Search results for "Brea"

showing 10 items of 4298 documents

Breast Cancer Incidence in the City and Province of Palermo in 1999-2002: A Breast Cancer Registry Report

2005

: The aim of this study was to assess the incidence of breast cancer in women from the city and province of Palermo (Sicily) in 1999, 2000, 2001, and 2002, using a population-based cancer registry approach. In recent years, a sharp increase of breast cancer incidence has been observed worldwide. Overall, direct age-standardized incidence rates (SIR) were 81.0 per 100,000 person-years, higher in Palermo City (89.4) than in Palermo Province (70.4). Results reported here show a highly significant difference in breast cancer incidence in different areas of Sicily, particularly in the youngest age groups; and a profound difference between the metropolitan area of Palermo and the surrounding area…

AdultRiskPediatricsmedicine.medical_specialtyTime FactorsPopulationBreast NeoplasmsGeneral Biochemistry Genetics and Molecular BiologyBreast cancerHistory and Philosophy of ScienceAge groupsRegistry reportmedicineHumansRegistrieseducationeducation.field_of_studybusiness.industryIncidenceGeneral NeuroscienceIncidence (epidemiology)Significant differenceAge FactorsMiddle Agedmedicine.diseaseMetropolitan areaCancer registryItalyFemalebusinessDemographyAnnals of the New York Academy of Sciences
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Mobilization of peripheral blood progenitor cells (PBPC) in patients undergoing chemotherapy followed by autologous peripheral blood stem cell transp…

1999

We have determined the effect of delayed addition of G-CSF after chemotherapy on PBPC mobilization in a group of 30 patients with high risk breast cancer (HRBC) undergoing standard chemotherapy followed by high-dose chemotherapy (HDCT) and autologous SCT. Patients received FAC chemotherapy every 21 days followed by G-CSF at doses of 5 microg/kg/day starting on day +15 (groups 1 and 2) or +8 (group 3) after chemotherapy. PBPC collections were performed daily starting after 4 doses of G-CSF and continued until more than 2.5 x 10(6) CD34+ cells had been collected. In group 1, steady-state BM progenitors were also harvested and used for SCT. Groups 2 and 3 received PBPC only. The median number …

AdultRiskmedicine.medical_specialtyAdolescentPlatelet Engraftmentmedicine.medical_treatmentCD34UrologyBreast NeoplasmsTransplantation AutologousBreast cancerAntineoplastic Combined Chemotherapy ProtocolsGranulocyte Colony-Stimulating FactorHumansMedicineProgenitor cellTransplantationChemotherapybusiness.industryHematopoietic Stem Cell TransplantationHematologyMiddle Agedmedicine.diseaseHematopoietic Stem Cell MobilizationSurgeryGranulocyte colony-stimulating factorTransplantationFemaleStem cellbusinessBone Marrow Transplantation
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For patients with breast cancer, geographic and social disparities are independent determinants of access to specialized surgeons. A eleven-year popu…

2012

Abstract Background It has been shown in several studies that survival in cancer patients who were operated on by a high-volume surgeon was better. Why then do all patients not benefit from treatment by these experienced surgeons? The aim of our work was to study the hypothesis that in breast cancer, geographical isolation and the socio-economic level have an impact on the likelihood of being treated by a specialized breast-cancer surgeon. Methods All cases of primary invasive breast cancer diagnosed in the Côte d’Or from 1998 to 2008 were included. Individual clinical data and distance to the nearest reference care centre were collected. The Townsend Index of each residence area was calcul…

AdultRural PopulationCancer Researchmedicine.medical_specialtyGeographical isolationBreast Neoplasms[SDV.CAN]Life Sciences [q-bio]/CancerPopulation basedlcsh:RC254-282Health Services Accessibility[ SDV.CAN ] Life Sciences [q-bio]/Cancer03 medical and health sciences0302 clinical medicineBreast cancer[SDV.CAN] Life Sciences [q-bio]/CancerSurgical oncologyGeneticsmedicineHumans030212 general & internal medicineRegistriesHealthcare DisparitiesAgedNeoplasm StagingGynecologybusiness.industryMultilevel modelCancerMiddle Agedlcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogensmedicine.diseasePrognosis3. Good healthsurgical procedures operativeOncologySocioeconomic Factors030220 oncology & carcinogenesisFamily medicineMultilevel AnalysisNeoplasm stagingFemalebusinessRural populationResearch Article
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A study of factors that may influence the determination of copper, iron, and zinc in human milk during sampling and in sample individuals.

