Search results for "Breed"
showing 10 items of 697 documents
A trade-off between sexual signalling and immune function in a natural population of the drumming wolf spider Hygrolycosa rubrofasciata.
2005
The field of ecological immunology is ultimately seeking to address the question ‘Why is there variation in immune function?’ Here, we provide experimental evidence that costs of ubiquitous sexual signals are a significant source of variation in immune function. In the mating season, males of the wolf spider Hygrolycosa rubrofasciata drum against dry leaves while wandering around the habitat searching for receptive females. According to a previous study, the male metabolic rate during the drumming increases 22-fold compared to the resting metabolic rate. In the present study, we examined whether investment in costly courtship drumming decreases male immune function in a wild population of H…
Lipoprotein lipase-facilitated uptake of LDL is mediated by the LDL receptor
2007
LPL mediates the uptake of lipoproteins into different cell types independent of its catalytic activity. The mechanism of this process and its physiological relevance are not clear. Taking into account the importance of the endothelial barrier for lipoprotein uptake, in vitro studies with primary aortic endothelial cells from wild-type and low density lipoprotein receptor (LDLR)-deficient (LDLR(-/-)) mice were performed. Addition of LPL almost doubled the uptake of LDL into wild-type cells. However, there was virtually no LPL-mediated change of LDL uptake into LDLR(-/-) cells. Upregulation of LDLR by lipoprotein-deficient serum/lovastatin in wild-type cells resulted in a 7-fold increase of …
Analysis of the thermo-mechanical behaviour of the DEMO Water-Cooled Lithium Lead breeding blanket module under normal operation steady state conditi…
2015
Within the framework of DEMO R&D activities, a research cooperation has been launched between ENEA, the University of Palermo and CEA to investigate the thermo-mechanical behaviour of the outboard equatorial module of the DEMO1 Water-Cooled Lithium Lead (WCLL) blanket under normal operation steady state scenario. The research campaign has been carried out following a theoretical-computational approach based on the Finite Element Method (FEM) and adopting a qualified commercial FEM code. In particular, two different 3D FEM models (Model 1 and Model 2), reproducing respectively the central and the lateral poloidal-radial slices of the WCLL blanket module, have been set up. A particular attent…
On the thermal and thermomechanical assessment of the “Optimized Conservative” helium-cooled lithium lead breeding blanket concept for DEMO
2018
Abstract Within the framework of EUROfusion R&D activities a research campaign has been performed at CEA-Saclay, in close collaboration with the University of Palermo, in order to investigate thermal and thermomechanical performances of the “Optimized Conservative” concept of DEMO Helium-Cooled Lithium Lead breeding blanket (HCLL). Attention has been paid to the HCLL outboard equatorial module (OEM) when subjected to the steady state nominal loading scenario. To this purpose three simplified 3D models, characterized by an increasing level of detail, have been set-up taking into account, firstly, a single radial-toroidal slice, then a basic module geometric unity composed by two adjacent sli…
Characterisation and radiolysis of modified lithium orthosilicate pebbles with noble metal impurities
2017
Modified lithium orthosilicate (Li4SiO4) pebbles with additions of titanium dioxide (TiO2) are suggested as an alternative tritium breeding ceramic for the European solid breeder test blanket module. The noble metals – platinum (Pt), gold (Au) and rhodium (Rh), can be introduced into the modified Li4SiO4 pebbles during the melt-based process, due to the corrosion of Pt-Rh and Pt-Au alloy crucible components. In this study, the surface microstructure, chemical and phase composition of the modified Li4SiO4 pebbles with different contents of the noble metals was analysed. The influence of the noble metals on the radiolysis was evaluated after irradiation with accelerated electrons (E = 5 MeV),…
Influence of chemisorption products of carbon dioxide and water vapour on radiolysis of tritium breeder
2014
Abstract Lithium orthosilicate pebbles with 2.5 wt% excess of silica are the reference tritium breeding material for the European solid breeder test blanket modules. On the surface of the pebbles chemisorption products of carbon dioxide and water vapour (lithium carbonate and hydroxide) may accumulate during the fabrication process. In this study the influence of the chemisorption products on radiolysis of the pebbles was investigated. Using nanosized lithium orthosilicate powders, factors, which can influence the formation and radiolysis of the chemisorption products, were determined and described as well. The formation of radiation-induced defects and radiolysis products was studied with …
Thermal optimization of the Helium-Cooled Lithium Lead breeding zone layout design regarding TBR enhancement
2017
Abstract Within the framework of EUROfusion R&D activities, CEA-Saclay has carried out an investigation of the thermal and mechanical performances of alternative designs intended to enhance the Tritium Breeding Ratio (TBR) of the Helium-Cooled Lithium Lead (HCLL) Breeding Blanket (BB) for DEMO. Neutronic calculations performed on the 2014 DEMO HCLL baseline predicted a value of TBR equal to 1.07, lower than the required value of 1.1, necessary to ensure the tritium self-sufficiency of the breeding blanket taking into account uncertainties. In order to reach the TBR target, the strategy of the steel amount reduction inside the HCLL module breeding zone (BZ) has been followed by suppressing s…
On the effect of stiffening plates configuration on the DEMO Water Cooled Lithium Lead Breeding Blanket module thermo-mechanical behaviour
2019
Abstract Within the framework of the pre-conceptual design of the EU-DEMO Breeding Blanket (BB) supported by EUROfusion action, results of the research activities carried out in the last years have highlighted that changes in the proposed Water Cooled Lithium Lead (WCLL) BB design have to be considered, especially as to the liquid breeder circulation path within the BB module. Therefore, in view of the definition of a final WCLL BB module layout, a parametric campaign of numerical analyses has been carried out at the University of Palermo in order to assess the impact of different SPs configurations on the module thermo-mechanical performances. To this purpose, attention has been focussed o…
Modelling of the thermal mechanical behaviour of a single size beryllium pebble bed
2001
The Helium Cooled Pebble Bed (HCPB) Blanket for fusion power reactors and the ITER breeding blanket are based on the use of pebble beds of lithium ceramics as breeder and beryllium as neutron multiplier. Experimental activities were performed at Forschungszentrum Karlsruhe concerning the measurement of pebble bed heat transfer parameters. At the Department of Nuclear Engineering of the University of Palermo, the experimental results have been reproduced by means of the ABAQUS finite element code. Moreover, a thermal-mechanical theoretical model has been developed for single size beryllium pebble beds. In the paper the results from the numerical and theoretical analyses and the comparison wi…
Thermo-mechanical analyses and ways of optimization of the helium cooled DEMO First Wall under RCC-MRx rules
2017
Abstract The EUROfusion Consortium develops a design of a fusion power demonstrator plant (DEMO) in the framework of the European “Horizon 2020” innovation and research program. One of the key components in the fusion reactor is the Breeding Blanket (BB) surrounding the plasma, ensuring tritium self-sufficiency, heat removal for conversion into electricity, and neutron shielding. Among the 4 candidates for the DEMO BB, 2 of them use helium as coolant (HCPB, HCLL), and another one (DCLL) uses helium to cool down the First Wall (FW) only. Due to uncertainties regarding the plasma Heat Flux (HF) load the DEMO BB integrated FW will have to cope with, a set of sensitive thermal and stress analys…