Search results for "Bene"
showing 10 items of 2408 documents
Los beneficios del mar: negocios e inversiones económicas de la oficialidad naval en el siglo XVIII
2019
Throughout the eighteenth century, the Spanish navy was extensively reformed and enhanced as a consequence of the new model of Monarchy that the Bourbons introduced. Among the measures adopted, it is remarkable the erection of the naval officers corps according to the needs and obligations that maritime war had in this century. This group becomes the paradigm of the new professionalization and new training approach, and its members had great relevance due to its great mobility around the empire and the power of the naval institution. This means that a part of the naval officers were placed in privileged positions and at the intersection of diverse political, social and economic networks. Th…
Wykorzystanie środków unijnych w obszarze edukacji w województwie opolskim w latach 2004 - 2015. Wybrane problemy
2017
Korzystanie przez Polskę ze środków unijnych bywa kontestowane. Wydaje się konieczna i rzetelna ocena w różnych obszarach naszego życia społecznego, zwłaszcza w edukacji, zakresu i sposobu ich wykorzystania. Środki unijne w dużym stopniu wsparły różne działania. Jednak od nas samych zależy na co je wykorzystamy i jak je spożytkujemy. Badania przeprowadzone na terenie województwa opolskiego i gmin z województw sąsiednich pozwalają na stwierdzenie, że środki te przyczyniły się do aktywizacji nauczycieli, dyrekcji szkół, gmin, placówek edukacyjnych w pozyskiwaniu środków na działania podnoszące poziom wiedzy i umiejętności uczniów. Z przeprowadzonych badań wynika, że środki pozyskane za sprawą…
Special Issue: Improvements for Resveratrol Efficacy
2017
International audience; Resveratrol is a well-known phenolic stilbene because of its presence in several edible plants and its proposed properties that are beneficial to human health [...].
Considerations on the Advantages and Disadvantages of Romania's Accession to the European Union
2015
Abstract After nine years from Romania's accession to the European Union, the advantages are sustained with specific statistical markers, which could have been more positive if the effect of certain identified causes (reduced administrative ability, political instability, extended corruption, high tax evasion etc.) would have been diminished. Counterbalancing the benefits of the accession the opinion polls show the disadvantages. If a poll conducted four years prior to the accession showed that 66% of Romania's population considered that the accession to the European Union would produce positive effects, after six years from the accession things have reversed and 58% of Romanians considered…
La funzione antielusiva del concetto di "beneficiario effettivo" nel sistema italiano tra diritto internazionale tributario e diritto dell'Unione eur…
2014
abstractita
Proanthocyanidins and Where to Find Them: A Meta-Analytic Approach to Investigate Their Chemistry, Biosynthesis, Distribution, and Effect on Human He…
2021
Proanthocyanidins (PACs) are a class of polyphenolic compounds that are attracting considerable interest in the nutraceutical field due to their potential health benefits. However, knowledge about the chemistry, biosynthesis, and distribution of PACs is limited. This review summarizes the main chemical characteristics and biosynthetic pathways and the main analytical methods aimed at their identification and quantification in raw plant matrices. Furthermore, meta-analytic approaches were used to identify the main plant sources in which PACs were contained and to investigate their potential effect on human health. In particular, a cluster analysis identified PACs in 35 different plant famili…
A role for peroxisome proliferator-activated receptor gamma in resveratrol-induced colon cancer cell apoptosis.
2014
Scope Resveratrol may function as a chemopreventive agent. A recent clinical study demonstrates a reduction in tumor cell proliferation in colorectal patients receiving repeated oral ingestion of resveratrol. However, gaps remain in our knowledge of the molecular mechanisms by which resveratrol exerts its chemopreventive effect. We have previously demonstrated that resveratrol induces apoptosis in colon cancer cells and that resveratrol can sensitize chemoresistant colon cancer cells to various drugs. Based on its ability to activate peroxisome proliferator-activated receptor gamma (PPARγ) in colon cancer cells, we sought to determine the implication of this nuclear transcription factor in …
Resveratrol post-transcriptionally regulates pro-inflammatory gene expression via regulation of KSRP RNA binding activity
2014
Resveratrol shows beneficial effects in inflammation-based diseases like cancer, cardiovascular and chronic inflammatory diseases. Therefore, the molecular mechanisms of the anti-inflammatory resveratrol effects deserve more attention. In human epithelial DLD-1 and monocytic Mono Mac 6 cells resveratrol decreased the expression of iNOS, IL-8 and TNF-α by reducing mRNA stability without inhibition of the promoter activity. Shown by pharmacological and siRNA-mediated inhibition, the observed effects are SIRT1-independent. Target-fishing and drug responsive target stability experiments showed selective binding of resveratrol to the RNA-binding protein KSRP, a central post-transcriptional regul…
Allocation of Ambipolar Charges on an Organic Diradical with a Vinylene-Phenylenediyne Bridge.
2021
Two redox and magnetically active perchlorotriphenylmethyl (• PTM) radical units have been connected as end-capping groups to a bis(phenylene)diyne chain through vinylene linkers. Negative and positive charged species have been generated, and the influence of the bridge on their stabilization is discussed. Partial reduction of the electron-withdrawing • PTM radicals results in a class-II mixed-valence system with the negative charge located on the terminal PTM units, proving the efficiency of the conjugated chain for the electron transport between the two terminal sites. Counterintuitively, the oxidation process does not occur along the electron-rich bridge but on the vinylene units. The • …