Search results for "CIM"

showing 10 items of 1625 documents

Influence of Refraction on Tonometric Readings After Photorefractive Keratectomy and Laser Assisted In Situ Keratomileusis

2000

PURPOSE To determine the decrease of Goldmann tonometry after photorefractive keratectomy (PRK) and laser assisted in situ keratomileusis (LASIK) according to refraction prior to surgery. METHODS Prospective simultaneous comparative case series of 53 myopic eyes (53 patients) that underwent PRK and 50 (50 patients) that underwent LASIK using the Summit Excimed SVS plus (Summit Technology, Inc., Walthan, MA, U.S.A.). PRK and LASIK were subdivided by refractive error into two subgroups of more than or less than -5 diopters (D). Central tonometric readings were taken prior to surgery and 12 months after surgery. RESULTS In LASIK and PRK subgroups of more than -5 D, 85.7% (24) and 69.6% (24), r…

AdultMaleRefractive errormedicine.medical_specialtyAdolescentgenetic structuresmedicine.medical_treatmentKeratomileusis Laser In SituKeratomileusisRefraction OcularPhotorefractive KeratectomyTonometry OcularOphthalmologyMyopiaHumansMedicinePostoperative PeriodProspective StudiesIntraocular PressureDioptrebusiness.industryReproducibility of ResultsLASIKGlaucomaMiddle Agedmedicine.diseaseLaser assistedRefractioneye diseasesPhotorefractive keratectomyGoldmann tonometryOphthalmologyFemaleLasers Excimersense organsbusinessCornea
researchProduct

Reproducibility of digital image analysis for measuring corneal haze after myopic photorefractive keratectomy.

1997

Purpose To evaluate the usefulness of digital image analysis for quantifying corneal haze by determining the reproducibility of its measurements at the corneal plane. Methods In a prospective study, 20 randomly selected eyes that had undergone myopic photorefractive keratectomy were photographed focusing the slit beam on their anterior corneal surface. Each photograph was examined using computer image analysis techniques that detect the edge of the reticular pattern of the image. Quantification of the difference between two areas, treated and adjacent untreated cornea, each containing 3,750 pixels with a resolution of 256 gray levels, was performed. Intra-analyzer variation was determined b…

AdultMaleRefractive errormedicine.medical_specialtyHazeMaterials sciencegenetic structuresCoefficient of variationmedicine.medical_treatmentImage processingPhotorefractive KeratectomyCorneaOpticsPostoperative ComplicationsCorneaOphthalmologymedicineImage Processing Computer-AssistedMyopiaHumansProspective StudiesReproducibilityCorneal Hazebusiness.industryReproducibility of ResultsMiddle Agedmedicine.diseaseeye diseasesPhotorefractive keratectomyOphthalmologymedicine.anatomical_structureFemaleLasers Excimersense organsbusinessAmerican journal of ophthalmology
researchProduct

Direct Objective Quantification of Corneal Haze after Excimer Laser Photorefractive Keratectomy for High Myopia

1996

Purpose: The purpose of the study is to measure regional distribution differences in corneal haze after excimer laser photorefractive keratectomy for high myopia. Methods: The authors developed computerized gradient edge detectors with which were analyzed digitized anterior slit-lamp photographs of 40 eyes, an average of 21.0 plus or minus 14.5 weeks after photorefractive keratectomy for high myopia (−6 to −22 diopters). A treated area and an adjacent untreated area on the anterior corneal surface, each containing six regions, were quantified, and the difference was correlated with various parameters. Results: Mean differences between scarred and clear areas for haze grade 0.5, 1.0, 2.0, 3.…

AdultMaleRefractive errormedicine.medical_specialtyHazegenetic structuresmedicine.medical_treatmentExcimerPhotorefractive KeratectomyCorneaCorneal OpacityOphthalmologyCorneaImage Processing Computer-AssistedMyopiamedicineHumansDioptreCorneal Hazebusiness.industryMiddle Agedmedicine.diseaseeye diseasesPhotorefractive keratectomyOphthalmologymedicine.anatomical_structureFemaleLasers Excimersense organsbusinessFollow-Up StudiesAblation zoneOphthalmology
researchProduct

Mesopic contrast sensitivity function after excimer laser photorefractive keratectomy.

