Search results for "Calcium"

showing 10 items of 1740 documents

Terminal or truncal ligation of the inferior thyroid artery during thyroidectomy? A prospective randomized trial.

2016

Abstract Introduction Thyroidectomy is a common procedure in general and endocrine surgery. The technique of ligation of inferior thyroid artery (ITA) has been invoked as a possible cause of appearance of postoperative hypocalcemia. Methods We performed a prospective randomized study involving 184 patients undergoing total thyroidectomy to evaluate the differences of truncal ligation versus distal ligation of ITA in terms of postoperative hypocalcemia, vocal fold palsy, voice and swallowing impairment. The patients were divided into group A (trunk ligation of ITA) and group B (terminal branches ligation of ITA). Results We evaluated postoperative PTH and calcemia (immediate, 6 and 12 months…

Malemedicine.medical_specialtyThyroid HormonesHormone Replacement Therapymedicine.medical_treatmentThyroid Gland030230 surgery03 medical and health sciences0302 clinical medicineSwallowingHypothyroidismmedicine.arterymedicineHumansVocal cord paralysisProspective StudiesThyroid NoduleVitamin DProspective cohort studyInferior thyroid arteryLigationAgedmultinodular goiterHypocalcemiabusiness.industryThyroidThyroidectomyinferior thyroid artery; multinodular goiter; thyroidectomyGeneral Medicineinferior thyroid arteryMiddle Agedmedicine.diseaseThyroid DiseasesSurgeryEndocrine surgerymedicine.anatomical_structureTreatment Outcome030220 oncology & carcinogenesisAnesthesiaThyroidectomySurgeryCalciumFemalebusinessLigationDeglutition DisordersVocal Cord ParalysisInternational journal of surgery (London, England)
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Identification of calcium sensing receptor (CaSR) mRNA-expressing cells in normal and injured rat brain

2009

Calcium sensing receptor (CaSR), isolated for the first time from bovine and human parathyroid, is a G-protein-coupled receptors that has been involved in diverse physiological functions. At present a complete in vivo work on the identification of CaSR mRNA-expressing cells in the adult brain lacks and this investigation was undertaken in order to acquire more information on cell type expressing CaSR mRNA in the rat brain and to analyse for the first time its expression in different experimental models of brain injury. The expression of CaSR mRNAs was found mainly in scattered cells throughout almost all the brain regions. A double labeling analysis showed a colocalization of CaSR mRNA expr…

Malemedicine.medical_specialtyTime FactorsCentral nervous systemHippocampusCell CountSettore BIO/11 - Biologia MolecolareBiologySettore BIO/09 - Fisiologiachemistry.chemical_compoundSeizuresInternal medicineSettore BIO/10 - BiochimicaCaSRmedicineAnimalsRNA MessengerRats WistarIbotenic AcidMolecular BiologyIn Situ HybridizationNeuronsKainic AcidGeneral NeuroscienceDentate gyrusBrainColocalizationImmunohistochemistryRatsOligodendrogliamedicine.anatomical_structureEndocrinologynervous systemchemistryBrain InjuriesNeurogliaNeurology (clinical)Pyramidal cellCaSR; BrainCalcium sensing receptor (CaSR) isolated for the first time from bovine and human parathyroid is a G-protein-coupled receptors that has been involved in diverse physiological functions. At present a complete in vivo work on the identification of CaSR mRNA-expressing cells in the adult brain lacks and this investigation was undertaken in order to acquire more information on cell type expressing CaSR mRNA in the rat brain and to analyse for the first time its expression in different experimental models of brain injury. The expression of CaSR mRNAs was found mainly in scattered cells throughout almost all the brain regions. A double labeling analysis showed a colocalization of CaSR mRNA expression in neurons and oligodendrocytes whereas it was not found expressed both in the microglia and in astrocytes. One week after kainate-induced seizure CaSR was found in the injured CA3 region of the hippocampus and very interestingly it was found up-regulated in the neurons of CA1-CA2 and dentate gyrus. Similarly 1 week following ibotenic acid injection in the hippocampus CaSR mRNA expression was increased in oligodendrocytes both in the lesioned area and in the contralateral CA1-CA3 pyramidal cell layers and dentate gyrus. One week after needle-induced mechanical lesion an increase of labeled cells expressing CaSR mRNA was observed along the needle track. In conclusion the present results contribute to extend available data on cell type-expressing CaSR in normal and injured brain and could spur to understand the role of CaSR in repairing processes of brain injury.Receptors Calcium-SensingIbotenic acidDevelopmental BiologyAstrocyte
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Effectiveness of theophylline to increase cyclic AMP levels and force of contraction in electrically paced guinea-pig auricles. Comparison with isopr…

1977

The effects of theophylline (3×10−5 M–5×10−3 M), isoprenaline (10−6 M), excess calcium (7.2 mM) and ouabain (3×10−7 M) on force of contraction and c-AMP content were studied in electrically driven (frequency 3 Hz) left auricles isolated from guinea pigs pretreated with reserpine.

