Search results for "COM.E.TA."
showing 10 items of 198 documents
Phage therapy
2013
Bacteriophage therapy, the use of viruses that infect bacteria as antimicrobials, has been championed as a promising alternative to conventional antibiotics. Although in the laboratory bacterial resistance against phages arises rapidly, resistance so far has been an only minor problem for the effectiveness of phage therapy. Resistance to antibiotics, however, has become a major issue after decades of extensive use. Should we expect similar problems after long-term use of phages as antimicrobials? Like antibiotics, phages are often noted to be drivers of bacterial evolution. Should we expect phage-treated pathogens to develop a general resistance to phages over time, a resistance against whi…
Ancient Medicine in the Galenic Corpus: The Story of a Concealment
2021
The paper proposes, starting from some certain or probable allusions (in part. a passage in Galen's Commentary on 'Epidemics' 2, only extant in Arabic translation), but also from some striking omissions ('Ancient medicine' is not mentioned in the history of hygiene that Galen traces out in the central chapters of Thrasybulus), to reconstruct the history of this significant ‘concealment’. This will also be done in the light of the numerous passages in the corpus in which Galen advocates, constantly linking it to Hippocrates, the ideal of medicine that is ‘physiologica’.
Magnaporthe oryzae as an expression host for the production of the unspecific peroxygenase AaeUPO from the basidiomycete Agrocybe aegerita.
2021
Abstract The filamentous fungus Magnaporthe oryzae has the potential to be developed as an alternative platform organism for the heterologous production of industrially important enzymes. M. oryzae is easy to handle, fast‐growing and unlike yeast, posttranslational modifications like N‐glycosylations are similar to the human organism. Here, we established M. oryzae as a host for the expression of the unspecific peroxygenase from the basidiomycete Agrocybe aegerita (AaeUPO). Note, UPOs are attractive biocatalysts for selective oxyfunctionalization of non‐activated carbon‐hydrogen bonds. To improve and simplify the isolation of AaeUPO in M. oryzae, we fused a Magnaporthe signal peptide for pr…
Statistical Adhockeries Are No Criteria for Legal Decisions—The Case of the Expert Medical Report on the Assessment of Urine Specimens Collected Amon…
2019
Pathogenesis of inflammatory bowel disease: transcription factors in the spotlight.
1998
See article on page 477 Dysregulated cytokine production by mucosal lymphocytes and macrophages has been implicated in the pathogenesis of both Crohn’s disease and ulcerative colitis, the two major forms of human inflammatory bowel disease (IBD).1 Over the past few years, various murine models of chronic intestinal inflammation resembling IBD have been discovered which have provided important clues as to the nature of this dysregulation and to its possible treatment with cytokines.2 Thus, in studies of several of the models most closely resembling Crohn’s disease it has been shown that production of large amounts of Th1-type cytokines—for example, interferon γ, by T cells is a major and ess…
Adipose stromal cells promote the transition of colorectal cancer cells toward a mesenchymal-like phenotype
2021
ABSTRACT Colon cancer progression is among the risks that increase with obesity. We have recently unveiled the molecular mechanism by which adipose tissue-released molecules, HGF and IL-6, make colorectal cancer (CRC) cells acquiring mesenchymal traits. Targeting of adipose-derived factors abrogate the metastatic potential of CRC stem cells (CR-CSCs) in obese patients.
Codice commentato delle società
2010
commento art 2251
L'ASSEMBLEA DI S.P.A.: ART. 2363 - 2379 TER COD. CIV., IN CODICE CIVILE COMMENTATO, A CURA DI G. ALPA E V. MARICONDA, IPSOA, II^ ed. (pp. 1376-1484).
2009
commentario di dottrina e giurisprudenza delle relative norme
Жанр комментария в творческом наследии Исмаила Гаспринского
2022
The article deals with the place of the commentary genre in the journalistic heritage of a Crimean Tatar journalist, publisher, and educator, Ismail Gasprinsky. The authors prove that the work of I. Gasprinsky reveals an inclination towards the “journalism of opinion”. One of the leading roles in it is played by the commentary genre, in which the editor and publisher of the Crimean Tatar newspaper, “Perevodchik-Terdzhiman”, expressed his attitude to the pressing problems of our time. The journalistic comments of I. Gasprinsky show us his views on politics, society, religion, education, economy, and journalism, and the variety of rhetorical devices used in the comments demonstrate his journa…
The Scholica Graecarum glossarum and Martianus Capella
2011
The essay takes into examination the entries of the glossary known as 'Scholica Graecarum glossarum' which feature the influence of the 'De nuptiis Philologiae et Mercurii' by Martianus Capella. These entries are a secondary accretion to the original glossary. The comparison between the entries of the 'Scholica' and the commentary to the 'De Nuptiis' by Remigius of Auxerre prove his dependence on the glossary.