Search results for "CLEO"

showing 10 items of 4423 documents

How challenging RADseq data turned out to favor coalescent-based species tree inference. A case study in Aichryson (Crassulaceae)

2022

Analysing multiple genomic regions while incorporating detection and qualification of discordance among regions has become standard for understanding phylogenetic relationships. In plants, which usually have comparatively large genomes, this is feasible by the combination of reduced-representation library (RRL) methods and high-throughput sequencing enabling the cost effective acquisition of genomic data for thousands of loci from hundreds of samples. One popular RRL method is RADseq. A major disadvantage of established RADseq approaches is the rather short fragment and sequencing range, leading to loci of little individual phylogenetic information. This issue hampers the application of coa…

0106 biological sciences570clustering threshold selectionInferenceLocus (genetics)Computational biologyBiologyCrassulaceaedata bias010603 evolutionary biology01 natural sciencesGenomeCoalescent theoryspecies tree inference03 medical and health scienceslocus filteringGeneticscoalescent-based summary methodCluster analysisMolecular BiologyEcology Evolution Behavior and SystematicsSelection (genetic algorithm)Phylogeny030304 developmental biology0303 health sciencesGenomePhylogenetic treeHigh-Throughput Nucleotide SequencingGenomicsRADseq500 Naturwissenschaften und Mathematik::570 Biowissenschaften; Biologie::570 Biowissenschaften; BiologieTree (data structure)
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Phylogenomics Identifies an Ancestral Burst of Gene Duplications Predating the Diversification of Aphidomorpha

2019

Aphids (Aphidoidea) are a diverse group of hemipteran insects that feed on plant phloem sap. A common finding in studies of aphid genomes is the presence of a large number of duplicated genes. However, when these duplications occurred remains unclear, partly due to the high relatedness of sequenced species. To better understand the origin of aphid duplications we sequenced and assembled the genome of Cinara cedri, an early branching lineage (Lachninae) of the Aphididae family. We performed a phylogenomic comparison of this genome with 20 other sequenced genomes, including the available genomes of five other aphids, along with the transcriptomes of two species belonging to Adelgidae (a close…

0106 biological sciences:Informàtica::Aplicacions de la informàtica::Bioinformàtica [Àrees temàtiques de la UPC]Gene duplicationAphidomorphaLineage (evolution)010603 evolutionary biology01 natural sciencesGenomeSyntenyDNA sequencingFilogèniaEvolution Molecular03 medical and health sciencessequencia genómicaSpecies SpecificityPhylogenomicsGene duplicationBioinformaticaGeneticsAdelgidaeAnimalsMolecular BiologyEcology Evolution Behavior and SystematicsDiscoveriesPhylogeny030304 developmental biologySegmental duplication0303 health sciencesAphidbiologyWhole Genome SequencingGene Expression Profilinggene duplicationfood and beveragesHigh-Throughput Nucleotide SequencingAfidomorfabiochemical phenomena metabolism and nutritionbiology.organism_classificationaphidsGenòmicaGene Expression RegulationEvolutionary biologyAphidsInsect ProteinsGenèticaMolecular Biology and Evolution
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The Spodoptera exigua ABCC2 Acts as a Cry1A Receptor Independently of its Nucleotide Binding Domain II

2019

ABC proteins are primary-active transporters that require the binding and hydrolysis of ATP to transport substrates across the membrane. Since the first report of an ABCC2 transporter as receptor of Cry1A toxins, the number of ABC transporters known to be involved in the mode of action of Cry toxins has increased. In Spodoptera exigua, a mutation in the SeABCC2 gene is described as genetically linked to resistance to the Bt-product XentariTM. This mutation affects an intracellular domain involved in ATP binding, but not the extracellular loops. We analyzed whether this mutation affects the role of the SeABCC2 as a functional receptor to Cry1A toxins. The results show that Sf21 cells express…