2002

ABSTRACT PURPOSE: To evaluate contrast sensitivity under mesopic conditions in patients who had undergone uncomplicated excimer laser photorefractive keratectomy (PRK) for myopia. METHODS: Monocular contrast sensitivity function was measured with the Stereo Optical ?A.C.T. chart in 26 patients who had received PRK using the Nidek EC-5000 excimer laser system. Mean preoperative refractive error was -6.23 ? 1.69 D (range, -4.00 to -8.25 D); postoperatively, mean refractive error was -0.36 ? 0.58 D (range, -0.75 to +0.50 D). Contrast sensitivity function was measured 6 months after surgery using four different chart luminances: 85, 5.0, 2.5, and 0.1 cd/m2, the first being a photopic level and …

AdultMaleRefractive errormedicine.medical_specialtyMaterials scienceLightMesopic visionmedicine.medical_treatmentmedia_common.quotation_subjectVisual AcuityEmmetropiaRefraction OcularExcimerPhotorefractive KeratectomyContrast SensitivityOpticsOphthalmologyMyopiamedicineHumansContrast (vision)media_commonExcimer laserbusiness.industrymedicine.diseaseeye diseasesPhotorefractive keratectomyOphthalmologyFemaleLasers ExcimerSurgerybusinessPhotopic vision
researchProduct

Excimer laser photorefractive keratectomy for high myopia

1995

Abstract One hundred and thirty-three eyes of 103 patients had photorefractive keratectomy with a slit scan mode excimer laser for myopia ranging from −6.00 to −22.00 diopters (D). The epithelium was removed with 20% ethanol, and the ablation was done with a tapered profile surrounding the optical zone. Patients were divided into two groups based on preoperative myopia: Group A, −6.00 D to −12.00 D (88 eyes); Group B, −12.50 D to −22.00 D (45 eyes). In Group A, mean preoperative refraction was −9.59 ± 1.79 D. Mean postoperative refraction was −0.29 ± 1.47 D at one month, −0.85 ± 1.68 D at three months, −1.17 ± 2.04 D at six months, and −0.56 ± 0.74 D at one year. Anterior stromal haze was g…

AdultMaleRefractive errormedicine.medical_specialtygenetic structuresCorneal Stromamedicine.medical_treatmentEye diseaseVisual AcuityRefraction OcularExcimerPhotorefractive KeratectomyEpitheliumCorneaVision disorderCorneal OpacityOphthalmologyMyopiamedicineHumansIntraocular PressureDioptreExcimer laserbusiness.industryMiddle AgedPrognosismedicine.diseaseAblationeye diseasesSensory SystemsPhotorefractive keratectomyOphthalmologyFemaleLasers ExcimerSurgerysense organsmedicine.symptombusinessJournal of Cataract and Refractive Surgery
researchProduct

Methodological considerations to determine the effect of exercise on brain-derived neurotrophic factor levels.

2015

Objectives: Physical exercise up-regulates brain-derived neurotrophic factor (BDNF) in the brain and blood. However, there is yet no consensus about the adequate blood processing conditions to standardize its assessment. We aimed to find a reliable blood sample processing method to determine changes in BDNF due to exercise. Design and methods: Twelve healthy university students performed an incremental cycling test to exhaustion. At baseline, immediately after exercise, and 30 and 60 min of recovery, venous blood was drawn and processed under different conditions, i.e. whole blood, serum coagulated for 10 min and 24 h, total plasma, and platelet-free plasma. BDNF concentration was measured …

AdultMaleSerummedicine.medical_specialtyHemoconcentrationClinical BiochemistryPhysical exerciseHemoconcentraciónPlasmaEnzyme-linked immunosorbent assayNeurotrophic factorsInternal medicinePlasma sanguineoSurveys and QuestionnairesMedicineHumansPlateletEducación físicaExerciseWhole bloodBrain-derived neurotrophic factorBlood Specimen Collectionbusiness.industryBrain-Derived Neurotrophic FactorGeneral MedicineVenous bloodHemoconcentrationWhole bloodEndocrinologyHomogeneousbusinessEnergy MetabolismClinical biochemistry
researchProduct

In vitro production of GHB in blood and serum samples under various storage conditions

2011

Abstract The in vitro production of GHB was observed in freshly collected, untreated whole blood samples using glass BD-Vacutainers and polypropylene S-monovettes. GHB concentrations were determined daily over a period of one week and after 3, 6 and 9 weeks again. Furthermore, the GHB concentration in 40 untreated random whole blood samples stored at 4 °C for a longer period of time (10 samples 12 month, 10 samples 24 month and 20 samples 36 month) was also determined. For comparison, the in vitro production of GHB in freshly collected and prepared serum samples was observed. GHB serum concentrations were determined three times over a period of one week and once again after six weeks. Sampl…

AdultMaleTime FactorsHydroxybutyratesPoison controlIn Vitro TechniquesGas Chromatography-Mass SpectrometrySpecimen HandlingPathology and Forensic MedicineForensic ToxicologyHumansMedicineSample preparationWhole bloodChromatographybusiness.industryTemperatureForensic toxicologygamma-Hydroxybutyric acidMiddle AgedSerum samplesIn vitroAnesthesiaFemaleGas chromatography–mass spectrometrybusinessLawmedicine.drugForensic Science International
researchProduct

