Search results for "Beni"
showing 10 items of 1421 documents
La gestione del demanio marittimo nella evoluzione del paesaggio costiero
2017
Le linee di costa sono da sempre il luogo fisico a maggiore gradiente di immaterialità, a più alta densità di valore esperienziale, a più elevata tensione localizzativa. Con specifico riferimento all’uso dei litorali, alla loro conservazione e valorizzazione, all’accesso a essi, in quanto commons e heritage-goods, l’articolo avanza alcune considerazioni generali che richiamano temi di pianificazione ampi e profonde questioni valutative. Lo studio proposto intende indicare alcune componenti strutturali (in senso paesaggistico), caratteristiche salienti (in senso assiologico) e potenzialità (in senso progettuale) del patrimonio costiero. Il lavoro prende spunto dall’osservazione di alcuni cas…
Hydration dependence of mean square displacements, relaxation times and calorimetric glass transition in myoglobin hydrated powders
2012
A calorimetric study of ternary protein-trehalose-water systems: matrix glass transition and protein thermal denaturation
2010
Anharmonic onsets in polypeptides revealed by neutron scattering: experimental ecidences and quantitative description of energy resolution dependence
2012
Immobilization of proteins in silica gel: Biochemical and biophysical properties
2015
The development of silica-based sol-gel techniques compatible with the retention of protein structure and function started more than 20 years ago, mainly for the design of biotechnological devices or biomedical applications. Silica gels are optically transparent, exhibit good mechanical stability, are manufactured with different geometries, and are easily separated from the reaction media. Biomolecules encapsulated in silica gel normally retain their structural and functional properties, are stabilized with respect to chemical and physical insults, and can sometimes exhibit enhanced activity in comparison to the soluble form. This review briefly describes the chemistry of protein encapsulat…
Investigating protein structure and dynamics through wide-angle X-ray solution scattering
2016
Wide-angle X-ray scattering (WAXS) is a powerful tool that can be used to gain information on the structure and dynamics of proteins and other biomolecules in solution. Improved methods for the calculation of WAXS patterns from available or putative protein models allow to better exploit the structural information contained in the experimental data. These methods, together with recent applications of static and time-resolved WAXS, are briefly reviewed.
Phasor-FLIM for a direct investigation of Transportan 10 interactions with model membranes
2023
Transportan 10 (TP10), a short and positive charged peptide, belonging to the family of the cell penetrating peptides has gained increasing attention for its antimicrobial and anticancer activity but also for its applications in drug delivery as it is able to translocate therapeutic molecules in cellular environment. Due to the complexity of the phenomena involved in cellular uptake and following processes, which strongly depend on the membrane lipid composition, structural details of the peptide (e.g., charge, hydrophobicity, steric hindrance) and environmental conditions, it is not easy to understand the general rules governing them. Here, we combine spectroscopic techniques and fluoresce…