Search results for "Boolean model"
showing 10 items of 14 documents
Neuronal Cytoskeleton in Intellectual Disability: From Systems Biology and Modeling to Therapeutic Opportunities
2021
Intellectual disability (ID) is a pathological condition characterized by limited intellectual functioning and adaptive behaviors. It affects 1–3% of the worldwide population, and no pharmacological therapies are currently available. More than 1000 genes have been found mutated in ID patients pointing out that, despite the common phenotype, the genetic bases are highly heterogeneous and apparently unrelated. Bibliomic analysis reveals that ID genes converge onto a few biological modules, including cytoskeleton dynamics, whose regulation depends on Rho GTPases transduction. Genetic variants exert their effects at different levels in a hierarchical arrangement, starting from the molecular lev…
Estimation of fibre orientation from digital images
2001
In this paper, estimation of fibre orientation is studied for fibre systems observable as a blurred greyscale image. The estimation method is based on scaled variograms observed along a set of sampling lines in different directions. The parameters of the orientation distribution are obtained numerically. Simulated data are used to study the statistical properties of the method.
Analysis of Spatially and Temporally Overlapping Events with Application to Image Sequences
2006
Counting spatially and temporally overlapping events in image sequences and estimating their shape-size and duration features are important issues in some applications. We propose a stochastic model, a particular case of the nonisotropic 3D Boolean model, for performing this analysis: the temporal Boolean model. Some probabilistic properties are derived and a methodology for parameter estimation from time-lapse image sequences is proposed using an explicit treatment of the temporal dimension. We estimate the mean number of germs per unit area and time, the mean grain size and the duration distribution. A wide simulation study in order to assess the proposed estimators showed promising resul…
Transience versus recurrence for scale-free spatial networks
2020
Weight-dependent random connection graphs are a class of local network models that combine scale-free degree distribution, small-world properties and clustering. In this paper we discuss recurrence or transience of these graphs, features that are relevant for the performance of search and information diffusion algorithms on the network.
Inclusion ratio based estimator for the mean length of the boolean line segment model with an application to nanocrystalline cellulose
2014
A novel estimator for estimating the mean length of fibres is proposed for censored data observed in square shaped windows. Instead of observing the fibre lengths, we observe the ratio between the intensity estimates of minus-sampling and plus-sampling. It is well-known that both intensity estimators are biased. In the current work, we derive the ratio of these biases as a function of the mean length assuming a Boolean line segment model with exponentially distributed lengths and uniformly distributed directions. Having the observed ratio of the intensity estimators, the inverse of the derived function is suggested as a new estimator for the mean length. For this estimator, an approximation…
Orientational analysis of planar fibre systems observed as a Poisson shot-noise process
2007
Summary We consider two-dimensional fibrous materials observed as a digital greyscale image. The problem addressed is to estimate the orientation distribution of unobservable thin fibres from a greyscale image modelled by a planar Poisson shot-noise process. The classical stereological approach is not straightforward, because the point intensities of thin fibres along sampling lines may not be observable. For such cases, Karkkainen et al. (2001) suggested the use of scaled variograms determined from grey values along sampling lines in several directions. Their method is based on the assumption that the proportion between the scaled variograms and point intensities in all directions of sampl…
Supershape Recovery from 3D Data Sets
2006
In this paper, we apply supershapes and R-functions to surface recovery from 3D data sets. Individual supershapes are separately recovered from a segmented mesh. R-functions are used to perform Boolean operations between the reconstructed parts to obtain a single implicit equation of the reconstructed object that is used to define a global error reconstruction function. We present surface recovery results ranging from single synthetic data to real complex objects involving the composition of several supershapes and holes.
BMaD – A Boolean Matrix Decomposition Framework
2014
Boolean matrix decomposition is a method to obtain a compressed representation of a matrix with Boolean entries. We present a modular framework that unifies several Boolean matrix decomposition algorithms, and provide methods to evaluate their performance. The main advantages of the framework are its modular approach and hence the flexible combination of the steps of a Boolean matrix decomposition and the capability of handling missing values. The framework is licensed under the GPLv3 and can be downloaded freely at http://projects.informatik.uni-mainz.de/bmad.
Studying endocytosis in space and time by means of temporal Boolean models
2006
Endocytosis is a process by which cells carry traffic from the extracellular space into various intracellular compartments. Visualization of fluorescently tagged clathrin proteins (mediators of endocytosis) allows us to image endocytosis in real time. When imaging the plasma membrane, areas of fluorescence generated by different endocytic processes overlap spatially and temporally, forming random clumps. Here, a sequence of segmented clathrin spots is considered a realization of a non-isotropic 3D Boolean model. Estimates of the intensity, the mean perimeter and the density function of the durations of endocytic events are obtained.
Sparse Sampling and Maximum Likelihood Estimation for Boolean Models
1991
A condition for practical independence of contact distribution functions in Boolean models is obtained. This result allows the authors to use maximum likelihcod methods, via sparse sampling, for estimating unknown parameters of an isotropic Boolean model. The second part of this paper is devoted to a simulation study of the proposed method. AMS classification: 60D05