Search results for "Biochem"

showing 10 items of 20937 documents

Role of Bacillus thuringiensis Cry1A toxins domains in the binding to the ABCC2 receptor from Spodoptera exigua

2018

Abstract Cry proteins from Bacillus thuringiensis (Bt) have been used to control insect pests either as formulated sprays or as in Bt-crops. However, field-evolved resistance to Bt proteins is threatening the long-term use of Bt products. The SeABCC2 locus has been genetically linked to resistance to a Bt bioinsecticide (Xentari™) in Spodoptera exigua (a mutation producing a truncated form of the transporter lacking an ATP binding domain was found in the resistant insects). Here, we investigated the role of SeABCC2 in the mode of action of Cry1Aa, Cry1Ab, Cry1Ac, Cry1Ca, and two Cry1A-1Ca hybrids by expressing the receptor in Sf21 and HEK293T cell lines. Cell toxicity assays showed that Sf2…

0106 biological sciences0301 basic medicineCell SurvivalBacillus thuringiensisGene ExpressionSpodopteraSpodopteraTransfection01 natural sciencesBiochemistryHemolysin ProteinsStructure-Activity Relationship03 medical and health sciencesBacterial ProteinsProtein DomainsBacillus thuringiensisExiguaSf9 CellsAnimalsHumansProtein IsoformsBinding siteReceptorMolecular BiologySf21Binding SitesBacillus thuringiensis Toxinsbiologyfungibiology.organism_classificationMultidrug Resistance-Associated Protein 2Recombinant ProteinsClone CellsEndotoxins010602 entomologyHEK293 Cells030104 developmental biologyBiochemistryCry1AcLarvaInsect ScienceMutationInsect ProteinsMultidrug Resistance-Associated ProteinsPlasmidsProtein BindingBinding domainInsect Biochemistry and Molecular Biology
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A non-venomous sPLA2 of a lepidopteran insect: Its physiological functions in development and immunity

2018

Eicosanoids are oxygenated C20 polyunsaturated fatty acids that mediate various physiological processes in insects. Eicosanoid biosynthesis begins with a C20 precursor, arachidonic acid (5,8,11,14-eicosatetraenoic acid: AA). AA is usually released from phospholipids at sn-2 position by catalytic activity of phospholipase A2 (PLA2). Although various PLA2s classified into 16 gene families (= Groups) are known in various biological systems, few PLA2s are known in insects. Only two PLA2s involved in intracellular calcium independent PLA2 (iPLA2) group have been identified in lepidopteran insects with well known eicosanoid physiology. This study reports the first secretory PLA2 (sPLA2) in lepido…

0106 biological sciences0301 basic medicineCellular immunitybiologyfungiImmunologySpodopterabiology.organism_classification01 natural sciences010602 entomology03 medical and health sciencesOpen reading framechemistry.chemical_compound030104 developmental biologyPhospholipase A2BiochemistrychemistryJuvenile hormoneExiguabiology.proteinlipids (amino acids peptides and proteins)Arachidonic acidPeptide sequenceDevelopmental BiologyDevelopmental & Comparative Immunology
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Melatonin in the seasonal response of the aphid Acyrthosiphon pisum.

2018

Aphids display life cycles largely determined by the photoperiod. During the warm long-day seasons, most aphid species reproduce by viviparous parthenogenesis. The shortening of the photoperiod in autumn induces a switch to sexual reproduction. Males and sexual females mate to produce overwintering resistant eggs. In addition to this full life cycle (holocycle), there are anholocyclic lineages that do not respond to changes in photoperiod and reproduce continuously by parthenogenesis. The molecular or hormonal events that trigger the seasonal response (i.e., induction of the sexual phenotypes) are still unknown. Although circadian synthesis of melatonin is known to play a key role in verteb…

0106 biological sciences0301 basic medicineCentral Nervous SystemMaleendocrine systemAANATPhotoperiodCircadian clockZoology01 natural sciencesArylalkylamine N-AcetyltransferaseGeneral Biochemistry Genetics and Molecular BiologyMelatonin03 medical and health sciencesmedicineAnimalsCircadian rhythmEcology Evolution Behavior and SystematicsMelatoninphotoperiodismAphidbiologyfood and beveragesbiology.organism_classificationAcyrthosiphon pisumSexual reproduction010602 entomology030104 developmental biologyInsect ScienceAphidsFemaleSeasonsAgronomy and Crop Sciencehormones hormone substitutes and hormone antagonistsmedicine.drugInsect scienceReferences
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How water-soluble chlorophyll protein extracts chlorophyll from membranes.

