Search results for "Caliza"
showing 10 items of 656 documents
Hsp10: Anatomic distribution, functions, and involvement in human disease
2013
There is growing evidence that molecular chaperones/heat shock proteins are involved in the pathogenesis of a number of human diseases, known as chaperonopathies. A better molecular understanding of the pathogenetic mechanisms is essential for addressing new strategies in diagnostics, therapeutics and clinical management of chaperonopathies, including those in which Hsp10 is involved. This chaperonin has been studied for a long time as a member of the mitochondrial protein-folding machine. However, although in normal cells Hsp10 is mainly localized in the mitochondrial matrix, it has also been found during and after stress in other subcellular compartments, such as cytosol, vesicles and sec…
Über Phosphor‐haltige Heterocyclen, II: Molekül‐ und Kristallstruktur von 1,2,3,4,5‐Pentaphenyl‐1λ 5 ‐phosphol‐1‐on
1976
Die Struktur der Titelsubstanz wurde rontgenographisch aus Diffraktometer-Einkristalldaten bestimmt und bis zu einem konventionellen R von 0.076 verfeinert. Der 5-ring besitzt „envelope”-Konformation. Fehlende Planaritat und Bindungslangenverteilung schliesen eine Elektronendelokalisation im λ5-Phospholsystem aus. Das Propellersystem der Phenylsubstituenten bildet eine Cs-symmetrische Doppelschneckenschraube. Die Struktur besteht aus 14-fach koordinierten Molekulen. On Heterocyclic Systems Containing Phosphorus, II: Molecular and Crystal Structure of 1,2,3,4,5-Pentaphenyl-1 λ5-phosphol-1-one The crystal structure of the title compound has been determined from single crystal X-ray data and r…
Professional development for teachers: a world of change
2009
As the industrialised world shifted to an interdependent and global society, formal schooling was quickly recognised as a major factor in achieving a knowledge society of lifelong learners capable of transforming and revitalising organisations. Teachers were encouraged to engage in learning together to improve teaching and, by extension, improve learning for the children in their care. This article identifies three emerging trends intended to broaden teachers' learning and enhance their practices through continuous professional development: glocalisation, mentoring, and re‐thinking teacher evaluation. The body of the article indicates how these three trends are unfolding in Australia, Engla…
PSA-NCAM is expressed in immature, but not recently generated, neurons in the adult cat cerebral cortex layer II
2011
Neuronal production persists during adulthood in the dentate gyrus and the olfactory bulb, where substantial numbers of immature neurons can be found. These cells can also be found in the paleocortex layer II of adult rodents, but in this case most of them have been generated during embryogenesis. Recent reports have described the presence of similar cells, with a wider distribution, in the cerebral cortex of adult cats and primates and have suggested that they may develop into interneurons. The objective of this study is to verify this hypothesis and to explore the origin of these immature neurons in adult cats. We have analyzed their distribution using immunohistochemical analysis of the …
CRACK PROPAGATION IN FINITE ELEMENTS AUGMENTED WITH EMBEDDED INTERPHASES
2022
In the FE analysis of quasi-brittle materials, one of the main issues is how to correctly capture cracks propagation. In particular, under specific load intensity, strains progressively localize in narrow bands, leading to a global nonlinear softening response until collapse. A variety of FE models have been proposed, which may be separated in two main groups: discrete crack models and continuous models. Discrete crack models introduce a discontinuity along the inter-element boundaries or inside elements (intra-element discontinuity). Continuous models modify the constitutive relations of the local material to better describe its behaviour in presence of a fracture. In the framework of intr…
YIHADISMO, DESRADICALIZACIÓN, ADOCTRINAMIENTO Y DEFENSA SOCIAL
2021
En el presente trabajo se analiza el programa español de intervención en radicalización violenta con internos islamistas en centros penitenciarios desde el punto de vista de la resocialización y poniendo el foco en el respeto por los derechos y libertades fundamentales, pero también, y precisamente por ello, se cuestiona la imbricación de la Instrucción 2/2016, de 25 de octubre, dentro de las políticas securitarias dirigidas a la incapacitación, y particularmente el hecho de que los destinatarios del programa sean incluidos, todos ellos, en los FIES (Ficheros de Internos de Especial Seguimiento).
The THESEUS space mission concept: science case, design and expected performances
2018
THESEUS is a space mission concept aimed at exploiting Gamma-Ray Bursts for investigating the early Universe and at providing a substantial advancement of multi-messenger and time-domain astrophysics. These goals will be achieved through a unique combination of instruments allowing GRB and X-ray transient detection over a broad field of view (more than 1sr) with 0.5¿1 arcmin localization, an energy band extending from several MeV down to 0.3¿keV and high sensitivity to transient sources in the soft X-ray domain, as well as on-board prompt (few minutes) follow-up with a 0.7¿m class IR telescope with both imaging and spectroscopic capabilities. THESEUS will be perfectly suited for addressing …