Malemedicine.medical_specialtyTime FactorsContraction (grammar)Guinea Pigschemistry.chemical_elementIn Vitro TechniquesCalciumOuabainGuinea pigTheophyllineInternal medicineIsoprenalineCyclic AMPmedicineAnimalsTheophyllineOuabainPharmacologyChemistryMyocardiumCardiac Pacing ArtificialIsoproterenolGeneral MedicineReserpineMyocardial ContractionPropranololC++ AMPEndocrinologyCalciumFemalemedicine.drugNaunyn-Schmiedeberg's Archives of Pharmacology
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Effects of clinical and laboratory variables at admission and of in-hospital treatment with cardiovascular drugs on short term prognosis of ischemic …

2011

Abstract Introduction No information exists, to our knowledge, about the possible role of cardiovascular drug administration in the acute phase of ischemic stroke and possible effects on stroke outcome. The aim of our study was to evaluate the relationship between in-hospital treatment with cardiovascular drugs in patients with acute ischemic stroke and some outcome indicators. Methods and Results 1096 subjects enrolled in the GIFA study, who had a main discharge diagnosis of ischemic stroke represent the final sample. Drugs considered for the analysis were the following: ACE-inhibitors (ACEI), angiotensin II receptor blockers (ARBs), statins, calcium-channel-blockers (CCBs), antiplatelet (…

Malemedicine.medical_specialtyTime FactorsEndocrinology Diabetes and MetabolismHypercholesterolemiaMedicine (miscellaneous)Angiotensin II Receptor BlockersCharlson indexAngiotensin-Converting Enzyme InhibitorsComorbidityBrain IschemiaInternal medicineActivities of Daily LivingmedicineHumansIn patientcardiovascular diseasesStrokeGeriatric AssessmentAgedRetrospective StudiesNutrition and Dieteticsbusiness.industryCardiovascular AgentsHeparinmedicine.diseaseCalcium Channel BlockersPrognosisStrokeHospital treatmentItalyIschemic strokeHypertensionPhysical therapyFunctional statusFemaleCardiology and Cardiovascular MedicinebusinessCognition DisordersPlatelet Aggregation Inhibitorsmedicine.drugNutrition, metabolism, and cardiovascular diseases : NMCD
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Metabolic and Cardiovascular Effects of Switching Thiazides to Amlodipine in Hypertensive Patients With and Without Type 2 Diabetes (the Diuretics an…

2020

Background: Different studies have indicated that thiazide diuretics can increase the risk of developing type 2 diabetes (T2D). Therefore, in this study, we investigated whether switching from hydrochlorothiazide (HCTZ) to amlodipine resulted in ameliorating different cardiovascular and metabolic measures in hypertensive patients with or without T2D. Methods: This study [Diuretics and Diabetes Control (DiaDiC)] was a 6-week, single-blind, single-center randomized controlled trial. The first 20 normal glucose-tolerant, 20 prediabetic, and 20 T2D consecutive patients were randomized to continue the previous antihypertensive treatment with HCTZ (12.5-25 mg/day) or to switch from HCTZ to amlodi…

Malemedicine.medical_specialtyTime FactorsEndocrinology Diabetes and MetabolismSodium Chloride Symporter InhibitorsdiureticBlood PressureType 2 diabetesSettore MED/13 - EndocrinologiaInternal medicineInternal MedicineMedicineHumansSingle-Blind MethodAmlodipineSettore MED/49 - Scienze Tecniche Dietetiche ApplicateThiazideAntihypertensive AgentsAgedtreatmentbusiness.industryDrug Substitutioncardiovascularfood and beveragesMiddle Agedmedicine.diseaseCalcium Channel BlockersDiabetes controlHydrochlorothiazideTreatment OutcomeDiabetes Mellitus Type 2ItalyHypertensionCardiologyFemaletype 2 diabetesAmlodipinethiazidebusinessEnergy MetabolismmetabolismBiomarkersmedicine.drugMetabolic syndrome and related disorders
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Effect of different treatments in calcium-free medium on basal tone and contractile responses of guinea pig tracheae.

