Search results for "CEDU"

showing 10 items of 2453 documents

Hospital and outpatient models for Hematopoietic Stem Cell Transplantation: A systematic review of comparative studies for health outcomes, experienc…

2021

The number of Hematopoietic Stem Cell Transplantations has risen in the past 20 years. The practice of outpatient Hematopoietic Stem Cell Transplantation programs is increasing in an attempt to improve the quality of patient care and reduce the demand for hospital admission. A systematic review of 29 comparative studies between in-hospital and outpatient treatment of Hematopoietic Stem Cell Transplantation, with no restriction by outpatient regime was conducted. This study aims to analyse the current evidence on the effects of the outpatient model on patient-centred outcomes, comparing both in-hospital and outpatient models for autologous and allogeneic HSCT using the Triple Aim framework: …

Cell Transplantationmedicine.medical_treatmentFeversHematopoietic stem cell transplantationHealth careOutpatientsMedicine and Health SciencesBlood and Lymphatic System ProceduresOutpatient clinicMultidisciplinaryMortality rateQRHematopoietic Stem Cell TransplantationHematopoietic stem cellResearch AssessmentHospitalsSurvival Ratemedicine.anatomical_structureSystematic reviewModels EconomicCosts and Cost AnalysisMedicineResearch Articlemedicine.medical_specialtyPatientsSystematic ReviewsDeath RatesScienceSurgical and Invasive Medical ProceduresHealth outcomesResearch and Analysis MethodsTransplantation AutologousDisease-Free SurvivalQuality of life (healthcare)Signs and SymptomsPopulation MetricsmedicineHumansTransplantation HomologousIntensive care medicineOutpatient ClinicsTransplantationInpatientsPopulation Biologybusiness.industryBiology and Life SciencesLength of StayHealth CareHealth Care FacilitiesQuality of LifeClinical MedicinebusinessStem Cell TransplantationPloS one
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Design of enzyme-mediated controlled release systems based on silica mesoporous supports capped with ester-glycol groups

2012

[EN] An ethylene glycol-capped hybrid material for the controlled release of molecules in the presence of esterase enzyme has been prepared. The final organic-inorganic hybrid solid S1 was synthesized by a two-step procedure. In the first step, the pores of an inorganic MCM-41 support (in the form of nanoparticles) were loaded with [Ru(bipy) 3]Cl 2 complex, and then, in the second step, the pore outlets were functionalized with ester glycol moieties that acted as molecular caps. In the absence of an enzyme, release of the complex from aqueous suspensions of S1 at pH 8.0 is inhibited due to the steric hindrance imposed by the bulky ester glycol moieties. Upon addition of esterase enzyme, del…

Cell viabilityINGENIERIA DE LA CONSTRUCCIONEthyleneRuthenium complexesMCM-41 supportsCytotoxicityGlycol derivativesEsteraseFunctionalizedOrganic-inorganic hybrid solidsGlycolschemistry.chemical_compoundQUIMICA ORGANICATumor Cells CulturedElectrochemistryControlled release systemsOrganic chemistryControlled releaseGeneral Materials ScienceSteric hindrancesMCF-7 cellsSpectroscopyHydrolysisEsterasesSilicaEstersSurfaces and InterfacesSilicon DioxideCondensed Matter PhysicsControlled releaseChlorine compoundsEster bondsBody fluidsHybrid materialsHybrid materialPorosityCell deathCell SurvivalSurface PropertiesCytotoxic drugsRutheniumHydrolysisEnzymatic hydrolysisEsterase enzymesPolymer chemistryHumansCamptothecin (CPT)Molecular capSize reductionsTherapeutic ApplicationEthylene glycolTwo-step procedureEsterificationSuspensions (fluids)Ruthenium compoundsQUIMICA INORGANICAMesoporous supportOligo(ethylene glycol)Cell internalizationMolecular gatesConfocal microscopychemistryEnzymatic hydrolysisEnzyme-mediated hydrolysisNanoparticlesCamptothecinCell cultureMesoporous materialAqueous suspensionsEthylene glycolHeLa Cells
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Improved technique for stereotactic placement of nerve grafts between two locations inside the rat brain

2008

Peripheral nerve grafts have shown the ability to facilitate central axonal growth and regenerate the adult central nervous system. However, the detailed description of a technique for atraumatic graft placement within the brain is lacking. We present a stereotactic procedure to implant a peripheral nerve graft within a rat's brain with minimal brain tissue damage. The procedure permits a correct graft placement joining two chosen points, and the survival and integration of the graft in the host tissue with a light glial reaction, with evidence of central axonal growth inside the graft, at least up to 8 weeks after its implantation. (C) 2008 Elsevier B.V. All rights reserved.

