Search results for "Bipolar"
showing 10 items of 395 documents
The burden of mood-disorder/cerebrovascular disease comorbidity: essential neurobiology, psychopharmacology, and physical activity interventions
2017
Cardio-vascular diseases (CVDs) and CVD-related disorders (including cerebrovascular diseases; CBVDs) are a major public health concern as they represent the leading cause of mortality and morbidity in developed countries. Patients with CVDs and CBVDs co-morbid with mood disorders, especially bipolar disorder (BD) and major depressive disorder (MDD), suffer reduced quality-of-life and significant disability adjusted for years of life and mortality. The relationship between CVDs/CBVDs and mood disorders is likely to be bidirectional. Evidence for shared genetic risk of pathways involved in stress reaction, serotonin or dopamine signalling, circadian rhythms, and energy balance was reported i…
Characteristics of Bipolar Patients with Cognitive Impairment of Suspected Neurodegenerative Origin: A Multicenter Cohort
2021
Bipolar disorder is associated with an increased risk of dementia with aging. Little is known regarding this association, limiting appropriate diagnosis and management. We aimed to describe the characteristics of bipolar patients with late cognitive impairment for whom the hypothesis of an underlying neurodegenerative disease had been raised. We performed a retrospective multicenter study, recruiting bipolar patients over 50 years old from five French tertiary memory centers who had undergone cerebrospinal fluid (CSF) biomarker assessment for Alzheimer’s disease (AD). Clinical, neuropsychological, and paraclinical characteristics were analyzed and 78 patients were included. The mean age at …
Pensiero e difese nei disturbi bipolari. Studio clinico e psicopatologico su bipolari I e bipolari II. Thinking organization and defense mechanisms i…
2013
Obiettivi. Scopo del presente studio è esplorare il funzionamento psichico dei soggetti con disturbo bipolare I e II attraverso l’analisi e il confronto degli stili di pensiero e dei pattern difensivi. Metodi. Nel corso di un intero anno solare (2009-2010), presso la clinica Psichiatrica del Policlinico Universitario di Palermo sono stati reclutati 29 pazienti con disturbo bipolare I e II. È stato somministrato il seguente protocollo: Wechsler Adult Intelligent Scale-R (WAIS-R) per valutare il funzionamento cognitivo generale; Defense Mechanisms Inventory (DMI) per misurare i pattern difensivi. Sono stati quindi ana- lizzati e confrontati i risultati ai due reattivi. Risultati. I soggetti c…
Cannabis Use and the Risk for Psychosis and Affective Disorders.
2019
Objective: This review discusses the relationship between cannabis use and psychotic, bipolar, depressive, and anxiety disorders, as well as suicide. It summarizes epidemiological evidence from cross-sectional and long-term prospective studies and considers possible etiological mechanisms. Methods: Systematic reviews and methodologically robust studies in the field (from inception to February 2019) were identified using a comprehensive search of Medline, PsychINFO, and Embase and summarized using a narrative synthesis. Results: Consistent evidence, both from observational and experimental studies, has confirmed the important role of cannabis use in the initiation and persistence of psychoti…
A study of physical processes in microplasma capillary discharges
2011
We continue the research of low-pressure capillary discharge lamps of 500 μ m in radius in Ar/Hg, Kr/Hg and Xe/Hg mixtures. In the previous paper, an experimental approach which combines the optical emission spectroscopy (OES) and tomographic methods was developed to study the capillary discharge. The present work is focused on interpretation of the tomographic reconstruction results for understanding the physical processes occurring in a capillary plasma. Analyzing the results of reconstruction, it was concluded that the radial profiles of Ar, Kr and Xe emission coefficients are in a good agreement with the Schottky theory. According to the Schottky model, ionization processes in plasma a…
Estudio de la función inmunitaria en pacientes esquizofrénicos y bipolares tipo I
2007
RESUMEN El estudio de la función inmunitaria en los pacientes psicóticos ha adquirido un protagonismo creciente, como consecuencia del avance en los conocimientos acerca de las implicaciones del sistema inmune en el funcionamiento del sistema nervioso y de recientes descubrimientos sobre anomalías de la función inmunitaria en pacientes psicóticos. En la actualidad se conoce la interrelación entre sistema nervioso, sistema inmune y conducta, y gracias a esta comunicación se facilita una respuesta integrada del organismo, cuyo fin sería el mantenimiento de la homeostasis. Estos hechos han llevado al planteamiento de estrategias de investigación multidisciplinaria, dando lugar a la aparición d…
A validated multi-scale model of a novel electrodialytic acid-base flow battery
2020
Electrical energy storage is crucial for a deeper penetration of intermittent renewable energies, e.g. solar and wind. The Acid/Base Flow Battery (AB-FB) is a novel, sustainable, environmental-friendly storage technology with high energy density1. The process is based on reversible electrodialytic techniques that convert the electrical energy in the chemical energy associated to pH gradients and vice versa. The bipolar membrane electrodialysis process operates in the charge phase, while the bipolar membrane reverse electrodialysis in the discharge phase. The stack consists of repetitive units, called triplets, made up of an anion-exchange membrane, a bipolar membrane, and a cation-exchange …
Many-body Green's function theory for electron-phonon interactions: ground state properties of the Holstein dimer
2015
We study ground-state properties of a two-site, two-electron Holstein model describing two molecules coupled indirectly via electron-phonon interaction by using both exact diagonalization and self-consistent diagrammatic many-body perturbation theory. The Hartree and self-consistent Born approximations used in the present work are studied at different levels of self-consistency. The governing equations are shown to exhibit multiple solutions when the electron-phonon interaction is sufficiently strong whereas at smaller interactions only a single solution is found. The additional solutions at larger electron-phonon couplings correspond to symmetry-broken states with inhomogeneous electron de…
Borderline Personality in Patients with Poly-Diagnoses Treated for a Bipolar Disorder
2019
Some patients with dysphoria, explosive behaviour, or suicidal ideation, may receive a diagnosis of, and treatment for Bipolar Disorder (BD) and, not infrequently. The coexistence of these two diagnoses has been explained in different ways. Some authors include the BPD in the bipolar spectrum; others are sceptical about the existence of real comorbidity, suggesting a misdiagnosis. This study aimed to assess the personality of this group of poly-diagnosed patients (PolyD) and hypothesised they had a pathological borderline organisation. Via the administration of the Schedler Westen Assessment Procedure (SWAP-200), we compared PolyD patients with those suffering from BPD or BD only. We perfor…
Atención y procesamiento emocional en personas con trastorno bipolar
2014
Las personas con trastorno bipolar se caracterizan por una desregulación emocional que afecta a cómo atienden a la información que les rodea. Investigaciones recientes han encontrado sesgos atencionales en las personas con trastorno bipolar, tanto cuando su estado de ánimo es bajo (mayor atención a palabras negativas y rostros tristes) como cuando su estado de ánimo es elevado (mayor atención a palabras positivas y caras alegres). Es importante destacar que, en personas con depresión, estos sesgos pueden entrenarse de manera que disminuye la sintomatología afectiva. Esta opción podría contemplarse como una nueva alternativa de intervención en el trastorno bipolar.