Search results for "CAVI"

showing 10 items of 827 documents

Indicaxanthin from cactus pear fruit exerts anti-inflammatory effects in carrageenin-induced rat pleurisy.

2014

Nutritional research has shifted recently from alleviating nutrient deficiencies to chronic disease prevention. We investigated the activity of indicaxanthin, a bioavailable phytochemical of the betalain class from the edible fruit of Opuntia ficus-indica (L. Miller) in a rat model of acute inflammation. Rat pleurisy was achieved by injection of 0.2 mL of l-carrageenin in the pleural cavity, and rats were killed 4, 24, and 48 h later; exudates were collected to analyze inflammatory parameters, such as nitric oxide (NO), prostaglandin E2 (PGE2), interleukin-1b (IL-1b), and tumor necrosis factor-a (TNF-a); cells recruited in pleura were analyzed for cyclooxygenase-2 (COX-2), inducible nitric …

MalePyridinesmedicine.medical_treatmentPyridineAnti-Inflammatory AgentsMedicine (miscellaneous)PharmacologyCarrageenanchemistry.chemical_compoundLeukocytesInflammation MediatorPleural CavityNutrition and DieteticsbiologyOpuntiaBetaxanthinsNitric oxide synthaseAnti-Inflammatory AgentTumor necrosis factor alphamedicine.symptomInflammation MediatorsIndicaxanthinProstaglandin Emedicine.drug_classInflammationAnti-inflammatoryNitric oxidePlant ExtractmedicineAnimalsRNA MessengerRats WistarPleurisyInflammationIndicaxanthin phytochemicals inflammation pleurisy redox state.business.industryAnimalPlant ExtractsLeukocyteCarrageenanRatsDisease Models AnimalchemistryBetaxanthinFruitImmunologybiology.proteinRatbusinessPhytotherapyThe Journal of nutrition
researchProduct

Total antioxidant capacity of saliva and dental caries.

2013

Objective: Dental caries is one of the most common infectious diseases worldwide. Saliva has many functions in the oral cavity and is the first line defense against dental caries. Oxidative stress can affect initiation and progression of many inflammatory and infectious diseases such as dental caries. Thus the aim of this study was to evaluate the relationship between total antioxidant capacity (TAC) of saliva and dental caries. Study D esign: 100 healthy high school students (50 female and 50 male) with age range of 15 -17 years were randomly selected, divided to four groups. Unstimulated whole saliva specimens were collected at the morning. TAC of saliva was evaluated by spectrophotometri…

MaleSalivaAdolescentFirst lineDentistryFemale groupOdontologíaDental CariesOral cavityAntioxidantsstomatognathic systemCaries activeMedicineHumansStatistical analysisWhole salivaSalivaGeneral DentistryOral Medicine and Pathologybusiness.industry:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saludAntioxidant capacitystomatognathic diseasesOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASSurgeryResearch-ArticleFemalebusiness
researchProduct

Oral and oropharyngeal squamous cell carcinoma in young adults: A retrospective study in Granada University Hospital

2017

Background This study aims to evaluate and analyze the clinical features and outcomes of oral and oropharyngeal squamous cell carcinoma (SCC) in patients 45 years were randomly selected from the same database. A retrospective analysis was conducted to determine specific features including sites of occurrence, risk factors, sex distribution, socio-economic status, T stage at diagnosis, nodal involvement, degree of tumor differentiation, locoregional failure and overall survival at 5 years was. Further, the results of both groups were compared. Results The male-female ratio was 1.2:1 in the group of young adults and 2.03:1 in the group of patients with an age of >45 years. No significant diff…

