Search results for "CID"

Combined Use of Structure Analysis, Studies of Molecular Association in Solution, and Molecular Modelling to Understand the Different Propensities of…

2021

The arrangement of hydroxyl groups in the benzene ring has a significant effect on the propensity of dihydroxybenzoic acids (diOHBAs) to form different solid phases when crystallized from solution. All six diOHBAs were categorized into distinctive groups according to the solid phases obtained when crystallized from selected solvents. A combined study using crystal structure and molecule electrostatic potential surface analysis, as well as an exploration of molecular association in solution using spectroscopic methods and molecular dynamics simulations were used to determine the possible mechanism of how the location of the phenolic hydroxyl groups affect the diversity of solid phases formed…

Effect of different processing techniques and presence of antioxidant on the chitosan film performance

2022

In the last two decades, the naturally occurring polysaccharides have gained great attention because of their potential applications in different sectors, for example, from food to biomedical sectors. Chitosan is a cationic polysaccharide with good transparency, and currently, it has been considered also as suitable material for the formulation film and coating in cultural heritage protection. In this work, the chitosan films (Ch), with and without natural antioxidant such as citric acid (CA), are formulated considering two different processing techniques: (i) conventional solvent casting and (ii) compression molding, that is an unconventional method for this polysaccharide, giving the poss…

Résistances aux herbicides : au Nord, c’étaient les Laiterons !

2016

SPEGESTAD; Contexte - Après des échecs de désherbage de laiteron épineux à l’aide d’herbicides inhibiteurs de l’ALS (groupe HRAC B) en culture d’endives, l’hypothèse de la présence d’une résistance à ces herbicides a été étudiée. étude - Des tests biologiques avec un herbicide du groupe B (rimsulfuron) ont été effectués sur des populations provenant de parcelles « à problème ». Le gène de l’ALS a également été séquencé afin de rechercher la présence de mutations causant une résistance aux herbicides inhibiteurs de l’ALS dans ces populations. résultats - Les tests biologiques ont montré l’existence d’une résistance au rimsulfuron dans les trois parcelles étudiées. Des mutations au codon 197 …

Gestión de proyectos: antecedentes y consecuentes en el contexto del proyecto y de la organización

2020

En los entornos actuales, caracterizados por altos niveles de competitividad e incertidumbre, las organizaciones se han enfocado en desarrollar sus actividades a través de proyectos, orientados al logro de los objetivos estratégicos. La gestión de proyectos [Project Management (PM)], se refiere a la aplicación de conocimientos, habilidades, herramientas, técnicas, métodos y competencias, a las actividades de los proyectos, con el objetivo alcanzar el éxito en el desempeño de los mismos. En este sentido, la PM, ha adquirido una alta relevancia, por el impacto que genera en la competitividad de las empresas y en el desarrollo económico de los países. A nivel científico, se han logrado avances…

Discovery of a new class of sortase a transpeptidase inhibitors to tackle gram-positive pathogens: 2-(2-phenylhydrazinylidene)alkanoic acids and rela…

2016

A FRET-based random screening assay was used to generate hit compounds as sortase A inhibitors that allowed us to identify ethyl 3-oxo-2-(2-phenylhydrazinylidene)butanoate as an example of a new class of sortase A inhibitors. Other analogues were generated by changing the ethoxycarbonyl function for a carboxy, cyano or amide group, or introducing substituents in the phenyl ring of the ester and acid derivatives. The most active derivative found was 3-oxo-2-(2-(3,4dichlorophenyl)hydrazinylidene)butanoic acid (2b), showing an IC50 value of 50 µM. For a preliminary assessment of their antivirulence properties the new derivatives were tested for their antibiofilm activity. The most active compo…

La sospensione del processo esecutivo

2012

Le riforme del 2005 - 2006 e del 2009 hanno dato, probabilmente, luogo ad una evoluzione concettuale dell’istituto della sospensione del processo esecutivo, dall’originaria forma “speculare” alle sospensioni del processo di cognizione verso un modello affine ai provvedimenti cautelari anticipatori. L’indagine muove da un esame dei precedenti storici dell’istituto, dal codice di procedura civile del 1865, seguendo la sua evoluzione (anche con riferimento ai progetti di riforma poi abbandonati) fino al codice del 1940 ed alle successive riforme.

LACTOBACILLI IN SOURDOUGH FERMENTATION: A REVIEW

2007

Sourdough technology is widely used; it is employed in bread making and for the production of cakes. Sourdough is characterized by a complex microbial ecosystem, mainly represented by lactic acid bacteria and yeasts, whose fermentation confers to the resulting bread its characteristic features such as palatability and high sensory quality. Investigation of the microbial composition of sourdough is relevant in order to determine the potential activities of sourdough microorganisms. This review focuses on the role of the most important group of sourdough fermenting bacteria that consists of lactobacilli; species that belong to the Lactobacillus genus are the main responsible of flavor develop…

Preliminary Investigation of Biogenic Amines in Type I Sourdoughs Produced at Home and Bakery Level

2022

During a survey for isolating sourdough lactic acid bacteria (LAB), 20 dough samples produced at the bakery level (BL) or home-made (HM) were collected. An enzyme-based colorimetric method revealed a total biogenic amines (BAs) concentration in the range 41.4–251.8 ppm for six (three BL and three HM) sourdoughs characterised by unpleasant odours. Eight BAs generally investigated in foods were identified and quantified from these six samples by ultra-high performance liquid chromatography tandem mass spectrometry (UHPLC–MS/MS). Only one HM sample contained almost all analysed BAs. Tryptamine was exclusively detected in HM sourdoughs (0.71–24.1 ppm). Putrescine, tryptamine, …

Approccio multiplo per l’indagine del microbiota dominante negli impasti acidi tradizionali siciliani

2011

Assessing risk perception over recidivist traffic offenders from a multi-group approach: how gendered could it be?

2022

ABSTRACT Objective: The core aim of this study was to examine the predictive role of demographic, psychosocial and driving features of Spanish drivers on their risk perception over recidivist traffic offenders, focusing on gender as a key differentiating factor. Method: For this cross-sectional study, it was analyzed the data gathered from a nationwide sample of 1,711 licensed drivers from the 17 regions of Spain (49% females, 51% males) with a mean age of 40.07 years, responding to a telephone-based interview on road safety issues. Demographic, driving-related and psychosocial factors were comparatively analyzed through robust tests and a bias-corrected MGSEM (Multi-Group Structural Equati…