2020

Water-soluble chlorophyll proteins (WSCPs) found in Brassicaceae are non-photosynthetic proteins that bind only a small number of chlorophylls. Their biological function remains unclear, but recent data indicate that WSCPs are involved in stress response and pathogen defense as producers of reactive oxygen species and/or Chl-regulated protease inhibitors. For those functions, WSCP apoprotein supposedly binds Chl to become physiologically active or inactive, respectively. Thus, Chl-binding seems to be a pivotal step for the biological function of WSCP. WSCP can extract Chl from the thylakoid membrane but little is known about the mechanism of how Chl is sequestered from the membrane into the…

0106 biological sciences0301 basic medicineChlorophyllCircular dichroismHot Temperaturemedicine.medical_treatmentBiophysicsmacromolecular substances01 natural sciencesBiochemistryLepidiumThylakoids03 medical and health scienceschemistry.chemical_compoundpolycyclic compoundsmedicineBinding sitePlant Proteinschemistry.chemical_classificationReactive oxygen speciesProteasefood and beveragesMembrane ProteinsWaterCell BiologyAmino acid030104 developmental biologyMembraneBiochemistrychemistrySolubilityThylakoidChlorophyll010606 plant biology & botanyBiochimica et biophysica acta. Biomembranes
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In vivo photoprotection mechanisms observed from leaf spectral absorbance changes showing VIS–NIR slow-induced conformational pigment bed changes

2019

Abstract Regulated heat dissipation under excessive light comprises a complexity of mechanisms, whereby the supramolecular light-harvesting pigment–protein complex (LHC) shifts state from light harvesting towards heat dissipation, quenching the excess of photo-induced excitation energy in a non-photochemical way. Based on whole-leaf spectroscopy measuring upward and downward spectral radiance fluxes, we studied spectrally contiguous (hyperspectral) transient time series of absorbance A(λ,t) and passively induced chlorophyll fluorescence F(λ,t) dynamics of intact leaves in the visible and near-infrared wavelengths (VIS–NIR, 400–800 nm) after sudden strong natural-like illumination exposure. …

0106 biological sciences0301 basic medicineChlorophyllMaterials sciencePassive chlorophyll a fluorescencePigment–protein dynamicsLightHyperspectral remote sensingAnalytical chemistryJuglansPlant Science01 natural sciencesBiochemistryEnergy quenchingFluorescenceAbsorbance03 medical and health sciencesTransmittanceFiber Optic TechnologySpectroscopyChlorophyll fluorescencechemistry.chemical_classificationSpectroscopy Near-InfraredAbsorbed photosynthetic active radiation (APAR)Non-photochemical quenching (NPQ)Cell BiologyGeneral MedicineEquipment DesignPigments BiologicalPhotochemical ProcessesCarotenoidsPlant LeavesWavelength030104 developmental biologychemistryXanthophyllRadianceOriginal ArticleAbsorbance shiftMorusControlled heat dissipation010606 plant biology & botanyPhotosynthesis Research
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Comparative Mitogenomics of Leeches (Annelida: Clitellata): Genome Conservation and Placobdella-Specific trnD Gene Duplication.

2015

Mitochondrial DNA sequences, often in combination with nuclear markers and morphological data, are frequently used to unravel the phylogenetic relationships, population dynamics and biogeographic histories of a plethora of organisms. The information provided by examining complete mitochondrial genomes also enables investigation of other evolutionary events such as gene rearrangements, gene duplication and gene loss. Despite efforts to generate information to represent most of the currently recognized groups, some taxa are underrepresented in mitochondrial genomic databases. One such group is leeches (Annelida: Hirudinea: Clitellata). Herein, we expand our knowledge concerning leech mitochon…

0106 biological sciences0301 basic medicineClitellatalcsh:MedicineBiochemistry01 natural sciencesGenomeDatabase and Informatics MethodsRNA TransferGene DuplicationGene OrderInvertebrate GenomicsGene duplicationAnnelidslcsh:SciencePhylogenyEnergy-Producing OrganellesData ManagementGeneticseducation.field_of_studyMultidisciplinaryPhylogenetic treePhylogenetic AnalysisGenomicsGenomic DatabasesMitochondriaNucleic acidsPhylogeneticsGenes MitochondrialPlacobdella parasiticaCellular Structures and OrganellesTransfer RNAResearch ArticleComputer and Information SciencesMitochondrial DNAPopulationBioenergeticsBiologyResearch and Analysis Methods010603 evolutionary biologyEvolution MolecularOpen Reading Frames03 medical and health sciencesPhylogeneticsLeechesGeneticsAnimalsEvolutionary Systematics14. Life underwaterCodonMolecular Biology TechniquesNon-coding RNAeducationMolecular BiologyTaxonomyMolecular Biology Assays and Analysis TechniquesEvolutionary Biologylcsh:ROrganismsBiology and Life SciencesComputational BiologyCell BiologyGenome Analysisbiology.organism_classificationInvertebratesBiological Databases030104 developmental biologyAnimal GenomicsGenome MitochondrialRNAlcsh:QPLoS ONE
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How to fight multiple enemies : target-specific chemical defences in an aposematic moth

