Search results for "C2"

showing 10 items of 879 documents

A Paravermal Trans-Cerebellar Approach to the Posterior Fossa Tumor Causes Hypertrophic Olivary Degeneration by Dentate Nucleus Injury

2021

Background: In brain tumor surgery, injury to cerebellar connectivity pathways can induce a neurodegenerative disease called hypertrophic olivary degeneration (HOD), along with a disabling clinical syndrome. In children, cerebellar mutism syndrome (CMS) is another consequence of damage to cerebello&ndash

EpendymomaCancer Researchmedicine.medical_specialtyCerebellumcerebellumPosterior fossamedulloblastomalcsh:RC254-282ArticleHOD03 medical and health sciences0302 clinical medicineMedicineneurosurgeryMedulloblastomaPilocytic astrocytomabusiness.industryCMSOlivary degenerationmedicine.diseaselcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogensmedicine.anatomical_structureDentate nucleusOncology030220 oncology & carcinogenesisRadiologyNeurosurgerybusiness030217 neurology & neurosurgerycerebellar mutismCancers
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The first European interdisciplinary ewing sarcoma research summit.

2012

This is an open-access article distributed under the terms of the Creative Commons Attribution Non Commercial License.-- et al.

EpigenomicsCancer ResearchAlternative medicineMedizinComputingMilieux_LEGALASPECTSOFCOMPUTINGReview ArticleBioinformatics[SDV.BBM.BM] Life Sciences [q-bio]/Biochemistry Molecular Biology/Molecular biologydrug screen0302 clinical medicineDrug screenCancer genomicssignallingSarcomagenesis0303 health sciencessarcomagenesisSummitgeography.geographical_feature_categoryOpinion leadershipGenomicsLaboratory resultslcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogensPrognosisanimal models3. Good healthAnimal modelsMetastatic Ewing SarcomaOncology030220 oncology & carcinogenesis[SDV.BBM.GTP] Life Sciences [q-bio]/Biochemistry Molecular Biology/Genomics [q-bio.GN]EpigeneticsSarcomaImmunotherapyPrioritizationmedicine.medical_specialty[SDV.CAN]Life Sciences [q-bio]/Cancerlcsh:RC254-28203 medical and health sciences[SDV.CAN] Life Sciences [q-bio]/Cancer[SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry Molecular Biology/Genomics [q-bio.GN]medicinegenomics030304 developmental biologyMedical educationgeographyepigeneticsbusiness.industrybiomarkers[SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry Molecular Biology/Molecular biologymedicine.diseaseClinical trialprognosisbusinessBiomarkersEwing sarcomaFrontiers in oncology
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Extensive molecular analysis of patients bearing CFTR-related disorders.

2012

Cystic fibrosis transmembrane conductance regulator (CFTR)–related disorders (CFTR-RDs) may present with pancreatic sufficiency, normal sweat test results, and better outcome. The detection rate of mutations is lower in CFTR-RD than in classic CF: mutations may be located in genes encoding proteins that interact with CFTR or support channel activity. We tested the whole CFTR coding regions in 99 CFTR-RD patients, looking for gene mutations in solute carrier (SLC) 26A and in epithelial Na channel (ENaC) in 33 patients who had unidentified mutations. CFTR analysis revealed 28 mutations, some of which are rare. Of these mutations, RT-PCR demonstrated that the novel 1525-1delG impairs exon 10 s…

