Search results for "Bio-nanocomposite"

showing 3 items of 3 documents

Halloysite nanotubes for efficient loading, stabilization and controlled release of insulin

2018

Hypothesis: Oral insulin administration is not actually effective due to insulin rapid degradation, inactivation and digestion by proteolytic enzymes which results in low bioavailability. Moreover insulin is poorly permeable and lack of lipophilicity. These limits can be overcome by the loading of protein in some nanostructured carrier such as halloysite nanotubes (HNTs). Experiments: Herein we propose an easy strategy to obtain HNT hybrid materials for the delivery of insulin. We report a detailed description on the thermal behavior and stability of insulin loaded and released from the HNTs hybrid by the combination of several techniques. Findings: Release experiments of insulin from the H…

Dichroismmedicine.medical_treatmentHalloysite nanotube02 engineering and technology01 natural sciencesBiochemistryNanocompositesChitosanchemistry.chemical_compoundColloid and Surface ChemistryDrug StabilityProtein stabilityHalloysite nanotube (HNTs)InsulinTransdermalSettore CHIM/02 - Chimica FisicaDrug CarriersNanotubesProteolytic enzymes021001 nanoscience & nanotechnologyControlled releaseSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsEnzyme inhibitionAluminum SilicatesBionanocomposite film0210 nano-technologyHybrid materialBionanocomposite hybridSurface PropertiesDrug Compoundingengineering.materialCircular dichroism data010402 general chemistrySustained release InsulinAdministration CutaneousHalloysiteBiomaterialsKaolinitemedicineParticle SizeHybrid materialChitosanInsulinBiomedical applicationMedical applicationYarn Bio-nanocompositeMembranes Artificial0104 chemical sciencesNanotubeDrug LiberationHalloysite nanotubes Insulin Protein stability Sustained release Bionanocomposite hybridchemistryChemical engineeringDelayed-Action PreparationsengineeringClayNanocarriersSustained release
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Filling of Mater-Bi with Nanoclays to Enhance the Biofilm Rigidity

2018

We investigated the efficacy of several nanoclays (halloysite, sepiolite and laponite) as nanofillers for Mater-Bi, which is a commercial bioplastic extensively used within food packaging applications. The preparation of Mater-Bi/nanoclay nanocomposite films was easily achieved by means of the solvent casting method from dichloroethane. The prepared bio-nanocomposites were characterized by dynamic mechanical analysis (DMA) in order to explore the effect of the addition of the nanoclays on the mechanical behavior of the Mater-Bi-based films. Tensile tests found that filling Mater-Bi with halloysite induced the most significant improvement of the mechanical performances under traction force, …

Materials sciencelcsh:BiotechnologyBiomedical Engineering02 engineering and technologyengineering.material010402 general chemistry01 natural sciencesHalloysiteMater-BiBiomaterialsCoatinglcsh:TP248.13-248.65Ultimate tensile strengthhalloysiteComposite materialElastic moduluschemistry.chemical_classificationlcsh:R5-920NanocompositeCommunicationPolymerDynamic mechanical analysis021001 nanoscience & nanotechnologymechanical performance0104 chemical scienceslaponitebio-nanocompositeschemistrysepioliteNanoclayengineeringlcsh:Medicine (General)0210 nano-technologyGlass transitionBio-nanocompositenanoclaysJournal of Functional Biomaterials
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Functional Bionanocomposite Fibers of Chitosan Filled with Cellulose Nanofibers Obtained by Gel Spinning

2021

Extremely high mechanical performance spun bionanocomposite fibers of chitosan (CHI), and cellulose nanofibers (CNFs) were successfully achieved by gel spinning of CHI aqueous viscous formulations filled with CNFs. The microstructural characterization of the fibers by X-ray diffraction revealed the crystallization of the CHI polymer chains into anhydrous chitosan allomorph. The spinning process combining acidic–basic–neutralization–stretching–drying steps allowed obtaining CHI/CNF composite fibers of high crystallinity, with enhanced effect at incorporating the CNFs. Chitosan crystallization seems to be promoted by the presence of cellulose nanofibers, serving as nucleation sites for the gr…

polymer fiber yarnsMaterials sciencePolymers and PlasticsComposite numberOrganic chemistrymechanical propertiesArticlelaw.inventionChitosanchemistry.chemical_compoundCrystallinityQD241-441lawFiberComposite materialCrystallizationCellulosecellulose nanofiberschemistry.chemical_classificationGeneral ChemistryPolymerchemistrybio-nanocompositesgel/wet spinningNanofiberchitosanPolymers
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