Search results for "CBA"

showing 10 items of 130 documents

T-cell-derived helper factor allows Lyt 123 thymocytes to differentiate into cytotoxic T lymphocytes.

1979

IT is generally accepted that the diversity of T-cell responsiveness is generated in the thymus1. It is also known that except for a few Lyt 1 cells all thymocytes express the Lyt 123 phenotype2,3. Surprisingly, thymocytes are poorly responsive in vitro4, and only the medullary thymocytes, comprising 5–10% of the total thymic cell population, show an in vitro responsiveness comparable with that of peripheral T cells5. Cortical thymocytes, comprising 90–95% of all thymocytes, have previously been considered to be immature and immunologically incompetent4. The result reported here show that thymocytes are able to generate alloantigen-, virus- and hapten-specific cytotoxic T lymphocytes (CTL),…

Cytotoxicity Immunologiceducation.field_of_studyIsoantigensMultidisciplinaryT cellT-LymphocytesPopulationhemic and immune systemschemical and pharmacologic phenomenaBiologyMolecular biologyVirusIn vitroThymic epitheliumCTL*Micemedicine.anatomical_structureAntigens SurfaceCell separationmedicineMice Inbred CBACytotoxic T cellAnimalseducationNature
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Anti H-2Dd alloreactivity mediated by herpes-simplex-virus specific cytotoxic H-2k T lymphocytes is associated with H-2Dk.

1980

Herpes-simplex-virus (HSV) specific, H-2k-restricted, immune cytotoxic T lymphocytes also lyse noninfected H-2d target cells. Genetic mapping studies revealed that HSV-specific Dk-restricted CTL cross-react with allogeneic targets expressing Dd alloantigens. Cold target inhibition experiments indicate that only a minority of HSV-specific CTL mediate cross-reactive cytolysis. The data give an example of where the phenomenon of H-2-restricted versus nonrestricted responsiveness is not due to distinct subsets of T cells but solely depends on the antigenic determinants recognized.

Cytotoxicity ImmunologicvirusesImmunologychemical and pharmacologic phenomenaBiologyCross Reactionsmedicine.disease_causeEpitopeEpitopesMiceImmune systemAntigenIsoantibodiesGeneticsmedicineCytotoxic T cellAnimalsSimplexvirusCytotoxicityHistocompatibility Antigen H-2DMice Inbred BALB CH-2 AntigensVirologyCytolysisCTL*Herpes simplex virusImmunologyMice Inbred CBAT-Lymphocytes CytotoxicImmunogenetics
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DNA integrity, growth pattern, spindle formation, chromosomal constitution and imprinting patterns of mouse oocytes from vitrified pre-antral follicl…

2010

Cryopreservation of follicles for culture and oocyte growth and maturation in vitro provides an option to increase the number of fertilizable oocytes and restore fertility in cases where transplantation of ovarian tissue poses a risk for malignant cell contamination. Vitrification for cryopreservation is fast and avoids ice crystal formation. However, the influences of exposure to high concentrations of cryoprotectants on follicle development, oocyte growth and maturation, and particularly, on the DNA integrity and methylation imprinting has not been studied systematically. Follicle survival and development, DNA damage, oocyte growth patterns, maturation, spindle formation and chromosomal c…

DNA RepairSpindle ApparatusBiologyCryopreservationsnRNP Core ProteinsAndrologyGenomic ImprintingMiceOogenesisOvarian FolliclemedicineAnimalsaneuploidyOvarian follicleGeneticsCryopreservationRehabilitationObstetrics and GynecologyDNADNA MethylationAntral follicleOocyteVitrificationTransplantationMice Inbred C57BLmedicine.anatomical_structureDifferentially methylated regionsoocyte maturationReproductive MedicineDNA methylationMice Inbred CBAOocytesDNA damageCpG IslandsFemaleimprintingGenomic imprintingcryopreseration
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Identification of Critical Genes for Growth in Olive Brine by Transposon Mutagenesis of Lactobacillus pentosus C11

