Search results for "CARDIAC-FUNCTION"

showing 2 items of 2 documents

New modes in non-invasive ventilation

2016

IF 2.536; International audience; Non-invasive ventilation is useful to treat some forms of respiratory failure. Hence, the number of patients receiving this treatment is steadily increasing. Considerable conceptual and technical progress has been made in recent years by manufacturers concerning this technique. This includes new features committed to improve its effectiveness as well as patient-ventilator interactions. The goal of this review is to deal with latest advances in ventilatory modes and features available for non-invasive ventilation. We present a comprehensive analysis of new modes of ventilator assistance committed to treat respiratory failure (hybrid modes) and central and co…

Pulmonary and Respiratory MedicineComplex sleep apneamedicine.medical_specialtyCentral sleep apneaAdaptive servo ventilation[ SDV.MHEP.PED ] Life Sciences [q-bio]/Human health and pathology/PediatricsCheyne-stokes respirationReview030204 cardiovascular system & hematologyPositive airway pressureRespiratory failure[SDV.MHEP.PSR]Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tractAssured pressure support03 medical and health sciences0302 clinical medicinemedicineNeurally adjusted ventilatory assistVentilatory modesHumansIntensive care medicineObstructive pulmonary-diseaseComplex sleep-apnea[SDV.MHEP.PED]Life Sciences [q-bio]/Human health and pathology/PediatricsNoninvasive Ventilationbusiness.industryDiaphragm electrical-activityNon invasive ventilationmedicine.diseaseNeuro adjusted ventilatory assistClinical PracticeRandomized controlled-trialAdaptative servo ventilationChronic heart-failure030228 respiratory systemRespiratory failurePediatrics Perinatology and Child HealthBreathingCentral sleep apneabusinessRespiratory InsufficiencyImproves cardiac-function[ SDV.MHEP.PSR ] Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tract
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VEGF-B-induced vascular growth leads to metabolic reprogramming and ischemia resistance in the heart

2014

Abstract Angiogenic growth factors have recently been linked to tissue metabolism. We have used genetic gain‐ and loss‐of function models to elucidate the effects and mechanisms of action of vascular endothelial growth factor‐B (VEGF‐B) in the heart. A cardiomyocyte‐specific VEGF‐B transgene induced an expanded coronary arterial tree and reprogramming of cardiomyocyte metabolism. This was associated with protection against myocardial infarction and preservation of mitochondrial complex I function upon ischemia‐reperfusion. VEGF‐B increased VEGF signals via VEGF receptor‐2 to activate Erk1/2, which resulted in vascular growth. Akt and mTORC1 pathways were upregulated and AMPK downregulated, …

VEGF‐Bmedicine.medical_specialtyMedicine (General)AngiogenesiseducationMOUSE HEARTIschemiaVEGF-B610 Medicine & healthmTORC1ischemiaBiologyQH426-470CONTRIBUTESchemistry.chemical_compoundangiogenesisR5-920CARDIAC-FUNCTIONInternal medicinemedicineGeneticsFAILUREta318Myocardial infarctionFATTY-ACID UPTAKEREPERFUSION INJURY610 Medicine & healthProtein kinase BMYOCARDIAL HYPERTROPHYAMPKta3121medicine.diseaseCell biologyARTERIOGENESISVascular endothelial growth factorMICEEndocrinologychemistry3121 General medicine internal medicine and other clinical medicineendothelial cellMolecular Medicine3111 BiomedicineReperfusion injurymetabolism
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