Search results for "Beni culturali"
showing 10 items of 1017 documents
Pratiche di conoscenza e fruizione collettiva per un’accessibilità fisica e culturale del patrimonio monumentale
2022
I-Access, progetto Interreg Italia-Malta, si interroga sui temi dell’accessibilità fisica e culturale nei centri storici delle città di Palermo e La Valletta, accomunati da storie parallele di uomini, monumenti, spazi urbani. E lo fa con la costituzione di un gruppo formato da esperti di restauro architettonico e di design della comunicazione visiva, facendo dialogare i due ambiti disciplinari che condividono metodologie e strumenti di lavoro. In tal modo i dati materici e storiografici raccolti dai primi vengono tradotti in configurazioni visibili, leggibili, ordinate, in cui la nuova struttura narrativa consente la corretta accessibilità culturale del monumento e della sua storia. Insieme…
MQ, MUSEUM QUARTIER, WIEN
2009
Con l’articolo che segue si apre una nuova sezione della rivista dedicata al design della comunicazione, che offrirà al lettore uno spazio di conoscenza e riflessione su temi che riguardano in vario modo la comunicazione visiva e il sistema dei beni culturali. Tema importante e attuale del quale mi occupo ormai da parecchi anni, sia in termini di didattica sia in termini di ricerca, e che mi ha condotto alla pubblicazione del libro La comunicazione dei beni culturali, edito da Lupetti. Gli articoli riguarderanno le principali realtà museali o i luoghi della cultura, a livello nazionale e internazionale, e la descrizione dei sistemi di identità visiva da loro adottati. In questo cercherò sem…
Thermal aggregation of proteins in presence of metal ions.
2008
The study of the aggregation processes in presence of metal ions is an essential step for understanding the key role of metals in protein-protein and protein-solvent interactions. Indeed, the presence of metal ions can radically change the main features of the standard denaturation/aggregation processes and such effects result to be strongly dependent on the kind of metal and on its concentration. Metal ions have an active role in thermal aggregation and cold set gelation processes. These processes are intrinsically different, but both are based on the proteins ability to form aggregates.
Ricordo di Vincenzo Tusa (1921-2009)
2011
Viene illustrata la figura del Soprintendente e archeologo Vincenzo Tusa come uomo e come studioso: le sue ricerche e scavi nella Siclia occidentale (Solunto, Selinunte, Mozia, Segesta, etc.), le sue molteplici attività a difesa dei Beni culturali, e le sue opere e scritti scientifici.
The BioS4You European project: An innovative way to effectively engage Z-generation students in STEM disciplines
2021
In this contribution, we present the BioS4You project and analyse the results obtained in the first 18 months of its activity. The “Bio-Inspired STEM topics for engaging young generations” (BioS4You) Erasmus+ KA2 Innovation project aims to bridge the gap between STEM national curricula (which include Science, Technology, Engineering, and Mathematics) and the needs of Z-generation students, uninterested to basic themes, but enthusiastic in issues related to environmental, social, and health concerns. The BioS4You project engages young learners in STEM subjects, starting with current issues of interest for them, as the social and environmental impact of new technologies, connecting STEM conce…
Protein dynamical transition vs. liquid-liquid phase transition in protein hydration water
2013
In this work, we compare experimental data on myoglobin hydrated powders from elastic neutron scattering, broadband dielectric spectroscopy, and differential scanning calorimetry. Our aim is to obtain new insights on the connection between the protein dynamical transition, a fundamental phenomenon observed in proteins whose physical origin is highly debated, and the liquid-liquid phase transition (LLPT) possibly occurring in protein hydration water and related to the existence of a low temperature critical point in supercooled water. Our results provide a consistent thermodynamic/dynamic description which gives experimental support to the LLPT hypothesis and further reveals how fundamental …
Unsupervised clustering method for pattern recognition in IIF images
2017
Autoimmune diseases are a family of more than 80 chronic, and often disabling, illnesses that develop when underlying defects in the immune system lead the body to attack its own organs, tissues, and cells. Diagnosis of autoimmune pathologies is based on research and identification of antinuclear antibodies (ANA) through indirect immunofluorescence (IIF) method and is performed by analyzing patterns and fluorescence intensity. We propose here a method to automatically classify the centromere pattern based on the grouping of centromeres on the cells through a clustering K-means algorithm. The described method was tested on a public database (MIVIA). The results of the test showed an Accuracy…
Determinazione della componente gamma nella colone termica del reattore TRIGA di Pavia tramite Dosimetri ESR di alanina
2016
Negli ultimi anni il crescente interesse verso la radioterapia a cattura neutronica (internazionalmente nota come Neutron Capture Therapy - NCT) per il trattamento di neoplasie ha stimolato diverse attività di ricerca finalizzate alla caratterizzazione del fascio utilizzato e all'ottimizzazione delle procedure radioterapiche. Tra i vari sistemi dosimetrici trovano largo impiego i rivelatori a stato solido ESR (Risonanza di Spin Elettronico) a base di alanina che presentano diversi vantaggi come la tessuto equivalenza, la linearità della risposta in un ampio intervallo di dose, l'elevata stabilità dei radicali liberi radioindotti, la non distruttività della lettura del dosimetro e il basso c…
Transportan 10 Induces Perturbation and Pores Formation in Giant Plasma Membrane Vesicles Derived from Cancer Liver Cells
2023
Continuous progress has been made in the development of new molecules for therapeutic purposes. This is driven by the need to address several challenges such as molecular instability and biocompatibility, difficulties in crossing the plasma membrane, and the development of host resistance. In this context, cell-penetrating peptides (CPPs) constitute a promising tool for the development of new therapies due to their intrinsic ability to deliver therapeutic molecules to cells and tissues. These short peptides have gained increasing attention for applications in drug delivery as well as for their antimicrobial and anticancer activity but the general rules regulating the events involved in cell…
Thioflavin T Promotes Aβ(1−40) Amyloid Fibrils Formation
2015
Fibrillogenesis of the small peptide Aβ(1-40) is considered to be the hallmark of Alzheimer's disease. Some evidence indicates small oligomers, rather than mature fibrils, as the key cytotoxic agents. The fluorescent dye Thioflavin T (ThT) is often used to detect amyloid deposits in both in vivo and in vitro experiments, and it is used to study kinetic measurements, under the fundamental hypothesis that this probe does not influence the aggregation processes. We report experimental data showing that ThT may promote the Aβ(1-40) peptide amyloid aggregation changing solvent-peptide interactions and stabilizing more ordered β-like conformation. This finding has a two-fold importance: It is a f…