Search results for "Binge"

Early Response to treatment in Eating Disorders: A Systematic Review and a Diagnostic Test Accuracy Meta-Analysis

2016

Objective Early response to eating disorders treatment is thought to predict a later favourable outcome. A systematic review of the literature and meta-analyses examined the robustness of this concept. Method The criteria used across studies to define early response were summarised following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Diagnostic Test Accuracy methodology was used to estimate the size of the effect. Results Findings from 24 studies were synthesized and data from 14 studies were included in the meta-analysis. In Anorexia Nervosa, the odds ratio of early response predicting remission was 4.85(95%CI: 2.94–8.01) and the summary Area Under t…

No Association Between the Dopamine D2 Receptor Taq I A1 Allele and Earlier Age of Onset of Alcohol Dependence According to Different Specified Crite…

2001

BACKGROUND: The presence of the A1 allele of the dopamine D2 receptor TaqI restriction fragment length polymorphism has been reported to be associated with an earlier age of onset of alcohol dependence as a marker for severity. METHODS: We tested this hypothesis with special regard to the definition of the age of onset of alcoholism in 243 patients with alcohol dependence, according to DSM-IV criteria assessed by the standardized interview Munchner Composite International Diagnostic Interview (M-CIDI), consecutively admitted for detoxification. Additionally, the Addiction Severity Index (ASI) was performed. The TaqIA polymorphism was amplified by polymerase chain reaction (PCR), and the PCR…

Prospective associations between alcohol use, binge drinking and sexual activity in older adults: The English Longitudinal Study of Ageing

2021

The present study aimed to investigate associations between alcohol consumption, including binge drinking, and sexual activity. Data were from 1,622 men and 2,195 women aged ≥50 years participating in the English Longitudinal Study of Ageing. Multivariable logistic regression was used to prospectively assess sex-specific associations between baseline frequency of alcohol use in the last year or binge drinking in the last week (self-reported in 2004/05) and sexual activity at 8-year follow-up (2012/13). Covariates included partner status, age, ethnicity, wealth, limiting long-standing illness, smoking status, physical activity, and depressive symptoms. After adjustment, regular alcohol consu…

Consequences and comorbidities associated with obesity

2017

This chapter reviews the importance of diabetes as a major complication of obesity, starting with examining the epidemiological relationship between diabetes and obesity. It is clear from the epidemiological data reported that obesity is strongly associated with onset and, in particular, the premature onset, of type 2 diabetes. However, in established heart disease and heart failure, obesity is associated with lower mortality. The chapter considers the epidemiological evidence linking adiposity with the development of cancer, and describes the proposed mechanisms by which excess body fat may impact on cancer risk. The global prevalence of osteoarthritis continues to rise, both because of an…

Parental Monitoring and Youth's Binge Behaviors: The Role of Sensation Seeking and Life Satisfaction

2019

Framed within an ecological perspective of the onset of adolescent problem behaviors, the current study explored the joint role of parent-adolescents’ relationships and youth's individual factors in binge eating and drinking. Firstly, in line with pieces of research highlighting the beneficial impact of effective parenting on youth development, the present paper sought to enhance the knowledge about the positive influence of parental monitoring on youth's binge drinking and eating. Moreover, since literature evidenced that the explanatory mechanisms of the association between parental monitoring and binge behaviors are not fully explored, the study focused on the potential intervening role …

The role of depression and impulsivity in the psychopathology of bulimia nervosa.

2013

Introduction: The study aimed to analyze the role of depression and impulsivity in the psychopathology of bulimia nervosa (BN). Materials and methods: Seventy female patients with DSM-IV BN, purging subtype, were assessed for eating-related symptoms, body dissatisfaction, affective symptoms, impulsivity, and personality traits. Factor analysis and structural equation modeling methods were used for statistical analysis. Results: BN appeared as a condition which incorporated 5 general dimensions: a) binge eating and compensatory behaviours; b) restrictive eating; c) body dissatisfaction; d) dissocial personality traits; and e) a cluster of features which was called "emotional instability" The…

Role of neuroinflammation in ethanol neurotoxicity

2019

Abstract Alcohol is a neurotoxic compound whose abuse can cause alterations in brain structure and functions, although these effects are more dramatic while the brain develops. The molecular mechanisms of neurotoxic effects of alcohol are complex and remain largely unknown. Current evidence from human and animal studies supports the role of the neuroimmune system in many actions of ethanol on the central nervous system, including neurotoxicity. Different studies have shown that, by activating innate immune receptors TLRs (Toll-like receptors) and (NOD)-like receptors (inflammasome NLRs) in glial cells, alcohol triggers signaling pathways which culminate in the production of pro-inflammatory…

Interpersonal difficulties in obesity: A systematic review and meta-analysis to inform a rejection sensitivity-based model

2019

Abstract Obesity is associated with difficulties due to stigma and loneliness. These impact negatively on individuals’ quality of life and behaviour change efforts. Increased sensitivity to others’ negative feedback might play a role in the maintenance of these difficulties and could be addressed in psychological interventions. We conducted a systematic review of interpersonal difficulties in individuals with obesity, across the lifespan. We investigated early interpersonal adversity (i.e. frequency of teasing/bullying), perceived interpersonal stress and quality of social life, based on a rejection sensitivity model. The databases PubMed, Web of Knowledge and AGRIS, Embase, Medline and Psy…

Relazioni interpersonali, stati emotivi e autostima in soggetti obesi binge eaters

2009

Housing conditions modulate the reinforcing properties of cocaine in adolescent mice that binge on fat

2017

Abstract Binge eating is a specific form of overeating characterized by intermittent, excessive eating. To date, several studies have addressed the effects that bingeing on fat has on the rewarding effects of drugs of abuse, but they have found contradictory and highly variable results. Housing conditions could modulate these results, as most studies employ isolated animals to measure the exact amount of food that is ingested. The aim of this study was to evaluate the effects of housing conditions on the response of mice to cocaine, modulated by bingeing on a high-fat diet during adolescence. After 40 days of binge-eating for 2 h, three days a week (PND 29–69), the reinforcing effects of a …