Search results for "COMPREHENSIVE"

showing 10 items of 161 documents

Frailty trajectories in community‐dwelling older adults during COVID ‐19 pandemic: The PRESTIGE study

2022

Background Frailty has been recognized as potential surrogate of biological age and relevant risk factor for COVID-19 severity. Thus, it is important to explore the frailty trajectories during COVID-19 pandemic and understand how COVID-19 directly and indirectly impacts on frailty condition. Methods We enrolled 217 community-dwelling older adults with available information on frailty condition as assessed by multidimensional frailty model both at baseline and at one-year follow-up using Multidimensional Prognostic Index (MPI) tools. Pre-frail/frail subjects were identified at baseline as those with MPI score >0.33 (MPI grades 2-3). Frailty worsening was defined by MPI difference between …

COVID-19 community comprehensive geriatric assessment frailty multidimensional prognostic indexFrailtySARS-CoV-2Clinical BiochemistryHumansCOVID-19FemaleIndependent LivingGeneral MedicineGeriatric AssessmentPandemicsBiochemistryAgedEuropean Journal of Clinical Investigation
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The Porto European Cancer Research Summit 2021.

2021

Key stakeholders from the cancer research continuum met in May 2021 at the European Cancer Research Summit in Porto to discuss priorities and specific action points required for the successful implementation of the European Cancer Mission and Europe's Beating Cancer Plan (EBCP). Speakers presented a unified view about the need to establish high‐quality, networked infrastructures to decrease cancer incidence, increase the cure rate, improve patient's survival and quality of life, and deal with research and care inequalities across the European Union (EU). These infrastructures, featuring Comprehensive Cancer Centres (CCCs) as key components, will integrate care, prevention and research acros…

Cancer Researchmedicine.medical_specialty:Otros calificadores::Otros calificadores::/prevención & control [Otros calificadores]infrastructures for translational cancer researchDeclarationTranslational researchContext (language use)comprehensive cancer centresMeeting Reportclinical/prevention trials:profesiones sanitarias::medicina::medicina clínica::medicina de precisión [DISCIPLINAS Y OCUPACIONES]Translational Research Biomedicaloutcomes research:neoplasias [ENFERMEDADES]:Other subheadings::Other subheadings::/prevention & control [Other subheadings]cancer research/care/prevention continuumNeoplasmsPolitical scienceGeneticsmedicineHumansmedia_common.cataloged_instance:Health Occupations::Medicine::Clinical Medicine::Precision Medicine [DISCIPLINES AND OCCUPATIONS]Medicina personalitzadaPrecision MedicineEuropean unionRC254-282media_commongeographySummitgeography.geographical_feature_categoryHealth economics:Natural Science Disciplines::Science::Research::Biomedical Research [DISCIPLINES AND OCCUPATIONS]Neoplasms. Tumors. Oncology. Including cancer and carcinogensGeneral MedicineCancer MissionEuropescience policy:Neoplasms [DISEASES]Medicina - InvestigacióOncologyQuality of LifeCancer researchMolecular MedicineScience policyCàncer - PrevencióOutcomes research:disciplinas de las ciencias naturales::ciencia::investigación::investigación biomédica [DISCIPLINAS Y OCUPACIONES]
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From molecular mechanisms to clinical management of antineoplastic drug-induced cardiovascular toxicity: A translational overview

2019

Significance: Antineoplastic therapies have significantly improved the prognosis of oncology patients. However, these treatments can bring to a higher incidence of side-effects, including the worrying cardiovascular toxicity (CTX). Recent Advances: Substantial evidence indicates multiple mechanisms of CTX, with redox mechanisms playing a key role. Recent data singled out mitochondria as key targets for antineoplastic drug-induced CTX; understanding the underlying mechanisms is, therefore, crucial for effective cardioprotection, without compromising the efficacy of anti-cancer treatments. Critical Issues: CTX can occur within a few days or many years after treatment. Type I CTX is associated…

