Search results for "CAPE"

showing 10 items of 1938 documents

Cytotoxicity of tumor antigen specific human T cells is unimpaired by arginine depletion.

2013

Tumor-growth is often associated with the expansion of myeloid derived suppressor cells that lead to local or systemic arginine depletion via the enzyme arginase. It is generally assumed that this arginine deficiency induces a global shut-down of T cell activation with ensuing tumor immune escape. While the impact of arginine depletion on polyclonal T cell proliferation and cytokine secretion is well documented, its influence on chemotaxis, cytotoxicity and antigen specific activation of human T cells has not been demonstrated so far. We show here that chemotaxis and early calcium signaling of human T cells are unimpaired in the absence of arginine. We then analyzed CD8(+) T cell activation…

Cytotoxicity Immunologiclcsh:MedicineCD8-Positive T-LymphocytesARGINASELymphocyte ActivationGranzymesInterleukin 21Cytotoxic T cellIL-2 receptorlcsh:ScienceCells CulturedMultidisciplinarybiologyT CellsChemotaxisVaccinationCOFILINCD28Natural killer T cellCANCERmedicine.anatomical_structureMedicineScience & Technology - Other TopicsImmunotherapyResearch ArticleTumor ImmunologyEXPRESSIONINFILTRATING LYMPHOCYTESCARCINOMAGeneral Science & TechnologyT cellImmune CellsImmunologyArginineImmune SuppressionDENDRITIC CELLSImmunomodulationInterferon-gammaMART-1 AntigenMULTIPLE-MYELOMAMD MultidisciplinarymedicineImmune ToleranceHumansCalcium SignalingAntigen-presenting cellBiologyCell ProliferationCD40Science & TechnologyMULTIDISCIPLINARY SCIENCESPerforinlcsh:RImmunityImmunoregulationIN-VITROImmunologic SubspecialtiesMolecular biologybiology.proteinMYELOID SUPPRESSOR-CELLSClinical ImmunologyTumor Escapelcsh:QT-Lymphocytes CytotoxicPLoS ONE
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Investigating a simplified method for noninvasive genetic sampling in East African mammals using silica dried scat swabs

2020

Abstract Swabbing scat has proved to be an effective noninvasive method to collect DNA from mammals in the field. Previously, this method has relied on preservative liquids or freezing to preserve the DNA collected on swabs. In this study, we determine the effectiveness of using silica to simply dry the swab in field as an alternative way to prevent DNA degredation. Four species were included in the study; reticulated giraffe, impala, fringe‐eared oryx, and lion. Swabs were taken at multiple time points for giraffe and impala scat samples, with the lion and oryx sampled opportunistically. Mitochondrial DNA was successfully amplified and sequenced from scat swabs from all species; however, e…

DNA preservation0106 biological sciencesVeterinary medicinescatoryx010603 evolutionary biology01 natural sciences03 medical and health scienceslcsh:QH540-549.5biology.animalMultiple timeSampling (medicine)Ecology Evolution Behavior and SystematicsOriginal Researchgiraffe030304 developmental biologyNature and Landscape Conservationlion0303 health sciencesEcologybiologyReticulated giraffeimpalabiology.organism_classificationDNA extractionOryxlcsh:EcologyEcology and Evolution
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Growth form matters – Crustose lichens on dead wood are sensitive to forest management

2022

Lichens have a vital role in forest ecosystems and they are a threatened group in boreal forests. However, the conservation ecology of the total lichen community has very rarely been studied. Here we studied lichen species and communities, including macrolichens (=foliose and fruticose growth forms) and rarely studied crustose li-chens, on decaying wood in boreal spruce-dominated forests in Finland. We also studied obligate lignicoles that grow only on dead wood and are mostly crustose in growth form. Species richness and community composition were examined on decaying logs and natural or cut stumps of Picea abies at different decay stages (2-5) in 14 stands, half of which were natural or s…

DYNAMICSLOBARIA-PULMONARIASTAND CONTINUITYConservationManagement Monitoring Policy and LawSUBSTRATERed listed lichensboreal forestsOLD-GROWTHEPIPHYTIC LICHENSlahopuutNature and Landscape ConservationlajiensuojelujäkälätmetsänkäsittelyconservationSPECIES-DIVERSITYpuut (kasvit)FUNGIForestrymetsätluonnon monimuotoisuusmetsiensuojelumetsäekosysteemitboreaalinen vyöhykeBoreal forestsWood -inhabiting species1181 Ecology evolutionary biologywood-inhabiting speciesred listed lichensmetsänhoitoCALICIOID LICHENSForest Ecology and Management
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Size dependent carrier thermal escape and transfer in bimodally distributed self assembled InAs/GaAs quantum dots

2012

We have investigated the temperature dependent recombination dynamics in two bimodally distributed InAs self assembled quantum dots samples. A rate equations model has been implemented to investigate the thermally activated carrier escape mechanism which changes from exciton-like to uncorrelated electron and hole pairs as the quantum dot size varies. For the smaller dots, we find a hot exciton thermal escape process. We evaluated the thermal transfer process between quantum dots by the quantum dot density and carrier escape properties of both samples. © 2012 American Institute of Physics.