1999

The aim of this study was to establish the possible effects of the sampling protocol (between-breast, within-feed, and diurnal differences) and the mother's personal factors (age, parity, iron supplementation, smoking habits, and lactation period) on the copper, iron, and zinc contents in human milk. One hundred thirty-six human milk samples identified by their origin and sampling conditions were analyzed. The samples were obtained from the 2nd to 15th d postpartum from 62 women. The data on the individuals required for the study were available. Mineral determinations were analyzed by flame atomic absorption spectrometry following a standardized protocol. The results showed that iron conten…

AdultSampling protocolEndocrinology Diabetes and MetabolismSample (material)IronClinical Biochemistrychemistry.chemical_elementZincBiochemistryInorganic ChemistryAnimal scienceLactationmedicineHumansBreastMilk HumanChemistryBiochemistry (medical)SmokingSampling (statistics)General MedicineCopperCircadian RhythmZincmedicine.anatomical_structureEnvironmental chemistryDietary SupplementsColostrumFemaleParity (mathematics)CopperBiological trace element research
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Acute abdomen due to endometriosis in a premenopausal woman taking tamoxifen.

2003

Tamoxifen exhibits agonistic properties on the uterus. We describe a premenopausal woman who, while having tamoxifen due to a diagnosis of in situ ductal carcinoma, developed endometriosis requiring surgery.

AdultSelective Estrogen Receptor Modulatorsmedicine.medical_specialtyAntineoplastic Agents HormonalEndometriosisUterusEndometriosisBreast NeoplasmsCarcinomamedicineHumansskin and connective tissue diseasesGynecologybusiness.industryCarcinoma Ductal BreastObstetrics and GynecologyDuctal carcinomamedicine.diseaseAntiestrogenAbdominal PainOvarian CystsTamoxifenmedicine.anatomical_structureReproductive MedicinePremenopauseAcute abdomenAcute DiseaseFemalemedicine.symptombusinesshormones hormone substitutes and hormone antagonistsTamoxifenmedicine.drugEuropean journal of obstetrics, gynecology, and reproductive biology
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Heated breathing tubes affect humidity output of circle absorber systems.

1993

Abstract Study Objective: To verify whether the airway climate in circle systems can be improved with heated breathing tubes. Design: Randomized, controlled, prospective clinical study. Setting: Operating theater of the Department of Maxillofacial Surgery. Patients: 26 adult patients undergoing prolonged anesthesia. Interventions: A total of 26 prolonged anesthetics were conducted in adult patients using a minimal fresh gas flow rate (0.6 L/min) and silicon breathing tubes (16 mm internal diameter) containing a heated coil. Group 1 ( n = 10 patients) was the control group; breathing tubes were unheated. In Group 2 ( n = 10 patients), breathing tubes were heated to 30°C. In Group 3 ( n = 6 p…

AdultSiliconHot TemperatureAbsorptionFlow systemElectric Power SuppliesAnesthesia Closed-CircuitElectric ImpedanceIntubation IntratrachealMedicineHumansProspective StudiesFresh gas flow rateAnestheticsAdult patientsEquipment Safetybusiness.industryTemperatureHumidityHumidityEquipment DesignRespiration ArtificialBreathing tubeAnesthesiology and Pain MedicineAnesthesiaBreathingProspective clinical studybusinessAirwayJournal of clinical anesthesia
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15-prostaglandin dehydrogenase expression alone or in combination with ACSM1 defines a subgroup of the apocrine molecular subtype of breast carcinoma.

2008

Established histopathological criteria divide invasive breast carcinomas into defined groups. Ductal of no specific type and lobular are the two major subtypes accounting for around 75 and 15% of all cases, respectively. The remaining 10% include rarer types such as tubular, cribriform, mucinous, papillary, medullary, metaplastic, and apocrine breast carcinomas. Molecular profiling technologies, on the other hand, subdivide breast tumors into five subtypes, basal-like, luminal A, luminal B, normal breast tissue-like, and ERBB2-positive, that have different prognostic characteristics. An additional subclass termed "molecular apocrine" has recently been described, but these lesions did not ex…

AdultSilver StainingBreast NeoplasmsBiologyProteomicsBiochemistrySubclassAnalytical ChemistryImmunophenotypingCohort StudiesBreast cancerCoenzyme A LigasesmedicineBiomarkers TumorHumansElectrophoresis Gel Two-DimensionalNeoplasm Invasivenessskin and connective tissue diseasesMolecular BiologyAgedAged 80 and overTissue microarrayParaffin EmbeddingApocrineMiddle Agedmedicine.diseaseImmunohistochemistryApocrine GlandsPhenotypeTissue Array AnalysisImmunologyCancer researchDisease ProgressionHydroxyprostaglandin DehydrogenasesImmunohistochemistryFemaleApocrine CellBreast carcinomaMolecularcellular proteomics : MCP
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Management of pharyngeal collapse in patients affected by moderate obstructive sleep apnoea syndrome