2013

ABSTRACT Olive brine represents a stressful environment due to the high NaCl concentration, presence of phenolic compounds known as antimicrobials, and low availability of nutrients. Thus, only a few strains of lactic acid bacteria (LAB) are adapted to grow in and ferment table olives. To identify the mechanisms by which these few strains are able to grow in olive brine, Lactobacillus pentosus C11, a particularly resistant strain isolated from naturally fermented table olives, was mutagenized by random transposition using the P junc -TpaseIS 1223 system (H. Licandro-Seraut, S. Brinster, M. van de Guchte, H. Scornec, E. Maguin, P. Sansonetti, J. F. Cavin, and P. Serror, Appl. Environ. Microb…

DNA Bacterial[SDV.SA]Life Sciences [q-bio]/Agricultural sciencesPROTEIN EXPRESSIONMutantGREEN OLIVESGenetics and Molecular BiologyLactobacillus pentosusSodium ChlorideBINDING PROTEINmedicine.disease_causeApplied Microbiology and BiotechnologyMicrobiology03 medical and health scienceschemistry.chemical_compoundBriningOleaLACTIC-ACBACTERIAmedicineSTRESS-RESPONSE[ SDV.SA ] Life Sciences [q-bio]/Agricultural sciencesEscherichia coliGene Library030304 developmental biology2. Zero hunger0303 health sciencesEcologybiologyReverse Transcriptase Polymerase Chain ReactionSTARTER CULTURE030306 microbiologyPHENOLIC-COMPOUNDSbiology.organism_classificationLactic acidLactobacilluschemistryMutagenesisTABLE OLIVESESCHERICHIA-COLIFermentationDNA Transposable ElementsFood MicrobiologySaltsFermentationTransposon mutagenesisPLANTARUM LPCO10Multiplex Polymerase Chain ReactionBacteriaFood ScienceBiotechnologyApplied and Environmental Microbiology
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Komercbanku resursu avotu analīze eirozonā

2016

Bakalaura darba tēma ir “Komercbanku resursu avotu analīze eirozonā”. Darba mērķis ir balstoties uz teorētiskām nostādnēm par komercbanku resursu avotu nozīmi banku stabilitātē, veikt eirozonas komercbanku resursu avotu un procenta likmju analīzi, izdarīt secinājumus un sniegt priekšlikumus resursu avotu struktūras sabalansēšanai bankas darbības stabilitātes uzlabošanas mērķiem. Darbs sastāv no 3 nodaļām un 6 apakšnodaļām. Pirmajā nodaļā apskatīti, banku resursu avoti un to saistība ar finanšu riskiem. Otrajā nodaļā analizēts, eirozonas komercbanku resursu avotu īpatsvars un procentu likmju izmaiņas. Trešajā nodaļā analizētas Latvijas komercbanku resursu avotu īpatsvara izmaiņas. Darba apjo…

Eirozonas komercbanku resursu avotiFinanšu riskiEkonomikaEirosistēmaResursiLatvijas komercbanku resursu avoti
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The oxidizing agent tertiary butyl hydroperoxide induces disturbances in spindle organization, c-meiosis, and aneuploidy in mouse oocytes

1996

It has been recently proposed that a concomitant generation of oxidative stress of oocytes with increasing maternal age may be a major factor responsible for the age-related increase in aneuploid conceptions. As a preliminary step in the testing of this hypothesis, we need to confirm that oxidative stress in itself can induce errors in chromosome segregation. In order to achieve this goal, germinal vesicle (GV)-stage mouse oocytes from unstimulated ICR and (C57BL x CBA) F1 hybrid female mice were matured in vitro for 9 h for metaphase I (MI) oocytes or 16 h for metaphase II (MII) oocytes in the presence of varying concentrations of the oxidizing agent tertiary-butyl hydroperoxide (tBH). MII…

EmbryologyAneuploidyIn Vitro TechniquesBiologyChromosome segregationMicetert-ButylhydroperoxideMeiosisBone plateGeneticsmedicineAnimalsHumansMolecular BiologyMice Inbred ICRMicroscopy ConfocalGerminal vesicleMeiosis IIObstetrics and GynecologyCell BiologyAneuploidyOxidantsmedicine.diseaseOocyteMolecular biologyPeroxidesCell biologyMice Inbred C57BLMeiosisOxidative Stressmedicine.anatomical_structureReproductive MedicineMice Inbred CBAOocytesSpindle organizationFemaleMaternal AgeDevelopmental Biology
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Finansiālās situācijas izpēte Swedbank AS