Cardiovascular toxicityPhysiologymedicine.medical_treatmentAntineoplastic drugClinical BiochemistryAntineoplastic Agents030204 cardiovascular system & hematologyPharmacologyBiochemistryCardiac cellcancer immunotherapy; chemotherapy; ErbB2 inhibitors; oxidative/nitrosative stress; tyrosine kinase inhibitors; vascular endothelial growth factor; Antineoplastic Agents; Cardiotoxicity; Humans; Mitochondria; Oxidation-Reduction03 medical and health scienceschemistry.chemical_compoundErbB2 inhibitors cancer immunotherapy chemotherapy oxidative/nitrosative stress tyrosine kinase inhibitors vascular endothelial growth factor0302 clinical medicinetyrosine kinase inhibitorcancer immunotherapy; chemotherapy; ErbB2 inhibitors; oxidative/nitrosative stress; tyrosine kinase inhibitors; vascular endothelial growth factorChemotherapy; ErbB2 inhibitors; vascular endothelial growth factor; tyrosine kinase inhibitors; oxidative/nitrosative stress; cancer immunotherapyCancer immunotherapytyrosine kinase inhibitorsmedicineHumansChemotherapyMolecular BiologyGeneral Environmental ScienceCardioprotectionComprehensive Invited ReviewsChemotherapyErbB2 inhibitorcancer immunotherapyvascular endothelial growth factorbusiness.industryCell BiologyCardiotoxicityMitochondriaVascular endothelial growth factoroxidative/nitrosative streErbB2 inhibitorschemistry030220 oncology & carcinogenesisGeneral Earth and Planetary SciencesbusinessOxidation-ReductionAfter treatmentoxidative/nitrosative stress
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A multi-criteria evaluation system for arable land resource assessment

2020

This study proposed a multi-criteria evaluation system for arable land resources by combining the soil integrated fertility index (IFI) with a soil cleanliness index (based on heavy metals and metalloid content). A total of 16 typical arable land units in Chongming District, China, were evaluated using the proposed evaluation system based on 104 collected soil samples in 16 towns. The comprehensive soil evaluation scores of arable lands in 16 towns were in the range of 90.7 to 99.2 with a mean of 96.2, indicating that the arable land in all 16 towns was at the level of excellent (≥ 90.0). Lower cleanliness indices had a significant impact on the final evaluation score. In comparison with si…

ChinaEvaluation systemIndex (economics)Soil testarviointimenetelmätintegrated fertility index (IFI)010501 environmental sciencesManagement Monitoring Policy and LawSoil cleanliness index01 natural sciencesArticleArable land resourcemulti-criteria evaluation systemComprehensive soil evaluation scoreraskasmetallitSoilMetals HeavyMulti-criteria evaluation systemcomprehensive soil evaluation scoreheavy metalshedelmällisyys0105 earth and related environmental sciencesGeneral Environmental Science2. Zero hungerarable land resourcebusiness.industrysoil cleanliness indexmaaperänsuojeluHeavy metalsSubsidyAgriculture04 agricultural and veterinary sciencesGeneral Medicine15. Life on landRequisitionPollutionIntegrated fertility index (IFI)6. Clean waterHeavy metalsAgriculture040103 agronomy & agriculture0401 agriculture forestry and fisheriesEnvironmental scienceArable landWater resource managementbusinessEnvironmental MonitoringEnvironmental Monitoring and Assessment
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Key pedagogical principles and their major obstacles as perceived by comprehensive school teachers

2011

The general pedagogical knowledge of teachers is not often investigated in comparison to content knowledge and pedagogical content knowledge. In this article, a more comprehensive outlook on teache...

Class sizeComprehensive schoolArts and Humanities (miscellaneous)Age differencesTeaching methodPedagogyKey (cryptography)Mathematics educationInterpersonal communicationContent knowledgePsychologyEducationLikert scaleTeachers and Teaching
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The multidimensional prognostic index (MPI) for the prognostic stratification of older inpatients with COVID-19: A multicenter prospective observatio…

2021

Background: The topic of prognosis in COVID-19 research may be important in adopting appropriate clinical decisions. Multidimensional prognostic index (MPI) is a frailty assessment tool widely used for stratifying prognosis in older people, but data regarding inpatients, affected by COVID-19, are not available. Objectives: To evaluate whether MPI can predict in-hospital mortality and the admission to intensive care unit (ICU) in older inpatients hospitalized for COVID-19 infection. Methods: In this longitudinal, Italian, multi-center study, older patients with COVID-19 were included. MPI was calculated using eight different domains typical of comprehensive geriatric assessment and categoriz…

