Search results for "CHOP"

Electrodermal and phasic heart rate responses in the Guilty Actions Test: comparing guilty examinees to informed and uninformed innocents.

2007

The present mock-crime study concentrated on the validity of the Guilty Actions Test (GAT) and the role of the orienting response (OR) for differential autonomic responding. N=105 female subjects were assigned to one of three groups: a guilty group, members of which committed a mock-theft; an innocent-aware group, members of which witnessed the theft; and an innocent-unaware group. A GAT consisting of ten question sets was administered while measuring electrodermal and heart rate (HR) responses. For informed participants (guilty and innocent-aware), relevant items were accompanied by larger skin conductance responses and heart rate decelerations whereas irrelevant items elicited HR accelera…

Psychopathological predictors of suicide in patients with major depression during a 5-year follow-up.

2001

SummaryObjective. It is widely known that the risk of suicide is higher in cases of major depressive disorders in comparison to the general population. The purpose of this study was to examine which psychopathologic symptoms during the index episode are predictors for an increased risk of suicide in the further course of major depression.Method. Mortality data were determined from a prospective study of 280 patients with major depression (DSM-III-R, single episode or recurrent) during a follow-up period of 5 years. The predictive power of different depressive symptoms including psychotic symptoms for suicide risk was investigated.Results.Patients who committed suicide(N = 16)during the foll…

Prevalence and pattern of cognitive impairment in systemic lupus erythematosus patients with and without overt neuropsychiatric manifestations

2001

The prevalence and pattern of cognitive impairment in systemic lupus erythematosus (SLE) patients with (NPSLE) and without (nSLE) overt neuropsychiatric manifestations were investigated. Fifty-two nSLE patients, 23 NPSLE patients and 27 healthy controls were evaluated with a battery of standardized neuropsychological and psychological tests. Disease duration, disease activity index, and current corticosteroid therapy were collected. Cognitive impairment was identified in 14 (26.9%) and in 12 (52.2%) of subjects with nSLE and NPSLE, respectively. Both SLE groups showed a significant impairment compared with controls on tasks assessing verbal and non-verbal long-term memory, and visuoconstruc…

Anticipatory effects of food exposure in women diagnosed with bulimia nervosa.

2002

Objective. To investigate cephalic phase responses (CPRs) in women diagnosed with bulimia nervosa and to test the assumption that eating disordered individuals respond with more marked CPRs and higher increases in psychophysiological arousal to the presentation of food cues. Method. Thirteen female inpatients diagnosed with bulimia nervosa were compared to 15 non-eating disordered female volunteers. Participants were exposed to their preferred binge food in a single laboratory session with the possibility to eat immediately after the exposure trial. Results. The results show greater salivation responses to food exposure and lower sympathetic arousal in patients diagnosed with bulimia nervos…

Lung nodule 25 years after lobectomy - recurrence of bronchial carcinoid

2020

OBJECTIVE Introduction: Bronchopulmonary (BP) carcinoids are low and intermediate grade tumors, seen in adults between fourth to sixth decade, where no clear association with tobacco smoking is established. Most often they are sporadic lesions (95%). Half of patients have no symptoms and the tumor is incidentally found on a chest x- ray. BP carcinoids have a good prognostic, however there is a risk of distant metastasis and the recurrences are frequent. Therefore a crucial role of vigilant follow- up, extending far beyond 5 years. PATIENTS AND METHODS Case presentation: We report a case of 73 years old women, with history of recurrent pulmonary infections, and positive family history for lu…

Maintenance of weight loss after obesity treatment: is continuous support necessary?

2002

Abstract Objective: This study examined outcome differences of 109 obese subjects, who participated in a 10-week cognitive-behavioral inpatient treatment followed by either a weight maintenance program or a follow-up period without professional support. Methods: Self-rated weight loss, eating behaviors, and general psychopathology were assessed several months before treatment, when subjects were admitted, at discharge, and at the 6-, 12-, and 18-month follow-ups. Structured interviews for mental disorders and eating pathology were conducted additionally. Results: The mean weight of the sample at baseline was 127 kg. Weight loss of the total sample amounted to 8.0 kg (6.3%) and was completel…

Alemtuzumab (Campath-1H) and CHOP chemotherapy as first-line treatment of peripheral T-cell lymphoma: results of a GITIL (Gruppo Italiano Terapie Inn…

2007

To evaluate in a prospective multicenter trial the feasibility and clinical efficacy of the combination of alemtuzumab (Campath-1H) with the cyclophosphamide/doxorubicin/vincristine/prednisone (CHOP) regimen (CHOP-C) as the primary treatment for patients with peripheral T-cell lymphoma (PTCL), between January 2003 and December 2005, 24 consecutive patients with PTCL entered the study and received 8 CHOP courses. Alemtuzumab was added at 30 mg subcutaneously at day −1 initially to the first 4 courses (4 patients), and then to all 8 courses (20 patients). Complete remission (CR) was achieved in 17 (71%) patients, 1 had partial remission, and 6 had stable/progressive disease. At a median follo…

Does the Interpersonal Model Generalize to Obesity Without Binge Eating?

2016

The interpersonal model has been validated for binge eating disorder (BED), but it is not yet known if the model applies to individuals who are obese but who do not binge eat. The goal of this study was to compare the validity of the interpersonal model in those with BED versus those with obesity, and normal weight samples. Data from a sample of 93 treatment-seeking women diagnosed with BED, 186 women who were obese without BED, and 100 controls who were normal weight were examined for indirect effects of interpersonal problems on binge eating psychopathology mediated through negative affect. Findings demonstrated the mediating role of negative affect for those with BED and those who were o…

2018

AbstractBackgroundThe value of the nosological distinction between non-affective and affective psychosis has frequently been challenged. We aimed to investigate the transdiagnostic dimensional structure and associated characteristics of psychopathology at First Episode Psychosis (FEP). Regardless of diagnostic categories, we expected that positive symptoms occurred more frequently in ethnic minority groups and in more densely populated environments, and that negative symptoms were associated with indices of neurodevelopmental impairment.MethodThis study included 2182 FEP individuals recruited across six countries, as part of the EUropean network of national schizophrenia networks studying G…

Uso problemático del smartphone: el papel de los Cinco Grandes, la Tríada Oscura y la impulsividad

2021

Abstract. Este estudio examinó las relaciones entre los rasgos de personalidad de los cinco grandes (extraversión, afabilidad, neuroticismo, responsabilidad y apertura a la experiencia), la tríada oscura (maquiavelismo, psicopatía y narcisismo), la impulsividad y el uso problemático del smartphone. Doscientos dos participantes (52.48% hombres), con edades comprendidas entre los 18 y los 58 años, completaron el Ten-Item Personality Inventory, la Smartphone Addiction Scale, el Dirty Dozen y la escala de impulsividad de Plutchik. Los análisis de correlación mostraron que el uso problemático del smartphone estaba significativamente asociado a la extraversión, el neuroticismo, la impulsividad y …