Search results for "CAI"

showing 10 items of 579 documents

il CAI modula l'espressione di Bcr-Abl tramite l'aumento dei Ros in cellule di leucemia mieloide cronica Imatinib-resistenti

2009

La leucemia mieloide cronica (LMC) è una neoplasia causata da una traslocazione reciproca non bilanciata tra il braccio lungo del cromosoma 9 e quello del cromosoma 22. Tale traslocazione determina la formazione dell’oncogene di fusione bcr-abl codificante per un’oncoproteina con attività tirosin-chinasica costitutiva. Le conoscenze dei meccanismi molecolari alla base della neoplasia, acquisite negli ultimi anni, hanno permesso di sviluppare terapie volte all’inibizione dell’attività chinasica della chimera BCR-ABL. Tra queste, l’imatinib mesilato (IM), inibitore selettivo della protein chinasi, ha rivoluzionato le terapie per la LMC. Sebbene numerosi pazienti in fase cronica, trattati con …

imatinib-resistanceSettore BIO/13 - Biologia ApplicataCAI
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Les organisations publiques : des institutions communicantes ? Le cas des Caisses d'Allocations Familiales

2009

L’objectif de cet article est de proposer une approche comprehensive de la communication des organisations publiques a travers le cas des Caisses d’Allocations Familiales (CAF). Les travaux dont il est issu ont eu pour objet d’interroger les representations des cadres, charges de communication et directeurs des CAF autour de la notion d’institution communicante. Il s’agit notamment de preciser si celle-ci releve d’un artefact ou pourrait -et a quelles conditions- constituer un modele valide pour analyser la communication des organisations publiques.

institution communicante organisations publiques caisses d'allocations familiales approche communicationnelle représentations des cadres[SHS.GESTION]Humanities and Social Sciences/Business administrationGeneral Medicine[SHS.GESTION] Humanities and Social Sciences/Business administration[ SHS.GESTION ] Humanities and Social Sciences/Business administration
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Il diritto non scritto nel sistema della Convenzione europea dei diritti umani

2016

Il lavoro si occupa dei rapporti tra diritto internazionale generale e sistema della Cedu, affrontando in particolare il problema di capire se la Corte edu abbia fatto ricorso al modello tradizionalmente usato nella giurisprudenza internazionale per stabilire condizioni e modalità di funzionamento delle norme generali nel sistema o se abbia elaborato una concezione un modello autonomo. This paper discusses the relationship between customary international law and the ECHR. The focus is the question whether this problem has been handled by the European Court of Human Rights through the model of relationship between customary law and treaty law which is commonly used by international judges an…

international law - customary law - ECHR - relationship between customary law and treaties - interpretation in conformity with customary law - integral application of customary law - autonomous interpretation method - balancing conflicting values.diritto internazionale - diritto consuetudinario - Cedu - rapporti tra norme - presunzione di conformità al diritto consuetudinario - principio di integriale applicaizone del diritto consuetudinario - interpretazione autonoma - bilanciamento.Settore IUS/13 - Diritto Internazionale
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La negation et l'interrogation dans un corpus de test oral-francais langue etrangere

1998

interrogationnégationfrancais parlétesting de la compétence oralefrancais langue étrangèrequestion
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Exposer l’Amérique. Sim Copans à la Radio Française (1946 – 1954)

2021

National audience

jazz[SHS.HIST] Humanities and Social Sciences/Historymusique américaine[SHS.ART] Humanities and Social Sciences/Art and art historyémissions radiophoniquesaudiovisuel[SHS.ART]Humanities and Social Sciences/Art and art history[SHS.HIST]Humanities and Social Sciences/HistorySim CopansComputingMilieux_MISCELLANEOUS
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Antinociceptive Effects of Turkish Endemic Eryngium kotschyi Boiss. Roots by Bioactivity Guided Fractionation

