Search results for "Blocking"
showing 10 items of 164 documents
ATHENA WFI optical blocking filters development status toward the end of the instrument phase-A
2018
Copyright 2018 Society of Photo-Optical Instrumentation Engineers (SPIE). One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited. The Wide Field Imager (WFI) is one of the two instruments of the ATHENA astrophysics space mission approved by ESA as the second large mission in the Cosmic Vision 2015-2025 Science Programme. The WFI, based on a large array of depleted field effect transistors (DEPFET), will provide imaging in the 0.2-15 keV band over a 40'x40' field of view, simultaneously with spectrally an…
Filters for X-Ray Detectors on Space Missions
2022
Thin filters and gas-tight windows are used in space to protect sensitive X-ray detectors from out-of-band electromagnetic radiation, low-energy particles, and molecular contamination. Though very thin and made of light materials, filters are not fully transparent to X-rays. For this reason, they ultimately define the detector quantum efficiency at low energies. In this chapter, we initially provide a brief overview of filter materials and specific designs adopted on space experiments with main focus on detectors operating at the focal plane of grazing incidence X-ray telescopes. We then provide a series of inputs driving the design and development of filters for high-energy astrophysics sp…
Functional characterization of the sea urchin sns chromatin insulator in erythroid cells.
2005
Abstract Chromatin insulators are regulatory elements that determine domains of genetic functions. We have previously described the characterization of a 265 bp insulator element, termed sns, localized at the 3′ end of the early histone H2A gene of the sea urchin Paracentrotus lividus. This sequence contains three cis-acting elements (Box A, Box B, and Box C + T) all needed for the enhancer-blocking activity in both sea urchin and human cells. The goal of this study was to further characterize the sea urchin sns insulator in the erythroid environment. We employed colony assays in human (K562) and mouse (MEL) erythroid cell lines. We tested the capability of sns to interfere with the communi…
Functional characterization of the enhancer blocking element of the sea urchin early histone gene cluster reveals insulator properties and three esse…
2000
Insulator elements can be functionally identified by their ability to shield promoters from regulators in a position-dependent manner or their ability to protect adjacent transgenes from position effects. We have previously reported the identification of a 265 bp sns DNA fragment at the 3' end of the sea urchin H2A early histone gene that blocked expression of a reporter gene in transgenic embryos when placed between the enhancer and the promoter. Here we show that sns interferes with enhancer-promoter interaction in a directional manner. When sns is placed between the H2A modulator and the inducible tet operator, the modulator is barred from interaction with the basal promoter. However, th…
Polarisation dependent Raman study of single-crystal nickel oxide
2011
Abstract The magnetic domain structure and Raman scattering have been studied in NiO single-crystals with three different (100), (110) and (111) orientations. Twin-domain structure was observed in NiO(100) and NiO(110) single-crystals using cross-polarized optical microscopy. We found that the ratio of the two-magnon (at 1500 cm−1) to the two-phonon (2LO, at 1100 cm−1) Raman bands intensity is sensitive in a particular way to the type of the twin-domain pattern.
Treatment with soluble activin type IIB-receptor improves bone mass and strength in a mouse model of Duchenne muscular dystrophy
2017
Background: Inhibition of activin/myostatin pathway has emerged as a novel approach to increase muscle mass and bone strength. Duchenne muscular dystrophy (DMD) is a neuromuscular disorder that leads to progressive muscle degeneration and also high incidence of fractures. The aim of our study was to test whether inhibition of activin receptor IIB ligands with or without exercise could improve bone strength in the mdx mouse model for DMD. Methods: Thirty-two mdx mice were divided to running and non-running groups and to receive either PBS control or soluble activin type IIB-receptor (ActRIIB-Fc) once weekly for 7 weeks. Results: Treatment of mdx mice with ActRIIB-Fc resulted in significantly…
Analysis on channel bonding/aggregation for multi-channel cognitive radio networks
2010
Channel bonding/aggregation techniques, which assemble several channels together as one channel, could be used in cognitive radio networks for the purpose of achieving better bandwidth utilization. In existing work on this topic, channel bonding/aggregation is focused on the cases when primary channels are time slotted or stationary as compared with secondary users' activities. In this paper, we analyze the performance of channel bonding/aggregation strategies when primary channels are not time slotted and the time scale of primary activities is at the same level as the secondary users', given that spectrum handover is not allowed. Continuous time Markov chain models are built in order to a…
Channel Occupancy-Based Dynamic Spectrum Leasing in Multichannel CRNs: Strategies and Performance Evaluation
2016
Spectrum leasing has been proposed as an effective approach for enabling more flexible spectrum utilization in CRNs. In CRNs, a primary network (PN) which consists of multiple primary users (PUs) can lease part of the licensed spectrum to secondary users (SUs) in exchange for operational benefits. The focus of this study is to investigate how and to what extent the PN allows spectrum leasing in CRNs, considering the QoS requirements of the PN and the secondary network (SN). Correspondingly, we propose two dynamic spectrum leasing strategies, which can improve the QoS performance of SUs while ensuring sufficient remuneration for PUs. In order to dynamically adjust the portion of leased bandw…
Metal-Oxide-Free Methylammonium Lead Iodide Perovskite-Based Solar Cells: the Influence of Organic Charge Transport Layers
2014
Metal-oxide-free methylammonium lead iodide perovskite-based solar cells are prepared using a dual-source thermal evaporation method. This method leads to high quality reproducible films with large crystal domain sizes allowing for an in depth study of the effect of perovskite film thickness and the nature of the electron and hole blocking layers on the device performance. The power conversion efficiency increases from 4.7% for a device with only an organic electron blocking layer to almost 15% when an organic hole blocking layer is also employed. In addition to the in depth study on small area cells, larger area cells (approx. 1 cm(-2)) are prepared and exhibit efficiencies in excess of 10…