Search results for "CLASSIFICATION"
showing 10 items of 29475 documents
Serum omega-3 fatty acids are not associated with age-related macular degeneration
2012
Revue non indexée dans le JCR.; International audience; Evaluation of: Kabasawa S, Mori K, Horie-Inoue K et al. Associations of cigarette smoking but. not serum fatty acids with age-related macular degeneration in a Japanese population. Ophthalmology 118(6), 1082–1088 (2011). Age-related macular degeneration (AMD) is the leading cause of visual impairment in the elderly. in developed countries. Risk factors for AMD are classified into endogenous nonmodifiable. factors, including genetics and environmental factors such as smoking and dietary habits. Both. epidemiological and experimental studies suggest that dietary omega-3 long-chain fatty acids. would participate to prevent from the develo…
On the use of multi-temporal series of COSMO-SkyMed data for LANDcover classification and surface parameter retrieval over agricultural sites
2011
The objective of this paper is to report on the activities carried out during the first year of the Italian project “Use of COSMO-SkyMed data for LANDcover classification and surface parameters retrieval over agricultural sites” (COSMOLAND), funded by the Italian Space Agency. The project intends to contribute to the COSMO-SkyMed mission objectives in the agriculture and hydrology application domains.
New genera, species and records of Phaneropterinae (Orthoptera, Phaneropteridae) from sub-Saharan Africa
2015
The results of the study of many specimens preserved in different European museums are reported. The tribe Terpnistrini Brunner von Wattenwyl, 1878 is resurrected. The distribution of the following species is enhanced: Pardalotaasymmetrica Karsch, 1896, Diogenadenticulata Chopard, 1954, Diogenafausta (Burmeister, 1838), Plangiopsisadeps Karsch, 1896, Poreuomenasanghensis Massa, 2013 and Tylopsiscontinua (Walker, 1869). Further, for their peculiar characteristics, two African representatives of the American genus Symmetropleura Brunner von Wattenwyl, 1878 are included in two new genera: Symmetrokarschiaafricana (Brunner von Wattenwyl, 1878), comb. n. and Symmetroraggeadirempta (Karsch, 1889)…
Phytochemical investigation of the needles of Abies nebrodensis (Lojac.) Mattei
2019
Abies nebrodensis (Lojac.) Mattei (Pinaceae) is a species living in a very small population only in a confined area of Sicily. In this study, the dichloromethane extract of the leaves was analyzed. Apart from three already known metabolites namely dehydroabietic acid; maltol; and rheosmin, previously detected in other species of Abies, a lanostane derivative was isolated. Its chemical structure was elucidated by means of extensive spectroscopic methods.
A novel microtubule de-stabilizing complementarity-determining region C36L1 peptide displays antitumor activity against melanoma in vitro and in vivo
2015
AbstractShort peptide sequences from complementarity-determining regions (CDRs) of different immunoglobulins may exert anti-infective, immunomodulatory and antitumor activities regardless of the specificity of the original monoclonal antibody (mAb). In this sense, they resemble early molecules of innate immunity. C36L1 was identified as a bioactive light-chain CDR1 peptide by screening 19 conserved CDR sequences targeting murine B16F10-Nex2 melanoma. The 17-amino acid peptide is readily taken up by melanoma cells and acts on microtubules causing depolymerization, stress of the endoplasmic reticulum and intrinsic apoptosis. At low concentrations, C36L1 inhibited migration, invasion and proli…
Synthesis and biological evaluation of novel peptidomimetics as rhodesain inhibitors
2016
Novel rhodesain inhibitors were developed by combining an enantiomerically pure 3-bromoisoxazoline warhead with a 1,4-benzodiazepine scaffold as specific recognition moiety. All compounds were proven to inhibit rhodesain with Ki values in the low-micromolar range. Their activity towards rhodesain was found to be coupled to an in vitro antitrypanosomal activity, with IC50 values ranging from the mid-micromolar to a low-micromolar value for the most active rhodesain inhibitor (R,S,S)-3. All compounds showed a good selectivity against the target enzyme since all of them were proven to be poor inhibitors of human cathepsin L. Novel rhodesain inhibitors were developed by combining an enantiomeri…
Detection of natural killer T cells in mice infected with Rickettsia conorii.
2013
Little information is available regarding the role of natural killer T (NKT) cells during the early stage of Rickettsia conorii infection. Herein, C3H/HeN mice were infected with the Malish 7 strain of R. conorii. Splenocytes from these mice were analysed in the early stage of the infection by flow cytometry and compared with uninfected controls. Our results showed an increase in NKT cells in infected mice. Additionally, NKT interleukin (IL)-17(+) cells increased three days after infection, together with a concurrent decrease in the relative amount of NKT interferon (IFN)-γ(+) cells. We also confirmed a higher amount of NK IFN-γ(+) cells in infected mice. Taken together, our data showed tha…
The Effect of Mechanocatalytic Pretreatment on the Structure and Depolymerization of Willow
2020
In this study, the effect of a mechanocatalytic pretreatment on the structure of willow and sugar release from pretreated willow was explored. In the mechanocatalytic approach, the pretreatment consists of solvent-free impregnation with sulfuric acid and a mechanical treatment with ball milling. Willow sawdust and pretreated samples were analyzed with field emission scanning electron microscope and X-ray diffraction. The products in the sugar solution were determined as the total reducing sugars with the 3,5-dinitrosalicylic acid method and monosaccharides with capillary electrophoresis. According to the results, milling increased the sugar production, depending on the sulfuric acid load. T…
Risk map of transmission of urogenital schistosomiasis by Bulinus truncatus (Audouin, 1827) (Mollusca Gastropoda, Bulinidae) in Spain and Portugal
2019
Mapa del riesgo de contraer schistosomiasis urogenital provocada por Bulinus truncatus (Audouin, 1827) (Mollusca Gastropoda, Bulinidae) en España y Portugal Se da a conocer el mapa de la distribución geográfica de Bulinus truncatus en España y Portugal en el que se recopilan las localidades históricas y actuales, que coincide con el mapa del riesgo de contraer schistosomiasis urogenital provocada por este caracol de agua dulce. Se revisan las muestras de esta especie depositadas en el Museu de Ciències Naturals de Barcelona y en el Museo de Ciencias Naturales de Madrid, así como datos propios, incluidas algunas aportaciones inéditas. Este mapa permitirá conocer el área óptima de esta especi…
Selection of spawning substratum by European river lampreys (Lampetra fluviatilis) in experimental tanks
2014
The selection of spawning substratum by the river lamprey (Lampetra fluviatilis) was studied in two experimental tanks with different flow conditions. In both tanks, four gravel sizes mixed with 15% sand were available to the test animals. In the tank with the lower current speed, lampreys selected in favour of the finest (2–8 mm) gravel size available against gravel sizes 4–20 mm and 8–40 mm. Selection was also significantly different in the tank with higher current speed where selection against the medium-sized substratum (4–20 mm) was evident, but there were no differences between selection for gravel sizes 2–8 mm, 2–40 mm and 8–40 mm relative to availability. Substratum selection and ob…