2022

This study reports our experience in a selected cohort of patients affected by mild-moderate OSAS, without tonsillar obstruction, and treated with pharyngoplasty.In a case-control retrospective study, we compared modified expansion sphincter pharyngoplasty (MESP) to modified barbed reposition pharyngoplasty (MBRP) in adult patients with oropharyngeal transversal collapse with a BMI ≤ 30 kg/mWe enrolled 20 patients: 10 treated with MESP and 10 treated with MBRP. Mean apnoea-hypoapnoea index (AHI) was 22.8 (± 5.63). We observed in both groups a significant reduction of AHI and oropharyngeal obstruction (p = 0.01), with a success rate, according with Sher's criteria, of 90% for MESP and 80% fo…

AdultSleep Apnea Obstructivesoft palatePolysomnographySnoringPlastic Surgery ProceduresCohort StudiesTreatment OutcomeGeneral EnergyOtorhinolaryngologyCase-Control StudiesHumansPharynxsleep-disorderedbreathingobstructive sleep apnoea hypopnoea syndromeRetrospective StudiesActa Otorhinolaryngologica Italica
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Airway cells after swimming outdoors or in the sea in nonasthmatic athletes

2003

BONSIGNORE, M. R., G. MORICI, L. RICCOBONO, M. PROFITA, A. BONANNO, A. PATERNO, R. DI GIORGI, L. CHIMENTI, P. ABATE, F. MIRABELLA, A. M. VIGNOLA, and G. BONSIGNORE. Airway Cells after Swimming Outdoors or in the Sea in Nonasthmatic Athletes. Med. Sci. Sports Exerc., Vol. 35, No. 7, pp. 1146–1152, 2003. Marathon runners and elite swimmers showed increased inflammatory cells in the airways at baseline. Although airway neutrophils increase further after a marathon race, the airway response to swimming is unknown. The aim of this study was to assess the effects of swimming on airway cells. To avoid the concomitant effects of chronic exposure to chlorine, the study was conducted in seven nonasth…

AdultSpirometrymedicine.medical_specialtyAdolescentRespiratory SystemPhysical Therapy Sports Therapy and RehabilitationNitric OxideNeutrophil ActivationRunningEndurance trainingInternal medicinemedicineHumansOrthopedics and Sports MedicineExpirationRespiratory systemSwimmingInflammationEosinophil cationic proteinmedicine.diagnostic_testbusiness.industryrespiratory systemEosinophilRespiratory Function Testsrespiratory tract diseasesSurgerymedicine.anatomical_structureEndocrinologyBreath TestsExhaled nitric oxidePhysical EndurancebusinessAirway
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Does Conservative Surgery for Breast Carcinoma Still Require Axillary Lymph Node Evaluation? A Retrospective Analysis of 1156 Consecutive Women With …

2016

Abstract Background The role of axillary surgery for early breast carcinoma treated with conservative surgery and radiotherapy is currently the subject of considerable investigation. Recent studies have supported the noninferiority of avoiding axillary surgery in terms of overall survival when sentinel lymph node biopsy (SLNB) presents ≤ 2 positive lymph nodes, thus sparing the patients from complications. There are some ongoing studies investigating the possibility of omitting SLNB. Axillary study seems to be sufficiently replaced by SLNB for staging the disease. Axillary surgery maintains a therapeutic role in the presence of > 2 metastatic lymph nodes at SLNB. Patients and Methods We per…

AdultT1 tumorsCancer Researchmedicine.medical_specialtymedicine.medical_treatmentSentinel lymph nodePopulationBreast Neoplasms030230 surgeryConservative Treatment03 medical and health sciences0302 clinical medicineBreast cancerAxillary lymph node dissectionmedicineHumansMore than two metastatic axillary lymph nodeeducationLymph nodeAgedNeoplasm StagingRetrospective StudiesAged 80 and overeducation.field_of_studybusiness.industrySentinel Lymph Node BiopsyAxillary Lymph Node DissectionAxillary lymph node dissection; More than two metastatic axillary lymph nodes; Not axillary surgery staging; Sentinel lymph node biopsy; T1 tumorsMiddle Agedmedicine.diseaseSurgeryRadiation therapymedicine.anatomical_structureOncology030220 oncology & carcinogenesisLymphatic MetastasisAxillaLymph Node ExcisionNot axillary surgery stagingFemaleRadiotherapy AdjuvantLymphSentinel Lymph NodeBreast carcinomabusinessClinical breast cancer
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