Search results for "CASS"
showing 10 items of 433 documents
Progress in the initial design activities for the European DEMO divertor: Subproject "Cassette"
2017
Abstract Since 2014 preconceptual design activities for European DEMO divertor have been conducted as an integrated, interdisciplinary R&D effort in the framework of EUROfusion Consortium. Consisting of two subproject areas, ‘Cassette’ and ‘Target’, this divertor project has the objective to deliver a holistic preconceptual design concept together with the key technological solutions to materialize the design. In this paper, a brief overview on the recent results from the subproject ‘Cassette’ is presented. In this subproject, the overall cassette system is engineered based on the load analysis and specification. The preliminary studies covered multi-physical analyses of neutronic, thermal,…
Biological effects and photodegradation by TiO(2) of terpenes present in industrial wastewater.
2010
Abstract The aim of this work was to study the biological effects of four monoterpenes, i.e. α-pinene, β-pinene, 3-carene and d -limonene present in the wastewater of a citrus transformation factory. The study was carried out by exposing V79 Chinese hamster cells to single terpene or to the mixture of four terpenes at concentrations corresponding to those in the wastewater evaluated by head space solid phase micro extraction and gas chromatography (HS-SPME-GC) analyses. Treatments with single or combined terpenes similarly affected cell vitality, but only the combined treatments induced the 6-thioguanine resistant mutants. Moreover the photocatalytic degradation of the four terpenes was suc…
Expression of Active Streptolysin O in Escherichia coli as a Maltose-Binding-Protein-Streptolysin-O Fusion Protein. The N-Terminal 70 Amino Acids are…
1996
Streptolysin 0 (SLO) is the prototype of a family of cytolysins that consists of proteins which bind to cholesterol and form very large transmembrane pores. Structure/function studies on the pore-forming cytolysin SLO have been complicated by the proteolytic inactivation of a substantial portion of recombinant SLO (rSLO) expressed in Escherichia coli. To overcome this problem, translational fusions between the E. coli maltose-binding protein (MBP) gene and SLO were constructed, using the vectors pMAL-p2 and pMAL-c2. MBP-SLO fusion proteins were degraded if secreted into the E. coli periplasm, but intact, soluble MBP-SLO fusion proteins were produced at high levels in the cytoplasm. Active S…
Caffeate and piperidine-3-ol derivatives from the stem bark of Cassia sieberiana
2019
A new caffeate derivative from the ethanol extract of the stem bark of Cassia sieberiana DC. is described herein along with the known secondary metabolites spectaline (2), iso-6-cassine (3), 3-O-methyl-chiro-inositol (4), monobehenin (5), octyl nonadecyloate (6), β-sitosterol (7), stigmasterol (8) and sitosterol 3-O-β-D-glucopyranoside (9). The chemical structures were elucidated by means of various spectroscopic and spectrometric techniques. Extract and isolated compounds were devoid of inhibitory action against the herein selected bacterial strains (MICs > 256 μg/mL) but showed capacities to reduce 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical (EC50 < 3 μg/mL) considerably better than the …
Symmetry meets AI
2021
We explore whether Neural Networks (NNs) can {\it discover} the presence of symmetries as they learn to perform a task. For this, we train hundreds of NNs on a {\it decoy task} based on well-controlled Physics templates, where no information on symmetry is provided. We use the output from the last hidden layer of all these NNs, projected to fewer dimensions, as the input for a symmetry classification task, and show that information on symmetry had indeed been identified by the original NN without guidance. As an interdisciplinary application of this procedure, we identify the presence and level of symmetry in artistic paintings from different styles such as those of Picasso, Pollock and Van…
Carbon Monoxide in the Cold Debris of Supernova 1987A
2013
We report spectroscopic and imaging observations of rotational transitions of cold CO and SiO in the ejecta of SN1987A, the first such emission detected in a supernova remnant. In addition to line luminosities for the CO J=1-0, 2-1, 6-5, and 7-6 transitions, we present upper limits for all other transitions up to J=13-12, collectively measured from the Atacama Large Millimeter Array (ALMA), the Atacama Pathfinder EXperiment (APEX), and the Herschel Spectral and Photometric Imaging REceiver (SPIRE). Simple models show the lines are emitted from at least 0.01 solar masses of CO at a temperature > 14 K, confined within at most 35% of a spherical volume expanding at ~ 2000 km/s. Moreover, we…
Polymorphisms in ABC transporter genes and concentrations of mercury in newborns - Evidence from two Mediterranean birth cohorts
2014
Background: The genetic background may influence methylmercury (MeHg) metabolism and neurotoxicity. ATP binding cassette (ABC) transporters actively transport various xenobiotics across biological membranes. Objective: To investigate the role of ABC polymorphisms as modifiers of prenatal exposure to MeHg. Methods: The study population consisted of participants (n = 1651) in two birth cohorts, one in Italy and Greece (PHIME) and the other in Spain (INMA). Women were recruited during pregnancy in Italy and Spain, and during the perinatal period in Greece. Total mercury concentrations were measured in cord blood samples by atomic absorption spectrometry. Maternal fish intake during pregnancy w…
Analysis of steady state thermal-hydraulic behaviour of the DEMO Divertor cassette body cooling circuit
2017
Abstract Within the framework of the Work Package DIV 1 – “Divertor Cassette Design and Integration” of the EUROfusion action, a research campaign has been jointly carried out by ENEA and University of Palermo to investigate the thermal-hydraulic performances of the DEMO divertor cassette cooling system. A comparative evaluation study has been performed considering the two different options under consideration for the divertor cassette body coolant, namely subcooled pressurized water and helium. The research activity has been carried out following a theoretical-computational approach based on the finite volume method and adopting a qualified Computational Fluid-Dynamic (CFD) code. CFD analy…
Flavonoids in sbtribe Centaureinae (Cass.) Dumort (tribe Carduae, Asteraceae): distibution and 13C spectral data
2012
Asteraceae Bercht. & J. Presl is one of the biggest and most economically important plant families. The taxonomy and phylogeny of Asteraceae is rather complex and according to the latest and most reliable taxonomic classification of Panero & Funk, based on the analysis of nine chloroplast regions, the family is divided into 12 subfamilies and 35 tribes. One of the largest tribes of Asteraceae is Cardueae Cass. with four subtribes (Carlininae, Echinopinae, Carduinae and Centaureinae) and more than 2500 species. Susanna & Garcia-Jacas have organized the genera of Centaureinae (about 800 species) into seven informal groups, which recent molecular studies have confirmed: 1. Basal genera; 2. Vol…
Bidirectional membrane transport: Simulations of transport inhibition in uptake studies explain data obtained with flavonoids
2006
The purpose of the simulations was to obtain an estimate of concentration-dependent uptake curves when two counteracting transporters are present. On the basis of this experimental data obtained with a pair of ovarian carcinoma cell lines, one of which was not expressing the exsorptive transporter P-glycoprotein and one of which was an MDR1-transfected, P-glycoprotein expressing variant, the kinetics of cellular uptake of the radiolabel (3)H-talinolol were calculated and the inhibitory constants at P-gp were determined for different flavonoids. With respect to the inhibition of P-gp function, among others, naringenin and isoquercitrin were identified as inhibitors, yet estimation of the inh…