Search results for "Benzoxepins"

showing 3 items of 3 documents

Determination of fatty alcohol ethoxylates and alkylether sulfates by anionic exchange separation, derivatization with a cyclic anhydride and liquid …

2011

A method for the separation, characterization and determination of fatty alcohol ethoxylates (FAE) and alkylether sulfates (AES) in industrial and environmental samples is described. Separation of the two surfactant classes was achieved in a 50:50 methanol-water medium by retaining AES on a strong anionic exchanger (SAX) whereas most FAE were eluted. After washing the SAX cartridges to remove cations, the residual hydrophobic FAE were eluted by increasing methanol to 80%. Finally, AES were eluted using 80:20 and 95:5 methanol-concentrated aqueous HCl mixtures. Methanol and water were removed from the FAE and AES fractions, and the residues were dissolved in 1,4-dioxane. In this medium, este…

AnionsEthylene OxideFatty alcoholBiochemistryAnalytical ChemistryDioxanesSurface-Active Agentschemistry.chemical_compoundAcetic acidSeawaterDerivatizationChromatography High Pressure LiquidPhthalic anhydrideAqueous solutionChromatographyEsterificationSulfatesElutionOrganic ChemistryExtraction (chemistry)General MedicineChromatography Ion ExchangechemistryMethanolFatty AlcoholsDibenzoxepinsJournal of Chromatography A
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Cytotoxicity of botanicals and isolated phytochemicals from Araliopsis soyauxii Engl. (Rutaceae) towards a panel of human cancer cells.

2020

Abstract Ethnopharmacological relevance Araliopsis soyauxii Engl. (Rutaceae) is a Cameroonian medicinal plant traditionally used to treat lung diseases, malaria, and gonorrhea. It has been demonstrated that infectious disease contribute to about 20% of all human tumours. Aims of the study (1) To perform a phytochemical investigation of the dichloromethane-methanol 1:1 extracts of the bark (ASB), roots (ASR), and leaves (ASL) from Araliopsis soyauxii; (2) to evaluate the cytotoxicity of extracts and isolated compounds; (3) to determine the mode of induction of apoptosis of ASB and kihadanin B (12). Materials and methods Fourteen constituents of the crude extracts were isolated by column chro…

LimoninsPhytochemicalsApoptosisFlow cytometry03 medical and health sciencesInhibitory Concentration 500302 clinical medicineAnnexinNeoplasmsDrug DiscoverymedicineCytotoxic T cellBenzoxepinsHumansCytotoxicityRutaceae030304 developmental biologyPharmacologychemistry.chemical_classificationMembrane Potential Mitochondrial0303 health sciencesReactive oxygen speciesmedicine.diagnostic_testDose-Response Relationship DrugChemistryPlant ExtractsCell Cycle CheckpointsHep G2 CellsCell cycleHCT116 CellsMolecular biologyAntineoplastic Agents PhytogenicMitochondriaOxidative StressPhytochemicalApoptosis030220 oncology & carcinogenesisApoptosis Regulatory ProteinsReactive Oxygen SpeciesSignal TransductionJournal of ethnopharmacology
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Characterization of the alcoholic fraction of vegetable oils by derivatization with diphenic anhydride followed by high-performance liquid chromatogr…

2008

Abstract Aliphatic and triterpene alcohols present in vegetable oils have been identified and determined by HPLC using UV–vis and MS detection after previous derivatization with diphenic anhydride. The alcoholic fraction was obtained by saponification, extraction and TLC (according to the European Union official procedure). Derivatization was performed in tetrahydrofuran in the presence of suspended grinded urea, which increases the reaction rate and yield. Derivatized extracts were chromatographed on a C8 column using gradient elution with acetonitrile/water mixtures containing 0.1% acetic acid, with UV–vis followed by negative-ion mode MS detection. Using linear discriminant analysis of t…

Resolution (mass spectrometry)Fraction (chemistry)Chemical FractionationSensitivity and SpecificityBiochemistryHigh-performance liquid chromatographyMass SpectrometryAnalytical ChemistryAcetic acidchemistry.chemical_compoundPlant Oilsmedia_common.cataloged_instanceEuropean unionDerivatizationChromatography High Pressure Liquidmedia_commonChromatographyEsterificationOrganic ChemistryExtraction (chemistry)Reproducibility of ResultsGeneral MedicineModels ChemicalchemistryAlcoholsMultivariate AnalysisDibenzoxepinsSaponificationJournal of Chromatography A
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