0106 biological sciencesCell SurvivalHealth Toxicology and Mutagenesislcsh:MedicineReceptors Cell SurfaceATP-binding cassette transporterSpodopteraSpodopteraToxicologymedicine.disease_causeBt resistance01 natural sciencesArticleCell LineHemolysin Proteins03 medical and health sciencesBacterial Proteinsmode of actionGTP-Binding ProteinsATP hydrolysismedicineAnimalsReceptor030304 developmental biology0303 health sciencesMutationBacillus thuringiensis ToxinsbiologyChemistryfungilcsh:Rheterologous expressionTransporterbiology.organism_classificationMultidrug Resistance-Associated Protein 2Cell biologyEndotoxins010602 entomologyCyclic nucleotide-binding domainSf21 cellstruncated transporterInsect ProteinsHeterologous expressionMultidrug Resistance-Associated ProteinsToxins
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Changes in carbohydrate metabolism in Plasmopara viticola-infected grapevine leaves.

2011

International audience; The oomycete Plasmopara viticola is responsible for downy mildew, a severe grapevine disease. In infected grapevine leaves, we have observed an abnormal starch accumulation at the end of the dark period, suggesting modifications in starch metabolism. Therefore, several complementary approaches, including transcriptomic analyses, measurements of enzyme activities, and sugar quantification, were performed in order to investigate and to understand the effects of P. viticola infection on leaf starch and-to a larger extent-carbohydrate metabolism. Our results indicate that starch accumulation is associated with an increase in ADP-glucose pyrophosphorylase (AGPase) activit…

0106 biological sciencesChlorophyllPhysiologyStarchenzymatic activityhexosesbeta-AmylaseplantGlucose-1-Phosphate Adenylyltransferasetranscriptomic analyse01 natural sciencesinvertasechemistry.chemical_compoundphytopathogenGene Expression Regulation PlantVitisTrehalaseOligonucleotide Array Sequence Analysis0303 health sciencesbiologyfood and beveragesStarchGeneral MedicineEnzymesBiochemistryOomycetesRNA PlantPlasmopara viticolaCarbohydrate metabolism03 medical and health sciencesPlasmopara viticolaADP-glucose pyrophosphorylasePolysaccharidesVignecarbohydrate metabolism[SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular Biology[ SDV.BBM ] Life Sciences [q-bio]/Biochemistry Molecular Biologytrehalose030304 developmental biologyPlant Diseasesphotosynthesisbiology.organism_classificationtrehalaseTrehaloseEnzyme assayPlant LeavesInvertasechemistryVitis viniferabiology.proteinDowny mildewfungialpha-AmylasesphysiopathologyAgronomy and Crop Science010606 plant biology & botany
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The genome sequencing of an albino Western lowland gorilla reveals inbreeding in the wild

2013

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License.-- et al.

0106 biological sciencesConservation geneticsMalegenotype phenotype correlationGorillaComputingMilieux_LEGALASPECTSOFCOMPUTINGarginineGenoma humà01 natural sciencesOculocutaneous albinism type 4single nucleotide polymorphismAlbinismegenetic variabilityGorillaInbreedinggenetic conservationGenetics0303 health sciencesGenomebiologyarticlecopy number variationHigh-Throughput Nucleotide SequencingSLC45A2 geneGenomicszygosityOculocutaneous albinismFloquet de neu (Goril·la)AlbinismFemaleBiotechnologyamino acid substitutionResearch ArticleSLC45A2Gorilla gorilla gorillaHeterozygoteAlbinismMolecular Sequence Datacomparative genomic hybridizationgene sequenceConservation010603 evolutionary biology03 medical and health sciencesWestern lowland gorillabiology.animalmedicineGeneticsheterozygosityAnimalsAmino Acid Sequencegene030304 developmental biologygene identificationWhole genome sequencingnonhumanGorilla gorillaMembrane Transport ProteinsSequence Analysis DNA15. Life on landbiology.organism_classificationmedicine.diseaseGenòmicaData_GENERALMutationbiology.proteinGenèticaoculocutaneous albinismglycineMicrosatellite RepeatsBMC Genomics
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Nested core collections maximizing genetic diversity in Arabidopsis thaliana.

