Search results for "Boar"
showing 10 items of 337 documents
Biomarker testing of lung cancer in Spain
2019
Abstract Background Target therapy guide by biomarkers have become the standard of care for patients with lung cancer (LC). So, identify those molecular alterations is one of the most important care needs nowdays. Our objective was to know the implementation degree of these tests in a large cohort of patients in Spain using the Thoracic Tumor Registry (TTR) of the Grupo Espanol de Cancer de Pulmon (Spanish Lung Cancer Group). Methods The TTR is an observational cohort multicenter study of LC in Spain. The study is conducted according to the Declaration of Helsinki and approved by the institutional review board of each participating institute. The registry was approved by the Spanish Drug Ag…
Tobacco use in lung cancer (LC) patients (p) in Spain
2019
Abstract Background Tobacco use, mainly as cigarette smoking, is the leading cause of lung cancer. Eighty-five percent of LC occur in smokers. Understanding the Spanish smoking habits allows the government to design health care policies against this consumption. To do so, the Grupo Espanol de Cancer de Pulmon (Spanish Lung Cancer Group) made this analysis within the context of the Thoracic Tumor Registry (TTR). Methods The TTR is an observational cohort multicenter study in Spain. The study is conducted according to the Declaration of Helsinki and approved by the institutional review board of each participating site. The registry was approved by the Spanish Drug Agency, as a non-post-author…
Tumor Board and Molecular Tumor Board
2021
Specialized expertise and cooperation between different professional figures are increasingly needed for the management of cancer patients. Tumor boards (TB) can address this issue by gathering together different healthcare providers to periodically discuss challenging cases.
The GALAD Score as Potential Screening Test for Hepatocellular Carcinoma in Nonalcoholic Steatohepatitis: An International Multicenter Study
2019
The prevalence of nonalcoholic steatohepatitis (NASH) is rising rapidly and is currently the most common chronic liver disease in Western populations. Hepatocellular carcinoma (HCC) is a major complication of NASH and the current performance of screening approaches based on ultrasound shows limitations. To facilitate earlier diagnosis, this international multicenter study, with eight German and one Japanese center participating, tests the potential benefit of applying the biomarkers AFP, AFP-L3, DCP and related scores for HCC screening in NASH patients. In the retrospective German cohort, 126 NASH patients with newly diagnosed HCC and 231 NASH control patients without HCC were enrolled. In …
Whole-body MRI, FDG-PET/CT, and bone marrow biopsy, for the assessment of bone marrow involvement in patients with newly diagnosed lymphoma
2016
Purpose To compare whole-body MRI (WB-MRI) with diffusion-weighted imaging (DWI), FDG-PET/CT, and bone marrow biopsy (BMB), for the evaluation of bone marrow involvement (BMI) in patients with newly diagnosed lymphoma. Materials and Methods This retrospective study was approved by our Institutional Review Board. Two independent radiologists and one nuclear medicine specialist reviewed all WB-MRI and FDG-PET/CT scans prospectively performed on 104 patients with newly diagnosed lymphoma (53 males; 47 Hodgkin; mean age: 44 years; range, 15–86 years) between 2013 and 2015. The delay between imaging scans and BMBs was up to 10 days. The diagnostic accuracy of WB-MRI (1.5 Tesla MR scanner, with T…
La Red Trampolín: Multinacionales en Latinoamérica
2014
El tema de la casa matriz regional cuenta con cierto nivel de investigación con respecto a las condiciones que inciden en la evolución de una filial, hasta transformarse en casa matriz regional (Bouquet y Birkinshaw, 2008). Dentro de este mismo orden de ideas, ha surgido el fenómeno de la regionalización debido a la creciente necesidad de atender mercados e industrias más maduras (Adler y Hashai, 2007). A pesar de las aproximaciones realizadas al tema, existe una reorganización a nivel regional en diversos contextos que debe ser estudiada a profundidad (Rugman y Verbeke, 2005 y Arregle, Beamish y Hébert, 2009). Esta investigación tiene como objetivo profundizar en los procesos de regionaliz…
Le commissioni di ricorso nel sistema di giustizia dell'Unione europea
2020
Le commissioni di ricorso nel diritto dell’Unione europea sono organi amministrativi, incaricati di risolvere controversie nei settori di competenza degli Uffici, Agenzie ed Autorità presso cui sono strutturate. Esercitano una sicura attività giustiziale, rafforzata dal carattere del loro intervento, che è pregiudiziale rispetto all’ordinaria tutela giurisdizionale. L’interesse per il tema è determinato anche dall’orientamento della giurisprudenza, esaminato nel volume. È invero prevalsa l’interpretazione della c.d. “continuità funzionale”, secondo cui le commissioni di ricorso svolgerebbero la stessa attività degli organi di prima istanza, accentuando gli aspetti amministrativi, a discapit…
Impact of pharmacological and environmental manipulations on neuronal structural plasticity and dynamics
2017
El sistema nervioso de vertebrados es uno de los más estudiados, aunque peor comprendidos, del organismo de mamíferos. Desde que Ramón y Cajal postuló su teoría celular de este sistema (Ramón y Cajal 1909), la neurona se ha postulado como su unidad funcional. Sin embargo, durante las últimas décadas se ha revolucionado la visión que se tenía de éste. Una de las percepciones más asentadas era que, tras el desarrollo embrionario, el sistema nervioso se mantenía inmutable. Sin embargo, ahora sabemos que diferentes formas de plasticidad gobiernan su adaptación, que son necesarias para importantes procesos del día a día, tales como el aprendizaje y la memoria (Smythies 2002; Berlucchi and Buchte…
Multiple directorships of corporate boards and firm performance in India
2017
The purpose of the paper is to investigate, first, the association between multiple directorship assignments (busyness) undertaken by corporate directors and firm performance, second, whether endogenously determined limits of multiple directorships, highlighting the ownership structure and other institutional settings, explain the above association better than those by exogenously mandated by regulators and third, the association between the nature of busyness and firm performance. The study develops measures of busyness in the light of the agency and resource dependence theories. The spline regression technique is applied in order to reflect institutional settings of a large sample and sub…
Do Powerful CEOs Determine Microfinance Performance?
2012
Authors version of an article published in Journal of Management Studies. The definitive version is available from Wiley at: http://dx.doi.org/10.1111/j.1467-6486.2012.01046.x Recently, microfinance has been coming under public and media attacks. The microcredit crisis following from microfinance-induced suicides in 2010 in the Indian state of Andhra Pradesh indicates that weak corporate governance and imprudent risk taking have far-reaching consequences. Yet, analyses of corporate governance mechanisms among microfinance institutions (MFIs) remain underdeveloped. As a response, this study examines the impact of CEO power on MFI risk taking by deriving explicit predictions of this effect fr…