Search results for "Bing"

showing 10 items of 474 documents

Role of mTOR-regulated autophagy in spine pruning defects and memory impairments induced by binge-like ethanol treatment in adolescent mice.

2021

Abstract Adolescence is a brain maturation developmental period during which remodeling and changes in synaptic plasticity and neural connectivity take place in some brain regions. Different mechanism participates in adolescent brain maturation, including autophagy that plays a role in synaptic development and plasticity. Alcohol is a neurotoxic compound and its abuse in adolescence induces neuroinflammation, synaptic and myelin alterations, neural damage and behavioral impairments. Changes in synaptic plasticity and its regulation by mTOR have also been suggested to play a role in the behavioral dysfunction of binge ethanol drinking in adolescence. Therefore, by considering the critical ro…

MaleautophagyDendritic spineSynaptic pruningPeriod (gene)synaptic pruningBiologyPathology and Forensic MedicineBinge Drinkingbinge ethanol treatmentMyelinMicemedicineAnimalsPI3K/AKT/mTOR pathwayNeuroinflammationResearch Articlescognitive functionMemory DisordersNeuronal PlasticityGeneral NeuroscienceTOR Serine-Threonine KinasesAutophagyBraindendritic spinesMice Inbred C57BLmedicine.anatomical_structureSynaptic plasticitymTORFemaleadolescenceNeurology (clinical)NeuroscienceResearch ArticleBrain pathology (Zurich, Switzerland)
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Physical activity, use of alcohol and smoking in middle-aged and aging men. A longitudinal study among Finnish male former athletes and controls

2020

It is not known whether decrease in physical activity (PA) is associated with binge drinking among former athletes. The purpose of this study was to investigate the reciprocal associations between PA and use of alcohol among former athletes and controls at four time points. Furthermore, we examined whether there were longitudinal latent profiles related to use of alcohol, smoking and PA during the follow-up. Finnish male former elite athletes (n = 1633) and matched controls (n = 1099) questionnaire-reported their PA, alcohol consumption and smoking at four time points in 1985, 1995, 2001 and 2008. Former athletes were more physically active and smoked less than controls, but in all profiles…

MaleelintavatLongitudinal studyTime FactorsAlcohol Drinkingformer athlete(s)Physical activityBinge drinking030209 endocrinology & metabolismPhysical Therapy Sports Therapy and RehabilitationAlcoholpitkittäistutkimusBinge Drinking03 medical and health scienceschemistry.chemical_compound0302 clinical medicinetupakointiHumansMedicineOrthopedics and Sports MedicineLongitudinal Studieskohorttitutkimusalkoholi (päihteet)ExerciseFinlandAgedMarital StatusbiologyAthletesbusiness.industrySmoking030229 sport sciencesGeneral MedicineMiddle Agedbiology.organism_classificationchemistryAthletesCase-Control StudiesAthletic Injuriesalkoholinkäyttöbusinessfyysinen aktiivisuusurheilijatFollow-Up StudiesClinical psychologyCohort studyEuropean Journal of Sport Science
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The rewarding effects of ethanol are modulated by binge eating of a high-fat diet during adolescence

2017

Abstract Binge-eating is considered a specific form of overeating characterized by intermittent and high caloric food intake in a short period of time. Epidemiologic studies support a positive relation between the ingestion of fat and ethanol (EtOH), specifically among adolescent subjects. The aim of this work was to clarify the role of the compulsive, limited and intermittent intake of a high-fat food during adolescence on the rewarding effects of EtOH. After binge-eating for 2 h, three days a week from postnatal day (PND) 29, the reinforcing effects of EtOH were tested with EtOH self-administration (SA), conditioned place preference (CPP) and ethanol locomotor sensitization procedures in …

Maleendocrine systemmedicine.medical_specialtyTime FactorsSelf AdministrationNucleus accumbensDiet High-FatMice03 medical and health sciencesCellular and Molecular Neuroscience0302 clinical medicineRewardInternal medicinemental disordersmedicineAnimalsIngestionBulimiaOvereatingreproductive and urinary physiologyPharmacologyEthanolBinge eatingDrug Administration RoutesCentral Nervous System DepressantsConditioned place preference030227 psychiatryVentral tegmental areaDisease Models Animalmedicine.anatomical_structureEndocrinologyAnimals NewbornAnesthesiaConditioning Operantmedicine.symptomμ-opioid receptorSelf-administrationPsychologyLocomotion030217 neurology & neurosurgeryNeuropharmacology
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Periodontal Treatment with an Er:YAG Laser or Scaling and Root Planing. A 2-Year Follow-Up Split-Mouth Study

