Search results for "Bed"
showing 10 items of 1605 documents
Sparse Manifold Clustering and Embedding to discriminate gene expression profiles of glioblastoma and meningioma tumors.
2013
Sparse Manifold Clustering and Embedding (SMCE) algorithm has been recently proposed for simultaneous clustering and dimensionality reduction of data on nonlinear manifolds using sparse representation techniques. In this work, SMCE algorithm is applied to the differential discrimination of Glioblastoma and Meningioma Tumors by means of their Gene Expression Profiles. Our purpose was to evaluate the robustness of this nonlinear manifold to classify gene expression profiles, characterized by the high-dimensionality of their representations and the low discrimination power of most of the genes. For this objective, we used SMCE to reduce the dimensionality of a preprocessed dataset of 35 single…
Reproducing kernel hilbert spaces regression methods for genomic assisted prediction of quantitative traits.
2008
Abstract Reproducing kernel Hilbert spaces regression procedures for prediction of total genetic value for quantitative traits, which make use of phenotypic and genomic data simultaneously, are discussed from a theoretical perspective. It is argued that a nonparametric treatment may be needed for capturing the multiple and complex interactions potentially arising in whole-genome models, i.e., those based on thousands of single-nucleotide polymorphism (SNP) markers. After a review of reproducing kernel Hilbert spaces regression, it is shown that the statistical specification admits a standard mixed-effects linear model representation, with smoothing parameters treated as variance components.…
Global Scale IB AMSR2 Vegetation Optical Depth at X-Band
2021
Vegetation Optical Depth (VOD) plays an increasingly important role in studying global carbon, water and energy transformation [1], [2]. This study explores the performance of the X-MEB (X-band microwave emission of the biosphere) model at global scale. Similar to the L-MEB model, the X-MEB model, built by INRAE (Institut national de recherche pour l'agriculture, l'alimentation et l'environnement) Bordeaux, aims to retrieve VOD (referred to as IB X-VOD) at X-band. To avoid the ill-posed problem caused by retrieving two parameters of interest (soil moisture (SM) and VOD) from mono-angular and dual-polarized observations (AMSR2), which are strongly correlated, we used the ERA5 SM product as a…
Effects of the dual sodium-glucose linked transporter inhibitor, licogliflozinvsplacebo or empagliflozin in patients with type 2 diabetes and heart f…
2020
Aims Explore the efficacy, safety and tolerability of the dual sodium-glucose cotransporter (SGLT) 1 and 2 inhibitor, licogliflozin in patients with type-2 diabetes mellitus (T2DM) and heart failure. Methods This multicentre, parallel-group phase IIA study randomized 125 patients with T2DM and heart failure (New York Heart Association II-IV; plasma N-terminal pro b-type natriuretic peptide [NT-proBNP] >300 pg/mL) to licogliflozin (2.5 mg, 10 mg, 50 mg) taken at bedtime, empagliflozin (25 mg) or placebo (44 patients completed the study). The primary endpoint was change from baseline in NT-proBNP after 12 weeks. Secondary endpoints included change from baseline in glycated haemoglobin, fas…
A double mean field equation related to a curvature prescription problem
2019
We study a double mean field-type PDE related to a prescribed curvature problem on compacts surfaces with boundary. We provide a general blow-up analysis, then a Moser-Trudinger inequality, which gives energy-minimizing solutions for some range of parameters. Finally, we provide existence of min-max solutions for a wider range of parameters, which is dense in the plane if $��$ is not simply connected.
Impact of trace metals from past mining on the aquatic ecosystem: a multi-proxy approach in the Morvan (France).
2014
10 pages; International audience; This study seeks to determine to what extent trace metals resulting from past mining activities are transferred to the aquatic ecosystem, and whether such trace metals still exert deleterious effects on biota. Concentrations of Cd, Cu, Pb and Zn were measured in streambed sediments, transplanted bryophytes and wild brown trout. This study was conducted at two scales: (i) the entire Morvan Regional Nature Park and (ii) three small watersheds selected for their degree of contamination, based on the presence or absence of past mining sites. The overall quality of streambed sediments was assessed using Sediment Quality Indices (SQIs). According to these standar…
Specific immunohistochemical identification of Candida albicans in paraffin-embedded tissue with a new monoclonal antibody (1B12).
1995
In invasive candidiasis, the identification of Candida organisms in tissue samples or in normally sterile fluids is essential for an accurate diagnosis. Species identification is an important clue for the source of infection and in epidemiological studies. In this article, the authors have tested the value of a new monoclonal antibody (1B12) to detect C albicans in culture by immunofluorescence, and in tissue samples by immunohistochemistry. MAb 1B12 was found to specifically recognize C albicans , does not cross-react with other Candida species or other structurally similar fungi, and is very sensitive and specific in paraffin-embedded tissue, having no reactivity in normal human tissues o…
The alanine detector in BNCT dosimetry: Dose response in thermal and epithermal neutron fields
2014
Purpose: The response of alanine solid state dosimeters to ionizing radiation strongly depends on particle type and energy. Due to nuclear interactions, neutron fields usually also consist of secondary particles such as photons and protons of diverse energies. Various experiments have been carried out in three different neutron beams to explore the alanine dose response behavior and to validate model predictions. Additionally, application in medical neutron fields for boron neutron capture therapy is discussed. Methods: Alanine detectors have been irradiated in the thermal neutron field of the research reactor TRIGA Mainz, Germany, in five experimental conditions, generating different secon…
Fast prototyping of a SoC-based smart-camera: a real-time fall detection case study
2014
International audience; Smart camera, i.e. cameras that are able to acquire and process images in real-time, is a typical example of the new embedded computer vision systems. A key example of application is automatic fall detection, which can be useful for helping elderly people in daily life. In this paper, we propose a methodology for development and fast-prototyping of a fall detection system based on such a smart camera, which allows to reduce the development time compared to standard approaches. Founded on a supervised classification approach, we propose a HW/SW implementation to detect falls in a home environment using a single camera and an optimized descriptor adapted to real-time t…
Embedded System Study for Real Time Boosting Based Face Detection
2006
This paper describes a study for a real time embedded face detection system. Recently, the boosting based face detection algorithms proposed by [(Viola, P and Jone, M, 2001); (Lienhart, R, et al., 2003)] have gained a lot of attention and are considered as the fastest accurate face detection algorithms today. However, the embedded implementation of such algorithms into hardware is still a challenge, since these algorithms are heavily based on memory access. A sequential implementation model is built showing its lack of regularity in time consuming and speed of detection. We propose a parallel implementation that exploits the parallelism and the pipelining in these algorithms. This implement…