pret antibakteriālajiem līdzekļiem pēdējo gadu laikā ir strauji palielinājusies, un ir viena no aktuālākajām problēmām mūsdienās. Darba mērķis: izpētīt gramnegatīvo baktēriju P. aeruginosa un A. baumannii jutību pret antibakteriālajiem līdzekļiem, salīdzināt antibakteriālās rezistences izmaiņas divu gadu laikā. Uzdevumi: identificēt no elpceļiem iegūtos izolātus ar BBL™ Crystal™ sistēmu, veikt antibakteriālo līdzekļu jutības testus, izmantojot Bauer – Kirby disku difūzijas testu un E – testu, fenotipēšanu veikt pēc antibiogrammām. Rezultātus apko…
Acinetobacter baumannii un Pseudomonas aeruginosa antibakteriālās rezistences noteikšana, lietojot fenotipiskās un molekulāri bioloģiskās metodes
2020
Acinetobacter baumannii un Pseudomonas aeruginosa ir gan Latvijā, gan visā Eiropā bieži sastopami intrahospitāli patogēni, pret kuriem antibiotiku rezistence pieaug ik gadu. Visbiežāk tie skar imūnsupresētus cilvēkus, apdraudot veselību un dzīvību. Darba mērķis: Noteikt A.baumannii un P. aeruginosa jutību pret antibakteriālajiem līdzekļiem 2019. gadā un salīdzināt rezistences izmaiņas ar 2017. gadu, kā arī ar molekulāri bioloģisko metodi identificēt baktēriju sugas. Uzdevumi: 1.No elpceļu paraugiem ar BBL CrystalTM identifikācijas sistēmām identificēt izolātus. 2. Noteikt antimikrobiālo jutību, izmantojot Bauer-KirbyTM disku difūzijas testu un MIC, lietojot ETM-testu. 3. Tipēt izdalīto bakt…
Dissemination of a Carbapenem-Resistant Acinetobacter baumannii Strain Belonging to International Clone II/Sequence Type 2 and Harboring a Novel AbaR…
2013
ABSTRACT An outbreak of hospital-acquired Acinetobacter baumannii infections, caused by a bla OXA-23 -positive carbapenem-resistant strain belonging to international clone II/ST2, was detected in Latvia. The strain was partially equipped with the armA gene and the intI1-aacA4-catB8-aadA1-qacE Δ 1 class 1 integron. In addition, the strain carried AbaR25, a novel AbaR4-like resistance island of ∼46,500 bp containing structures similar to the previously described AbaR22 and Tn 6167 islands. AbaR25 was characterized by the occurrence of a second copy of Tn 6022a interrupted by Tn 2006 carrying the bla OXA-23 gene.
La classe in Bauman: residuo della memoria o persistenza sociale?
2020
Memorie di classe è un testo molto complesso e articolato, che si inscrive a pieno titolo nella tradizione sociologica degli studi sul mutamento sociale e culturale. La proposta in esso avanzata persegue diversi obiettivi. Il più esplicito e importante riguarda il tentativo di dar corpo ad una genealogia del concetto di classe per poi abbandonarlo, dimostrandone la non utilità, sia come categoria esplicativa dei fenomeni sociali che caratterizzano il modo di produzione capitalistico e il suo sviluppo sino alla cosiddetta globalizzazione, sia nel senso dell’identificazione di esso con il soggetto della trasformazione economica e sociale, come invece pensava Karl Marx. Ma all’interno di quest…
Memorie di classe. Preistoria e sopravvivenza di un concetto
2020
Memorie di classe è un testo molto complesso e articolato, che si inscrive a pieno titolo nella tradizione sociologica degli studi sul mutamento sociale e culturale. La proposta in esso avanzata persegue diversi obiettivi. Il più esplicito e importante riguarda il tentativo di dar corpo ad una genealogia del concetto di classe per poi abbandonarlo, dimostrandone la non utilità, sia come categoria esplicativa dei fenomeni sociali che caratterizzano il modo di produzione capitalistico e il suo sviluppo sino alla cosiddetta globalizzazione, sia nel senso dell’identificazione di esso con il soggetto della trasformazione economica e sociale, come invece pensava Karl Marx. Ma all’interno di quest…
Nowist Time: quando l'accelerazione supera il tempo
2019
12 marzo 1989, CERN di Ginevra – Tim Berners-Lee presenta al suo supervisore la prima idea del World Wide Web elaborata grazie all’osservazione della modalità di trasmissione di informazioni tramite video adoperato da ricercatori italiani che lavoravano con lui. Meno di vent’anni dopo, nel 2005, Zygmunt Bauman, esaminando la società post-moderna, mette in evidenza come sia cambiata la temporalità in un mondo che definisce «liquido». Alla ricerca perenne di allungare sempre più possibile il presente per riempirlo di esperienze della durata sempre più labile, l’uomo perde il desiderio dell’eternità. Ciò che conta per l’uomo dalla vita liquida non è la durata, ma la velocità a cui riesce a com…