Comprehensive geriatric assessment; COVID-19; Frailty; Intensive care unit; Mortality; Multidimensional prognostic index; Prognosis; Aged; Aged 80 and over; Female; Geriatric Assessment; Humans; Italy; Male; Prognosis; Prospective Studies; SARS-CoV-2; COVID-19; InpatientsMaleAgingmedicine.medical_specialtyHealth (social science)Coronavirus disease 2019 (COVID-19)Comprehensive geriatric assessmentintensive care unitArticlePrognostic stratificationlaw.inventionCOVID-19 Multidimensional prognostic index Mortality Intensive care unit Prognosis Frailty Comprehensive geriatric assessment03 medical and health sciences0302 clinical medicinelaw80 and overHumansMedicineProspective Studies030212 general & internal medicineProspective cohort studyGeriatric AssessmentAgedAged 80 and overInpatientsFrailty030214 geriatricsSARS-CoV-2business.industryHazard ratioArea under the curveCOVID-19mortalityIntensive care unitmultidimensional prognostic indexConfidence intervalItalyEmergency medicineFemaleprognosisGeriatrics and GerontologybusinessGerontologyCohort study
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European Integration and Inequality among Countries: A Lifecycle Income Analysis

2012

We analyze the effects of the expansions of the European Union on inequality using an approach based on individuals' lifecycle incomes. This allows us to consider the effect of different rates of growth and survival rates. This differs form the usual analyses of inequality that focus on the evolution of current per capita income for the period. Our results show that inequality in terms of permanent income was substantially less than in current per capita income at the time of all the expansions except those of the last ten years. The results point to the key role of policies that stimulate growth in the less developed countries. With an annual β-convergence of 2% in current income, inequali…

Comprehensive incomeTotal personal incomebusiness.industryGeography Planning and DevelopmentDistribution (economics)International economicsDevelopmentPer capita incomeIncome inequality metricsPermanent income hypothesisIncome distributionEconomicsmedia_common.cataloged_instanceDemographic economicsEuropean unionbusinessmedia_commonReview of International Economics
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INFLUENCE OF THE PROJECT “QUALITATIVE INCLUSIVE EDUCATION FOR SPECIAL NEEDS CHILDREN” ON THE DEVELOPMENT OF INCLUSIVE EDUCATION IN THE PROJECT SCHOOLS

2015

The study „Evaluation of the project influence on the development of inclusive education in project schools” was implemented from 2009 till 2011 in the project “Qualitative inclusive education for special needs children” (Education initiative centre, State Education content centre, Soros Foundation Latvia, more information in: http://www.iic.lv) with the aim to find out whether the project results brought changes in defined inclusive education indicators. The article analyzes how the cooperation of school’s pedagogues in promoting inclusive education in general comprehensive school has improved as a result of the project.

Comprehensive schoolInclusive education; Inclusive school; Index for inclusive education; pedagogues’ cooperation for inclusive educationPolitical sciencePedagogyPrimary educationSpecial needsSpecial educationSOCIETY, INTEGRATION, EDUCATION. Proceedings of the International Scientific Conference
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Parents' role in adolescents' educational expectations

2012

The present study examined the extent to which mothers' and fathers' expectations for their offspring's future education, their level of education, and adolescents' academic achievement predict adolescents' educational expectations. To investigate this, 230 adolescents were examined twice while they were in comprehensive school (in the 7th and 9th grades). Their parents also filled in questionnaires at the same time points. The results showed that high parental expectations concerning their offspring's future education predicted high educational expectations among adolescents and they became more similar in the 9th grade compared to 7th grade. Parents' high level of education predicted both…

Comprehensive schoolOffspringAcademic achievementPsychologySocial psychologyEducational attainmentta515EducationSocial statusDevelopmental psychologyScandinavian journal of educational research
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COMPREHENSIVE TEACHER’S PROFESSIONALISM FOR CONTENT AND LANGUAGE INTEGRATED PROVISION

2019

T opicality of the problem is determined by several factors as well as the amendments on the Education Law and the General Education Law, which provide for a gradual transition to the acquisition of general secondary education in Latvian only, educational content reform and teachers experience to work in an ethnically and linguistically heterogeneous environment. The aim of the study is to analyse comprehensive school teachers theoretical background and practice experience to work in the content and language integrated teaching and learning approach. Because language not a subject only but a mean of acquiring other subjects in the comprehensive school, too, all teachers need theoretical kno…

Comprehensive schoolSecondary educationGradual transitionInterviewMathematics educationlanguageEducational contentLatvianGeneral educationcollaboration; competence; content and language integrated learning (CLIL)PsychologyCompetence (human resources)language.human_languageSOCIETY. INTEGRATION. EDUCATION. Proceedings of the International Scientific Conference
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