Central nervous systemNigrostriatal pathwayPeripheral nerve graftHost tissueStereotaxic TechniquesMicroscopy Electron TransmissionPeripheral nervemedicineAnimalsRegenerationNigrostriatal pathwaybusiness.industryGeneral NeuroscienceRegeneration (biology)Peripheral nerve graftsBrainAnatomyRat brainSciatic NerveNerve RegenerationRatssurgical procedures operativemedicine.anatomical_structureGrafting stereotactic cannulaStereotactic placementImplantbusiness
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Effect of bioglass on growth and biomineralization of SaOS-2 cells in hydrogel after 3D cell bioprinting.

2014

We investigated the effect of bioglass (bioactive glass) on growth and mineralization of bone-related SaOS-2 cells, encapsulated into a printable and biodegradable alginate/gelatine hydrogel. The hydrogel was supplemented either with polyphosphate (polyP), administered as polyP • Ca2+-complex, or silica, or as biosilica that had been enzymatically prepared from ortho-silicate by silicatein. These hydrogels, together with SaOS-2 cells, were bioprinted to computer-designed scaffolds. The results revealed that bioglass (nano)particles, with a size of 55 nm and a molar ratio of SiO2 : CaO : P2O5 of 55 : 40 : 5, did not affect the growth of the encapsulated cells. If silica, biosilica, or polyP …

Ceramicsfood.ingredientAlginateslcsh:MedicineSurgical and Invasive Medical ProceduresBiocompatible MaterialsGelatinMineralization (biology)BiochemistryHydrogel Polyethylene Glycol Dimethacrylatelaw.inventionCell Linechemistry.chemical_compoundfoodCalcification PhysiologicTissue engineeringlawMedicine and Health SciencesHumansBiomechanicsParticle Sizelcsh:ScienceSaos-2 cellsCell ProliferationMultidisciplinaryBone DevelopmentTissue EngineeringTissue ScaffoldsChemistryPolyphosphatelcsh:RBioprintingBiology and Life SciencesChemical engineeringBioactive glassSelf-healing hydrogelsGelatinNanoparticleslcsh:QBiomineralizationResearch ArticlePLoS ONE
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Ectoparasites, nest site choice and breeding success in the pied flycatcher

1994

It has recently been suggested that nest box studies might bias the measurement of behavioural and life-history traits, because the removal of old nests may reduce the load of ectoparasites. This experimental artefact may have notable effects on nest site choice and breeding success in cavity-breeding birds. We tested (i) if pied flycatchers Ficedula hypoleuca prefer clean nest boxes and (ii) if old nest material affects the number of parasites and the breeding success of pied flycatchers. In the first experiment we offered birds one cleaned nest box and one nest box with old nest material from the previous year. The two nest boxes were placed in very similar sites near each other. In this …

CeratophyllidaeFleaNestbiologyEcologyEctoparasitismFicedulaNest sitebiology.organism_classificationCeratophyllus gallinaeNest boxEcology Evolution Behavior and SystematicsOecologia
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The role of transcranial magnetic stimulation in the study of cerebellar cognitive function.

2007

Transcranial magnetic stimulation (TMS) allows non-invasive stimulation of brain structures. This technique can be used either for stimulating the motor cortex, recording motor evoked potentials from peripheral muscles, or for modulating the excitability of other non-motor areas in order to establish their necessity for a given task. TMS of the cerebellum can give interesting insights on the cerebellar functions. Paired-TMS techniques, delivering stimuli over the cerebellum followed at various interstimulus intervals by stimuli over the motor cortex, allow studying the pattern of connectivity between the cerebellum and the contralateral motor cortex in physiological as well as in pathologic…

CerebellumElementary cognitive taskAnimals; Humans; Cerebellum; Transcranial Magnetic Stimulation; Cognitionmedicine.medical_treatmentCerebellum; Cognitive functions; TMS;Muscle memorybehavioral disciplines and activitiesProcedural memoryNOCognitionCerebellummedicineAnimalsHumanscerebellum; cognitive functions; tmsWorking memoryCognitionTranscranial Magnetic StimulationCognitive functionsTranscranial magnetic stimulationmedicine.anatomical_structurenervous systemNeurologyTMSSettore MED/26 - NeurologiaNeurology (clinical)PsychologyNeuroscienceMotor cortexCerebellum (London, England)
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Beyond sentinel node algorithm. Toward a more tailored surgery for cervical cancer patients

2016

none 12 Nowadays cervical cancer is frequently diagnosed at early stage. For these patients lymph node metastasis (LNM) is considered the most important prognostic factor. During the last decade many efforts have been made to reduce rate of complications associated with lymphadenectomy (LND). A great interest has arisen in sentinel lymph node (SLN) biopsy as a technique able to decrease number of LND performed and, at the same time, to assess lymph nodal status. High diagnostic performances have been reached thanks to SLN surgical algorithm. However, despite the efforts, about 25% of these patients undergo at least unilateral LND to meet NCCN recommendations. Data of women with Internationa…

