Search results for "Biome"

showing 10 items of 4164 documents

The interplay between the host microbiome and pathogenic viral infections

2021

The microorganisms associated with an organism, the microbiome, have a strong and wide impact in their host biology. In particular, the microbiome modulates both the host defense responses and immunity, thus influencing the fate of infections by pathogens. Indeed, this immune modulation and/or interaction with pathogenic viruses can be essential to define the outcome of viral infections. Understanding the interplay between the microbiome and pathogenic viruses opens future venues to fight viral infections and enhance the efficacy of antiviral therapies. An increasing number of researchers are focusing on microbiome-virus interactions, studying diverse combinations of microbial communities, …

virusesBiologyBacterial Physiological PhenomenaMicrobiologyViral infectionhost-microbiome interactionsInterferonImmunityVirologymedicineAnimalsHumansMicrobiomeOrganismhost-virus interactionsimmune modulationBacteriaHost (biology)pathogenesisMicrobiotainterferonImmune modulationQR1-502antiviral treatmentsVirus DiseasesImmunologyVirusesMicrobial InteractionsMinireviewmedicine.drugVirus Physiological Phenomena
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Single-chain antibodies against a plant viral RNA-dependent RNA polymerase confer virus resistance.

2004

Crop loss due to viral diseases is still a major problem for agriculture today. We present a strategy to achieve virus resistance based on the expression of single-chain Fv fragments (scFvs) against a conserved domain in a plant viral RNA-dependent RNA polymerase (RdRp), a key enzyme in virus replication. The selected scFvs inhibited complementary RNA synthesis of different plant virus RdRps in vitro and virus replication in planta. Moreover, the scFvs also bound to the RdRp of the distantly related hepatitis C virus. T(1) and T(2) progeny of transgenic lines of Nicotiana benthamiana expressing different scFvs either in the cytosol or in the endoplasmic reticulum showed varying degrees of r…

virusesHepatitis C virusAmino Acid MotifsBiomedical EngineeringNicotiana benthamianaBioengineeringmedicine.disease_causeAntibodies ViralVirus ReplicationApplied Microbiology and BiotechnologyVirusPlant VirusesTombusviruschemistry.chemical_compoundRNA polymerasePlant virusTobaccomedicinePlant DiseasesGeneticsbiologyfungifood and beveragesbiology.organism_classificationPlants Genetically ModifiedRNA-Dependent RNA PolymeraseVirologyTombusviridaechemistryViral replicationMolecular MedicineSingle-Chain AntibodiesBiotechnologyNature biotechnology
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Inertiaalianturit juoksun biomekaniikan tutkimisessa - vertailu perinteisiin analysointimenetelmiin

2013

Juoksutekniikan analysoimisessa käytetään usein liikeanalyysiä ja voimalevyjä, joiden avulla voidaan saada tarkkaa tietoa juoksun biomekaniikasta. Viime aikoina on kuitenkin kehitelty myös uusia laitteita, joilla juoksutekniikan analysoiminen onnistuu harjoitusolosuhteissa helposti. Yksi tälläinen laite on Runteq Oy:n kehittämä RunLab™-laite, joka antaa palautetta juoksutekniikasta perustuen inertiaaliantureihin. Tämän tutkimuksen tarkoituksena oli validoida RunLab™- laite juoksun vertikaalisen liikkeen, tukiajan ja nopeuden hidastumisen kontaktin aikana mittaamisessa. Biomekaanisia muuttujia mitattiin voimalevyjä, 3D- liikeanalyysiä sekä RunLab™-laittetta käyttäen. Tutkimuksessa oli aktiiv…

voimalevytkestävyysjuoksujuoksun biomekaniikkainertiaalianturitliikeanalyysibiomekaniikkajuoksu
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Palautteenantojärjestelmä mäkihypyssä

