Search results for "CHRONIC DISEASE"
showing 10 items of 792 documents
Positioning the principles of precision medicine in care pathways for allergic rhinitis and chronic rhinosinusitis â A EUFOREA-ARIA-EPOS-AIRWAYS IC…
2017
Precision medicine (PM) is increasingly recognized as the way forward for optimizing patient care. Introduced in the field of oncology, it is now considered of major interest in other medical domains like allergy and chronic airway diseases, which face an urgent need to improve the level of disease control, enhance patient satisfaction and increase effectiveness of preventive interventions. The combination of personalized care, prediction of treatment success, prevention of disease and patient participation in the elaboration of the treatment plan is expected to substantially improve the therapeutic approach for individuals suffering from chronic disabling conditions. Given the emerging dat…
Cellul�re Immunreaktionen gegen�ber homologen leberspezifischen Antigenen (HLP) bei chronischen Leberentz�ndungen
1974
Es wird eine Zweiphasentechnik des Leukocyten-Migrations-Inhibitionstestes beschrieben und zum Nachweis einer cellularen Immunreaktion gegenuber Leberantigenen bei chronisch-entzundlichen Lebererkrankungen eingesetzt. Mit dieser Technik wurde bei 85% der Patienten mit hypergammaglobulinamischer Verlaufsform einer chronisch-aktiven Hepatitis und 42% der Patienten mit aktiv fortschreitenden kryptogenen Lebercirrhosen eine Migrationshemmung nachgewiesen. Lebergesunde Kontrollen zeigten keine, Patienten mit dem Zustand nach Hepatitis und chronisch-persistierender Hepatitis selten eine Leukocytenmigrationsinhibition gegenuber leberspezifischen Antigenen. 17% der Patienten mit chronisch-aktiver H…
Adaptive treatment of anemia on hemodialysis patients: A reinforcement learning approach
2011
The aim of this work is to study the applicability of reinforcement learning methods to design adaptive treatment strategies that optimize, in the long-term, the dosage of erythropoiesis-stimulating agents (ESAs) in the management of anemia in patients undergoing hemodialysis. Adaptive treatment strategies are recently emerging as a new paradigm for the treatment and long-term management of the chronic disease. Reinforcement Learning (RL) can be useful to extract such strategies from clinical data, taking into account delayed effects and without requiring any mathematical model. In this work, we focus on the so-called Fitted Q Iteration algorithm, a RL approach that deals with the data very…
Variables Determining Higher Home Care Effectiveness in Patients with Chronic Cardiovascular Disease
2022
The aim of this cross-sectional study was to analyze the variables that influence the effectiveness of home care in patients with chronic cardiovascular disease and their informal caregivers. The study was conducted in 193 patients and their 161 informal caregivers. The study used the WHOQOL-BREF Quality of Life Questionnaire, the health behavior inventory questionnaire (HBI), the Camberwell assessment of need short appraisal schedule (CANSAS) and the hospital anxiety and depression scale–modified (HADS–M) version. Spearman’s rank correlation coefficient test and logistic regression were used for analyses. Analysis of patients revealed an association between home care effe…
Risk stratification tools to predict future hospital admissions in elderly people. Application, development and implementation in the Valencian Healt…
2017
La presente tesis se enmarca en un escenario caracterizado por una población que cada vez vive más años y en la que el porcentaje de personas mayores es progresivamente más alto. De forma adicional, el aumento de la prevalencia de las enfermedades crónicas (EC) supone un importante impacto sobre los sistemas sanitarios dado que éstas son la principal causa de muerte a nivel mundial y, en muchos casos, están asociadas a situaciones de dependencia y a la necesidad de cuidados de larga duración. Con el objetivo de llevar a cabo un abordaje más efectivo de las enfermedades asociadas al envejecimiento y a la cronicidad los sistemas asistenciales deberían sufrir un cambio de paradigma en el que s…
Precision Medicine for Chronic Diseases: Focus on Lifestyle Changes
2022
Virtually all chronic diseases are sustained by lifestyle factors [...]
Coping strategies of Italian and Portuguese mothers in response to a child’s chronic or oncological disease: a cross-cultural study
2013
Background: A child’s chronic or oncological disease is a stressful condition for parents, that may affect the adaptive management helpful for warranting the child’s wellbeing to a disease. Particularly, this study focuses on the possible connections between the variable “culture” and parental strategies to cope with child’s severe disease, by a comparison between Italian and Portuguese mothers. Design and Methods: This research inquires differences and cross-cultural elements among the coping strategies used by Italian and Portuguese mothers of child with chronic or oncological disease. Participants are two mothers’ groups: 59 Italian mothers (M=37,7; SD=4,5) and 36 Portuguese mothers (M=3…
Evaluating the impact of external job mobility on three health outcomes: a longitudinal study of the IDEWE cohort of Belgian workers
2022
There is large debate in the literature about the relationship between job mobility and health. This thesis contributes to this topic by estimating the impact of work mobility on either cardiovascular, musculoskeletal or neuropsychological diseases in a longitudinal study on a sample of Belgian workers followed-up for seven-years. The occurrence of such diseases was assessed through medication use as proxy. In the first part of this thesis, the focus was on CVD and MSD diseases. To this aim, a logistic regression model for autocorrelated data with repeated measures was applied (while controlling for the time-variant and time-invariant confounders). This longitudinal model was adequate to ta…
Centre d'Educació Especial Auxilia. Un model d'atenció acadèmica domiciliària
2011
This article describes a pioneering experience in education - Auxilia Centre for Special Education. This centre provides continuity for the education of children affected by physical disabilities, chronic illness or psychiatric illness and who, because of their illness, are forced to stay at home for certain periods without being able to assume standardized travel to the school at which they are enrolled. The Centre gives them personal and individualized academic service at home to enable their development.
Stercorary aseptic peritonitis due to diastatic caecal perforation: Computed tomography findings
2006
Caecal perforation is a complication secondary to colon obstruction. It may present with insidious clinical features and may be associated with chronic constipation. The event may become severe due to the peritonitic development. We present a case of caecal perforation associated with sub-occlusive carcinoma of the left colon and hypotonic colitis caused by chronic lavative abuse, demonstrated with Computed Tomography.