MaleSurvivalDiseaseHospitals UniversityCavity cancers0302 clinical medicineRisk Factorsrisk factorsIncidence trendsMedicineYoung adultTongue cancerMiddle AgedUniversity hospital:CIENCIAS MÉDICAS [UNESCO]Risk-factorsOropharyngeal NeoplasmsHead and Neck Neoplasms030220 oncology & carcinogenesisUNESCO::CIENCIAS MÉDICASCarcinoma Squamous CellFemaleMouth Neoplasmsyoung adultsAdultmedicine.medical_specialtyMEDLINE03 medical and health sciencesAgeInternal medicineCarcinomaHumansMortalityGeneral DentistrySurvival rateOral and oropharyngeal squamous cell carcinomaRetrospective StudiesOral Medicine and PathologyNeck-cancer incidencebusiness.industrySquamous Cell Carcinoma of Head and NeckResearchPeopleRetrospective cohort study030206 dentistrypoor prognosismedicine.diseaseSurgeryOtorhinolaryngologySpainT-stageSurgerybusinessHeadMedicina Oral, Patología Oral y Cirugía Bucal
researchProduct

Evaluation of the xerostomia, taste and smell impairments after Covid-19

2021

Background The purpose of this study was to explore the effects of coronavirus disease 19 (Covid-19) on the oral cavity by evaluating the oral findings in the patients who recovered after treatment. Material and Methods This study involved confirmed Covid-19 patients whose treatment completed at least two weeks ago. A questionnaire consist of eight parts was applied to explore the oral findings after Covid-19. Also stimulated salivary flow rate was evaluated with a salivary flow test. Results 177 patients reached and 107 of them participate in the study. Regarding gender significant differences were found in terms of the presence of taste impairment after treatment (p=0.007), the degree of …

MaleTastemedicine.medical_specialty2019-20 coronavirus outbreakguided surgeryCoronavirus disease 2019 (COVID-19)dynamic guided surgeryOral cavityXerostomiaTaste Disordersdynamic navigationInternal medicineHumansMedicineIn patientTreatment completedGeneral DentistryUNESCO:CIENCIAS MÉDICASOral Medicine and PathologySARS-CoV-2business.industryResearchCOVID-19Salivary flow rateSmellOtorhinolaryngologycomputer assisted surgeryTasteFemaleSurgerybusinessAfter treatment
researchProduct

Effectiveness and safety of switching to entecavir hepatitis B patients developing kidney dysfunction during tenofovir

2019

Background and Aims: Tenofovir disoproxil fumarate (TDF) is recommended for chronic hepatitis B (CHB) treatment, but it may induce kidney dysfunction whose management is not yet known. This Italian, multicentre, retrospective study aimed to assess the efficacy and safety of switching to entecavir (ETV) patients who developed TDF-associated glomerular and/or tubular dysfunction. Methods: A total of 103 TDF-treated patients were included as follows: age 64 years, 83% male, 49% cirrhotics, 98% with undetectable HBV DNA, 47% with previous lamivudine resistance (LMV-R) and 71% previously treated with adefovir. Twenty-nine (28%) were switched to ETV because estimated glomerular filtration rate (e…

MaleTime FactorsSustained Virologic Responsehepatitis B viruKidneyGastroenterologyhepatitis B virus; liver; liver function tests; renal dysfunction; viral hepatitischemistry.chemical_compound0302 clinical medicine80 and overAdefovirChronicAged 80 and overKidneymedicine.diagnostic_testDrug Substitutionhepatitis B virus; liver; liver function tests; renal dysfunction; viral hepatitis; HepatologyEntecavirMiddle AgedHepatitis BHepatitis BTreatment Outcomemedicine.anatomical_structureItaly030220 oncology & carcinogenesisFemaleKidney Diseases030211 gastroenterology & hepatologyViral hepatitismedicine.drugAdultmedicine.medical_specialtyGuaninehepatitis B virus; liver; liver function tests; renal dysfunction; viral hepatitis; Adult; Aged; Aged 80 and over; Antiviral Agents; Female; Guanine; Hepatitis B Chronic; Humans; Italy; Kidney; Kidney Diseases; Male; Middle Aged; Recovery of Function; Retrospective Studies; Sustained Virologic Response; Tenofovir; Time Factors; Treatment Outcome; Drug Substitutionviral hepatitisRenal functionliverAntiviral Agents03 medical and health sciencesHepatitis B ChronicInternal medicinerenal dysfunctionmedicineHumansliver function testTenofovirAgedRetrospective StudiesCreatinineHepatologybusiness.industryviral hepatitiRecovery of Functionmedicine.diseasechemistryliver function testsbusinessLiver function testshepatitis B virus
researchProduct