DYNAMICSMaterials scienceAtmospheric escapeCondensed matter physicsExcitonGeneral Physics and AstronomyElectronRate equationThermal transferEPITAXYCondensed Matter::Mesoscopic Systems and Quantum Hall EffectGallium arsenidechemistry.chemical_compoundCondensed Matter::Materials SciencechemistrySTATESself assembled quantum dots rate equations model carrier escape propertiesQuantum dotQuantum dot laserLUMINESCENCEPHOTOLUMINESCENCE
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Praktiskā piensaimniecība

1928

Saturs: I. Pienalopu izvēle, izkopšana un apkopšana. Piens, krējums un tā pārstrādāšana sviestā. II. Sierniecība. III. Piensaimniecības mašīnas.

Dairy farmingDairying:FORESTRY AGRICULTURAL SCIENCES and LANDSCAPE PLANNING::Product science::Food science [Research Subject Categories]PiensaimniecībaPiena lopkopībaPiena rūpniecība
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Maza uzņēmuma IT infrastruktūras pilnveidošana

2017

Kvalifikācijas darba mērķis ir izpētīt maza uzņēmuma IT infrastruktūru, piedāvāt un ieviest risinājumus, kas uzlabotu tās pārskatāmību un pārvaldību. Šī mērķa sasniegšanai uzņēmumā tika ieviesti sekojoši risinājumi - VMware virtualizācijas platforma un Ubuntu Landscape centralizētās vadības sistēma, kā arī uzlabotas iespējas veikt rezerves kopiju veidošanu un uzņēmuma sistēmu pārraudzību. Darba rezultātā sasniegtais samazināja laika un darba apjomu, kas nepieciešams uzņēmuma IT infrastruktūras uzturēšanai.

DatorzinātneLinuxLandscapeVmware ESXi 6.5virtualizācijaUbuntu
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Crónica de una pandemia: confinamiento en Castelló de la Plana, España

2021

Este artículo presenta los resultados de una investigación comenzada a raíz de la declaración del estado de alarma en España (Real Decreto [RD] No. 463/2020, de 14 de marzo) después que la Organización Mundial de la Salud (OMS) declarase la enfermedad por coronavirus 2019 (COVID-19) como pandemia el día 11 de marzo de 2020. Este decreto limitaba la libre circulación de las personas, así como el derecho de reunión, tanto en lugares públicos como privados, además de imponer la obligatoriedad de mantener una distancia de seguridad entre los individuos y la limitación del aforo en aquellos establecimientos que permanecían abiertos, entre otras medidas. Todo ello supuso un cambioen las rutinas d…

DecreeCoronavirus disease 2019 (COVID-19)General Arts and HumanitiesPolitical sciencePandemicGeneral Social SciencesLimitingObligationUrban landscapeFree movementHumanitiesWorld healthSociedade e Cultura
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Equilibrium properties of the reaction H2⇌ 2H by classical molecular dynamics simulations

2013

We have developed a classical molecular dynamics model for the hydrogen dissociation reaction, containing two- and three-particle potentials derived by Kohen, Tully and Stillinger. Two fluid densities were investigated for a wide range of temperatures, and 11 fluid densities were considered for one temperature. We report the temperature range where the degree of reaction is significant, and also where a stable molecule dominates the population in the energy landscape. The three-particle potential, which is essential for the reaction model and seldom studied, together with the two-particle interaction lead to a large effective excluded volume diameter of the molecules in the molecular fluid.…

Degree of reactioneducation.field_of_studyHydrogenPopulationGeneral Physics and AstronomyEnergy landscapechemistry.chemical_elementThermodynamicsChemical reactionStandard enthalpy of formationMolecular dynamicschemistryPhysical and Theoretical ChemistryeducationAmbient pressurePhys. Chem. Chem. Phys.
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Architettura in alzato. Questioni di territorio, paesaggio, ambiente

2021

Negata alla tipologia l’architettura del Sud nel saggio riconosce una specifica identità e perfetta eccezionalità nell’essenza del luogo. Se la facciata istituisce un rapporto con l’estetica del paesaggio, i temi che essa sottende definiscono altre significative relazioni. L’ordinamento logico delle membrature, la chiarezza geometrica e il rigore dei rapporti rimandano ad una architettura che si misura, ed è misura stessa, del territorio e della sua morfologia. A sua volta, lo spessore della facciata esprime la relazione con l’ambiente e interpreta in maniera poetica i condizionamenti climatici, intervenendo sul controllo della luce, sui vuoti nei paramenti murari, sulla determinazione dell…

Denied to typology Southern architecture in the essay recognizes a specific identity and perfect exceptionality in the essence of the place. If the facade establishes a relationship with the aesthetics of the landscape the underlying themes define other significant relationships. The logical ordering of the members the geometric clarity and the rigor of the relationships refer to an architecture that is measured and is a measure itself of the territory and its morphology. In turn the thickness of the facade expresses the relationship with the environment and interprets the climatic conditions in a poetic way intervening on the control of light on the voids in the wall faces on the determination of the shadow. In this way facade-proportion-thickness with the corresponding terms of landscape-territory-environment relationship define a double triad attributable to patterns and features typical of southern Italy and which however also belong to other southern Europe.Settore ICAR/14 - Composizione Architettonica E Urbana
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2020

Arts-based practices can support sustainability, combined with research that points out needs for intervention. We practiced environmental sensitivity and dialogic art with fifth-grade school pupil...

DialogicEcologybusiness.industryFace (sociological concept)Management Monitoring Policy and LawPublic relationsIntervention (law)Environmental educationAutomotive EngineeringSustainabilityAgency (sociology)Agricultural biodiversitySociologybusinessEcology Evolution Behavior and SystematicsNature and Landscape ConservationEcosystems and People
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