Cervical cancer; early stage; lymphadenectomy; sentinel lymph node; Oncology; Radiology Nuclear Medicine and Imaging; Cancer ResearchCancer Researchmedicine.medical_treatmentUterine Cervical NeoplasmsCervical cancer; early stage; lymphadenectomy; sentinel lymph node0302 clinical medicinesentinel lymph nodeNuclear Medicine and ImagingMedicineStage (cooking)Original ResearchCervical cancer030219 obstetrics & reproductive medicinemedicine.diagnostic_testSentinel nodeMiddle Agedearly stagePrognosisOncology030220 oncology & carcinogenesisLymphatic MetastasisFemaleRadiologyAlgorithmAlgorithmsAdultmedicine.medical_specialtySentinel lymph nodeUnnecessary ProceduresHysterectomy03 medical and health sciencesBiopsyHumansRadiology Nuclear Medicine and imagingRadical HysterectomyAgedNeoplasm StagingRetrospective StudiesHysterectomybusiness.industrySentinel Lymph Node BiopsyClinical Cancer Researchmedicine.diseaseSurgerySettore MED/40 - GINECOLOGIA E OSTETRICIAlymphadenectomyCervical cancerLymph Node ExcisionLymphadenectomyNeoplasm Gradingbusiness
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Direct identification of 103–107Mo by a rapid chemical separation procedure

1977

Abstract The nuclides 103–107Mo have been identified by means of γ-ray spectroscopy after the separation of molybdenum from fission products of 235U and 239Pu by a rapid chemical procedure. Half-lives of 67.5 ± 1.5 s for 103Mo, 59.4 ± 0.8 s for 104Mo, 36.7 ± 1.0 s for 105Mo, 8.4 ± 0.5 s for 106Mo and 3.5 ± 0.5 s for 107Mo have been determined and the main γ-lines were assigned to the decay of these isotopes. Some evidence for 108Mo with a half-life ≤2 s has also been obtained.

Chemical procedureChemical separationFission productsPolymers and PlasticsIsotopeChemistryMolybdenumMaterials ChemistryAnalytical chemistrychemistry.chemical_elementNuclideSpectroscopyJournal of Inorganic and Nuclear Chemistry
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Decay properties of neutron-rich niobium isotopes

1976

The decay of neutron-rich niobium isotopes in the mass region $A\ensuremath{\simeq}100$ has been investigated by $\ensuremath{\gamma}$-ray singles and $\ensuremath{\gamma}$-$\ensuremath{\gamma}$ coincidence measurements. The isotopes were produced by thermal-neutron induced fission of $^{235}\mathrm{U}$, $^{239}\mathrm{Pu}$, and $^{249}\mathrm{Cf}$, and niobium was separated from fission-product mixtures with an automated chemical procedure. Isomerism was found in the even-mass niobium isotopes with the following half-lives: 1.5 and 3.1 sec for $^{100}\mathrm{Nb}$, 1.3 and 4.3 sec for $^{102}\mathrm{Nb}$, and 0.8 and 4.8 sec for $^{104}\mathrm{Nb}$. Half-lives and $\ensuremath{\gamma}$ rays…

Chemical procedureNuclear reactionPhysicsNuclear and High Energy PhysicsZirconiumIsotopeFissionAstrophysics::High Energy Astrophysical PhenomenaNiobiumchemistry.chemical_elementChemical separationNuclear physicschemistryNeutronAtomic physicsPhysical Review C
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Inhibitoren der Korrosion 24 (1) - Zur Vergleichbarkeit der Abhängigkeit der Korrosion und Korrosionsinhibierung von der Chloridionen- und Inhibitork…

1979

Die Abhangigkeit der „unter Standardbedingungen” im Schuttelversuch ohne und mit Inhibitoren ermittelten O2-Aufnahmegeschwindigkeit von der Chloridionenkonzentration und der Menge an Eisenpulver wird ermittelt. Ergebnis: die von uns bisher eingehaltenen Standardbedingungen vermitteln an Hand der Schutz werte ein qualitativ verlasliches Bild uber die Inhibitorwirksamkeit. Die Vergleichbarkeit der im Schuttelversuch mit DAB 6-Eisenpulver ermittelten Werte mit den im Schuttelversuch mit 1405-Stahlblechen gefundenen Werten wird durch Versuche mit 1405-Stahlblechraspel abgesichert. Die Korrosionsrate phosphatisierter Stahlbleche 1405 wird durch Inhibitoren mit Phosphonsauregruppen wirksam unterd…

ChemistryMechanical EngineeringMetals and AlloysGeneral MedicineChlorideSurfaces Coatings and FilmsStandard procedureTrustworthinessMechanics of MaterialsMaterials ChemistrymedicineEnvironmental ChemistrySteel platesNuclear chemistrymedicine.drugMaterials and Corrosion/Werkstoffe und Korrosion
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