Search results for "Birth"

showing 10 items of 606 documents

Body size at birth and age-related macular degeneration in old age

2019

Purpose To study associations between body size at birth and age-related macular degeneration (AMD) in old age. Methods The study sample consists of 1497 community-dwelling individuals (56.1% women) aged 67-89 years with birth data and retinal data collected twice in old age 5 years apart. Birth data (weight, length, birth order) were extracted from original birth records. Digital retinal photographs were graded to determine AMD status. Data on covariates were collected at the baseline physical examination in old age. Multivariable regression analyses were used to study the association between birth data and AMD adjusting for known confounding factors, including birth year cohort effects. R…

genetic structuresMACULOPATHYPopulationArticle03 medical and health sciences0302 clinical medicineMedicinesyntymäpainoCORONARY-HEART-DISEASE3125 Otorhinolaryngology ophthalmology10. No inequalityeducationage-related macular degenerationBirth YearPOPULATIONeducation.field_of_studyHYPERTENSIONbusiness.industryIncidence (epidemiology)age‐related macular degenerationGeneral MedicineMacular degenerationbody size at birthmedicine.diseaseObesityeye diseasessilmänpohjan ikärappeumaPREVALENCELIFEOphthalmologyBirth orderCohort effectQuartile030221 ophthalmology & optometrySUBSEQUENT RISKsense organsWEIGHTbusiness030217 neurology & neurosurgeryDemography
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Prolonging in utero-like oxygenation after birth diminishes oxidative stress in the lung and brain of mice pups☆

2013

Background Fetal-to-neonatal transition is associated with oxidative stress. In preterm infants, immaturity of the antioxidant system favours supplemental oxygen-derived morbidity and mortality. Objectives To assess if prolonging in utero-like oxygenation during the fetal-to-neonatal transition limits oxidative stress in the lung and brain, improving postnatal adaptation of mice pups. Material and methods Inspiratory oxygen fraction (FiO2) in pregnant mice was reduced from 21% (room air) to 14% (hypoxia) 8–12 h prior to delivery and reset to 21% 6–8 h after birth. The control group was kept at 21% during the procedure. Reduced (GSH) and oxidized (GSSG) glutathione and its precursors [γ-glut…

gsr (glutathione reductase gene)pgd phosphogluconate dehydrogenase geneGPX1FiO2 inspiratory oxygen fractionγ-GC (gamma-glutamyl cysteine)PhysiologyBiochemistryMice0302 clinical medicinePregnancyquinone oxidoreductase 1) [noq1 (NAD(P)H]NAD(P)H Dehydrogenase (Quinone)gapdh glyceraldehyde-3-phosphate dehydrogenase geneP7 1 week after birthGSH (reduced glutathione)Oxidoreductases Acting on Sulfur Group Donorsme1 (malic enzyme 1 gene)glutathioneLungSpO2 oxygen saturationlcsh:QH301-705.5γ-GC–NEM gamma-glutamyl cysteine covalently bonded to N-ethylmaleimidechemistry.chemical_classification0303 health sciencesGSSG oxidized glutathioneGlutathione peroxidaseO14 (hypoxia group FiO2=14%)Brainm/z mass-to-charge ratioG18 18th day of gestationCell Hypoxia3. Good healthpgd (phosphogluconate dehydrogenase gene)In uterogclm glutamylcysteine ligase modifier subunit genesrnx1 sulfiredoxin 1 genelcsh:Medicine (General)me1 malic enzyme 1 genesrnx1 (sulfiredoxin 1 gene)gclm (glutamylcysteine ligase modifier subunit gene)γ-GC–NEM (gamma-glutamyl cysteine covalently bonded to N-ethylmaleimide)trxnd1 (thioredoxin reductase 1 gene)redox regulation03 medical and health sciencesnoq1 NAD(P)H:quinone oxidoreductase 1γ-GC gamma-glutamyl cysteineCySH L-cysteinePregnancyg6pdx (glucose 6 phosphate dehydrogenase gene)GlutathioneOxygenationgapdh (glyceraldehyde-3-phosphate dehydrogenase gene)medicine.diseaseMice Inbred C57BLOxygenP1 24 h after birthGCL glutamylcysteine ligasechemistryOxidative stressRedox regulationNEM (N-ethylmaleimide)O14 hypoxia group (FiO2=14%)GSH reduced glutathioneClinical Biochemistrymedicine.disease_causechemistry.chemical_compoundGlutathione Peroxidase GPX1GS–NEM reduced glutathione covalently bonded to N-ethylmaleimideSpO2 (oxygen saturation)oxidative stressg6pdx glucose 6 phosphate dehydrogenase genelcsh:R5-920GSSG (oxidized glutathione)G18 (18th day of gestation)gsr glutathione reductase geneGlutathionegpx1 glutathione peroxidase 1 genemedicine.anatomical_structurem/z (mass-to-charge ratio)LC–MS/MS (liquid chromatography coupled to tandem mass spectrometry)FemaleLC–MS/MS liquid chromatography coupled to tandem mass spectrometryO21 (normoxia group FiO2=21%)paO2 (partial pressure of oxygen)gpx1 (glutathione peroxidase 1 gene)Research Papernoq1 (NAD(P)H:quinone oxidoreductase 1)CySH (l-cysteine)FiO2 (inspiratory oxygen fraction)CyS–NEM (cysteine covalently bonded to N-ethylmaleimide)030225 pediatricsmedicineP7 (1 week after birth)AnimalsGCL (glutamylcysteine ligase)P1 (24 h after birth)O21 normoxia group (FiO2=21%)CyS–NEM cysteine covalently bonded to N-ethylmaleimide030304 developmental biologyGlutathione PeroxidaseLungOrganic ChemistryGS–NEM (reduced glutathione covalently bonded to N-ethylmaleimide)trxnd1 thioredoxin reductase 1 geneMolecular biologypaO2 partial pressure of oxygenAnimals NewbornGene Expression Regulationlcsh:Biology (General)NEM N-ethylmaleimidefetal-to-neonatal transitionoxygenOxidative stressFetal-to-neonatal transition
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Five insights from the Global Burden of Disease Study 2019

