Search results for "CQ"
showing 10 items of 1801 documents
Conductas de riesgo y actitudes relacionadas con la infección por vih/sida en hsh
2014
Abstract:The aim of this investigation is to analyze sexual risk behaviors and attitudes for HIV/AIDS infection of MSM. The ENSI was administrated to 202 men, 168 homosexuals and 24 bisexuals, from 14 to 57 years. The results show a high confidence in condoms as a method of HIV prevention (75.7% very effective and 28.1% effective); however the systematic use of a condom is moderate in anal intercourse (54.64%) and in vaginal intercourse (49.05%) and very low in oral sex (6.22%). There is a low perceived probability (20.28%) and moderate fear (41.25%) become infected with HIV. 20.3% report having drunk alcohol in the last relationship and 5.4% say other drugs. These results should be conside…
WRN protects against topo I but not topo II inhibitors by preventing DNA break formation
2008
The Werner syndrome helicase/3′-exonuclease (WRN) is a major component of the DNA repair and replication machinery. To analyze whether WRN is involved in the repair of topoisomerase-induced DNA damage we utilized U2-OS cells, in which WRN is stably down-regulated (wrn-kd), and the corresponding wild-type cells (wrn-wt). We show that cells not expressing WRN are hypersensitive to the toxic effect of the topoisomerase I inhibitor topotecan, but not to the topoisomerase II inhibitor etoposide. This was shown by mass survival assays, colony formation and induction of apoptosis. Upon topotecan treatment WRN deficient cells showed enhanced DNA replication inhibition and S-phase arrest, whereas af…
Musculoskeletal ultrasound in hemophilia: Results and recommendations from a global survey and consensus meeting
2021
Abstract Introduction For persons with hemophilia, optimization of joint outcomes is an important unmet need. The aim of this initiative was to determine use of ultrasound in evaluating arthropathy in persons with hemophilia, and to move toward consensus among hemophilia care providers regarding the preferred ultrasound protocols for global adaptation. Methods A global survey of hemophilia treatment centers was conducted that focused on understanding how and why ultrasound was being used and endeavored to move toward consensus definitions of both point‐of‐care musculoskeletal ultrasound (POC‐MSKUS) and full diagnostic ultrasound, terminology to describe structures being assessed by ultrasou…
Anticipatory postural adjustments during joint action coordination
2019
International audience; There is a current claim that humans are able to effortlessly detect others’ hidden mental state by simply observing their movements and transforming the visual input into motor knowledge to predict behaviour. Using a classical paradigm quantifying motor predictions, we tested the role of vision feedback during a reach and load-lifting task performed either alone or with the help of a partner. Wrist flexor and extensor muscle activities were recorded on the supporting hand. Early muscle changes preventing limb instabilities when participants performed the task by themselves revealed the contribution of the visual input in postural anticipation. When the partner perfo…
Corporate entrepreneurship and governance: Mergers and acquisitions in Europe
2022
Mergers and acquisitions (M&A) are a form of corporate entrepreneurship involving strategic decisions that require discussion and approval by the board of directors of the acquiring firm. We focus on board attributes to analyze the entrepreneurial function of the board of directors and its involvement in corporate entrepreneurship. Building on different theories (agency theory, resource dependence theory, stewardship theory, and stakeholder theory), we examine whether board composition affects the number of acquisitions, the risk involved in bids, and the creation of value for the acquirer's shareholders. For a sample of European firms over the period 2002 to 2020, we find that board size a…
La vegetazione a protezione di processi di escavazione localizzata: risultati di uno studio sperimentale
2018
Diversi studi di letteratura mostrano come la vegetazione debba essere considerata un fattore chiave per analizzare i meccanismi di trasporto che si realizzano lungo un corso d’acqua naturale (Jarvela, 2002; Folkard, 2011). In particolare, la presenza di vegetazione sul fondo e/o sulle sponde del corso d’acqua contribuisce sia a stabilizzare i sedimenti che ad aumentare la resistenza al moto della corrente (Tsujimoto 1999; Nepf and Vivoni, 2000; Afzalimehr and Dey, 2009; Nepf, 2012), influenzando i processi di trasporto solido e i conseguenti fenomeni di erosione e di deposito lungo lo stesso corso d’acqua. In questo contesto, nel presente lavoro sono riportati alcuni risultati di uno studi…
Analisi dell’evoluzione della degradazione del fondo in alvei a fondo non uniforme
1998
Ricostruzione automatica della morfologia del fondo di un modello fluviale
1998
Glucocorticoid excess and COVID-19 disease
2020
AbstractThe pandemic of coronavirus disease (COVID-19), a disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is causing high and rapid morbidity and mortality. Immune system response plays a crucial role in controlling and resolving the viral infection. Exogenous or endogenous glucocorticoid excess is characterized by increased susceptibility to infections, due to impairment of the innate and adaptive immune system. In addition, diabetes, hypertension, obesity and thromboembolism are conditions overrepresented in patients with hypercortisolism. Thus patients with chronic glucocorticoid (GC) excess may be at high risk of developing COVID-19 infection with a sever…
Opere di sistemazione idraulico-forestale
2019
Il volume illustra, nella visione unitaria del sistema “bacino idrografico”, i processi fisici, le problematiche applicative e le tipologie di intervento disponibili per la sistemazione del reticolo fluviale e dei versanti. Il trasporto solido delle correnti a pelo libero viene introdotto con l’intento di esaminare i processi evolutivi del cavo fluviale, di fornire indicazioni per la progettazione delle opere di correzione ed inalveazione del tracciato del corso d’acqua e di stabilire l’influenza dell’inserimento di manufatti sul delicato equilibrio del sistema fluviale. La trattazione, seguendo il percorso della corrente dalle propaggini più montane fino allo sbocco a mare, esamina opere c…