2004

Summary The successful exploitation of natural genetic diversity requires a basic knowledge of the extent of the variation present in a species. To study natural variation in Arabidopsis thaliana, we defined nested core collections maximizing the diversity present among a worldwide set of 265 accessions. The core collections were generated based on DNA sequence data from a limited number of fragments evenly distributed in the genome and were shown to successfully capture the molecular diversity in other loci as well as the morphological diversity. The core collections are available to the scientific community and thus provide an important resource for the study of genetic variation and its …

0106 biological sciencesDNA PlantArabidopsisSingle-nucleotide polymorphismPlant Science01 natural sciencesGenomePolymorphism Single NucleotideDNA sequencing[SDV.GEN.GPL]Life Sciences [q-bio]/Genetics/Plants genetics03 medical and health sciencesArabidopsis[SDV.GEN.GPL] Life Sciences [q-bio]/Genetics/Plants geneticsGenetic variationGeneticsArabidopsis thalianaComputingMilieux_MISCELLANEOUS030304 developmental biologyGenetic associationGenetics0303 health sciencesGenetic diversitybiologyGenetic VariationCell Biology15. Life on landbiology.organism_classificationPhenotypeEvolutionary biologyhuman activitiesGenome Plant010606 plant biology & botanyThe Plant journal : for cell and molecular biology
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High-Quality Genome Assembly and Annotation of the Big-Eye Mandarin Fish (Siniperca knerii)

2020

Abstract The big-eye mandarin fish (Siniperca knerii) is an endemic species of southern China. It belongs to the family Sinipercidae, which is closely related to the well-known North American sunfish family Centrarchidae. Determining the genome sequence of S. knerii would provide a foundation for better examining its genetic diversity and population history. A novel sequenced genome of the Sinipercidae also would help in comparative study of the Centrarchidae using Siniperca as a reference. Here, we determined the genome sequence of S. knerii using 10x Genomics technology and next-generation sequencing. Paired-end sequencing on a half lane of HiSeq X platform generated 56 Gbp of raw data. R…

0106 biological sciencesGene predictionPopulationChinese perchSequence assemblyGenomicsSinipercaQH426-470BiologyGenome sequencing010603 evolutionary biology01 natural sciencesGenome03 medical and health sciencesGenome SizeGeneticsAnimalsSiniperca kneriieducationMolecular BiologyGenome sizeGenetics (clinical)030304 developmental biologyWhole genome sequencing0303 health scienceseducation.field_of_studyGenome assemblyGenome10x GenomicsFishesHigh-Throughput Nucleotide SequencingMolecular Sequence AnnotationGenomicsbiology.organism_classificationGenome ReportEvolutionary biologyG3: Genes|Genomes|Genetics
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Genomic variation in tomato, from wild ancestors to contemporary breeding accessions

2015

[EN] Background: Domestication modifies the genomic variation of species. Quantifying this variation provides insights into the domestication process, facilitates the management of resources used by breeders and germplasm centers, and enables the design of experiments to associate traits with genes. We described and analyzed the genetic diversity of 1,008 tomato accessions including Solanum lycopersicum var. lycopersicum (SLL), S. lycopersicum var. cerasiforme (SLC), and S. pimpinellifolium (SP) that were genotyped using 7,720 SNPs. Additionally, we explored the allelic frequency of six loci affecting fruit weight and shape to infer patterns of selection. Results: Our results revealed a pat…

0106 biological sciencesGermplasm[SDV.SA]Life Sciences [q-bio]/Agricultural sciencesBreeding01 natural sciencesNucleotide diversityDomesticationtomatefréquence des allèlespérouGene FrequencyCherry tomatoequateurSolanum lycopersicumexpression du génomeFruit size genes2. Zero hungerGenetics0303 health sciencesVegetal BiologyGenomebiologytaille du fruitfood and beveragesGenomicsSolanum lycopersicum;Solanum pimpinellifolium;SolCAP array;Origin;Variability;Genome;Fruit size genes;DomesticationSolanum pimpinellifoliumAgricultural sciencesSolCAP arrayGenome PlantResearch ArticleBiotechnologyHeterozygotePolymorphism Single NucleotideEvolution Molecular03 medical and health sciencesOriginGeneticsvariabilité génomique[SDV.BV]Life Sciences [q-bio]/Vegetal BiologyAlleleGenomesVariabilityDomestication030304 developmental biologyGenetic diversityfungiSolanum pimpinellifoliumbiology.organism_classificationFruitaGENETICAFruitSolanumSciences agricolesBiologie végétale010606 plant biology & botanyamélioration des plantes
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Acting locally - affecting globally: RNA sequencing of gilthead sea bream with a mild Sparicotyle chrysophrii infection reveals effects on apoptosis,…

