Search results for "CAP"

showing 10 items of 8832 documents

Reduced serum protease activity in Complex Regional Pain Syndrome: The impact of angiotensin-converting enzyme and carboxypeptidases.

2021

Complex Regional Pain Syndrome (CRPS) occurs in about 2% of patients after fracture of the limbs. In an earlier clinical study with 102 probands we have shown that the serum protease network in CRPS might be less effective. Based on these results we hypothesized that angiotensin-converting enzyme (ACE) and carboxypeptidase N (CPN) activity contribute to the differences of labeled bradykinin (DBK) degradation by patients' sera. Details of the enzymatic processes remained however unclear. The contributions of ACE and CPN in the serum degradation of DBK were studied using specific inhibitors. CPN1-ELISA was performed in serum. It was confirmed that the majority of DBK was degraded by ACE and C…

medicine.medical_specialtyAngiotensinsmedicine.medical_treatmentClinical BiochemistryPharmaceutical ScienceBradykininCarboxypeptidasesBradykininAnalytical Chemistrychemistry.chemical_compoundInternal medicineDrug DiscoverymedicineHumansSpectroscopyProteasebiologyCaptoprilAngiotensin-converting enzymemedicine.diseaseBlood proteinsCarboxypeptidasePathophysiologyEndocrinologyComplex regional pain syndromechemistrybiology.proteinFemaleComplex Regional Pain Syndromesmedicine.drugPeptide HydrolasesJournal of pharmaceutical and biomedical analysis
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Concept and Treatment of Hydrocephalus in the Greco-Roman and Early Arabic Medicine

2007

In the ancient medical literature hydrocephalus was not often described although its existence and symptomatology were well known. Most detailed descriptions of hydrocephalus including the surgical treatment are extant in the encyclopaedic works on medicine of the physicians Oreibasios and Aetios from Amida from the 4th and 6th centuries AD, respectively. Because of their broad scientific interests, this type of physicians, typical for the late Roman empire, were known as philosophy-physicians (iota alpha tau rho o sigma o phi iota sigma tau alpha iota). They defined hydrocephalus in contrast to our present understanding as a fluid collection excluding abscesses visible as a bulging tumour …

medicine.medical_specialtyArabicNeurosurgeryAutopsyGreek WorldVentricular systemRoman WorldNeurosurgical ProceduresHumansMedicineTextbooks as TopicHistory AncientHistory 15th CenturyIntracranial pressureCaput succedaneumbusiness.industryArab WorldInfant NewbornMeningesInfantGeneral Medicinemedicine.diseaseHistory MedievalIntracranial Hemorrhage Traumaticlanguage.human_languageHydrocephalusSurgerySkullmedicine.anatomical_structureNeurologylanguageSurgeryNeurology (clinical)businessHydrocephalusmin - Minimally Invasive Neurosurgery
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Patógenos atípicos en pacientes hospitalizados con neumonía adquirida en la comunidad: una perspectiva mundial

2018

Abstract Background Empirical antibiotic coverage for atypical pathogens in community-acquired pneumonia (CAP) has long been debated, mainly because of a lack of epidemiological data. We aimed to assess both testing for atypical pathogens and their prevalence in hospitalized patients with CAP worldwide, especially in relation with disease severity. Methods A secondary analysis of the GLIMP database, an international, multicentre, point-prevalence study of adult patients admitted for CAP in 222 hospitals across 6 continents in 2015, was performed. The study evaluated frequency of testing for atypical pathogens, including L. pneumophila, M. pneumoniae, C. pneumoniae, and their prevalence. Ris…

medicine.medical_specialtyAtypical pathogensEpidemiologyPopulationSettore MED/10 - Malattie Dell'Apparato Respiratoriolcsh:Infectious and parasitic diseases03 medical and health sciences0302 clinical medicineMedical microbiologyCommunity-acquired pneumoniaInternal medicineEpidemiologyRisk Factors.Medicinelcsh:RC109-216030212 general & internal medicineeducationAged 80 and overeducation.field_of_studybusiness.industryIncidence (epidemiology)Atypical pathogenHealthcare-Associated PneumoniaChlamydophila pneumoniaemedicine.diseaseAntibiotic coverageCAPPneumoniaInfectious Diseases030228 respiratory systemLegionnaires' diseasebusinessResearch Article
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Aerobic capacity and respiratory patterns are better in recreational basketball-engaged university students than age-matched untrained males

