Search results for "Biomechanical"

showing 10 items of 524 documents

Influence of formalin fixation on the biomechanical properties of human diaphyseal bone.

2010

Owing to the lack of fresh human bones, formalin-fixed specimens are frequently used in biomechanical testing. However, formalin fixation is assumed to affect the biomechanical properties of bone. The aim of this study was to compare axial and torsional stiffness and bone mineral density in fresh and embalmed human bones. The subtrochanteric regions of 12 pairs of fresh human femora were randomised into two groups for paired comparison. After bone mineral density measurement, one group was preserved in 4% formalin. After 6 weeks, bone mineral density was remeasured and each specimen underwent axial and torsional loading. The formalin group showed significant higher stiffness values for tors…

OrthodonticsBone mineralChemistryBiomedical EngineeringPaired comparisonStiffnessHuman boneFormalin fixedmusculoskeletal systemBiomechanical testingbody regionsFixativesElastic ModulusFormaldehydemedicineHumansFemurStress Mechanicalmedicine.symptomCadaveric spasmBiomedizinische Technik. Biomedical engineering
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Footwear outsole temperature may be more related to plantar pressure during a prolonged run than foot temperature.

2021

Objective. The temperature of the sole of the foot has been suggested as an alternative to the measurement of plantar pressure during running despite the scarce evidence about their relationship. The temperature of the footwear outsole could also be representative of plantar pressure distribution due to its less multifactorial dependence. The aim of the study was to determine if plantar pressure during a prolonged run could be related to plantar temperature, either of the sole of the foot or the footwear outsole.Approach. Thirty recreational runners (15 males and 15 females) performed a 30 min running test on a treadmill. Thermographic images of the sole of the foot and the footwear outsole…

OrthodonticsMalePhysiologybusiness.industryFootPlantar pressureForefootBiomedical EngineeringBiophysicsTemperatureBiomechanical PhenomenaRunningShoesbody regionsThermographyPhysiology (medical)MedicineHumansFemaleTreadmillbusinesshuman activitiesFoot (unit)Physiological measurement
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Retrograde nailing versus locking plate osteosynthesis of proximal humeral fractures: a biomechanical study

2011

Background In locking plate osteosynthesis of proximal humeral fractures, secondary varus malalignment is a specific complication. Retron nails (Tantum AG, Neumunster, Germany), among others, have been designed to improve medial support of the calcar humeri. The aim of our biomechanical study was to examine whether Retron nails provide increased stiffness for axial loads and adequate stiffness for torsional loads when compared with Philos plates (Synthes AG, Umkirch, Germany). Materials and methods Twenty-two fresh-frozen paired humeri were collected. After potting the specimens, intact bones were exposed to sinusoidal axial (10-120 N) and torsional (±2.5 Nm) loading for 8 cycles to calcula…

Orthodonticsanimal structuresOsteosynthesisCalcarbusiness.industryBone ScrewsVarus malalignmentStiffnessGeneral MedicineAnatomyBone NailsProsthesis DesignBiomechanical PhenomenaLocking plateRadiographyFracture Fixation InternalHumeral fractureShoulder FracturesHumansMedicineOrthopedics and Sports MedicineSurgerymedicine.symptombusinessBone PlatesJournal of Shoulder and Elbow Surgery
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A Statistical Model of Spine Shape and Material for Population-Oriented Biomechanical Simulation

2021

In population-oriented ergonomics product design and musculoskeletal kinetics analysis, digital spine models of different shape, pose and material property are in great demand. The purpose of this study was to construct a parameterized finite element spine model with adjustable spine shape and material property. We used statistical shape model approach to learn inter-subject shape variations from 65 CT images of training subjects. Second order polynomial regression was used to model the age-dependent changes in vertebral material property derived from spatially aligned CT images. Finally, a parametric spine generator was developed to create finite element instances of different shapes and m…

Orthodonticsmallintaminenpopulation anatomy modellingeducation.field_of_studyGeneral Computer ScienceComputer sciencePopulationGeneral Engineeringstatistical shape modellingStatistical modelfinite element analysisspine modellingTK1-9971Spine (zoology)anatomiaselkärankaSpine modellingbiomechanical simulationGeneral Materials SciencesimulointibiomekaniikkaElectrical engineering. Electronics. Nuclear engineeringeducationtilastolliset mallitIEEE Access
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Intramedullary nailing vs. palmar locked plating for unstable dorsally comminuted distal radius fractures: A biomechanical study

2010

Abstract Background The purpose of this study was to compare the stability of a 2.4 mm palmar locking compression plate and a new intramedullary nail-plate-hybrid Targon DR for dorsally comminuted distal radius fractures. Methods An extraarticular 10 mm dorsally open wedge osteotomy was created in 8 pairs of fresh frozen human radii to simulate an AO–A3-fracture. The fractures were stabilized using one of the fixation methods. The specimens were loaded axially with 200 N and dorsal-excentrically with 80 N. 2000 cycles of dynamic loading and axial loading-to-failure were performed. Findings Axial loading revealed that intramedullary osteosynthesis (Targon DR: 369 N/mm) was significantly ( p …

Orthodonticsmedicine.medical_specialtyMaterials scienceOsteosynthesisBiophysicsRadiusLocked platingIn Vitro TechniquesCompression (physics)Biomechanical PhenomenaFracture Fixation Intramedullarylaw.inventionSurgeryIntramedullary rodFracture Fixation InternalFixation (surgical)lawLoad to failureFresh frozenmedicineHumansOrthopedics and Sports MedicineRadius FracturesBone PlatesFractures ComminutedClinical Biomechanics
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ACUTE INFANTILE SPINAL MUSCULAR ATROPHY