Gastrointestinal helminths of cuvier’s beaked whales, ziphius cavirostris, From the Western Mediterranean

2004

We examined the gastrointestinal helminth fauna of 2 Cuvier's beaked whales, Ziphius cavirostris, stranded on the Spanish Mediterranean coast. Information regarding intestinal parasites of this species is provided for the first time. Six helminth taxa were identified. Thirty type II larvae of the nematode Anisakis sp. were found in the stomach and the intestine of both hosts; 2 type I larvae of Anisakis sp. were found in the intestine of 1 host. One juvenile of the acanthocephalan Bolbosoma vasculosum was found in the intestine; the metacestode Scolex pleuronectis was found mainly in the terminal colon and the anal crypts of both hosts; adult cestodes of Tetrabothrius sp., which may represe…

MaleWestern MediterraneanFaunaCestodaBiologyGastrointestinal helminths:CIENCIAS DE LA VIDA [UNESCO]Acanthocephalaparasitic diseasesMediterranean SeaUNESCO::CIENCIAS DE LA VIDAJuvenileHelminthsAnimalsIntestinal Diseases ParasiticEcology Evolution Behavior and SystematicsHost (biology)EcologyStomachZiphius cavirostrisWhales:CIENCIAS DE LA VIDA::Biología animal (Zoología) ::Parasitología animal [UNESCO]biology.organism_classificationZiphius cavirostrisAnisakisCuvier’s beaked whalesIntestinesMetacestodeUNESCO::CIENCIAS DE LA VIDA::Biología animal (Zoología) ::Parasitología animalNematodeSpainGastrointestinal helminths ; Cuvier’s beaked whales ; Ziphius cavirostris ; Western MediterraneanCestodaParasitologyFemaleHelminthiasis Animal
researchProduct

Effectiveness of dolutegravir-based regimens as either first-line or switch antiretroviral therapy: data from the Icona cohort

2019

Introduction: Concerns about dolutegravir (DTG) tolerability in the real-life setting have recently arisen. We aimed to estimate the risk of treatment discontinuation and virological failure of DTG-based regimens from a large cohort of HIV-infected individuals. Methods: We performed a multicentre, observational study including all antiretroviral therapy (ART)-naïve and virologically suppressed treatment-experienced (TE) patients from the Icona (Italian Cohort Naïve Antiretrovirals) cohort who started, for the first time, a DTG-based regimen from January 2015 to December 2017. We estimated the cumulative risk of DTG discontinuation regardless of the reason and for toxicity, and of virologica…

Maleadverse eventadverse events; antiretroviral therapy; cohort study; discontinuation; dolutegravir; toxicity; Adult; Anti-HIV Agents; Cohort Studies; Dideoxynucleosides; Female; HIV Infections; Heterocyclic Compounds 3-Ring; Humans; Italy; Male; Middle Aged; Prospective Studies; Retrospective Studies; Tenofovir; Treatment Outcomeadverse events; antiretroviral therapy; cohort study; discontinuation; dolutegravir; toxicity;HIV InfectionsPiperazinesCohort Studies0302 clinical medicineHeterocyclic CompoundsAbacavirRetrospective StudieMedicineHIV InfectionProspective Studies030212 general & internal medicineProspective cohort studyResearch Articlesadverse events; antiretroviral therapy; cohort study; discontinuation; dolutegravir; toxicityHazard ratioMiddle AgedDideoxynucleosidedolutegravirTreatment OutcomeInfectious DiseasesTolerabilityItalyCohortFemalePublic Health0305 other medical scienceHeterocyclic Compounds 3-RingResearch Articlemedicine.drugHumanAdultmedicine.medical_specialtyAnti-HIV AgentsPyridonesantiretroviral therapySettore MED/17 - MALATTIE INFETTIVE3-RingLower riskNO03 medical and health sciencesInternal medicineOxazinescohort studyHumansTenofovirRetrospective Studies030505 public healthbusiness.industryEnvironmental and Occupational HealthPublic Health Environmental and Occupational HealthAnti-HIV AgenttoxicityRetrospective cohort studyantiretroviral therapy; dolutegravir; cohort study; discontinuation; toxicity; adverse eventsDideoxynucleosidesadverse eventsDiscontinuationProspective Studieadverse events; antiretroviral therapy; cohort study; discontinuation; dolutegravir; toxicity; Public Health Environmental and Occupational Health; Infectious DiseasesCohort Studiebusinessdiscontinuation
researchProduct

