Search results for "CONTINUA"
showing 10 items of 362 documents
Two-stage adaptive designs with correlated test statistics.
2005
When performing a trial using an adaptive sequential design, it is usually assumed that the data for each stage come from different units; for example, patients. However, sometimes it is not possible to satisfy this condition or to check whether it is satisfied. In these cases, the test statistics and p-values of each stage may be dependent. In this paper we investigate the type I error of two-stage adaptive designs when the test statistics from the stages are assumed to be bivariate normal. Analytical considerations are performed under the restriction that the conditional error function is constant in the continuation region. We show that the decisions can become conservative as well as an…
Adverse events as potential predictive factors of activity in patients with advanced hepatocellular carcinoma treated with lenvatinib
2021
Background and Aim: Lenvatinib is a standard of care option in first-line therapy of advanced hepatocellular carcinoma (HCC). In the present study, we aim to identify, in patients with HCC treated with lenvatinib, a possible association between occurrence and grading of adverse events (AEs) and outcome. Methods: We performed a retrospective analysis of 606 Japanese and Italian patients treated with lenvatinib in first-line setting and investigated the possible correlation between the onset of AEs, toxicity grade (G) and outcome measures such as overall survival (OS) and progression-free survival (PFS). Results: The appearance of arterial hypertension G ≥ 2 independently predicted prolonged …
Theoretical analysis of the γγ→π0η process
2017
We present a theoretical study of the $\ensuremath{\gamma}\ensuremath{\gamma}\ensuremath{\rightarrow}\ensuremath{\pi}\ensuremath{\eta}$ process from the threshold up to 1.4 GeV in the $\ensuremath{\pi}\ensuremath{\eta}$ invariant mass. For the s-wave ${a}_{0}(980)$ resonance state we adopt a dispersive formalism using a coupled-channel Omn\`es representation, while the d-wave ${a}_{2}(1320)$ state is described as a Breit-Wigner resonance. An analytic continuation to the ${a}_{0}(980)$ pole position allows us to extract its two-photon decay width as ${\mathrm{\ensuremath{\Gamma}}}_{{a}_{0}\ensuremath{\rightarrow}\ensuremath{\gamma}\ensuremath{\gamma}}=0.27(4)\text{ }\text{ }\mathrm{keV}$.
The WKB Approximation
2017
In this chapter we shall develop an important semiclassical method which has come back into favor again, particularly in the last few years, since it permits a continuation into field theory. Here, too, one is interested in nonperturbative methods.
Thermal field theories and shifted boundary Conditions
2014
The analytic continuation to an imaginary velocity of the canonical partition function of a thermal system expressed in a moving frame has a natural implementation in the Euclidean path-integral formulation in terms of shifted boundary conditions. The Poincare' invariance underlying a relativistic theory implies a dependence of the free-energy on the compact length L_0 and the shift xi only through the combination beta=L_0(1+xi^2)^(1/2). This in turn implies that the energy and the momentum distributions of the thermal theory are related, a fact which is encoded in a set of Ward identities among the correlators of the energy-momentum tensor. The latter have interesting applications in latti…
An energy residual-based approach to gradient effects within the mechanics of generalized continua
2012
AbstractGeneralized continua exhibiting gradient effects are addressed through a method grounded on the energy residual (ER)-based gradient theory by the first author and coworkers. A main tool of this theory is the Clausius-Duhem inequality cast in a form differing from the classical one only by a nonstandard extra term, the (nonlocality) ER, required to satisfy the insulation condition (its global value has to vanish or to take a known value). The ER carries in the nonlocality features of the mechanical problem through a strain-like rate field, being the specific nonlocality source, and a concomitant higher-order long-range stress (or microstress) field. The thermodynamic restrictions on …
Analytic continuation and numerical evaluation of the kite integral and the equal mass sunrise integral
2017
We study the analytic continuation of Feynman integrals from the kite family, expressed in terms of elliptic generalisations of (multiple) polylogarithms. Expressed in this way, the Feynman integrals are functions of two periods of an elliptic curve. We show that all what is required is just the analytic continuation of these two periods. We present an explicit formula for the two periods for all values of $t \in {\mathbb R}$. Furthermore, the nome $q$ of the elliptic curve satisfies over the complete range in $t$ the inequality $|q|\le 1$, where $|q|=1$ is attained only at the singular points $t\in\{m^2,9m^2,\infty\}$. This ensures the convergence of the $q$-series expansion of the $\mathr…
Unitarity of Minkowski nonlocal theories made explicit
2021
In this work we explicitly show that the perturbative unitarity of analytic infinite derivative (AID) scalar field theories can be achieved using a modified prescription for computing scattering amplitudes. The crux of the new prescription is the analytic continuation of a result obtained in the Euclidean signature to the Minkowski external momenta. We intensively elaborate an example of a non-local $\phi^4$ model for various infinite derivative operators. General UV properties of amplitudes in non-local theories are discussed.
Helicity Amplitudes of the Lambda(1670) and two Lambda(1405) as dynamically generated resonances
2010
We determine the helicity amplitudes A(1/2) and radiative decay widths in the transition Lambda(1670) -> gamma Y (Y = Lambda or Sigma(0)). The Lambda(1670) is treated as a dynamically generated resonance in meson-baryon chiral dynamics. We obtain the radiative decay widths of the Lambda(1670) to gamma Lambda as 2 +/- 1 keV and to -gamma Sigma(0) as 120 +/- 50 keV. Also, the Q(2)-dependence of the helicity amplitudes A(1/2) is calculated. We find that the K Xi component in the Lambda(1670) structure, mainly responsible for the dynamical generation of this resonance, is also responsible for the significant suppression of the decay ratio Gamma(gamma A)/Gamma(gamma Sigma 0). A measurement of th…
Precise determination of resonance pole parameters through Pad\'e approximants
2014
In this work, we present a precise and model--independent method to extract resonance pole parameters from phase-shift scattering data. These parameters are defined from the associated poles in the second Riemann sheet, unfolded by the analytic continuation to the complex pole using Pad\'e approximants. Precise theoretical parameterizations of pion-pion scattering phase shifts based on once-- and twice-- subtracted dispersion relations are used as input, whose functional form allows us to show the benefit and accuracy of the method. In particular, we extract from these parametrization the pole positions of the $f_0(500)$ at $\sqrt{s}=(453\pm 15) - i(297 \pm 15)$ MeV, the $\rho(770)$ at $\sq…