2003

Non-surgical periodontal treatment with an Er:YAG laser has been shown to result in significant clinical attachment level gain; however, clinical results have not been established on a long-term basis following Er:YAG laser treatment. Therefore, the aim of the present study was to present the 2-year results following non-surgical periodontal treatment with an Er:YAG laser or scaling and root planing.Twenty patients with moderate to advanced periodontal destruction were treated under local anesthesia, and the quadrants were randomly allocated in a split-mouth design to either 1) Er:YAG laser (ERL) using an energy level of 160 mJ/pulse and 10 Hz, or 2) scaling and root planing (SRP) using han…

Malegenetic structuresGingival and periodontal pocketMatched-Pair AnalysisBleeding on probingDental PlaqueDentistryRoot PlaningScaling and root planingPeriodontal Attachment LossmedicineHumansPeriodontal PocketGingival RecessionYttriumPeriodontitisGingival recessionPeriodontitisBacteriabusiness.industryDental Plaque Indexmedicine.diseaseDental Plaque IndexTreatment OutcomeClinical attachment lossDental ScalingPeriodonticsAluminum SilicatesFemaleLaser TherapyPeriodontal Indexmedicine.symptomGingival HemorrhagebusinessEr:YAG laserErbiumFollow-Up StudiesJournal of Periodontology
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The association among interpersonal problems, binge behaviors, and self-esteem, in the assessment of obese individuals

2011

Abstract Objectives Although disordered eating has been assumed to be associated with interpersonal problems, there is a lack of research regarding the relationship between interpersonal problems and obesity. This study explored associations among self-esteem, binge behaviors, and interpersonal problems in obese individuals, by contrasting obese persons with overweight persons, and to investigate whether body mass index (BMI), binge behaviors, and self-esteem predict interpersonal problems in obese individuals. Methods A group of nonobese overweight people (n = 65; BMI range, 25-29.9 kg/m 2 ) and a group of obese people (n = 78; BMI >35 kg/m 2 ) were selected from 224 people attending a men…

Malelcsh:RC435-571Interpersonal communicationOverweightBody Mass IndexInterpersonal relationshipSurveys and Questionnaireslcsh:PsychiatrySettore M-PSI/08 - Psicologia ClinicamedicineBody ImageHumansInterpersonal RelationsObesityDisordered eatingBulimiaobesity interpersonal problems self-esteem binge eating disordermedicine.diseaseObesitySelf ConceptPsychiatry and Mental healthClinical PsychologyEating disordersRegression AnalysisFemalemedicine.symptomBinge Eating ScalePsychologyBody mass indexClinical psychology
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Different versions of the Alcohol Use Disorders Identification Test (AUDIT) as screening instruments for underage binge drinking

2015

BACKGROUND: The changes experienced in recent years in the conceptualization of binge drinking (BD) make it necessary to revise the usefulness of the existing instruments for its detection among minors. The AUDIT and its abbreviated versions have shown their utility in different populations and consumption ranges, but there has been little research into their use in the detection of BD among adolescents. This study tests the capacity of the AUDIT, AUDIT-C and AUDIT-3 to identify BD adolescents, indicating the optimal cut-off points for each sex. METHODS: High school students self-administered the AUDIT and completed a weekly self-report of their alcohol intake. BD is classified into differe…

Malemedicine.medical_specialtyAdolescentAlcohol DrinkingPoison controlBinge drinkingUnderage DrinkingAuditToxicologyOccupational safety and healthBinge Drinking03 medical and health sciences0302 clinical medicineSurveys and Questionnaireshealth services administrationInjury preventionmedicineHumansPharmacology (medical)030212 general & internal medicineStudentsPsychiatryPharmacologyAlcohol Use Disorders Identification Testbusiness.industryHuman factors and ergonomicsmedicine.diseaseSubstance abuseAlcoholismPsychiatry and Mental healthFemaleSelf Reportbusiness030217 neurology & neurosurgeryDrug and Alcohol Dependence
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Binge ethanol drinking during adolescence modifies cocaine responses in mice

2016

Binge ethanol drinking is an emerging pattern of excessive consumption among adolescents and young adults. Repeated ethanol intoxication has negative consequences during critical periods of brain development. Therefore, binge ethanol intake represents a vulnerability factor that promotes subsequent manifestations of neuropsychiatric disorders. In this study, we investigated the effects of oral binge ethanol intake during adolescence on the subsequent effects of cocaine in C57BL/6 mice. Firstly, we evaluated the oral ethanol intake of two binge ethanol procedures with different ethanol concentrations (20% v/v versus 30%, v/v). The highest ethanol intake was found in mice exposed to the lowe…

Malemedicine.medical_specialtyAlcohol DrinkingBinge drinkingSelf AdministrationBehavioural sensitizationBinge DrinkingMice03 medical and health scienceschemistry.chemical_compound0302 clinical medicineCocaineInternal medicinemedicineBinge ethanolAnimalsPharmacology (medical)Young adultPharmacologyEthanolBehavior AnimalEthanolbusiness.industryAge Factors3. Good health030227 psychiatryMice Inbred C57BLPsychiatry and Mental healthEndocrinologychemistryEthanol intakeEthanol intoxicationSelf-administrationbusinessLocomotion030217 neurology & neurosurgeryJournal of Psychopharmacology
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Adolescent binge‐ethanol accelerates cognitive impairment and β‐amyloid production and dysregulates endocannabinoid signaling in the hippocampus of A…