1990

Biopsy as well as autopsy studies of a child who died 8 weeks after birth from the acute infantile form of spinal muscular atrophy revealed classical morphological changes, including degeneration and loss of motoneurons in the spinal cord, loss of large myelinated fibres in anterior roots and neurogenic atrophy in muscle. New ultrastructural findings include massive muscle cell elimination by apoptosis with the formation of membrane-bound muscle cell fragments, apoptotic bodies. In addition, numerous immature muscle fibres were observed. The morphological findings raise the possibility that in a severely growth-retarded muscle, the process of muscle cell apoptosis removes the peripheral tar…

Pathologymedicine.medical_specialtyCell SurvivalBiopsySpinal Muscular Atrophies of ChildhoodMuscular Atrophy SpinalAtrophyAnterior Horn CellmedicineHumansMyocyteMuscle contracturebusiness.industryMusclesInfant NewbornSpinal muscular atrophymedicine.diseaseSpinal cordBiomechanical PhenomenaTissue Degenerationmedicine.anatomical_structureSpinal CordApoptosisAcute DiseaseFemaleNeurology (clinical)businessBrain
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Ultrasound-based testing of tendon mechanical properties: a critical evaluation.

2015

In the past 20 years, the use of ultrasound-based methods has become a standard approach to measure tendon mechanical properties in vivo. Yet the multitude of methodological approaches adopted by various research groups probably contribute to the large variability of reported values. The technique of obtaining and relating tendon deformation to tensile force in vivo has been applied differently, depending on practical constraints or scientific points of view. Divergence can be seen in 1) methodological considerations, such as the choice of anatomical features to scan and to track, force measurements, or signal synchronization; and 2) in physiological considerations related to the viscoelas…

Pathologymedicine.medical_specialtyPhysiologybusiness.industryUltrasoundMeasure (physics)TendonBiomechanical PhenomenaTendonsmedicine.anatomical_structurePhysiology (medical)medicineHumansAponeurosisbusinessBiomedical engineeringUltrasonographyJournal of applied physiology (Bethesda, Md. : 1985)
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Hereditariness of Aortic Tissue: In-Vitro Time-Dependent Failure of Human and Porcine Specimens

2018

This study aims to investigate the time dependent failure of aortic tissues for pathological and healthy samples by biomechanical testing. The experimental campaign has involved human pathological tissue and healthy swine tissue as preliminary study towards the development of novel failure criteria.

Pathologymedicine.medical_specialtySettore MED/09 - Medicina Internabusiness.industryRenewable Energy Sustainability and the EnvironmentEnergy Engineering and Power TechnologyComputer Science Applications1707 Computer Vision and Pattern RecognitionBiomechanical testingmedicine.diseaseATAAAneurysmIn vitrocreep failureIndustrial and Manufacturing Engineeringaortic tissue biomechanicAneurysmComputer Networks and CommunicationArtificial IntelligenceAortic tissuehereditarineMedicinebusinessSettore ICAR/08 - Scienza Delle CostruzioniPathologicalInstrumentation
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Patient-specific simulation of the intrastromal ring segment implantation in corneas with keratoconus

2015

Purpose The purpose of this study was the simulation of the implantation of intrastromal corneal-ring segments for patients with keratoconus. The aim of the study was the prediction of the corneal curvature recovery after this intervention. Methods Seven patients with keratoconus diagnosed and treated by implantation of intrastromal corneal-ring segments were enrolled in the study. The 3D geometry of the cornea of each patient was obtained from its specific topography and a hyperelastic model was assumed to characterize its mechanical behavior. To simulate the intervention, the intrastromal corneal-ring segments were modeled and placed at the same location at which they were placed in the s…

Patient-Specific ModelingKeratoconusmedicine.medical_specialtyMaterials sciencegenetic structuresINGENIERIA MECANICAkeratoconusFinite Element AnalysisBiomedical EngineeringCurvatureKeratoconusMean differenceBiomaterialsCorneaCorneaOphthalmologycorneabiomechanical simulationmedicineHumans3d geometryMechanical PhenomenaCorneal curvatureBiomechanical simulationintrastromal ring segmentsMechanical ProcessesProstheses and ImplantsPatient specificmedicine.diseaseeye diseasesSurgeryBiomechanical Phenomenamedicine.anatomical_structureIntrastromal ring segmentsMechanics of Materialssense organsLENGUAJES Y SISTEMAS INFORMATICOS
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Muscle training for bone strength

2006

The main function of bone is to provide the mechanical integrity for locomotion and protection; accordingly, bone mass and architecture are adjusted to control the strains produced by mechanical load and muscular activity. Age-related patterns involve peak bone mass during growth, a plateau in adulthood, and bone loss during aging. The decline in bone mass and structural integrity results in increased risk of fractures, particularly in post-menopausal women. Athletes competing in strength and power events, such as weight-lifting and jumping, have superior bone mass and structure compared with their untrained counterparts in all age groups. Exercise seems to be most effective during rapid gr…

Peak bone massAgingmedicine.medical_specialtyMuscle trainingWeight Liftingmedicine.disease_causeWeight-bearingWeight-BearingFractures BoneJumpingPhysical medicine and rehabilitationBone DensityRisk FactorsmedicineHumansAerobic exerciseFunctional abilityExercise physiologyExercisebiologyAthletesbusiness.industryMusclesbiology.organism_classificationBiomechanical PhenomenaPhysical therapyOsteoporosisFemaleGeriatrics and GerontologybusinessAging Clinical and Experimental Research
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