2010

Eryngium species (Apiaceae) are well known plants in ethnobotanical culture throughout world and also in Turkey. They are used as antitussive, diuretic as well as for analgesic and antiinflammatory purposes in traditional medicine. This study aimed to evaluate the antinociceptive activity of endemic Eryngium kotschyi Boiss. root extracts by bioguided fractionation. The antinociceptive activity of the extracts/fractions/compound was studied in mice using acetic acid induced writhing test and and hot plate test. The methanolic extract was sequentially partitioned with hexane, dichloromethane and water saturated n-butanol. Among the fractions, the n-BuOH fraction showed the most significant re…

lcsh:Chemistrylcsh:QD241-441Eryngium kotschyilcsh:QD1-999lcsh:Organic chemistrylcsh:BotanyErdem S. A. ARIHAN O. MITAINE-OFFER A. İSKİT A. B. Kartal M. LACAILLE-DUBOIS M. -Antinociceptive Effects of Turkish Endemic Eryngium kotschyi Boiss. Roots by Bioactivity Guided Fractionation- RECORDS OF NATURAL PRODUCTS cilt.10 ss.168-175 2016fractionationtriterpene saponinantinociceptiveApiaceaelcsh:QK1-989
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Experimental test on the use of MS-222 for ostracod anaesthesia: concentration, immersion period and recovery time

2010

Anaesthesia of animals may be useful for different purposes, particularly for veterinary reasons or in experimental research, for manipulation or treatment of immobilized but alive animals. Its use in crustaceans is not uncommon, but it has never been described for Ostracoda. We provide brief and preliminary guidelines on the use of the tricaine mesylate (MS-222) on the widespread freshwater ostracod Eucypris virens and we show that this compound is an effective anaesthetic used as a bath treatment at minimum concentrations of 500 mg L-1. This value is considerably higher than that recommended for other aquatic animals like fish. Recovery time, ranging from 5 to 15 minutes, is mostly determ…

lcsh:GE1-350Tricaine mesylateEcologybiologyEucypris virens Crustacea tricaine mesylate sedation surgery markinglcsh:Geography. Anthropology. RecreationAquatic animalAquatic Sciencebiology.organism_classificationImage captureExperimental researchchemistry.chemical_compoundchemistryEucypris virenslcsh:GAnesthesiaOstracodImmersion (virtual reality)lcsh:GB3-5030lcsh:Physical geographylcsh:Environmental sciencesWater Science and TechnologyJournal of Limnology
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Arte da Linguagem na Era da Panofonia

2018

This article calls attention to the hybrid genre of voice-based performances and its blending of the supposed binaries of human and machinic speech. Using the concept of panophonia, the author refers to the animatronic sculptures of speaking figures created by Ken Feingold and to Mark Böhlen’s talking robots. Through their comparative analysis, the author explores different poetic metalanguages both artists create to deconstruct communicative structures that demarcate post-human era.

lcsh:Language and Literaturesíntese de falamedia_common.quotation_subjectMark Böhlenlcsh:Literature (General)Speech synthesiscomputer.software_genrepanphoniaauraturaVisual artsKen Feingoldspeech synthesissynthetic voicepanofoniamedia_commonvoz sintéticaLanguage artsSculpturePoetryperformances vocaisArtlcsh:PN1-6790voice-based performancesauraturelcsh:PcomputerMatLit : Materialidades da Literatura
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Che cosa significa parlare a vuoto? Aristotele, il linguaggio e la logica arcaica

2004

linguaggio logica arcaica aristotele significazione nome frase
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Friday Black et Intruders : lecture croisée au prisme de l'afrofuturisme

2022

This article contrasts “The Finkelstein 5” and “Zimmer Land”, from Nana Kwame Adjei Brenyah’s short story collection Friday Black (2018) with the “Untitled” series from Mohale Mashigo’s Intruders (2018), using Mark Dery’s definition of Afrofuturism as a reading grid and a starting point. While both collections draw on the codes of science fiction and dystopia to portray racialized characters in futuristic settings to examine their relation to technology and their place in fictional ‘future’ societies, they take on different approaches. The article concludes that Adjei-Brenyah’s writing, in Friday Black, leans towards what could be termed ‘Afropresentism’ based on François Hartog’s definitio…

littérature sud-africaine[SHS.LITT] Humanities and Social Sciences/Literatureshort story collectionAfrican American literatureAfrofuturismereceuil de nouvellesAfrofuturism[SHS] Humanities and Social Sciencesspeculative fictionSouth African literaturefiction spéculativelittérature afro-américaine
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