2011

Malinen, Jukka. 2011. Palautteenantojärjestelmä mäkihypyssä. Biomekaniikan pro gradu -tutkielma. Liikuntabiologian laitos. Jyväskylän yliopisto. 40 s. Mäkihypyssä palautteenanto on tavallisesti perustunut valmentajan kokemukseen analysoida suoritus silmämääräisesti hypyn aikana ja/tai jälkeenpäin videokuvasta. Urheilijoiden saama palaute on siis voinut vaihdella valmentajasta riippuen. Tästä lähtökohdasta haluttiin faktatietoon perustuva palautteenanto valmennukseen. Tämän tutkimuksen tarkoituksena oli suunnitella ja toteuttaa mäkihypyn valmennustilanteen palautteenantojärjestelmä, sijoittaa se Vuokatin HS100 hyppyrimäkeen ja testata sen toimivuus. Lisäksi valmista järjestelmää hyväksi käyt…

voimantuottomäkihyppybiomekaniikkapalautteenanto
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Highly sensitive olfactory biosensors for the detection of volatile organic compounds by surface plasmon resonance imaging

2018

International audience; Nowadays, monitoring of volatile organic compounds (VOCs) is very important in various domains. In this work, we aimed to develop sensitive olfactory biosensors using odorant binding proteins (OBPs) as sensing materials. Three rat OBP3 derivatives with customized binding properties were designed and immobilized on the same chip for the detection of VOCs in solution by surface plasmon resonance imaging (SPRi). We demonstrated that the proteins kept their binding properties after the immobilization under optimized conditions. The obtained olfactory biosensors exhibited very low limits of detection in both concentration (200pM of beta-ionone) and in molecular weight of …

volatile organic compoundConformational change[SDV.BIO]Life Sciences [q-bio]/BiotechnologyOdorant bindingBiomedical EngineeringBiophysicsBiosensing Techniques02 engineering and technologyReceptors Odorant01 natural sciencesHexanal[SPI]Engineering Sciences [physics]chemistry.chemical_compoundElectrochemistryAnimalsVolatile organic compoundComputingMilieux_MISCELLANEOUSDetection limitchemistry.chemical_classificationVolatile Organic CompoundsChromatographyChemistry010401 analytical chemistryGeneral MedicineRepeatabilitySurface Plasmon Resonance021001 nanoscience & nanotechnologyRats0104 chemical sciencesSmellsurface plasmon resonance imagingofactory biosensor0210 nano-technologySelectivityBiosensorodorant binding proteinsBiotechnologyBiosensors and Bioelectronics
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Force transmission and interactions between synergistic muscles

2023

The classical view of muscles as independent motors has been challenged over the past decades. An alternative view has emerged in which muscles are not isolated but embedded in a three-dimensional connective tissue network that links them to adjacent muscles and other non-muscular structures in the body. Animal studies showing that the forces measured at the distal and proximal ends of a muscle are not equal have provided undisputable evidence that these connective tissue linkages are strong enough to serve as an extra pathway for muscular force transmission. In this historical review, we first introduce the terminology and anatomy related to these pathways of muscle force transmission and …

vuorovaikutusMuscle mechanicsRehabilitationBiomedical EngineeringBiophysicstorquelihaksetsidekudoksetmuscle mechanicsmyofascialepimuscularTorqueEpimuscularOrthopedics and Sports Medicinevoimantuotto (fysiologia)faskiatbiomekaniikkaConnective tissueFasciaMyofascialfasciaconnective tissue
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The Effects of Cold Water Immersion on the Recovery of Drop Jump Performance and Mechanics : A Pilot Study in Under-20 Soccer Players