1995

Acetylcholine (ACh; 0.1 mmol/l) and KCl (80 mmol/l) induce a biphasic contractile response in isolated guinea pig tracheae maintained at 37 degrees C either in the presence or absence of extracellular Ca2+. Exposure of the tissue to Ca(2+)-free solution evokes a significant decrease in basal tone and the sources of Ca2+ appear to be decreased by prolonged agonist stimulation, and even more by successive agonist stimulation. After an incubation period of 20 min in Ca(2+)-containing solution, the response is restored. Mg(2+)-depletion in Ca(2+)-free medium increased the contractile response to ACh, but not to KCl, and delayed the tonic component of the next contraction elicited in Ca(2+)-cont…

Malemedicine.medical_specialtyTime FactorsGuinea Pigschemistry.chemical_elementCalciumPotassium ChlorideGuinea pigBasal (phylogenetics)Tone (musical instrument)Organ Culture TechniquesInternal medicinemedicineExtracellularAnimalsMagnesiumPharmacologyIon TransportContractile responseMuscle SmoothGeneral MedicineFree mediumAcetylcholineTracheaCalcium Channel AgonistsEndocrinologychemistryCalciumAcetylcholinemedicine.drugMuscle ContractionPharmacology
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Leukocyte Rheology Before and After Chemotactic Activation in some Venous Diseases

1999

Abstract Objective: to evaluate leukocyte rheology, polymorphonuclear leukocyte (PMN) membrane fluidity and cytosolic Ca2+ concentration in subjects with post-phlebitic leg syndrome (PPS) and acute deep-venous leg thrombosis (DVT). Subjects: twenty-two subjects with leg PPS and 14 subjects with leg DVT. Methods: we evaluated the leukocyte filtration (unfractionated, mononuclear cells (MN) and PMN), the PMN membrane fluidity and the PMN cytosolic Ca2+ concentration. Subsequently, we evaluated the same PMN variables after in vitro chemotactic activation with 4-phorbol 12-myristate 13-acetate (PMA) and N -formyl-methionyl-leucyl-phenylalanine (fMLP). Results: at baseline we observed a signific…

Malemedicine.medical_specialtyTime FactorsMembrane FluidityNeutrophilsPostphlebitic SyndromeIn Vitro TechniquesNeutrophil activation.Peripheral blood mononuclear cellMonocytesNeutrophil ActivationCytosolWhite blood cell filtrationInternal medicinemedicineMembrane fluidityHumansMedicine(all)Venous ThrombosisPolymorphonuclear leukocytebusiness.industrySignificant differenceChemotaxishemic and immune systemsChronic venous insufficiencyMiddle Agedmedicine.diseaseThrombosisIn vitroChemotaxis LeukocyteCytosolEndocrinologyHemorheologyImmunologyDeep venous thrombosisCalciumFemaleSurgeryCardiology and Cardiovascular MedicinebusinessEuropean Journal of Vascular and Endovascular Surgery
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Effect of previous exercise on fracture healing: a biochemical study with mice.

1974

(1974). Effect of Previous Exercise on Fracture Healing: A Biochemical Study with Mice. Acta Orthopaedica Scandinavica: Vol. 45, No. 1-4, pp. 481-489.

Malemedicine.medical_specialtyTime FactorsNitrogenPhysical Exertionmacromolecular substancesBone healingTritiummedicineAnimalsOrthopedics and Sports MedicineBony CallusWound HealingPhysical Education and Trainingbusiness.industryHexosaminesDNAAdaptation PhysiologicalSurgeryRatsTibial FracturesHydroxyprolineRNA RibosomalSurgeryCalciumbusinessActa orthopaedica Scandinavica
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Osteitis fibrosa cystica

2016

Joint Bone Spine - In Press.Proof corrected by the author Available online since vendredi 27 mai 2016

Malemedicine.medical_specialtyTreatment outcomeMEDLINEOsteitis fibrosa cysticaOsteitis Fibrosa Cystica030209 endocrinology & metabolismRisk Assessment[ SDV.MHEP.RSOA ] Life Sciences [q-bio]/Human health and pathology/Rhumatology and musculoskeletal system03 medical and health sciences0302 clinical medicineRare DiseasesRheumatologymedicineHumansVitamin DComputingMilieux_MISCELLANEOUS030203 arthritis & rheumatologybusiness.industryJoint boneMiddle Agedmedicine.diseaseNephrocalcinosisTreatment OutcomeCalciumRadiologybusinessTomography X-Ray Computed
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Uric acid, phosphate and oxalate stones: treatment and prophylaxis.

2004

Medical treatment for the most commonly encountered types of renal stones is described. Nowadays treatment for uric acid stones is well-defined: alkalinizing urine is easy with drugs that are sufficiently active and well enough managed. Relapse is avoided in a high percentage of patients. Medical treatment of phosphate or calcium stones is a more open question as results are far from satisfactory compared with intra- and extra-corporeal approaches which are often minimally invasive and well accepted by both patient and urologist. Relapses are not easy to control because prophylactic measures such as changes in lifestyle and diet are never activated or because they are adopted for a brief pe…

Malemedicine.medical_specialtyUrologymedicine.medical_treatmentCalcium oxalateUrineLithotripsyRisk AssessmentOxalatechemistry.chemical_compoundKidney CalculiPharmacotherapyLithotripsymedicineHumansCalcium Oxalatebusiness.industryPhosphatePrognosisSurgeryUric AcidchemistryUric acidDrug Therapy CombinationFemalebusinessMedical therapyUrologia internationalis
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