Search results for "Bile"
showing 10 items of 2148 documents
Supporting Mobile Virtual Team’s Coordination with SOA-Based Active Entities
2007
The use of IT solutions to support preparedness, response and recovery process has been envisioned as a possible way to improve the support for collaboration among the actors participating in mobile teams operating under constrained scenarios. Software applications supporting mobility have typically been conceived as functional extensions of centralized enterprise systems hosted on corporate servers. However, in this work, we focus on those mobile scenarios which go one step further in terms of interoperability requirements. This proposal aims to support the design, deployment and execution of ad-hoc collaborative business processes (workflows) in mobile networks, operating under constraine…
La riforma degli articoli 9 e 41 della Costituzione e la valorizzazione dell'ambiente.
2022
Con la riforma degli art. 9 e 41 della Costituzione, approvata l’8 febbraio 2022, l’ambiente entra nella Costituzione tra i principi fondamentali ed in qualità di limite all’esercizio dell’attività economica. Il saggio propone una lettura della riforma in grado di avvalorare quell’orientamento che, sin dal secolo scorso, propugnava la ricostruzione dell’ambiente come diritto fondamentale della persona, in linea con la valorizzazione dello stesso quale bene distinto dal paesaggio, in una prospettiva esistenzialista di tutela della persona. La modifica introdotta, secondo l’autore, colma un vuoto costituzionale, divenuto insostenibile alla luce degli sviluppi della tutela ambientale, così com…
Synthesis and Structure-Activity Relationships of Amino Acid Conjugates of Cholanic Acid as Antagonists of the EphA2 Receptor
2013
The Eph–ephrin system plays a critical role in tumor growth and vascular functions during carcinogenesis. We had previously identified cholanic acid as a competitive and reversible EphA2 antagonist able to disrupt EphA2-ephrinA1 interaction and to inhibit EphA2 activation in prostate cancer cells. Herein, we report the synthesis and biological evaluation of a set of cholanic acid derivatives obtained by conjugation of its carboxyl group with a panel of naturally occurring amino acids with the aim to improve EphA2 receptor inhibition. Structure-activity relationships indicate that conjugation of cholanic acid with linear amino acids of small size leads to effective EphA2 antagonists whereas …
Evaluating the citywide Edinburgh 20mph speed limit intervention effects on traffic speed and volume: A pre-post observational evaluation.
2021
Objectives Traffic speed is important to public health as it is a major contributory factor to collision risk and casualty severity. 20mph (32km/h) speed limit interventions are an increasingly common approach to address this transport and health challenge, but a more developed evidence base is needed to understand their effects. This study describes the changes in traffic speed and traffic volume in the City of Edinburgh, pre- and 12 months post-implementation of phased city-wide 20mph speed limits from 2016–2018. Methods The City of Edinburgh Council collected speed and volume data across one full week (24 hours a day) pre- and post-20mph speed limits for 66 streets. The pre- and post-sp…
Improved GNSS positioning exploiting a vehicular P2P infrastructure
2010
This paper considers the possibility to exploit external altitude measurements to improve the performance of a Kalman based GNSS receiver. The altitude measurements are provided by means of a peer to peer network, that is supposed to be based on the evolution of the 802.11 standard for the vehicular environment, namely the WAVE (802.11p). The performance of such a system are investigated for different characteristics of the aiding measurement and for a different number and disposals of the aiding peers. The aiding measurement is obtained starting from the altitude measurements that the other peers in the network send to the aided user. The experiments highlight the need for a parameter that…
Two-Player Noncooperative Games over a Freight Transportation Network''
2004
A game between two players acting on the same road transportation network is considered in this paper. The first player aims at minimizing the transportation costs, whereas the second player aims at maximizing her profit (or, in general, her utility) that is proportional to the flow passing through the arcs under her control. We introduce bilevel linear programming formulations for this problem. We derive conditions of existence and properties of the equilibrium points and propose an algorithm finding a local optimal solution. Finally, we present an application of the model to a real system involving trucks travelling through Europe from a Middle Eastern country.
Assistive robotic walker parameter identification for estimation of human thrust without force sensors
2017
In this paper we propose a parameter identification procedure for the wheel-motor dynamic of a robotic walker, i.e. a commercial trolley for elderly people endowed with cognitive, sensing and guidance capabilities. The objective of the wheel-motor dynamic model is to generate a suitable time reference to be used in an estimation algorithm. The ultimate goal of the estimation algorithm is to retrieve the thrust, i.e. torque and force, that the older adult user of the robotic walker applies to the platform. These quantities are of paramount importance in order to adopt intelligent and comfortable walker guidance algorithms. The novelty of this approach is the avoidance of additional costly se…
I criteri di determinazione del danno nelle model rules e nel diritto comune europeo
2011
The article describes the many criteria that actually determine recoverable damages in contract, analysing similarities and differences among European legal systems and in Model Rules. In the second part, it identifies shared criteria and verify how they can be translated in a future European contract law.
Acceptance towards digital health interventions – Model validation and further development of the Unified Theory of Acceptance and Use of Technology
2021
Internet- and mobile-based interventions (IMI) offer an effective way to complement health care. Acceptance of IMI, a key facilitator of their implementation in routine care, is often low. Based on the Unified Theory of Acceptance and Use of Technology (UTAUT), this study validates and adapts the UTAUT to digital health care. Following a systematic literature search, 10 UTAUT-grounded original studies (N = 1588) assessing patients' and health professionals' acceptance of IMI for different somatic and mental health conditions were included. All included studies assessed Performance Expectancy, Effort Expectancy, Social Influence, Facilitating Conditions and acceptance as well as age, gender,…
Ecological Sampling Methods for Studying Everyday Situations
2017
This chapter reviews existing and emerging methodologies for the ambulatory assessment of real-world situations. It distinguishes between first-person/subjective and third-person/objective approaches and provides research examples for each reviewed ecological assessment method. The chapter opens with a discussion of why it is important to assess situations directly in daily life. The following two main sections review approaches for (a) the first-person assessment of real-world situation experiences and perceptions, such as experience sampling and daily diary approaches, and (b) the third-person assessment of objective real-world situation cues, such as naturalistic observation and mobile s…