Search results for "CQ"
showing 10 items of 1801 documents
Stroke Analysis in Padel According to Match Outcome and Game Side on Court
2020
The aim of this study was to analyze the distribution of padel strokes, their effectiveness, direction, and court zone, comparing between the winning and losing pairs in the match and the playing side of the players. The sample included 8441 strokes corresponding to 1055 points out of a total of nine padel matches in the First National Category. The variables analyzed were type of stroke, court area, effectiveness and directions of the strokes, match outcome, and game side. Matches were analyzed through systematic observation. The results showed that the winning pair made a significantly higher percentage of winners, and cross-court smashes and volleys from the offensive zone. In addition, …
SAT0378 Autophagy is Up-Regulated in the Salivary Glands of Primary Sjogren's Syndrome Patients and Correlates with the Focus Score and Disease Activ…
2015
Background Autophagy is now considered as a major regulator in trafficking events that activates innate and adaptive immunity and consistent evidence supports its role in autoimmunity (1). Primary Sjogren9s syndrome (pSS) is a systemic autoimmune disease characterized by infiltration of exocrine glands by T and B cells that, producing chemokines and cytokines, coordinate the chronic inflammatory process. No data on the role of autophagy in pSS are available in humans, although studies in mice demonstrated its involvement in the salivary and lacrimal gland homeostasis (2,3). Objectives We investigated the autophagy process in salivary gland tissue and in peripheral T lymphocytes from pSS pat…
El último intelectual (y 4). Un modelo
2007
Uomini e technai nell'ambiente: tra Arie, acque, luoghi e il Prometeo incatenato
2021
Al centro dell'attenzione di questo studio è la relazione tra uomini e ambiente così come delineata nello scritto ippocratico Arie, acque, luoghi. In effetti, la valutazione di alcuni termini chiave presenti nell'opera ippocratica permette di individuare una relazione complessa, basata sulla reciproca osmosi e interazione tra l'essere umano e l'ambiente in cui vive, una relazione segnata da una terminologia che ne mette in luce il rapporto di somiglianza e di adattamento reciproco. Una particolare riflessione, in tal senso, merita la parte conclusiva del trattato ippocratico (considerato qui come unitario), in cui è descritta l'attitudine sociale (ethos) dell'essere umano, relativamente più…
The human first cell cycle: impact on implantation.
2013
The morphology of fertilization events has been related to successful implantation by subjective criteria (pronuclei score, pronuclei symmetry and position). This work first described these events by time-lapse technology and then compared the timings of fertilization events (second polar body extrusion, first and second pronuclei appearance, abuttal and fading) in implanted versus nonimplanted embryos in a 2-year cohort retrospective study. A total of 1448 transferred embryos from 842 patients undergoing intracytoplasmic sperm injection with oocyte donation were monitored, 212 embryos from treatments where the number of gestational sacs matched the number of transferred embryos and 687 emb…
Measurement uncertainty estimation of a virtual instrument
2002
The law of uncertainty propagation is applied to a PC-based virtual instrument. According to the "guide to the expression of uncertainty in measurement", the measuring model and the various sources of uncertainty have been taken into account. The expressions of the combined output uncertainty in various basic digital signal processing blocks, are obtained starting from each input sample absolute accuracy, without taking into account the parameters which regard the overall behavior of an acquisition board, such as the effective number of bits. In order to verify this procedure, the results obtained by means of the theoretical analysis, are compared with the ones obtained from numerical simul…
The clinical benefit of instituting a prospective clinical community-acquired respiratory virus surveillance program in allogeneic hematopoietic stem…
2019
Highlights • Rapid detection methods used as first diagnostic test for CARVs may delayed the start of antiviral therapy in a significant number of influenza and RSV cases. • Syndromic multiplex RT-PCR-based prospective clinical CARV survey in allo-HCT recipients translates into a lower mortality rate as compared to standard clinical practice based on RSV and influenza virus rapid detection test. • We found that donor/recipient HLA mismatch, CARV LRTD and high-risk ISI were also associated with higher mortality.
Systems Biology and immune aging
2014
Many alterations of innate and adaptive immunity are common in the aging population, which reflect a deterioration of the immune system, and have lead to the terms "immune aging" or "immunosenescence". Systems Biology aims to the comprehensive knowledge of the structure, dynamics, control and design that define a given biological system. Systems Biology benefits from the continuous advances in the omics sciences, based on high-throughput and high-content technologies, as well as on bioinformatic tools for data mining and integration. The Systems Biology approach is becoming gradually used to propose and to test comprehensive models of aging, both at the level of the immune system and the wh…
Biomedical applications of ion mobility-enhanced data-independent acquisition-based label-free quantitative proteomics.
2014
Mass spectrometry-based proteomics greatly benefited from recent improvements in instrument performance and the development of bioinformatics solutions facilitating the high-throughput quantification of proteins in complex biological samples. In addition to quantification approaches using stable isotope labeling, label-free quantification has emerged as the method of choice for many laboratories. Over the last years, data-independent acquisition approaches have gained increasing popularity. The integration of ion mobility separation into commercial instruments enabled researchers to achieve deep proteome coverage from limiting sample amounts. Additionally, ion mobility provides a new dimens…
Label-free profiling of skeletal muscle using high-definition mass spectrometry
2014
We report automated and time efficient (2 h per sample) profiling of muscle using ultra-performance liquid chromatography (LC) coupled directly with high-definition mass spectrometry (HDMSE). Soluble proteins extracted from rat gastrocnemius (n=10) were digested with trypsin and analysed in duplicate using a 90 min RPLC gradient. Protein identification and label-free quantitation were performed from HDMSE spectra analysed using TransOmics Informatics for Proteomics software. In total 1,514 proteins were identified. Of these, 811 had at least 3 unique peptides and were subsequently used to assess the dynamic range and precision of LC-HDMSE label-free profiling. Proteins analysed by LC-HDMSE …