2021

Abstract Study aim: To asses and compare the aerobic capacity and respiratory parameters in recreational basketball-engaged university students with age-matched untrained young adults. Material and methods: A total of 30 subjects were selected to took part in the study based on recreational-basketball activity level and were assigned to a basketball (BG: n = 15, age 22.86 ± 1.35 yrs., body height 185.07 ± 5.95 cm, body weight 81.21 ± 6.15 kg) and untrained group (UG: n = 15, age 22.60 ± 1.50 yrs., body height 181.53 ± 6.11 cm, body weight 76.89 ± 7.30 kg). Inspiratory vital capacity (IVC), forced expiration volume (FEV1), FEV1/IVC ratio, maximal oxygen consumption (VO2max), ventilatory thre…

medicine.medical_specialtyBasketballPhysiologybusiness.industryPhysical Therapy Sports Therapy and Rehabilitation030229 sport sciences030204 cardiovascular system & hematologyTeam-sport03 medical and health sciences0302 clinical medicineSpirometrySports medicineMaximal oxygen consumptionPhysical therapyQP1-981MedicineOrthopedics and Sports MedicineRespiratory systemRecreational basketballbusinessRC1200-1245RecreationAerobic capacityBiomedical Human Kinetics
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A meta-review of literature reviews assessing the capacity of patients with severe mental disorders to make decisions about their healthcare

2020

Abstract Background Determining the mental capacity of psychiatric patients for making healthcare related decisions is crucial in clinical practice. This meta-review of review articles comprehensively examines the current evidence on the capacity of patients with a mental illness to make medical care decisions. Methods Systematic review of review articles following PRISMA recommendations. PubMed, Scopus, CINAHL and PsycInfo were electronically searched up to 31 January 2020. Free text searches and medical subject headings were combined to identify literature reviews and meta-analyses published in English, and summarising studies on the capacity of patients with serious mental illnesses to m…

medicine.medical_specialtyBipolar DisorderMeta-reviewlcsh:RC435-571Bipolar disorderDecision MakingPsychological interventionContext (language use)PsycINFOCINAHLlcsh:PsychiatryMentally Ill PersonsHealth caremedicineHumansMental CompetencyDecision making capacityBipolar disorderPsychiatryLiterature reviewbusiness.industryBipolar disorder Decision making capacity Literature review Mental disorder Meta-review SchizophreniaMental DisordersMental illnessmedicine.diseaseSelf CarePsychiatry and Mental healthMental disorderPsychotic DisordersSchizophreniaSchizophreniabusinessResearch Article
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Dose-finding study of oxaliplatin associated to capecitabinebased preoperative chemoradiotherapy in locally advanced rectal cancer

2018

// Gemma Bruera 1, 2 , Mario Di Staso 3 , Pierluigi Bonfili 3 , Antonio Galvano 4 , Rosa Manetta 5 , Gino Coletti 6 , Roberto Vicentini 7 , Stefano Guadagni 2, 8 , Corrado Ficorella 2, 9 , Ernesto Di Cesare 2, 3 , Antonio Russo 4 and Enrico Ricevuto 1, 2 1 Oncology Territorial Care, S. Salvatore Hospital, Oncology Network ASL1 Abruzzo, University of L'Aquila, L'Aquila, Italy 2 Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila, L’Aquila, Italy 3 Radiotherapy, S. Salvatore Hospital, Oncology Network ASL1 Abruzzo, University of L’Aquila, L’Aquila, Italy 4 Medical Oncology, Department of Surgical, Oncological and Stomatological Sciences, University of Palermo,…

medicine.medical_specialtyCapecitabine; Chemoradiotherapy; Dose-finding; Locally advanced rectal cancer; Oxaliplatin; OncologyColorectal cancerSettore MED/06 - Oncologia Medicamedicine.medical_treatmentRectumchemoradiotherapyCapecitabine03 medical and health sciences0302 clinical medicinelocally advanced rectal cancermedicineMucositisbusiness.industryGeneral surgerycapecitabineoxaliplatinmedicine.diseaseOxaliplatinRadiation therapyRegimenmedicine.anatomical_structureOncology030220 oncology & carcinogenesisdose-findingClinical Research Paperbusiness030217 neurology & neurosurgeryChemoradiotherapymedicine.drug
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Noninvasive diagnostic techniques of port wine stain.