Local Gingival Blood Flow at Healthy and Inflamed Sites Measured by Laser Doppler Flowmetry

2006

This investigation aimed to: 1) develop a method to obtain reproducible laser Doppler flow readings (LDFRs) at the gingiva of the maxillary front teeth; 2) evaluate regional gingival blood flow (GBF) in healthy gingiva by laser Doppler flowmetry; 3) compare hand-held LDFR (H-LDFR) with splint LDFR (S-LDFR); and 4) monitor changes in GBF in experimental gingivitis (EG) and chronic gingivitis (CG).The LDFR, gingival index (GI), and plaque index (PI) were measured at 13 gingival sites (teeth #6 to #11) in 10 healthy volunteers (five males and five females), 23 to 34 years of age, over a period of 12.5 +/- 3.27 days employing a partial-mouth EG model and in 11 patients (three males and eight fe…

AdultMaleToothbrushingCuspidPlaque indexGingivaDentistryGingivitisHealthy volunteersLaser-Doppler FlowmetryMaxillaHumansMedicineLaser doppler flowbusiness.industryDental Plaque IndexReproducibility of ResultsEquipment DesignBlood flowMiddle AgedLaser Doppler velocimetryGingivitisIncisorGingival indexRegional Blood FlowChronic DiseasePeriodonticsFemalePeriodontal Indexmedicine.symptombusinessChronic gingivitisJournal of Periodontology
researchProduct

Prognostic Relevance of Cardiorespiratory Fitness as Assessed by Submaximal Exercise Testing for All-Cause Mortality: A UK Biobank Prospective Study

2020

Objective: To investigate if the inverse associations of cardiorespiratory fitness (CRF) with all-cause and cardiovascular mortality in the general population vary among individuals who are at different pre-test risk. Patients and Methods: CRF was assessed through submaximal bike tests in 58,892 participants aged 40-69 years who completed baseline questionnaires between January 1, 2006 and December 31, 2010 in the UK Biobank study. Participants were categorized into risk categories, which determined allocation to an individualized bike protocol. These were “minimal risk (1)”, “small risk (2)” and “medium risk (3)” groups (i.e., those who cycled at 50%, 35% of predicted maximal workload and …

AdultMaleUK Biobankmedicine.medical_specialtyDatabases FactualPopulationsubmaximal testRisk AssessmentMetabolic equivalentrisk predictionInterquartile rangeCause of DeathInternal medicinemedicineHumansProspective StudiesProspective cohort studyeducationAgedBiological Specimen Bankseducation.field_of_studycardiorespiratory fitnessFramingham Risk Scorebusiness.industryHazard ratioCardiorespiratory fitnessGeneral MedicineMiddle AgedPrognosisUnited KingdomCardiorespiratory FitnessCardiovascular DiseasesExercise Testall-cause mortalityFemaleRisk assessmentbusinessMayo Clinic Proceedings
researchProduct

Transcranial Doppler diagnosis of cerebral vasospasm following subarachnoid haemorrhage: correlation and analysis of results in relation to the age o…

1994

A retrospective analysis was undertaken to determine whether cerebral vasospasm following subarachnoid haemorrhage (SAH) correlates with the age of patients. For at least 3 weeks after bleeding 80 subjects underwent very close follow-up with clinical examination and transcranial Doppler records of the blood velocities within the basal cerebral arteries. Firstly a correlation between measured maximal mean blood flow velocities and age was made. Secondly, according to their age and the maximum of recorded mean velocities (v), the patients were divided into groups as follows: age 55 years or less, age more than 55 years; and maximum velocity v190 cm/s, 90 cm/sv2120 cm/s, 120 cm/sv3160 cm/s, v4…

AdultMaleUltrasonography Doppler TranscranialCerebral arteriesAneurysm RupturedDrug Administration ScheduleCerebral vasospasmMedicineHumanscardiovascular diseasesNeuroradiologyAgedRetrospective StudiesDose-Response Relationship Drugbusiness.industryVascular diseaseAge FactorsVasospasmIntracranial AneurysmLaser Doppler velocimetryMiddle AgedSubarachnoid Hemorrhagemedicine.diseasenervous system diseasesTranscranial Dopplermedicine.anatomical_structureIschemic Attack TransientAnesthesiaCerebrovascular CirculationSurgeryFemaleNimodipineNeurology (clinical)businessBlood Flow VelocityArteryFollow-Up StudiesActa neurochirurgica
researchProduct