Search results for "Bone Remodeling"
showing 10 items of 164 documents
Metabolic bone disease and osteoporosis in children
2016
To understand the basics of pediatric bone metabolism and mechanisms underlying osteoporosis.
Comment on "Effects of Elastic Resistance Band Exercise on Postural Balance, Estrogen, Bone Metabolism Index, and Muscle Strength of Perimenopausal P…
2017
Investigation of inhibitory effects on EPC-mediated neovascularization by different bisphosphonates for cancer therapy.
2013
Bisphosphonates (BPs) are potent drugs, used in metastatic cancer-like prostate or breast carcinoma. In recent studies, besides reduced bone remodeling, influences on angiogenesis and neovascularization were reported. Since BPs have the tendency to accumulate in the bones, the biological effect of various nitrogen- and non-nitrogen BPs on endothelial progenitor cells (EPCs) that originated from bone marrow and mobilized under physiological and pathophysiological conditions, such as tumor neovascularization, was investigated. EPCs subsequent to 72-h treatment with different concentrations of bisphosphonates comprised the non-nitrogen-containing BP clodronate and the nitrogen-containing BPs i…
Immediate non-submerged implants with laser-microtextured collar placed in the inter-radicular septum of mandibular molar extraction sockets associat…
2019
Background The aim of the present study was to radiographically evaluate the vertical socket walls changes, and the peri-implant marginal bone remodelling, and clinicallly the soft tissues conditions around the non-submerged single implants placed into the inter radicular septum of mandibular molar sockets, associated with a collagen membrane, after 3 years of loading. Material and Methods Thirty patients underwent to placement of a non-submerged implants with a laser-microtextured collar into the inter radicular septum of mandibular molar fresh extraction sockets. A collagen membrane and the mucoperiosteal flap were adapted around the neck of the implants, leaving the laser-microtextured c…
Biological factors involved in alveolar bone regeneration
2019
Background and Aims: To describe the biology of alveolar bone regeneration.Material and Methods: Four comprehensive reviews were performed on (a) mesenchymal cells and differentiation factors leadi ...
The Essential of Bone Histology for Forensic Applications
2019
This chapter illustrates characteristics of bone, as specialized connective tissue, taking into account fundamentals of histology for forensic purposes (Cells of Bone, Concentric or Haversian system, Systems of internal and external circumferential lamellae, Bone Remodeling).
Bone Healing with or without Platelet-Rich Plasma around Four Different Dental Implant Surfaces in Beagle Dogs
2013
Purpose Surface development is one of the major aims in dental implant engineering. Additive application of substances could possibly improve the new bone formation around dental implants. The present study evaluated the bone reaction on four different implant surfaces with or without platelet-rich plasma (PRP). Materials and Methods Four self-tapping titanium screw implants (Branemark MK III [Nobel Biocare, Goteborg, Sweden], Osseotite [3i, Miami, FL, USA], Xive [Densply Friadent, Mannheim, Germany], and Compress [IGfZ eG, Diez, Germany]) with different surfaces were inserted in each hemimandible of 12 female beagle dogs; the implant positions and the application of PRP were randomized. Af…
Anti-resorptive treatment in osteoporosis and their deleterious effects on maxillary bone metabolism in clinical dentistry
2017
Bisphosphonates (BPs) and other antiresorptive agents such as denosumab are widely prescribed for the treatment of osteoporosis and are also used in patients with multiple myeloma and metastatic breast or prostate cancer for avoiding bone reabsorption and fractures that result in increased morbidity–mortality among such individuals. Osteonecrosis of the jaws is an important complication of exposure to BPs or other antiresorptive agents, and although its prevalence is low, it can pose management problems. The definition, diagnosis, and classification of osteonecrosis have evolved since Marx reported the first cases in 2003. The present chapter offers a review and update on the existing diagn…
Cathepsin L in Normal and Pathological Bone Remodeling
2011
Abstract Cathepsin L is a ubiquitous lysosomal cysteine endopeptidase that is mainly involved in the metabolic turnover of intracellular proteins. However, it is now well established that this enzyme may also be implicated in the regulation of other important biological processes includ- ing bone resorption. Therefore, altered expression levels of Cathepsin L may result in disturbances of bone homeo- stasis and, eventually, in the onset of pathological condi- tions associated with altered bone turnover. These observations support the concept that Cathepsin L may be regarded as an additional target for the development of novel therapeutic options for the treatment of patients with bone disea…