Search results for "CSI"

Health outcomes of children born after IVF/ICSI: a review of current expert opinion and literature

2014

The Sixth Evian Annual Reproduction (EVAR) Workshop Group Meeting was held to evaluate the impact of IVF/intracytoplasmic sperm injection on the health of assisted-conception children. Epidemiologists, reproductive endocrinologists, embryologists and geneticists presented data from published literature and ongoing research on the incidence of genetic and epigenetic abnormalities and congenital malformations in assisted-conception versus naturally conceived children to reach a consensus on the reasons for potential differences in outcomes between these two groups. IVF-conceived children have lower birthweights and higher peripheral fat, blood pressure and fasting glucose concentrations than …

Preconception genome medicine: current state and future perspectives to improve infertility diagnosis and reproductive and health outcomes based on i…

2021

Abstract BACKGROUND Our genetic code is now readable, writable and hackable. The recent escalation of genome-wide sequencing (GS) applications in population diagnostics will not only enable the assessment of risks of transmitting well-defined monogenic disorders at preconceptional stages (i.e. carrier screening), but also facilitate identification of multifactorial genetic predispositions to sub-lethal pathologies, including those affecting reproductive fitness. Through GS, the acquisition and curation of reproductive-related findings will warrant the expansion of genetic assessment to new areas of genomic prediction of reproductive phenotypes, pharmacogenomics and molecular embryology, fur…

Failures (with some successes) of assisted reproduction and gamete donation programs

2013

Although the possibilities for the treatment of infertility have been improved tremendously, not every couple will be treated successfully.Crude overall pregnancy rates of 50-65% per patient can be achieved nowadays, irrespective of the type of profertility treatment applied first.IVF only accounts for about 20% of the pregnancies achieved. Dropout is an important reason for not reaching the estimated pregnancy rate. Even after failed IVF, spontaneous pregnancies do occur. Sperm and oocyte donation (OD) offer additional chances to subfertile couples. Severity of the male factor (in sperm donation) and young donor age (in OD) are important determinants of success.Analysis of assisted reprodu…

The experience of building and operating COMPASS RICH-1

2010

COMPASS RICH-1 is a large size gaseous Imaging Cherenkov Detector providing hadron identification in the range from 3 to 55 GeV/c, in the wide acceptance spectrometer of the COMPASS Experiment at CERN SPS. It uses a 3 m long C(4)F(10) radiator, a 21 m(2) large VUV mirror surface and two kinds of photon detectors: MAPMTs and MWPCs with CsI photocathodes, covering a total of 5.5 m(2). It is in operation since 2002 and its performance has increased in time thanks to progressive optimization and mostly to a major upgrade which was implemented in 2006. The main characteristics of COMPASS RICH-1 components are described and some specific aspects related to the radiator gas system, the mirror alig…

Probing the Merits of Different Event Parameters for the Identification of Light Charged Particles in CHIMERA CsI(Tl Detectors With Digital Pulse Sha…

2013

We investigated the merits of different event parameters in the identification of Light Charged Particles (LCPs) with CsI(Tl) scintillators read out by photodiodes at high incident energy (400 MeV/u). This investigation is made possible by digital signal processing the output signals. As in the conventional analogue case, the digitized signals allow the discrimination of light charged particles by computing the fast and slow components. In addition other identification parameters as the rise time of the output pulses of the CsI(Tl) come out nearly for free. Aim of this paper is the investigation of novel identification plots and the probe of their merits, in particular at relativistic energ…

Valor de los estudios cromosómicos en espermatozoides mediante la técnica de hibridación in situ fluorescente (FISH) en parejas estériles

2013

Los varones estériles presentan una frecuencia elevada de anomalías citogenéticas, algunas de ellas detectables mediante el cariotipo, pero otras limitadas a las células germinales como resultado de meiosis anormales. Con las nuevas técnicas de reproducción asistida como la Inyección Intracitoplásmica de Espermatozoides (ICSI), la fecundación por espermatozoides cromosómicamente anormales puede dar lugar a fallos de implantación, abortos de repetición y a la transmisión de anomalías cromosómicas a la descendencia. La hibridación in situ fluorescente (FISH) de espermatozoides es una técnica de análisis citogenético que, mediante el marcado de los cromosomas con moléculas de ADN fluorescentes…

Shock-cloud interaction in the Vela SNR II. Hydrodynamic model

2006

In the framework of the study of the X-ray and optical emission in supernova remnants we focus on an isolated X-ray knot in the northern rim of the Vela SNR (Vela FilD), whose X-ray emission has been studied and discussed in Paper I. We aim at understanding the physical origin of the X-ray and optical emission in FilD, at understanding the role of the different physical processes at work, and at obtaining a key for the interpretation of future X-ray observations of SNRs. To this end we have pursued an accurate ``forward'' modeling of the interaction of the Vela SNR shock with an ISM cloud. We perform hydrodynamic simulations and we directly compare the observables synthesized from the simul…

Effects of work exposure to electromagnetic waves and organic compounds on sperm DNA fragmentation in patients undergoing ICSI

2011

Towards water operations of the future.

2018

Nowadays multiple use of “smart” word is provided in many fields including research. Sometimes it is a synonym for chic, elegant or straight. A smart water system is not the same as an elegant, glamorous or fashionable system. Instead it operates to fulfil the requirements of producing an acceptable product while keeping the energy and resource requirements at a minimum. However, while cost savings has up until recently been our primary aim of making water and wastewater operations more efficient, there is now a more pressing agenda of sustainability driving the smart agenda. The primary aim of developing our utilities into a higher level of smart is hence moving from a singular focus on co…

Energy Efficiency Optimization for Multi-cell Massive MIMO : Centralized and Distributed Power Allocation Algorithms

2021

This paper investigates the energy efficiency (EE) optimization in downlink multi-cell massive multiple-input multiple-output (MIMO). In our research, the statistical channel state information (CSI) is exploited to reduce the signaling overhead. To maximize the minimum EE among the neighbouring cells, we design the transmit covariance matrices for each base station (BS). Specifically, optimization schemes for this max-min EE problem are developed, in the centralized and distributed ways, respectively. To obtain the transmit covariance matrices, we first find out the closed-form optimal transmit eigenmatrices for the BS in each cell, and convert the original transmit covariance matrices desi…