2017

Animals have evolved different defensive strategies to survive predation, among which chemical defences are particularly widespread and diverse. Here we investigate the function of chemical defence diversity, hypothesizing that such diversity has evolved as a response to multiple enemies. The aposematic wood tiger moth (Arctia plantaginis) displays conspicuous hindwing coloration and secretes distinct defensive fluids from its thoracic glands and abdomen. We presented the two defensive fluids from laboratory-reared moths to two biologically relevant predators, birds and ants, and measured their reaction in controlled bioassays (no information on colour was provided). We found that defensive…

0106 biological sciences0301 basic medicineColorAposematismBiologyMoths010603 evolutionary biology01 natural sciencesGeneral Biochemistry Genetics and Molecular BiologyPredationBirds03 medical and health sciencesSpecies SpecificityAnimalsaposematismta116General Environmental ScienceGeneral Immunology and MicrobiologyEcologyEcologyAntsfungipredator–prey interactionschemical defencesGeneral MedicinepyrazinesBiological EvolutionBody Fluids030104 developmental biologyPredatory Behaviorta1181General Agricultural and Biological SciencesProceedings of the Royal Society B : Biological Sciences
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Spatio-temporal dynamics of genetic variation in the Iberian lynx along its path to extinction reconstructed with ancient DNA

2017

here is the tendency to assume that endangered species have been both genetically and demographically healthier in the past, so that any genetic erosion observed today was caused by their recent decline. The Iberian lynx (Lynx pardinus) suffered a dramatic and continuous decline during the 20th century, and now shows extremely low genome- and species-wide genetic diversity among other signs of genomic erosion. We analyze ancient (N = 10), historical (N = 245), and contemporary (N = 172) samples with microsatellite and mitogenome data to reconstruct the species' demography and investigate patterns of genetic variation across space and time. Iberian lynx populations transitioned from low but …

0106 biological sciences0301 basic medicineConservation of Natural ResourcesMetapopulationBiologyLincesExtinction Biological010603 evolutionary biology01 natural sciencesEndangered speciesgenetic erosion03 medical and health sciencesGenetic driftGenetic variationGeneticsAnimalsDNA AncientGenetic erosionancient DNAMolecular BiologyQH426Institut für Biochemie und BiologieDiscoveriesEcology Evolution Behavior and SystematicsPaleobiologíaGenetic diversityQLGenomeExtinctionAncient DNAEcologyQHEndangered SpeciesGenetic DriftGenetic VariationPaleogeneticsParque nacional de DoñanaSequence Analysis DNAIberian lynxGenéticahumanities030104 developmental biologyAncient DNAGenome MitochondrialLynxPaleogeneticsGenetic erosionpaleogeneticsMicrosatellite Repeats
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Algae in Biotechnological Processes

2018

As photoautotrophic organisms, algae possess all of the valuable features that determine their role as the primary producers in the biosphere. A wide range of tolerance based on their extremely efficient adaptation to biochemical processes, as well as the specific cellular structure of these organisms, when correlated with the ecological plasticity of microalgae in particular, predispose these biota to growing and developing under either laboratory or industrial conditions. Hence, the natural features of algae have opened wide the door for the multidirectional biotechnological use of these organisms, with a dynamically growing number of such applications fully supporting this thesis. Among …

0106 biological sciences0301 basic medicineCyanobacteriaPollutantbiologyPrimary producersPhycobiliproteinBiomassBiotabiology.organism_classification01 natural sciences03 medical and health sciences030104 developmental biologyAlgae010608 biotechnologyEcosystemBiochemical engineering
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Responsiveness of metallothionein and hemocyanin genes to cadmium and copper exposure in the garden snail Cornu aspersum.

2020

Abstract Terrestrial gastropods express metal‐selective metallothioneins (MTs) by which they handle metal ions such as Zn2+, Cd2+, and Cu+/Cu2+ through separate metabolic pathways. At the same time, they depend on the availability of sufficient amounts of Cu as an essential constituent of their respiratory protein, hemocyanin (Hc). It was, therefore, suggested that in snails Cu‐dependent MT and Hc pathways might be metabolically connected. In fact, the Cu‐specific snail MT (CuMT) is exclusively expressed in rhogocytes, a particular molluscan cell type present in the hemocoel and connective tissues. Snail rhogocytes are also the sites of Hc synthesis. In the present study, possible interacti…

0106 biological sciences0301 basic medicineDNA ComplementaryPhysiologymedicine.medical_treatmentSnailsGastropodaSnailBiology010603 evolutionary biology01 natural sciences03 medical and health sciencesstressbiology.animalGastropodaparasitic diseasesGeneticsmedicineMetallothioneinAnimalsMolecular BiologyEcology Evolution Behavior and SystematicsMetal metabolismBase Sequencefungimetal metabolismMidgutHemocyaninbiology.organism_classificationResearch PapersRespiratory protein030104 developmental biologybioaccumulationBiochemistryGene Expression RegulationMetalsHemocyaninsAnimal Science and ZoologyMetallothioneinCornu aspersumCopperrespirationCadmiumResearch PaperJournal of experimental zoology. Part A, Ecological and integrative physiology
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