2020

The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 provides a rules-based synthesis of the available evidence on levels and trends in health outcomes, a diverse set of risk factors, and health system responses. GBD 2019 covered 204 countries and territories, as well as first administrative level disaggregations for 22 countries, from 1990 to 2019. Because GBD is highly standardised and comprehensive, spanning both fatal and non-fatal outcomes, and uses a mutually exclusive and collectively exhaustive list of hierarchical disease and injury causes, the study provides a powerful basis for detailed and broad insights on global health trends and emerging challenges. GBD …

health care deliveryMaleHumans -- MalatiesOutcome Assessmentglobal healthDiseaseReviewinsights030204 cardiovascular system & hematologySocioeconomic FactorgeographyGlobal Burden of DiseaseNoncommunicable Diseasedisease burdenCarga Global de Enfermedades0302 clinical medicineRisk FactorsOutcome Assessment Health CareHealth careGlobal healthDelivery of health carehealth outcomesmiddle income countrybirth rate030212 general & internal medicineBirth Ratehealth outcomes health system responses economic developmentFactores de Riesgopublic healthhealth care costGeneral MedicineRisk factor (computing)humanities3. Good healthfemalepriority journalrisk factorhealth system responsesepidemiologyTERRITORIESpoliticsCLINICAL-TRIALSmedicine.medical_specialtyBirth Rate; Delivery of Health Care; Global Burden of Disease; Noncommunicable Diseases; Outcome Assessment Health Care; Risk Factors; Socioeconomic Factors; Wounds and Injuries; epidemiologyinjury2019195 COUNTRIESArticleGlobal Burden of Diseases health outcomes risk factors health system responsesHealthcare improvement science Radboud Institute for Health Sciences [Radboudumc 18]03 medical and health sciencessocioeconomicsmedicineSYSTEMATIC ANALYSISHumansGlobal Burden of Disease StudyhumanEpidemiologiaNoncommunicable DiseasesDisease burdenActuarial sciencehigh income countrybusiness.industryRisk FactorWounds and InjuriePublic healthagingHealth careeconomicsNon-communicable diseasemedicine.diseaseSalut públicaeconomic developmentEnfermedadesnon communicable disease//purl.org/pe-repo/ocde/ford#3.02.00 [https]Health CareRisk factorsSocioeconomic Factorspopulation growthLife expectancylife expectancyWounds and InjuriesNAPrestación de Atención de Saludglobal disease burdenbusinessDelivery of Health Carelow income country
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Birth and recognition of new States

2023

Birth and recognition of new States. 1. Introduction. 2. Modalities of State recognition. 3. Discretionary nature of recognition. 4. Emergence of the obligation not to recognise.

international subjectivitystateUNESCO::CIENCIAS JURÍDICAS Y DERECHO::Derecho internacionalbirth and recognition of statesinternational law
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What is your couple type? Gender ideology, housework-sharing, and babies