2019

[Background] Monogenean flatworms are the main fish ectoparasites inflicting serious economic losses in aquaculture. The polyopisthocotylean Sparicotyle chrysophrii parasitizes the gills of gilthead sea bream (GSB, Sparus aurata) causing anaemia, lamellae fusion and sloughing of epithelial cells, with the consequent hypoxia, emaciation, lethargy and mortality. Currently no preventive or curative measures against this disease exist and therefore information on the host-parasite interaction is crucial to find mitigation solutions for sparicotylosis. The knowledge about gene regulation in monogenean-host models mostly comes from freshwater monopysthocotyleans and almost nothing is known about …

0106 biological sciencesGillGillsApoptosis01 natural sciencesTranscriptomeSparus aurataGene expression0303 health sciencesHigh-Throughput Nucleotide Sequencingmedicine.anatomical_structureLiverHelminthiasis AnimalMonogeneaBiotechnologyResearch ArticleFish Proteinsanimal structureslcsh:QH426-470lcsh:BiotechnologyFisheriesSpleenBiologyMicrobiologyHost-Parasite Interactions03 medical and health sciencesImmune systemIllumina RNA-seqImmunitylcsh:TP248.13-248.65GeneticsmedicineAutophagyAnimals14. Life underwaterPlatelet activationImmune responseTranscriptomics030304 developmental biologyCell ProliferationSequence Analysis RNASparus aurata Sparicotyle chrysophrii Gills Monogenea Ectoparasites Illumina RNA-seq Transcriptomics Apoptosis Immune responseGene Expression ProfilingAquatic animalSea Breamlcsh:GeneticsGene Expression RegulationPlatyhelminthsSparicotyle chrysophriiEctoparasitesSpleen010606 plant biology & botany
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Genome reduction and potential metabolic complementation of the dual endosymbionts in the whitefly Bemisia tabaci

2015

Background The whitefly Bemisia tabaci is an important agricultural pest with global distribution. This phloem-sap feeder harbors a primary symbiont, “Candidatus Portiera aleyrodidarum”, which compensates for the deficient nutritional composition of its food sources, and a variety of secondary symbionts. Interestingly, all of these secondary symbionts are found in co-localization with the primary symbiont within the same bacteriocytes, which should favor the evolution of strong interactions between symbionts. Results In this paper, we analyzed the genome sequences of the primary symbiont Portiera and of the secondary symbiont Hamiltonella in the B. tabaci Mediterranean (MED) species in orde…

0106 biological sciencesHamiltonellaCandidatus Portiera aleyrodidarum[SDV]Life Sciences [q-bio]Molecular Sequence DataWhiteflyPortiera010603 evolutionary biology01 natural sciencesGenomeHemiptera03 medical and health sciencesMetabolic complementationSymbiosisEnterobacteriaceaeBotanyGeneticsAnimalsAmino AcidsSymbiosisIn Situ Hybridization Fluorescence030304 developmental biology2. Zero hungerGenetics0303 health sciencesEndosymbiontGenomebiologyfungifood and beveragesHigh-Throughput Nucleotide SequencingDNASequence Analysis DNAVitaminsbiochemical phenomena metabolism and nutritionbiology.organism_classificationEnterobacteriaceaeHemipteraWhiteflyComplementationHalomonadaceaeGlobal distribution[INFO.INFO-BI]Computer Science [cs]/Bioinformatics [q-bio.QM]Genome BacterialMetabolic Networks and PathwaysBiotechnologyResearch ArticleBMC Genomics
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