Search results for "Caliza"
showing 10 items of 656 documents
Protoparvovirus Knocking at the Nuclear Door
2017
Protoparvoviruses target the nucleus due to their dependence on the cellular reproduction machinery during the replication and expression of their single-stranded DNA genome. In recent years, our understanding of the multistep process of the capsid nuclear import has improved, and led to the discovery of unique viral nuclear entry strategies. Preceded by endosomal transport, endosomal escape and microtubule-mediated movement to the vicinity of the nuclear envelope, the protoparvoviruses interact with the nuclear pore complexes. The capsids are transported actively across the nuclear pore complexes using nuclear import receptors. The nuclear import is sometimes accompanied by structural chan…
Visualizing Human Protein‐Protein Interactions and Subcellular Localizations on Cell Images Through CellMap
2020
Visualizing protein data remains a challenging and stimulating task. Useful and intuitive visualization tools may help advance biomolecular and medical research; unintuitive tools may bar important breakthroughs. This protocol describes two use cases for the CellMap (http://cellmap.protein.properties) web tool. The tool allows researchers to visualize human protein-protein interaction data constrained by protein subcellular localizations. In the simplest form, proteins are visualized on cell images that also show protein-protein interactions (PPIs) through lines (edges) connecting the proteins across the compartments. At a glance, this simultaneously highlights spatial constraints that prot…
Outlining a grammaticalization path for the Spanish formula en plan (de): A contribution to crosslinguistic pragmatics
2020
Abstract This article discusses the diachronic development of the Spanish multifunctional formula en plan (with its variant en plan de, literally ‘in plan (of)’ but usually equivalent to English like). The article has two main aims: firstly, to describe the changes that the formula has undergone since its earliest occurrences as a marker in the nineteenth century up to the early 21st century. The diachronic study evinces a process of grammaticalization in three steps: from noun to clause adverbial and then to discourse marker. Secondly, to conduct a contrastive analysis between en plan (de) and the English markers like and kind of/kinda so as to shed new light on the potential existence of …
Verbalization of nominalizations: A typological commentary on the article by Nikki van de Pol
2019
Abstract The present article provides a typological commentary on the article by Nikki van de Pol (2019) on the history of the English gerund. It is shown that in spite of certain idiosyncratic aspects, the history of the verbal gerund illustrates a well-known grammaticalization path of verbalization, whereby deverbal nouns are first grammaticalized into nonfinite forms (participles, infinitives, converbs), and may later be integrated into the verbal paradigm. It is further suggested that the mixed behavior attested for the verbal gerund, which deviates both from the nominal and from the clausal prototype, may be universally supported by constructional polysemy and blending with constructio…
Example Markers at the Intersection of Grammaticalization and Lexicalization
2020
Givon’s words “today’s morphology is yesterday’s syntax” have been widely used to describe grammaticalization, a process of linguistic change which implies an increase in the grammatical status of ...
Denboratik kausara: -nez gero kausazko lokailuaren garapenaz
2019
LABURPENA Lan honetan -nez gero atzizki multzoaren garapena dugu aztergai, lehen testuetatik hasi eta gaurdaino. Denbora lokailuetatik sortu diren beste kausazko lokailu asko bezala, -nez gero batez ere mintza-ekintzak eta antzekoak justifikatzeko erabiltzen da. Hala ere, kausa neutroagoak adierazteko ere erabiltzen da. Gaztelaniaz ez bezala, menpeko perpausaren kokagunea ez da aldatu azken mendeotan eta funtzio informatiboan ere ez dugu aldakuntza handirik ikusten. Sumatzen dugun garapen nagusia da beharbada edukizko kausazko neutroetan maizago erabiltzeko joera. Oro har, -nez gero kausazko menderagailuak, gazt. ya que-rekin baino, antz handiagoa du fr. puisque eta ing. since lokailuekin. …
The debate on medicalization of sexology 2001–2010: a literature study on psychological treatment of sexual problems
2018
The objective of this study is to describe the position of psychological treatment in an era where optimism surrounding pharmacological treatment has raised questions as to whether psychology shoul...
Präpositionale Wortgruppen im Altspanischen: 13.-15. Jahrhundert
2013
Der Untersuchungsgegenstand dieser Dissertation sind präpositionale Wortgruppen (PWG) (locuciones prepositivas) in kastilischen Texten aus dem Mittelalter. Ziel dieser Arbeit ist eine kontrastive Analyse von PWG an Hand von zwei Diskurstraditionen, einer juristischen und einer historischen, während des 13., 14. und 15.Jahrhunderts. Das Hauptkorpus beinhaltet zu jedem Jahrhundert einen juristischen und einen chronistischen Text. Um der Gefahr der einseitigen Konzentration auf juristische und chronistische Texte zu entgehen, werden für jedes Jahrhundert ein zusätzlicher Text aus der Gattung der Literatur ausgewertet (Calila e Dimna, El Conde Lucanor und La Celestina). Ausgangspunkt dieser Arb…
La distribución espacial de los equipamientos geriátricos en la comarca de la Ribera Baixa: un análisis prospectivo para la satisfacción de su demanda
2005
En la sociedad actual, la atención y el cuidado adecuado de nuestros mayores resultan fundamentales si queremos seguir ofreciéndoles calidad de vida. Entre los numerosos medios y equipamientos de asistencia, las residencias aparecen como recurso clave para aquellas personas cuyas necesidades desbordan sus propias capacidades. Así, su localización y acceso aparecen como determinantes tanto en su bienestar como en el de sus familias, al permitirles mantener sus vinculaciones sociofamiliares. Sin embargo, apenas hay instrumentos que organicen territorialmente dichos equipamientos, dejando tales “relaciones de continuidad sociofamiliar” a las leyes del mercado. Es por ello que presentamos aquí …
La ceca de Olkairun y su posible localización = The mint of Olkairun and its possible localization
2018
Este artículo estudia el actual estado de cuestión sobre una de las más raras y problemáticas cecas prerromanas de la Península Ibérica. Tradicionalmente descrita como ceca vascona situada en Navarra, debatimos sobre su posible etnómino y ulterior localización. Un nuevo hallazgo procedente de Cigales (Valladolid) permite plantear un giro interpretativo respecto a las antiguas hipótesis, considerando actualmente la situación de la ceca en un lugar más al sur, quizás sobre la cabecera meridional del valle alto del Ebro.