2015

AbstractBACKGROUNDIt is increasingly acknowledged that not only gender equality but also gender ideology plays a role in explaining fertility in advanced societies. In a micro perspective, the potential mismatch between gender equality (i.e., the actual sharing taking place in a couple) and gender ideology (i.e., attitudes and beliefs regarding gender roles) may drive childbearing decisions.OBJECTIVEThis paper assesses the impact of consistency between gender equality in attitudes and equality in the division of household labour on the likelihood of having another child, for different parities.METHODSRelying on two-wave panel data of the Bulgarian, Czech, French, Hungarian, and Lithuanian G…

jel:Z0CzechHOUSEHOLD LABORPERCEPTIONSFertility gender equity gender equality gender couple typology GGS survey5. Gender equalityMENS CHILDBEARING DESIRES; HOUSEHOLD LABOR; FERTILITY INTENTIONS; 2ND BIRTHS; CHILD-CARE; EUROPE; EQUALITY; EQUITY; PERCEPTIONS; ATTITUDESBulgarianSettore SECS-S/05 - Statistica Sociale050207 economics10. No inequalityProxy (statistics)media_common05 social sciencesfertility gender couple typology gender equality gender equity GGS16. Peace & justiceCHILD-CARElcsh:HB848-3697Feeling050902 family studieslanguagePublic sphereIdeologymedicine.symptomPsychologyEQUITYSocial psychologyTypologyEUROPEmedia_common.quotation_subjectGENDER EQUITYFertilityConsistency (negotiation)0502 economics and businessmedicineFERTILITYGENERATIONS AND GENDER SURVEYSMENS CHILDBEARING DESIRES2ND BIRTHSATTITUDESEgalitarianismDemographyDisappointmentGENDER EQUALITYCOUPLE TYPEPrivate sphereSettore SECS-S/04 - Demografiagender couple typologyGGSlanguage.human_languageGENDER EQUALITY GENDER EQUITY COUPLE TYPE FERTILITY GENERATIONS AND GENDER SURVEYSFERTILITY INTENTIONSjel:J13jel:J1jel:J12jel:J16lcsh:Demography. Population. Vital eventsDemographic economics0509 other social sciencesEQUALITYBreadwinner modelPanel data
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Prematurity and overlap between reading and arithmetic: The cognitive mechanisms behind the association

2019

It is well-known that very preterm children perform at lower levels than full-term children in reading and arithmetic at school. Whether the lower performance levels of preterm children in these two separate domains have the same or different origins, however, is not clear. The present study examined the extent to which prematurity is associated with the overlap (i.e., common variance) of reading and arithmetic among Finnish school beginners. We also examined the extent to which the association of prematurity with the overlap between reading and arithmetic is due to different prereading skills, basic number skills, and general cognitive abilities. The participants (age 6-7) consisted of 193…

kognitiiviset taidotmedia_common.quotation_subjectLEARNING-DIFFICULTIESAcademic achievementPREDICTlukeminenEducationMATHEMATICSNEURODEVELOPMENTAL OUTCOMESreadingReading (process)aritmetiikkaACADEMIC-ACHIEVEMENTDevelopmental and Educational Psychologyoverlapta5160501 psychology and cognitive sciencesfirst gradeABILITIESArithmeticAssociation (psychology)preterm childrenta515media_commonVERY PRETERMlanguage4. Educationprematurity05 social sciences050301 educationCognitionDOUBLE-DEFICIT HYPOTHESISlukeminen (toiminta)ta3142Variance (accounting)arithmeticCHILDREN BORN PRETERMVery pretermVERY LOW BIRTH WEIGHTSKILLSkeskosetSCHOOL-ACHIEVEMENT6163 LogopedicsPsychology0503 education050104 developmental & child psychologyContemporary Educational Psychology
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Secular rise in economically valuable personality traits