Epithelial sodium channelcongenital hereditary and neonatal diseases and abnormalitiesCystic fibrosis CFTR SLC26A SCNNCystic FibrosisAnion Transport ProteinsDNA Mutational Analysismolecular analysiCystic Fibrosis Transmembrane Conductance RegulatorGene mutationPathology and Forensic Medicinecongenital bilateral absence of vasa deferentesExonGene Frequencydisseminated bronchiectasiscongenital bilateral absence of vasa deferenteHumansTrypsinmolecular analysisEpithelial Sodium ChannelsGeneCells CulturedGenetic Association StudiesGeneticsbiologydisseminated bronchiectasiEpithelial Cellsrespiratory systemrecurrent pancreatitidigestive system diseasesCystic fibrosis transmembrane conductance regulatorrespiratory tract diseasesSolute carrier familyCFTR related disordersTrypsin Inhibitor Kazal PancreaticCase-Control StudiesRNA splicingMutationbiology.proteinMolecular MedicineCFTR related disorderSLC26 familyCarrier ProteinsNa channel ENaCMinigenerecurrent pancreatitis
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Clinical microbeam radiation therapy with a compact source: specifications of the line-focus X-ray tube

2020

Highlights • Line-focus X-ray tubes are suitable for clinical microbeam radiation therapy (MRT). • A modular high-voltage supply safely enables high electron beam powers. • An electron accelerator was designed to generate an eccentric focal spot. • We simulated a peak-to-valley dose ratio above 20 for single-field MRT. • Microbeam arc therapy spares healthy brain tissue compared to single-field MRT.

Equivalent uniform doselcsh:Medical physics. Medical radiology. Nuclear medicineMaterials scienceCompact radiation sourcelcsh:R895-920Monte Carlo methodElectronlcsh:RC254-282030218 nuclear medicine & medical imaginglaw.inventionCompact Radiation Source ; Equivalent Uniform Dose ; Line-focus X-ray Tube ; Microbeam Arc Therapy ; Microbeam Radiation Therapy ; Modular High-voltage Supply03 medical and health sciences0302 clinical medicineOpticslawRadiology Nuclear Medicine and imagingFocal Spot SizeOriginal Research ArticleLine-focus X-ray tubeRange (particle radiation)Radiationbusiness.industryMicrobeam arc therapyMicrobeamHot cathodeModular high-voltage supplyX-ray tubeequipment and supplieslcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens030220 oncology & carcinogenesisCathode raybusinessMicrobeam radiation therapyPhysics and Imaging in Radiation Oncology
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Who cares? Evidence on informal and formal home care use in Estonia

2019

Despite increasing attention to long-term care (LTC) and related challenges in the Estonian social policy agenda, the distributional fairness of LTC services in the country has received very limited attention. Using SHARE data, we address informal and formal home care services and identify the socio-economic factors that drive or hinder their use among the Estonian elderly. The relationship between informal and formal home care utilization is estimated applying the new approach to instrumental variable method proposed by Lewbel [2012. Using heteroscedasticity to identify and estimate mismeasured and endogenous regressor models. Journal of Business and Economic Statistics, 30(1), 67–80]. We …

EstoniaEconomic growthlcsh:K4430-4675lcsh:HD72-88lcsh:Economic growth development planningPolitical science0502 economics and businessddc:330050207 economicslcsh:Public financeSocial policyJ14050208 financeI18I11I1205 social sciencesformal home careEstonianlanguage.human_languageinformal careLong-term carePolitical Science and International RelationslanguageSHARElong-term careC25C26General Economics Econometrics and Finance
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R&D Offshoring and the Productivity Growth of European Regions

2013

The recent increase in R&D offshoring have raised fears that knowledge and competitiveness in advanced countries may be at risk of `hollowing out\'. At the same time, economic research has stressed that this process is also likely to allow some reverse technology transfer and foster growth at home. This paper addresses this issue by investigating the extent to which R&D offshoring is associated with productivity dynamics of European regions. We find that offshoring regions have higher productivity growth, but this positive effect fades down with the number of investment projects carried out abroad. A large and positive correlation emerge between the extent of R&D offshoring and the home reg…

