Search results for "CID"
showing 10 items of 19479 documents
O prozie Šejli Šehabović - na marginesach dyskursu wojennego
2020
The collection of Šehabović’s stories Priće - żeński rod, mnoźina is an important voice in the discussion on the situation of women in post-war Bośnia. An artistically interesting idea of a juxtaposition of female voices, accompanied by representatives of otherdiscriminated groups in society (gays), allowed the Bosnian author to face current and socialiy important problems. It is a faithful literaturę with a deeply anti-war language. Narrative Solutions, the type of heroes and the way of their presentation brings Śejla Śehabović’s prose closer to women’s writing (żeńsko pismo), and far away from the heroic paradigm dominating in Bosnia-Herzegovinan’s war discourse.
Accidents du travail dans l’UE-15 et méthodes d’apprentissage automatique
2020
Les méthodes d’apprentissage automatique ont été utilisées comme outil de prédiction dans denombreux domaines, mais leur utilisation en santé et sécurité au travail est relativement nouvelle.C’est la raison pour laquelle, il serait intéressant d’utiliser ces méthodes dans la prévision desaccidents du travail, sur les données d’enquêtes européennes sur les conditions de travail. L’objectifde ce travail est de tester les performances des techniques d’apprentissage automatique dans lamodélisation et la prédiction d’accidents du travail. A cette fin, nous utiliserons trois modèles :(les forêts aléatoires) (RF), Support Vector Machine (SVM), modèle logistique. Nous observonsque, la performance d…
Using machine learning on tree-ring data to determine the geographical provenance of historical construction timbers
2023
Funder: Bavarian Climate Research Network (BayKliF)
Changing epidemiology of human brucellosis, Germany, 1962-2005
2007
This endemic occupational disease has become a foodborne and travel-associated zoonosis primarily affecting Turkish immigrants.
Divergent Patterns and Trends in Breast Cancer Incidence, Mortality and Survival Among Older Women in Germany and the United States
2020
Background: Breast cancer treatment has changed tremendously over the last decades. In addition, the use of mammography screening for early detection has increased strongly. To evaluate the impact of these developments, long-term trends in incidence, mortality, stage distribution and survival were investigated for Germany and the United States (US). Methods: Using population-based cancer registry data, long-term incidence and mortality trends (1975&ndash
DIAGSOL Development of a new functional marker for B-triketone herbicides exposure in agricultural soils
2017
International audience; The-triketone herbicides are maize selective herbicides that have been largely applied in replacement of atrazine, banned in Europe in 2004. Their mode of action lays on the inhi- bition of the p-hydroxyphenylpyruvate dioxygenase (HPPD), a key enzyme of the carotenoid biosynthesis.In recent studies, we showed that within the soil bacterial community, many microorganisms possess a functional HPPD enzyme involved in tyrosine metabolism. These ”non-target or- ganisms” harbor the target of the-triketone herbicides and consequently may be affected in response to its exposure. From this point of view, the bacterial community harboring the hppd gene might be a relevant mark…
Acid–base properties of functionalised tripodal polyamines and their interaction with nucleotides and nucleic acids
2010
Novel, highly positively charged tripodal polyamines with appended heterocyclic moieties revealed an intriguing panel of protonation species within the biologically relevant range. Studied compounds bind nucleotide monophosphates by mostly electrostatic interactions but only the imidazole analogue showed selectivity toward UMP in respect to other nucleotides. Strong binding of all the studied compounds to both ds-DNA and ds-RNA is to some extent selective toward the latter, showing rather rare RNA over DNA preference.
Hydrogen isotopes (δ2H) of polyunsaturated fatty acids track bioconversion by zooplankton
2022
1. Organisms at the base of aquatic food webs synthesize essential nutrients, such as omega-3 polyunsaturated fatty acids (n-3 PUFA), which are transferred to consumers at higher trophic levels. Many consumers, requiring n-3 long-chain (LC) PUFA, such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have limited ability to biosynthesize them from the essential dietary precursor α-linolenic acid (ALA) and thus rely on dietary provision of LC-PUFA. 2. We investigated LC-PUFA metabolism in freshwater zooplankton using stable hydrogen isotopes (δ2H) of fatty acids as tracers. We conducted feeding experiments with the freshwater keystone grazer Daphnia to quantify changes in the δ2…
Economic and Life Cycle Analysis of Passive and Active Monitoring of Ozone for Forest Protection
2021
At forest sites, phytotoxic tropospheric ozone (O3) can be monitored with continuously operating, active monitors (AM) or passive, cumulative samplers (PM). For the first time, we present evidence that the sustainability of active monitoring is better than that of passive sensors, as the environmental, economic, and social costs are usually lower in the former than in the latter. By using data collected in the field, environmental, social, and economic costs were analyzed. The study considered monitoring sites at three distances from a control station in Italy (30, 400, and 750 km), two forest types (deciduous and Mediterranean evergreen), and three time windows (5, 10, and 20 years of moni…
Dipeptidyl Enoates As Potent Rhodesain Inhibitors That Display a Dual Mode of Action
2015
Dipeptidyl enoates were prepared through a high-yielding two-step synthetic route. They have a dipeptidic structure with a 4-oxoenoate moiety as a warhead with multiple reactive sites. Dipeptidyl enoates were screened against rhodesain and human cathepsins B and L, and were found to be potent and selective inhibitors of rhodesain. Among them (S,E)-ethyl 5-((S)-2-{[(benzyloxy)carbonyl]amino}-3-phenylpropanamido)-7-methyl-4-oxooct-2-enoate (6) was the most potent, with an IC50 value of 16.4 nm and kinact/Ki=1.6×106 m−1 s−1 against rhodesain. These dipeptidyl enoates display a reversible mode of inhibition at very low concentrations and an irreversible mode at higher concentrations. Inhibition…