Search results for "CHRONIC DISEASES"

Influenza vaccination in high-risk groups: a revision of existing guidelines and rationale for an evidence-based preventive strategy.

2016

Summary Influenza, an infectious respiratory disease, is one of the main causes of excess winter deaths (EWDs) in Europe. Annual flu epidemics are associated with high morbidity and mortality rates, especially among the elderly, those with underlying health conditions and pregnant women. Health Care Workers (HCWs) are also considered at high risk of both contracting influenza and spreading the virus to vulnerable patients. During the 2014/2015 season, the excess winter mortality rates observed in countries of the northern hemisphere (EuroMOMO network) and in Italy (+13%) were strongly related to the intensity of influenza circulation. Influenza vaccination is the most important public healt…

Self-Perceived Health, Objective Health, and Quality of Life among People Aged 50 and Over: Interrelationship among Health Indicators in Italy, Spain…

2020

It is well known that self-perceived health (SPH), even if it is a subjective health indicator, is significantly associated with objective health and quality of life (QoL) in the general population. Whether it can be considered an indicator of cognitive functioning and quality of life in the elderly is still an open issue. This study used a data-driven approach to investigate the interrelationship among SPH, non-communicable diseases (NCDs), QoL, and cognitive functioning to answer this question. The study sample included information about 12,831 people living in Italy, Spain, and Greece, extracted from the Survey on Health, Aging, and Retirement in Europe, in the year 2015. The additive Ba…

Proceedings of the Symposium “Updates in Pathobiology: Causality and Chance in Ageing, Age-related diseases and Longevity”

2017

The Symposium "Updates in Pathobiology: Causality and Chance in Ageing, Age-related diseases and Longevity" was held on March 24 in Palermo, 2017 (Sala delle Capriate, Palazzo Chiaramonte Steri), the day after exams for obtaining the title of PhD in Molecular Medicine and Biotechnology XXIX, Cycle (Coordinator Prof. Calogero Caruso) by seven PhD candidates; four of them have been awarded the title of Doctor Europaeus.

ADHERENCE TO A MEDITERRANEAN DIET AND PHYSICAL FUNCTION DECLINE AMONG OLDER PERSONS

2011

ANTIAGING STRATEGIES

2010

Risk stratification tools to predict future hospital admissions in elderly people. Application, development and implementation in the Valencian Healt…

2017

La presente tesis se enmarca en un escenario caracterizado por una población que cada vez vive más años y en la que el porcentaje de personas mayores es progresivamente más alto. De forma adicional, el aumento de la prevalencia de las enfermedades crónicas (EC) supone un importante impacto sobre los sistemas sanitarios dado que éstas son la principal causa de muerte a nivel mundial y, en muchos casos, están asociadas a situaciones de dependencia y a la necesidad de cuidados de larga duración. Con el objetivo de llevar a cabo un abordaje más efectivo de las enfermedades asociadas al envejecimiento y a la cronicidad los sistemas asistenciales deberían sufrir un cambio de paradigma en el que s…

Precision Medicine for Chronic Diseases: Focus on Lifestyle Changes

2022

Virtually all chronic diseases are sustained by lifestyle factors [...]

IFT46 Expression in the Nasal Mucosa of Primary Ciliary Dyskinesia Patients: Preliminary Study

2021

Este artículo se encuentra disponible en la siguiente URL: https://journals.sagepub.com/doi/pdf/10.1177/2152656721989288 Background: Primary ciliary dyskinesia (PCD) is characterised by an imbalance in mucociliary clearance leading to chronic respiratory infections. Cilia length is considered to be a contributing factor in cilia movement. Recently, IFT46 protein has been related to cilia length. Therefore, this work aims to study IFT46 expression in a PCD patients cohort and analyse its relationship with cilia length and function, as it was not previously described. Materials and methods: The expression of one intraflagellar transport (IFT46) and two regulating ciliary architecture (FOXJ1 a…

GLP-1 Receptor agonists and diabetic kidney disease: A call of attention to nephrologists

2020

Type 2 diabetes mellitus (T2DM) represents the main cause of chronic kidney disease (CKD) and end-stage renal disease (ESKD), and diabetic kidney disease (DKD) is a major cause of morbidity and mortality in diabetes. Despite advances in the nephroprotective treatment of T2DM, DKD remains the most common complication, driving the need for renal replacement therapies (RRT) worldwide, and its incidence is increasing. Until recently, prevention of DKD progression was based around strict blood pressure (BP) control, using renin–angiotensin system blockers that simultaneously reduce BP and proteinuria, adequate glycemic control and control of cardiovascular risk factors. Glucagon-like peptide-1 r…

High-Speed Video Microscopy for Primary Ciliary Dyskinesia Diagnosis: A Study of Ciliary Motility Variations with Time and Temperature

2021

Este artículo se encuentra disponible en la siguiente URL: https://www.mdpi.com/2075-4418/11/7/1301 Este artículo de investigación pertenece al número especial "Progress in Diagnosing and Managing Primary Ciliary Dyskinesia". Primary ciliary dyskinesia (PCD) is a rare disease resulting from a defect in ciliary function that generates, among other issues, chronic upper and lower respiratory tract infections. European guidelines recommend studying ciliary function (pattern (CBP) and frequency (CBF)), together with characteristic clinical symptoms, as one of the definitive tests. However, there is no “gold standard”. The present study aims to use high-speed video microscopy to describe how CBF…