Search results for "CIAS"
showing 10 items of 23066 documents
Analysis of salivary detection of P16INK4A and RASSF1A promoter gene methylation and its association with oral squamous cell carcinoma in a Colombian…
2019
Background Epigenetic factors play a fundamental role in the etiopathogenesis of oral squamous cell carcinoma (OSCC). This study evaluated if salivary detection of P16INK4A/RASSF1A gene promoter methylation might be linked to the clinical/histological features of OSCC in a Colombian population. Material and Methods Methylation-specific polymerase chain reaction (MSP-PCR) was used to detect the methylation frequency of P16INK4A/RASSF1A genes in DNA obtained from whole saliva collected of 40 healthy controls (HC) and 43 OSCC patients. Determination of the clinical performance of MSP-PCR assay was based on standard algorithms derived from two-way contingency table analysis. The association of …
SMOS Level-2 Soil Moisture Product Evaluation in Rain-Fed Croplands of the Pampean Region of Argentina
2016
A field campaign was carried out to evaluate the Soil Moisture (SM) MIR-SMUDP2 product (v5.51) generated from the data of the Microwave Imaging Radiometer using Aperture Synthesis (MIRAS) aboard the Soil Moisture and Ocean Salinity (SMOS) mission. The study area was the Pampean Region of Argentina, which was selected because it is a vast area of flatlands containing quite homogeneous rain-fed croplands, which are considered SMOS nominal land uses and hardly affected by radio-frequency interference contamination. Transects of ground handheld SM measurements were performed using ThetaProbe ML2x probes within four Icosahedral Snyder Equal Area Earth (ISEA) grid nodes, where permanent SM statio…
A Pluto-like radius and a high albedo for the dwarf planet Eris from an occultation
2011
The dwarf planet Eris is a trans-Neptunian object with an orbital eccentricity of 0.44, an inclination of 44 degrees and a surface composition very similar to that of Pluto. It resides at present at 95.7 astronomical units (1ĝ€‰au is the Earth-Sun distance) from Earth, near its aphelion and more than three times farther than Pluto. Owing to this great distance, measuring its size or detecting a putative atmosphere is difficult. Here we report the observation of a multi-chord stellar occultation by Eris on 6 November 2010 ut. The event is consistent with a spherical shape for Eris, with radius 1,163±6 kilometres, density 2.52±0.05 grams per cm 3 and a high visible geometric albedo,. No nitro…
Un assemblage inhabituel d’insectivores au Miocène inférieur du Sud-Ouest de l’Europe : les talpidés et les dimylidés du bassin de Ribesalbes–Alcora …
2019
The Miocene record of talpids and dimylids in south-western Europe is very scarce. In the present work, we study for the first time the talpids and complete the description of the dimylids, already started with a new species of the genus Plesiodimylus from the Ribesalbes–Alcora Basin (MN4, lower Aragonian, early Miocene) by Crespo et al. (2018). The talpids recovered inRibesalbes–Alcora comprise themost common Desmanodon daamsi and Desmanella fejfari, for which the last known occurrence is recorded here. The dimylids comprise the species Plesiodimylus ilercavonicus, which expands the biostratigraphic record of the genus and species and has been found in a new site. On the other hand, we dis…
A tough travesía: Mobility constraints among late Holocene Patagonian hunter-gatherers through oxygen stable isotopes in enamel and water sources
2020
Central-eastern North Patagonia is characterized by a severe environmental fragmentation due to the scarce and heterogeneous distribution of fresh water. The main local wet zones, the Negro and Colorado river valleys in the North and the Somuncura Foothills in the South are separated by a large and harsh dry land, the travesia. In this paper, we assess the effects of this environmental fragmentation in the mobility of the Late Holocene hunter-gatherers through the analysis of the stable isotopes of oxygen in both enamel and water sources. We analyzed the δ18O of the enamel carbonate of 64 human teeth from 42 individuals from the Negro River valley (n = 30) and the Somuncura Foothills (n = 1…
The genomic history of the Iberian Peninsula over the past 8000 years
2019
We assembled genome-wide data from 271 ancient Iberians, of whom 176 are from the largely unsampled period after 2000 BCE, thereby providing a high-resolution time transect of the Iberian Peninsula. We document high genetic substructure between northwestern and southeastern hunter-gatherers before the spread of farming. We reveal sporadic contacts between Iberia and North Africa by ~2500 BCE and, by ~2000 BCE, the replacement of 40% of Iberia's ancestry and nearly 100% of its Y-chromosomes by people with Steppe ancestry. We show that, in the Iron Age, Steppe ancestry had spread not only into Indo-European-speaking regions but also into non-Indo-European-speaking ones, and we reveal that pre…
Continental-scale temperature variability during the past two millennia
2013
Past global climate changes had strong regional expression. To elucidate their spatio-temporal pattern, we reconstructed past temperatures for seven continental-scale regions during the past one to two millennia. The most coherent feature in nearly all of the regional temperature reconstructions is a long-term cooling trend, which ended late in the nineteenth century. At multi-decadal to centennial scales, temperature variability shows distinctly different regional patterns, with more similarity within each hemisphere than between them. There were no globally synchronous multi-decadal warm or cold intervals that define a worldwide Medieval Warm Period or Little Ice Age, but all reconstructi…
Tectonic evolution of the northern Austral-Magallanes basin in the Southern Patagonian Andes from provenance analysis
2019
We studied the northern tip of the Austral-Magallanes basin in the Southern Patagonian Andes, between the Buenos Aires Lake and the Mayer River at 46°35′ SL and 48°35′ SL, respectively. Proposed objectives were: i) to differentiate Mesozoic-Cenozoic tectonostratigraphic units and, ii) to characterize the different deformational events that took place in the area linked to a variable regional geodynamic context. Sandstones provenance analysis was performed on the Aptian - Albian compressive retroarc deposits and Cenozoic foreland deposits. Studied samples were classified using tectonic discrimination diagrams which show: i) for Cretaceous rocks a dominant sediment source from a recycled orog…
The metamorphic rocks of the Nunatak Viedma in the Southern Patagonian Andes: Provenance sources and implications for the early Mesozoic Patagonia-An…
2019
The Nunatak Viedma within the Southern Patagonian Icefield has been considered as a volcanic center based on its geomorphologic features, despite the fact that field explorations by Eric Shipton determined its metamorphic nature 70 years ago. We carried out fieldwork to characterize this isolated outcrop and performed the first U-Pb dating in detrital zircons from the basement rocks located inside the Southern Patagonian Icefield. We recognized very-low grade metamorphic rocks, corresponding principally to metapelites and metapsammites, and scarce metabasites. Detrital zircons in three metapsammitic samples (composite group of 240 grains) yielded prominent age population peaks at ∼1090, ∼96…
Change in dominance determines herbivore effects on plant biodiversity
2018
Herbivores alter plant biodiversity (species richness) in many of the world’s ecosystems, but the magnitude and the direction of herbivore effects on biodiversity vary widely within and among ecosystems. One current theory predicts that herbivores enhance plant biodiversity at high productivity but have the opposite effect at low productivity. Yet, empirical support for the importance of site productivity as a mediator of these herbivore impacts is equivocal. Here, we synthesize data from 252 large-herbivore exclusion studies, spanning a 20-fold range in site productivity, to test an alternative hypothesis—that herbivore-induced changes in the competitive environment determine the response …