2021

Port-wine stain (PWS) is a benign capillary malformation that most commonly occurs in the head and neck. It is present at birth and progresses over time. It is formed by progressive dilatation of post-capillary venules and is associated with hypertrophy and nodularity with increasing age, leading to cosmetic disfigurement and psychological aggravation. It is caused by genetic mosaicism in GNAQ and GNA11 genes. Histopathology is the gold standard for assessment of PWS but it is invasive and may cause scarring. Inadequate characterization of the lesions may predispose to inadequate treatment protocols as well as higher treatment dosages. Clinical evaluation of treatment efficacy is subjective…

medicine.medical_specialtyCapillary malformationVascular MalformationsPort-Wine StainDermatologyStain030207 dermatology & venereal diseases03 medical and health sciences0302 clinical medicineOptical coherence tomographyMedicineHumansHemangioma CapillaryMicroscopy Confocalmedicine.diagnostic_testbusiness.industryUltrasoundInfant NewbornPort-wine stainGold standard (test)Laser Doppler velocimetrymedicine.diseaseTristimulus colorimeterTreatment Outcome030220 oncology & carcinogenesisRadiologybusinessJournal of cosmetic dermatologyREFERENCES
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Die CO 2 -Messung im Atemgas

1997

UNLABELLED Currently, even in prehospital emergency medicine (PEM), continuous end-tidal CO2 monitoring is frequently used as a sensitive and non-invasive technique in ventilated patients. Due to its central role, the continuous measurement of exhaled CO2 provides immediate information about the status of three essential functions of the organism: ventilation, circulation, and metabolism. METHODS Recent literature, obtained by a computer-guided search (Winspirs), and product information of all currently available capnometry devices were reviewed in detail. Firstly, the theoretical background of different CO2-measurement methods and techniques is described. Secondly, indications and specific…

medicine.medical_specialtyCapnographyContinuous measurementAnesthetic gasesmedicine.diagnostic_testbusiness.industrySystem of measurementUsabilityGeneral Medicinelaw.inventionCo2 monitoringAnesthesiology and Pain MedicinelawEmergency medicineVentilation (architecture)MedicinebusinessEnd tidal co2Der Anaesthesist
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Complications Through the Use of Viscoelastics

2000

Viscoelastic material retained behind the IOL may cause a capsular bag distension in the early postoperative period. These eyes accumulate a transparent substance in the closed chamber inside the capsular bag from the IOL blocking the capsular opening. The capsular bag distension was first discribed by Davison in 1990. Miyake et al. proposed a new classification of capsular block syndrome and supposed viscoelastic material to cause early-postoperative capsular block syndrome (Miyake et al., 1999). Capsular bag distension after optic capture of a sulcus-fixated IOL was described by Basti et al. (1999).

medicine.medical_specialtyCapsular block syndromegenetic structuresbusiness.industryOphthalmologyCapsular bagmedicinesense organsDistensionClosed chamberbusinesseye diseases
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Oxycodone extended release capsules for the treatment of chronic pain

2017

As a consequence of greater prescription opioid utilization, there has been the parallel increase in misuse, abuse, and overdose, which are serious risks. Associated new formulations may be safer. Areas covered: The introduction of abuse-deterrent opioid formulations and continuous programs to improve opioid prescribing practices may limit the opioid abuse and its consequences. Oxycodone extended release capsules are an extended-release (ER), microsphere-in-capsule abuse-deterrent-formulation designed to retain its extended-release properties following tampering or misuse (e.g., chewing, crushing). Studies have reported that this preparation is efficacious in patients with low back pain, le…

medicine.medical_specialtyCapsules03 medical and health sciences0302 clinical medicine030202 anesthesiologymedicineHumansPharmacology (medical)In patientChildIntensive care medicinebusiness.industryGeneral NeuroscienceChronic painHave Difficulty Swallowingmedicine.diseaseLow back painAnalgesics OpioidOpioidPrescription opioidDelayed-Action PreparationsAnesthesiaNeurology (clinical)Chronic Painmedicine.symptomExtended releasebusinessOxycodoneOxycodone030217 neurology & neurosurgerymedicine.drugExpert Review of Neurotherapeutics
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