2017

Although trends in many physical characteristics and cognitive capabilities of modern humans are well-documented, less is known about how personality traits have evolved over time. We analyze data from a standardized personality test administered to 79% of Finnish men born between 1962 and 1976 (n = 419,523) and find steady increases in personality traits that predict higher income in later life. The magnitudes of these trends are similar to the simultaneous increase in cognitive abilities, at 0.2-0.6 SD during the 15-y window. When anchored to earnings, the change in personality traits amounts to a 12% increase. Both personality and cognitive ability have consistent associations with famil…

kognitiiviset taidottulotMaleParentsPersonality Inventorymedia_common.quotation_subjecttulotasoCROSS-TEMPORAL METAANALYSISSocial Sciences050109 social psychologySTUDENTSBig Five personality traits and cultureDevelopmental psychologyPSYCHOLOGYCognitionGENERATION MEcognitive ability0502 economics and businessPersonalityHumans0501 psychology and cognitive sciences050207 economicsPersonality testBig Five personality traitsta512media_commonMultidisciplinaryta511EarningsIQ GAINSSiblings05 social sciencespersoonallisuuden piirteetcohort effectsCognitionFlynn effectEDUCATIONBIRTH COHORT DIFFERENCESPERFORMANCEABILITYFlynn effectCohort effectIncomepersonality traitsINSTITUTIONS511 EconomicsPsychologyearningsPersonality
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Early-Life Factors as Predictors of Age-Associated Deficit Accumulation Across 17 Years From Midlife Into Old Age

2022

Abstract Background Early-life exposures have been associated with the risk of frailty in old age. We investigated whether early-life exposures predict the level and rate of change in a frailty index (FI) from midlife into old age. Methods A linear mixed model analysis was performed using data from 3 measurement occasions over 17 years in participants from the Helsinki Birth Cohort Study (n = 2 000) aged 57–84 years. A 41-item FI was calculated on each occasion. Information on birth size, maternal body mass index (BMI), growth in infancy and childhood, childhood socioeconomic status (SES), and early-life stress (wartime separation from both parents) was obtained from registers and health ca…

life coursegerasteniaAgingFrailtyfrailtyriskitekijätelämänkaari3142 Public health care science environmental and occupational healthBody Mass IndexCohort Studies3141 Health care sciencevarhaislapsuusikääntyminenSocial ClassRisk FactorsHumansrisk factorssyntymäpainobirth factorsGeriatrics and GerontologyThe Journals of Gerontology: Series A
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Non-melancholic depressive symptoms are associated with above average fat mass index in the Helsinki birth cohort study

2022

AbstractThere is an existing link between two of the most common diseases, obesity and depression. These are both of great public health concern, but little is known about the relationships between the subtypes of these conditions. We hypothesized that non-melancholic depressive symptoms have a stronger relationship with both body composition (lean mass and fat mass) and dysfunctional glucose metabolism than melancholic depression. For this cross-sectional study 1510 participants from the Helsinki Birth Cohort Study had their body composition evaluated as lean mass and fat mass (Lean Mass Index [LMI, kg/m2] + Fat Mass Index [FMI kg/m2] = Body Mass Index). Participants were evaluated for dep…

masennusglukoosiaineenvaihduntaINVENTORYpsychologymedical researchDISEASECohort StudiesBMIaineenvaihduntahäiriötmielenterveyshäiriötHumansrisk factorskohorttitutkimusaineenvaihduntakehonkoostumusMETABOLIC SYNDROMEMultidisciplinaryOVERWEIGHTDepressionINSULINPREVALENCEsigns and symptomsCross-Sectional StudiesGlucosePHYSICAL-ACTIVITY3121 General medicine internal medicine and other clinical medicineOBESITYBirth CohortHEALTHneurophysiologymetabolism
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Depression and Violence in Adolescence and Young Adults: Findings From Three Longitudinal Cohorts

2017

Objective Despite recent research demonstrating associations between violence and depression in adults, links in adolescents are uncertain. This study aims to assess the longitudinal associations between young people’s depression and later violent outcomes. Method We used data from three cohorts with different measurements of depression exposures and subsequent violent outcomes. In a Dutch community cohort Research on Adolescent Development And Relationships (RADAR; N = 623) and a population-based British birth cohort Avon Longitudinal Study of Parents and Children (ALSPAC; N = 4,030), we examined the longitudinal links between adolescent depressive symptoms and violent behaviors from age 1…

masennusyoung adultsVICTIMIZATIONlongitudinal515 Psychologylongitudinal researchdepression (mental disorders)CHILDRENpitkittäistutkimusyoung peopleviolencenuoretMENTAL-DISORDERScohort studyväkivaltaisuuskohorttitutkimusPOPULATIONnuoret aikuisetBIRTH COHORT513 LawBIPOLAR DISORDERbirth cohortDEPRESSIONviolence (traits)CRIMECONDUCT PROBLEMS5144 Social psychology5141 SociologydepressionHEALTHCOMORBIDITYadolescents and young adultsVIOLENCE
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