Search results for "Biotechnologie"
showing 10 items of 47 documents
Neuropeptide FF increases M2 activation and self-renewal of adipose tissue macrophages
2017
The quantity and activation state of adipose tissue macrophages (ATMs) impact the development of obesity-induced metabolic diseases. Appetite-controlling hormones play key roles in obesity; however, our understanding of their effects on ATMs is limited. Here, we have shown that human and mouse ATMs express NPFFR2, a receptor for the appetite-reducing neuropeptide FF (NPFF), and that NPFFR2 expression is upregulated by IL-4, an M2-polarizing cytokine. Plasma levels of NPFF decreased in obese patients and high-fat diet-fed mice and increased following caloric restriction. NPFF promoted M2 activation and increased the proliferation of murine and human ATMs. Both M2 activation and increased ATM…
Kawasaki disease: Guidelines of Italian Society of Pediatrics, part II - Treatment of resistant forms and cardiovascular complications, follow-up, li…
2018
Abstract This second part of practical Guidelines related to Kawasaki disease (KD) has the goal of contributing to prompt diagnosis and most appropriate treatment of KD resistant forms and cardiovascular complications, including non-pharmacologic treatments, follow-up, lifestyle and prevention of cardiovascular risks in the long-term through a set of 17 recommendations. Guidelines, however, should not be considered a norm that limits the treatment options of pediatricians and practitioners, as treatment modalities other than those recommended may be required as a result of peculiar medical circumstances, patient’s condition, and disease severity or individual complications.
Experimental Setup with Chaotic and Periodic Excitations for Cell Growth Studies
2020
The paper presents circuits used for excitation living cells to increase their growth rate. The main novelty is the proposal of using chaotic oscillations for the electromagnetic excitation. The research is in a preliminary phase and no conclusions have been yet derived for applications in biotechnology.
Influence of a reducing environment on the bioconversion of fatty acids to lactones and methyl-ketones by microorganisms : cellular and enzymatic app…
2002
National audience
Efficacy and safety of tocilizumab in adult-onset Still's disease: Real-life experience from the international AIDA registry
2022
© 2022 Elsevier Inc.Background/objectives: Long-term efficacy and safety of tocilizumab (TCZ) in adult-onset Still's disease (AOSD) mostly derive from small case series. Herein we report a registry-based study investigating TCZ efficacy and safety in a cohort of patients with AOSD evaluated by clinical and serum inflammatory markers as well as drug retention rate analysis. Methods: This is an international multicentre study analyzing data from patients with AOSD regularly enrolled in the AIDA registry. TCZ efficacy was evaluated between baseline and last follow-up assessment in terms of changes in the Pouchot score and laboratory findings. Drug-retention rate was estimated by the Kaplan-Mei…
Distinguishing between two crus : as easy as picking the right side ? : Effect of expertise on conceptual and perceptual representations of Beaujolai…
2017
L’expertise a été étudiée en psychologie cognitive afin de comprendre les mécanismes psychologiques et les compétences intervenant dans différents domaines d’expertise. Dans le domaine du vin, les quelques études menées suggèrent que les experts organiseraient leurs connaissances autour de « prototypes » de couleur ou de cépage. L’objectif général de cette thèse visait à répondre aux questionnements théoriques concernant les représentations des vins d’experts et de novices, ainsi qu’aux questionnements de la filière concernant les perceptions des vins du Beaujolais. Pour cela, l’effet de l’expertise sur les représentations des vins a été évalué en comparant les performances de trois panels …
The Characteristics of initial public offering for innovative small and medium-sized firms: the case of young french bio/medtech firms
2017
The various government measures in favor of innovative SMEs, the number of biotechnology firms listed on the stock exchange over the last ten years, the characteristics of their pre-introduction financing are different factors that justify a particular interest for these firms and their methods of introduction (discount, float, quotation procedure). Different tests of mean difference have significant results. Comparing with a control sample, we found that SME in this sector are listed on the stock exchange faster, by making greater use of the open-price offer procedure (OPO) and are subject to greater prior financing by financial stockholders. Although the ownership of the capital and the d…
Increased electron donor and electron acceptor characters enhance the adhesion between oil droplets and cells of Yarrowia lipolytica as evaluated by …
2003
The adhesion of methyl ricinoleate droplets to cells of the yeast Yarrowia lipolytica was investigated. A new cytometric method, relying on the double staining of fatty globules with Nile Red and of cells with Calcofluor, enabled us to quantify methyl ricinoleate droplet adhesion to cells precultured on a hydrophilic or on a hydrophobic carbon source. In this last case, droplet adsorption was enhanced and a MATS (microbial adhesion to solvents) test revealed that this increase was due to Lewis acid-base interactions and not to an increase in the hydrophobic properties of the cell surface. These preliminary results demonstrate that the developed cytometric method is promising for various app…
Gene flow from oilseed rape to weedy species
2003
The assessment of the likelihood of transgene spread from cultivated species to their wild relatives is relevant for oilseed rape (Brassica napus, AACC, 2n=38) as it is partially allogamous and pre...
Avis en réponse à la saisine HCB - dossier C/NL/06/01_001. Paris, le 17 octobre 2018
2018
Le Haut Conseil des biotechnologies (HCB) a été saisi le 14 août 2018 par les autorités compétentes françaises (le ministère de l’Agriculture et de l’Alimentation) d’une demande d’avis relative au dossier C/NL/06/01_001 de demande de renouvellement d’autorisation de mise sur le marché de la lignée d’oeillets génétiquement modifiés 123.8.12 (identificateur unique FLO- 40689-6) à des fins d’importation et de commercialisation de fleurs coupées. Ce dossier a été déposé par la société Suntory Flowers Limited auprès des autorités compétentes néerlandaises sur le fondement de la directive 2001/18/CE. Conformément à cette directive, la Commission européenne a adressé le rapport d’évaluation des Pa…