Cholesteatoma of the hypotympanum in a patient with Treacher Collins syndrome

2014

In the present article we report a cholesteatoma of the hypotympanum extending to the jugular foramen in a 16-year-old male with Treacher Collins syndrome. Preoperative imaging excluded jugular paraganglioma and set the diagnosis of cholesteatoma. We discuss the operative treatment via a large hypotympanotomy and creation of an open hypotympanic cavity. To the authors' knowledge this is the first description of hypotympanal cholesteatoma with such an extension, being treated through this approach.

Malemedicine.medical_specialtyAdolescentHypotympanotomyOpen cavityEar MiddlemedicineHumansCholesteatoma Middle Earbusiness.industryCholesteatomaGeneral Medicinemedicine.diseaseJugular paragangliomaMagnetic Resonance ImagingSurgerymedicine.anatomical_structureOtorhinolaryngologyMiddle earSurgeryTomography X-Ray ComputedbusinessTreacher Collins syndromeMandibulofacial DysostosisJugular foramenPreoperative imagingAuris Nasus Larynx
researchProduct

Nasal tactile sensitivity in elderly

2010

Conclusion: Although older people varied widely in tactile sensitivity, our results show that tactile thresholds increased with age. Objectives: The aim of this study was to evaluate the effects of aging on nasal tactile sensitivity. Methods: A total of 160 healthy patients aged between 50 and 90 years were included. According to their age, patients were divided into groups (A, B, C, D, E, F, G, and H). From the age of 50, each group included subjects with an age range of 5 years (i.e. group A, 50-55 years; group B, 56-60 years, etc.). Each patient's outcome was assessed through the nasal monofilament test: a set of 20 Semmes-Weinstein monofilaments was used to detect nasal sensitivity for …

Malemedicine.medical_specialtyAgingMonofilament test; aging process; sensory lossTurbinates markerssensory lossMonofilament test aging process sensory lossReference Valuesaging processMedicineHumansNoseAgedAged 80 and overbusiness.industry eventSensory lossGeneral MedicineMiddle AgedMonofilament test; aging process; sensory loss; age-related decline; markers; nerve; event; nose; pain nerveSurgerySettore MED/31 - Otorinolaringoiatriamedicine.anatomical_structureOtorhinolaryngologyTouchage-related declineAnesthesiaReference valuesSensory ThresholdsFemale noseNasal CavityMonofilament test painbusinessOlder people
researchProduct

Ipsilateral facial weakness in upper medullary infarction-supranuclear or infranuclear origin?

1999

We describe two patients with upper medullary infarctions showing ipsilateral facial weakness and relative sparing of the upper facial muscles. Electrophysiological follow-up using transcranial magnetic stimulation of the motor cortex in combination with stimulation of the peripheral facial nerve disclosed a supranuclear (corticofacial) tract lesion in one patient and a partial nuclear/infranuclear intra-axial facial nerve lesion in another.

Malemedicine.medical_specialtyBrain Stem InfarctionsMedullary cavitymedicine.medical_treatmentFacial MusclesLesionReflexmedicineHumansAgedParesisMedulla OblongataMuscle Weaknessbusiness.industryMotor CortexFacial weaknessAnatomyMiddle AgedMagnetic Resonance ImagingFacial nerveElectric StimulationSurgeryTranscranial magnetic stimulationFacial Nervestomatognathic diseasesFacial musclesmedicine.anatomical_structureNeurologyNeurology (clinical)medicine.symptombusinessMotor cortexJournal of Neurology
researchProduct