2019

Previous research in rodents suggests that the long‐term neurobehavioral disturbances induced by chronic ethanol (EtOH) exposure could be due to endocannabinoid system (ECS) alterations. Moreover, ECS failure has been proposed to mediate the cognitive impairment and β‐amyloid production in Alzheimer disease (AD). Thus, in the present study, we evaluated the effects of adolescent EtOH binge drinking on the cognitive disturbances, hippocampal β‐amyloid levels, and in the ECS expression on a transgenic mouse model (APP/PSEN, AZ) of AD. We exposed AZ and wild‐type mice to a binge‐drinking treatment during adolescence. At 6 and 12 months of age, we evaluated hippocampal‐dependent learning and me…

Malemedicine.medical_specialtyDiacylglycerol lipasehippocampusmedicine.medical_treatmentMedicine (miscellaneous)HippocampusMice TransgenicHippocampusBinge DrinkingMice03 medical and health sciences0302 clinical medicineAlzheimer DiseaseInternal medicinemental disordersGene expressionmedicineAnimalsCognitive DysfunctionPharmacologyAmyloid beta-PeptidesEthanolbiologyWild typeendocannabinoidmedicine.diseaseEndocannabinoid systembinge drinkingMonoacylglycerol Lipases030227 psychiatryMonoacylglycerol lipaseDisease Models AnimalPsychiatry and Mental healthEndocrinologybiology.proteinβ‐amyloidadolescenceFemaleCannabinoidAlzheimer diseaseAlzheimer's disease030217 neurology & neurosurgeryEndocannabinoidsSignal TransductionAddiction Biology
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Emotional eating scale for children and adolescents: psychometric characteristics in a Spanish sample

2011

The aims of this study were to validate the Emotional Eating Scale version for children (EES-C) in a Spanish population and study the differences in emotional eating among children with binge eating (BE), overeating (OE), and no episodes of disordered eating (NED). The questionnaire was completed by 199 children aged 9 to 16 years. Confirmatory factor analysis revealed five scales: eating in response to anger, anxiety, restlessness, helplessness, and depression. The EES-C showed good internal consistency and test-retest reliability, and it showed moderate relationships with measures of disordered-eating [Children's Eating Attitudes Test-26 (ChEAT-26), Questionnaire of Eating and Weight Patt…

Malemedicine.medical_specialtyEmotional eatingAdolescentPsychometricsEmotionsHyperphagiaFeeding and Eating DisordersBinge-eating disorderBinge eating disorderSurveys and QuestionnairesDevelopmental and Educational PsychologymedicineHumansBulimiaDisordered eatingOvereatingChildPsychiatryChild Behavior ChecklistLoss of controlPsychiatric Status Rating ScalesPsychological TestsBinge eatingChildren psychopathologydigestive oral and skin physiologyInfants--Alimentació--Aspectes psicològicsReproducibility of ResultsFeeding BehaviorEmotional eatingmedicine.diseaseClinical PsychologyEating disordersPsychometric propertiesSpainAnxietyFemalemedicine.symptomFactor Analysis StatisticalPsychologyChildren--Nutrition--Psychological aspects
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Assessment of impairments that limit exercise and use of impairment information to generate an exercise.

2007

Prescribing the correct exercise program is a challenge for older adults with multiple physiological impairments. The authors evaluated an assessment instrument that incorporates results of multiple categories of impairment, including strength, balance, gait, vision, and cognitive function. The physical therapist made judgments on the relative impact of 9 different impairments on specific exercises and on the total impact of all impairments on particular exercises. In a cohort age 75–85 y, functional limitations, impaired balance, pain, and low physical endurance were estimated to have the largest impact on the ability to carry out exercise activities, primarily walking, stair climbing, bal…

Malemedicine.medical_specialtyFrail ElderlyPhysical Therapy Sports Therapy and RehabilitationSeverity of Illness IndexPhysical medicine and rehabilitationSeverity of illnessPostural BalancemedicineHumansDisabled PersonsLongitudinal StudiesMusculoskeletal DiseasesMobility LimitationExerciseGeriatric AssessmentPostural BalancePhysical Therapy ModalitiesBalance (ability)AgedPain MeasurementAged 80 and overAnalysis of VarianceImpaired BalanceStair climbingRehabilitationCognitionGaitHealth SurveysCohortChronic DiseaseDistrict of ColumbiaPhysical therapyFemaleGeriatrics and GerontologyPsychologyhuman activitiesGerontologyJournal of aging and physical activity
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