2020

Cold water immersion (CWI) is a popular method used for enhancing recovery from exercise. However, the efficacy of this approach is inconclusive and studies investigating variables contributing to overall performance are scarce. Additionally, few studies have investigated the recovery of stretch-shortening cycle (SSC) performance after a fatiguing SSC task. The SSC occurs naturally in human locomotion and induces a recovery pattern different from isolated muscle contractions (e.g., pure eccentric exercise). Therefore, the main aim of this study was to investigate the effects of a single CWI on jumping performance and mechanics after exhaustive SSC exercise. On a sledge apparatus, 10 male un…

väsymyspalautuminenmedicine.disease_causebiomechanicslcsh:GV557-1198.995JumpingmedicineharjoittelukylmähoitoOriginal Researchlcsh:Sportsexercisebusiness.industryBiomechanicsMechanicsmedicine.anatomical_structurehydrotherapyEccentric exerciseWater immersionSports and Active LivingDrop jumpJoint stiffnesskylpyhoitofatiguebiomekaniikkamedicine.symptomAnklebusinessCreatine kinase activitycryotherapy
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Foot loading in normal and pathological walking

2002

Perusteellinen kävely- ja kuormitusanalyysi on usein tarpeellinen jalkaongelmissa, jotta mahdollinen tukien ja ortoosien valinta sekä alaraajoihin kohdistuvien leikkausten jälkeinen kuntoutus pystytään suorittamaan parhaalla mahdollisella tavalla, toteaa Jarmo Perttunen väitöstutkimuksessaan. Kävelijä tuottaa tukivaiheen aikana alustaan voimia pysty- ja vaakasuunnassa, joita on perinteisesti mitattu voimalevyantureilla. Ne eivät pysty yksistään erottelemaan kuormitusta jalkapohjan eri osien välillä riittävän täsmällisesti. Kiinnostus selvittää kuormitus tarkasti on johtanut kehityksen alkeellisista jalkapohjan mustekuvista hyvin pieniin kengän sisälle asetettaviin mittausantureihin. Perttus…

walkingalaraajatelektromyografiahermo-lihastoimintakuormitusmittausanalyysiplantar pressurejalkapohjatpathological gaitbiomekaniikkajalatkävely
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Development of an immunochromatographic assay based on carbon nanoparticles for the determination of the phytoregulator forchlorfenuron

2013

Rapid analytical methods enabling the determination of diverse targets are essential in a number of research areas, from clinical diagnostics to feed and food quality and safety. Herein, the development of a quantitative immunochromatographic assay for the detection of the synthetic phytoregulator forchlorfenuron (CPPU) is described. The competitive lateral flow immunoassay (LFIA) was based on the immobilization onto a nitrocellulose membrane of an ovalbumin-CPPU conjugate (test line) and on the use of an immunodetection ligand consisting of carbon nanoparticles labeled with an anti-CPPU monoclonal antibody through interaction with a secondary antibody. The presence of CPPU in horticultural…

water samplesCarbon nanoparticlesAnalyteImmunoreactive stripsPyridinesCarbon NanoparticlesBiomedical EngineeringBiophysicsEnzyme-Linked Immunosorbent AssayCPPUBiosensing Techniquesantibody-based immunoassayForchlorfenuronbiosensorHigh-performance liquid chromatographychemistry.chemical_compoundElectrochemistryImmunoassayDetection limitvalidationChromatographyChemistrystrip testPhenylurea Compoundslateral flow immunoassayAntibodies Monoclonalcomputer image-analysisGeneral MedicineCarbonHaptendipstick assayBBP Bioconversionrapid detectionImmunosensingNanoparticlessensitive detectionBiosensorNitrocelluloseBiotechnologyConjugate
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Wildflowers: opportunities for urban landscapes

2022

The concept of “sustainability” is also becoming of great interest in the management of ornamental and territorial greenery. The new trends in the design of green spaces are aimed both at enhancing their “natural” aspects and at researching schemes characterized by lower maintenance costs. Spontaneous vegetation represents a characteristic component of the urban environment and is always adequate to the conditions of the site in which it is located. In this context, the role of spontaneous herbaceous plants becomes fundamental and constitutes an effective response to the current demand for the defence, conservation and enhancement of biodiversity. So far, the use of spontaneous vegetation f…

wildflower ornamental plants urban sustainability biometric characteristic biodiversityHorticultureSettore AGR/02 - Agronomia E Coltivazioni Erbacee
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