2021

Komercbanku finansiālā stāvokļa novērtēšanas tēma ietver sevī milzīgo zinātnisko un praktisko vērtību, kas saistīta ar banku stabilu darbības nodrošināšanu. Katram ir saprotams, ka no bankas izvēles ir atkarīga personāla labklājība un finanšu drošība gan fiziskām personām, gan juridiskām personām. Tādējādi tiek veikta finanšu analīze, lai pilnveidotu bankas darbību. Bakalaura darba mērķis ir, pielietojot finanšu analīzes teorētiskās atziņas, veikt AS ”Swedbank” finansiāla stāvokļa analīzi, un, pamatojoties uz pētījuma rezultātiem, izvirzīt secinājumus un izstrādāt priekšlikumus darbības pilnveidošanai. Bakalaura darba autore, veicot AS “Swedbank” finansiālās situācijas analīzi, secina ka ko…

Finanšu analīzeCommercial bankEkonomika un uzņēmējdarbībaFinancial analysisKomercbankaFinanšu rādītāji
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A/S Swedbank finanšu stāvokļa analīze

2018

Mūsdienu komercbankas sistēma atrodas nepārtrauktā mijiedarbībā ar ārējo vidi, it īpaši ar ekonomikas funkcionēšanu. Līdz ar to informācija par to stabilitāti, ko sniedz finanšu analīze, ir svarīga ne tikai potenciālajiem klientiem un pašām kredītiestādēm, bet arī uzraudzības iestādēm. Problēmu agrā diagnostika un komercbanku sistēmas stabilitātes nostiprināšana ļauj mazināt krīžu iespējamību un to sekas. Bakalaura darba mērķis ir veikt Swedbank finansiālā stāvokļa analīzi, izdarīt secinājumus un sniegt priekšlikumus. Bakalaura darba uzdevumi ir izpētīt bankas finanšu pārskatu analīzes metodes, savākt un apkopot informāciju par bankas vēsturi, izanalizēt bankas lomu Latvijas komercbanku sis…

Finanšu analīzeEkonomikaSwedbankKomercbankaFinanšu rādītāji
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Komercbankas “Swedbank” darbības finanšu analīze

2016

Mūsdienās komercbankas ir cieši saistītas ar sabiedrības ikdienas dzīvi, bet to darbības finanšu analīze sagādā ārējiem lietotājiem problēmas specializētas literatūras trūkuma dēļ. Tāpēc sabiedrība ne vienmēr spēj precīzi noteikt vai ir vērts sadarboties ar komercbanku. Šī diplomdarba mērķis ir veikt komercbankas „Swedbank” darbības finanšu analīzi, veikt secinājumus un noteikt priekšlikumus darbības uzlabošanai. Mērķa sasniegšanai autore raksturoja un analizēja bankas riskus, aktīvu un pašu kapitāla ienesīgumu, bankas darbības vērtējuma koeficientus. Lai gūtu pilnīgu priekšstatu par komercbankas “Swedbank” finanšu analīzes rezultātiem, iegūti koeficienti tiek salīdzināti ar tādiem pašiem k…

Finanšu koeficientiKomecbankaFinanšu analīzeEkonomikaDarbības analīze
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Long-term effects of delayed motherhood in mice on postnatal development and behavioural traits of offspring

2003

BACKGROUND: Some epidemiological evidence tentatively suggests that children born to older parents may have lower intellectual development and maturity than children whose parents are younger. This study aims to analyse the long-term effects of delayed motherhood in mice on postnatal development and behavioural traits later in life. METHODS: Hybrid females, either at the age of 10 weeks or 51 weeks, were individually housed with a randomly selected 12-14 week old hybrid male. After a postweaning resting period of 1 week, dams were caged again with a new randomly selected 12-14 week old male. This sequence of events was repeated until old females reached the end of their reproductive life. R…

GerontologyIntellectual developmentOffspringPhysiologyMorris water navigation taskReproductive BehaviorGrowthMotor ActivityBiologyDiscrimination LearningMicePregnancySensorimotor integrationAvoidance LearningAnimalsHumansAdvanced maternal ageYoung adultMaze LearningBehavior AnimalReproductionRehabilitationReproductive lifeObstetrics and GynecologyMice Inbred C57BLReproductive MedicineAgeingModels AnimalMice Inbred CBAFemaleMaternal AgeHuman Reproduction
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