Search results for "CALL"

Vaccination with ENO1 DNA Prolongs Survival of Genetically Engineered Mice with Pancreatic Cancer

2013

Background & Aims Pancreatic ductal adenocarcinoma (PDA) is an aggressive tumor, and patients typically present with late-stage disease; rates of 5-year survival after pancreaticoduodenectomy are low. Antibodies against α-enolase (ENO1), a glycolytic enzyme, are detected in more than 60% of patients with PDA, and ENO1-specific T cells inhibit the growth of human pancreatic xenograft tumors in mice. We investigated whether an ENO1 DNA vaccine elicits antitumor immune responses and prolongs survival of mice that spontaneously develop autochthonous, lethal pancreatic carcinomas. Methods We injected and electroporated a plasmid encoding ENO1 (or a control plasmid) into Kras G12D /Cre (KC) mice …

More about genetically modified tumour vaccines

1998

SenseCam: A new tool for memory rehabilitation?

2016

International audience; The emergence of life-logging technologies has led neuropsychologist to focus on understanding how this new technology could help patients with memory disorders. Despite the growing number of studies using life-logging technologies, a theoretical framework supporting its effectiveness is lacking. This review focuses on the use of life-logging in the context of memory rehabilitation, particularly the use of SenseCam, a wearable camera allowing passive image capture. In our opinion, reviewing SenseCam images can be effective for memory rehabilitation only if it provides more than an assessment of prior occurrence in ways that reinstates previous thoughts, feelings and …

Microftalmia monolaterale ed agenesia del corpo calloso in un neonato con sindrome MLS/MIDAS da delezione Xpcoinvolgente il gene della olocitocromoc-…

2012

The Transcallosal Anterior Interfoniceal Approach: A Microsurgical Anatomy Study

2014

Objectives: A plethora of surgical strategies have been described to reach deeply lesions situated within the third ventricle, including the Rosenfeld or anterior transcallosal interfoniceal approach (TAIF). Firstly, introduced in 2001, it consists of a small callosotomy followed by the midline transseptal dissection of fornices to enter the roof of the third ventricle. The aim of this microsurgical anatomy study is to describe and show each stage of the surgical procedure, focusing on the possible trajectories to anatomic landmarks. Participants: A total of twenty adult cadaveric specimens were used in this study. Using x3 to x40 magnifications the surgical dissection was carried out in a …

Electoronic Performance Monitoring in Call Centers: An Ethical Decision Model

2013

Ever since it emerged on a widespread basis in the 1990s, electronic performance monitoring of employees has received significant scrutiny in the literature. Call centers have been the focus of many of these studies. This particular study addresses the issue of electronic performance monitoring in call centers from an ethical perspective. The following ethical dilemma is offered: "Is it ethical for a call center manager to evaluate the performance of a call center employee using electronic performance monitoring data gathered on the employee?" Using utilitarian, Kantian, virtue, and covenantal ethical theories, the study proposes an ethical decision model and subsequently applies the model …

Śmierć, nieobecność i samotność - motyw traumatyzującej utraty matki w zbiorze opowiadań Lejli Kalamujić "Zovite me Esteban"

2019

Lejla Kalamujić (bom 1980) is a Bosnian writer from Sarajevo and the author of two collections of stories: Anatomy of a Smile (2009) and Call me Esteban (2015). The paper presents the autobiographical stories collected in the second book, in which the most important theme is death, especially the premature death of a mother. The aim of the article is to show the motive of the loss of a mother. The writer uses first-person narration and the protagonist is a woman named Lejla, a type of alter ego for her. The stories are written from different points of view and from different time perspectives. The intertextual themes in the book are the most interesting ones and have real artistic value (th…

Female Oviposition Decisions and Their Impact on Progeny Life-History Traits

2008

An important factor affecting the life-history of an organism is parental investment in reproduction: reproductive decisions are almost invariably costly. Therefore, reproductive decisions should be beneficial in terms of increased offspring number or fitness. For example, egg laying decisions in many insects can influence resource availability of the offspring through changes in the larval density, and resource availability will have effects on many life-history traits. Here we studied whether female reproductive decisions affect offspring fitness in Callosobruchus maculatus seed beetles. Females laid more eggs on black-eye beans than on mung beans. However, when the difference in the surf…

Hyperplastic callus formation in osteogenesis imperfecta: CT and MRI findings.

1998

Hyperplastic callus formation is a noteworthy condition in patients with osteogenesis imperfecta because it often mimicks osteosarcoma on radiography. The findings of CT and MRI in hyperplastic callus formation have not been reported. In the presented case, MRI demonstrated contrast enhancement and edema of the surrounding soft tisssue, consistent with benign as well as malignant disease. Computed tomography showed a calcified rim of the lesion which may be a useful feature to rule out osteosarcoma in this condition.

Deficiency of Nrf2 accelerates the effector phase of arthritis and aggravates joint disease

2011

14 páginas, 8 figuras, 1 tabla.-- et al.