Europe; Foreign investments; R&D offshoring; Regional productivity;Strategy and Managementjel:C23International tradeManagement Science and Operations ResearchPositive correlationjel:F23Management of Technology and Innovation0502 economics and businessEconomicsEconomic geographyForeign investments050207 economicsjel:O47ProductivityEconomic researchOffshoringbusiness.industry05 social sciencesInvestment (macroeconomics)Europejel:O52R&D O shoring Regional Productivity Foreign Investments EuropeR&D offshoring8. Economic growthTechnology transferR&D Offshoring; Regional Productivity; Foreign Investments; EuropeRegional productivityjel:R11business050203 business & management
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Modeling temporal treatment effects with zero inflated semi-parametric regression models: The case of local development policies in France

2017

International audience; A semi-parametric approach is proposed to estimate the variation along time of the effects of two distinct public policies that were devoted to boost rural development in France over a similar period of time. At a micro data level, it is often observed that the dependent variable, such as local employment, does not vary along time, so that we face a kind of zero inflated phenomenon that cannot be dealt with a continuous response model. We introduce a conditional mixture model which combines a mass at zero and a continuous response. The suggested zero inflated semi-parametric statistical approach relies on the flexibility and modularity of additive models with the abi…

FOS: Computer and information sciencesEconomics and EconometricsLocal Developmentsemiparametric regressiondifferencePublic policyselection01 natural sciencesStatistics - Applicationslocal developmentpanel data010104 statistics & probabilityEconomica0502 economics and businessEconometricsApplications (stat.AP)0101 mathematics[MATH]Mathematics [math]Additive modelsemi-parametric regressionenterprise zonespropensity scoreJEL Classification: C14 C23 C54 O18050205 econometrics Mathematicsinferencesmoothing parametertemporal effects05 social sciencesSH1_2SH1_6multiple treatmentspolicy evaluation[SHS.ECO]Humanities and Social Sciences/Economics and FinanceZero (linguistics)Rural developmentVariation (linguistics)asymptoticsmixture of distributionsSemi parametric regressionAdditive modelsPanel dataAdditive models; local development; mixture of distributions; multiple treatments; panel data; policy evaluation; semiparametric regression; temporal effects
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The infinite dihedral group

2022

We describe the infinite dihedral group as automaton group. We collect basic results and give full proofs in details for all statements.

FOS: Mathematics20F65 (Primary) 05C25 20E08 68Q70 13F25 (Secondary)Computer Science::Symbolic ComputationGroup Theory (math.GR)Nonlinear Sciences::Cellular Automata and Lattice GasesMathematics - Group TheoryComputer Science::Formal Languages and Automata Theory
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Aperiodic chain recurrence classes of $C^1$-generic diffeomorphisms

2022

We consider the space of $C^1$-diffeomorphims equipped with the $C^1$-topology on a three dimensional closed manifold. It is known that there are open sets in which $C^1$-generic diffeomorphisms display uncountably many chain recurrences classes, while only countably many of them may contain periodic orbits. The classes without periodic orbits, called aperiodic classes, are the main subject of this paper. The aim of the paper is to show that aperiodic classes of $C^1$-generic diffeomorphisms can exhibit a variety of topological properties. More specifically, there are $C^1$-generic diffeomorphisms with (1) minimal expansive aperiodic classes, (2) minimal but non-uniquely ergodic aperiodic c…

FOS: Mathematics[MATH.MATH-DS] Mathematics [math]/Dynamical Systems [math.DS]Dynamical Systems (math.DS)Mathematics - Dynamical Systems37C20 37D30 57M30
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An approach to electromagnetism from the general relativity

2010

Classical gravitation is so similar to the electrostatic that the possible unification has been investigated for many years. Although electromagnetism is formulated successfully by quantum field theory, this paper proposes a simple approach to describe the electromagnetism from the macroscopic perspective of general relativity. The hypothesis is based on two charged particles that cause disturbance energy sufficient to disrupt the space-time and explain approximately Maxwell's equations. Therefore, with such this simple idea, we suggest the possibility that the geometric relationship between electromagnetism and gravitation is not yet fully exhausted.

FOS: Physical sciences31E05 81V10 81V17 81V22 83C22 83C50General Relativity and Quantum Cosmology (gr-qc)General Relativity and Quantum Cosmology
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